{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:10:34Z","timestamp":1791839434096,"version":"4.3.4"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T00:00:00Z","timestamp":1726185600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T00:00:00Z","timestamp":1726185600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anaesthesiologie"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1007\/s00101-024-01454-w","type":"journal-article","created":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T17:02:30Z","timestamp":1726246950000},"page":"685-693","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Effect of remimazolam for general anesthesia on postoperative nausea and vomiting","Wirkung von Remimazolam bei Allgemeinan\u00e4sthesie auf postoperative \u00dcbelkeit und Erbrechen"],"prefix":"10.1007","volume":"73","author":[{"given":"Su Yeon","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu Man","family":"Sim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo-Seok","family":"Na","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bon-Wook","family":"Koo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0991-7061","authenticated-orcid":false,"given":"Hyun-Jung","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,13]]},"reference":[{"key":"1454_CR1","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.jclinane.2009.02.015","volume":"22","author":"M Lehmann","year":"2010","unstructured":"Lehmann\u00a0M, Monte\u00a0K, Barach\u00a0P, Kindler\u00a0CH (2010) Postoperative patient complaints: a\u00a0prospective interview study of 12,276 patients. J\u00a0Clin Anesth 22:13\u201321","journal-title":"J Clin Anesth"},{"key":"1454_CR2","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/j.bpa.2020.07.011","volume":"34","author":"J Schwartz","year":"2020","unstructured":"Schwartz\u00a0J, Gan\u00a0TJ (2020) Management of postoperative nausea and vomiting in the context of an Enhanced Recovery after Surgery program. Best Pract Res Clin Anaesthesiol 34:687\u2013700","journal-title":"Best Pract Res Clin Anaesthesiol"},{"key":"1454_CR3","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1213\/ANE.0000000000004833","volume":"131","author":"TJ Gan","year":"2019","unstructured":"Gan\u00a0TJ, Belani\u00a0KG, Bergese\u00a0S et\u00a0al (2019) Fourth consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg 131:411\u2013448","journal-title":"Anesth Analg"},{"key":"1454_CR4","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.bja.2023.11.045","volume":"132","author":"E Au","year":"2024","unstructured":"Au\u00a0E, Zhao\u00a0K, Belley-Cote\u00a0E et\u00a0al (2024) The effect of perioperative benzodiazepine administration on postoperative nausea and vomiting: a\u00a0systematic review and meta-analysis of randomised controlled trials. Br J Anaesth 132:469\u2013482","journal-title":"Br J Anaesth"},{"key":"1454_CR5","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1213\/ANE.0000000000000941","volume":"122","author":"MC Grant","year":"2016","unstructured":"Grant\u00a0MC, Kim\u00a0J, Page\u00a0AJ, Hobson\u00a0D, Wick\u00a0E, Wu\u00a0CL (2016) The effect of intravenous midazolam on postoperative nausea and vomiting: a\u00a0meta-analysis. Anesth Analg 122:656\u2013663","journal-title":"Anesth Analg"},{"key":"1454_CR6","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1213\/ANE.0000000000001062","volume":"122","author":"EJ Ahn","year":"2016","unstructured":"Ahn\u00a0EJ, Kang\u00a0H, Choi\u00a0GJ, Baek\u00a0CW, Jung\u00a0YH, Woo\u00a0YC (2016) The effectiveness of midazolam for preventing postoperative nausea and vomiting: a\u00a0systematic review and meta-analysis. Anesth Analg 122:664\u2013676","journal-title":"Anesth Analg"},{"key":"1454_CR7","first-page":"121","volume":"10","author":"F Rodola","year":"2006","unstructured":"Rodola\u00a0F (2006) Midazolam as an anti-emetic. Eur Rev Med Pharmacol Sci 10:121","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"1454_CR8","first-page":"1","volume":"17","author":"KM Kim","year":"2022","unstructured":"Kim KM (2022) Remimazolam: pharmacological characteristics and clinical applications in anesthesiology. APM 17:1\u201311","journal-title":"APM"},{"key":"1454_CR9","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.3390\/medicina59071197","volume":"59","author":"SC Lee","year":"2023","unstructured":"Lee\u00a0SC, Jung\u00a0JW, Choi\u00a0SR, Chung\u00a0CJ, Lee\u00a0TY, Park\u00a0SY (2023) Comparison of postoperative nausea and vomiting incidence between remimazolam and sevoflurane in tympanoplasty with mastoidectomy: a single-center, double-blind, randomized controlled trial. Medicina 59:1197","journal-title":"Medicina"},{"key":"1454_CR10","doi-asserted-by":"publisher","first-page":"110955","DOI":"10.1016\/j.jclinane.2022.110955","volume":"82","author":"JY Choi","year":"2022","unstructured":"Choi\u00a0JY, Lee\u00a0HS, Kim\u00a0JY et\u00a0al (2022) Comparison of remimazolam-based and propofol-based total intravenous anesthesia on postoperative quality of recovery: a\u00a0randomized non-inferiority trial. J\u00a0Clin Anesth 82:110955","journal-title":"J Clin Anesth"},{"key":"1454_CR11","doi-asserted-by":"publisher","first-page":"264","DOI":"10.7326\/0003-4819-151-4-200908180-00135","volume":"151","author":"D Moher","year":"2009","unstructured":"Moher\u00a0D, Liberati\u00a0A, Tetzlaff\u00a0J, Altman\u00a0DG (2009) Group* P. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151:264\u2013269","journal-title":"Ann Intern Med"},{"key":"1454_CR12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2288-14-135","volume":"14","author":"X Wan","year":"2014","unstructured":"Wan\u00a0X, Wang\u00a0W, Liu\u00a0J, Tong\u00a0T (2014) Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range. BMC Med Res Methodol 14:1\u201313","journal-title":"BMC Med Res Methodol"},{"key":"1454_CR13","doi-asserted-by":"publisher","first-page":"l4898","DOI":"10.1136\/bmj.l4898","volume":"366","author":"JAC Sterne","year":"2019","unstructured":"Sterne\u00a0JAC, Savovic\u00a0J, Page\u00a0MJ et\u00a0al (2019) RoB 2: a\u00a0revised tool for assessing risk of bias in randomised trials. BMJ 366:l4898","journal-title":"BMJ"},{"key":"1454_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1472-6963-4-38","volume":"4","author":"D Atkins","year":"2004","unstructured":"Atkins\u00a0D, Eccles\u00a0M, Flottorp\u00a0S et\u00a0al (2004) Systems for grading the quality of evidence and the strength of recommendations I:\u00a0critical appraisal of existing approaches The GRADE Working Group. BMC Health Serv Res 4:1\u20137","journal-title":"BMC Health Serv Res"},{"key":"1454_CR15","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s00540-020-02788-6","volume":"34","author":"M Doi","year":"2020","unstructured":"Doi\u00a0M, Morita\u00a0K, Takeda\u00a0J, Sakamoto\u00a0A, Yamakage\u00a0M, Suzuki\u00a0T (2020) Efficacy and safety of remimazolam versus propofol for general anesthesia: a\u00a0multicenter, single-blind, randomized, parallel-group, phase\u00a0IIb\/III trial. J\u00a0Anesth 34:543\u2013553","journal-title":"J Anesth"},{"key":"1454_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12871-023-02091-3","volume":"23","author":"E-J Kim","year":"2023","unstructured":"Kim\u00a0E\u2011J, Kim\u00a0C\u2011H, Yoon\u00a0J\u2011Y, Byeon\u00a0G\u2011J, Kim\u00a0HY, Choi\u00a0E\u2011J (2023) Comparison of postoperative nausea and vomiting between remimazolam and propofol in patients undergoing oral and maxillofacial surgery: a\u00a0prospective randomized controlled trial. BMC Anesthesiol 23:1\u20137","journal-title":"BMC Anesthesiol"},{"key":"1454_CR17","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1186\/s12871-023-02104-1","volume":"23","author":"H-J Lee","year":"2023","unstructured":"Lee\u00a0H\u2011J, Lee\u00a0HB, Kim\u00a0YJ, Cho\u00a0H\u2011Y, Kim\u00a0WH, Seo\u00a0J\u2011H (2023) Comparison of the recovery profile of remimazolam with flumazenil and propofol anesthesia for open thyroidectomy. BMC Anesthesiol 23:147","journal-title":"BMC Anesthesiol"},{"key":"1454_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12871-023-02092-2","volume":"23","author":"W Luo","year":"2023","unstructured":"Luo\u00a0W, Sun\u00a0M, Wan\u00a0J et\u00a0al (2023) Efficacy and safety of remimazolam tosilate versus propofol in patients undergoing day surgery: a\u00a0prospective randomized controlled trial. BMC Anesthesiol 23:1\u201312","journal-title":"BMC Anesthesiol"},{"key":"1454_CR19","doi-asserted-by":"crossref","unstructured":"Shi F, Chen Y, Li H, Zhang Y, Zhao T (2022) Efficacy and safety of remimazolam tosilate versus propofol for general anesthesia in cirrhotic patients undergoing endoscopic variceal ligation. IJGM: 583\u2013591","DOI":"10.2147\/IJGM.S345390"},{"key":"1454_CR20","doi-asserted-by":"crossref","unstructured":"Wang L, Wang Y, Ma L et al (2023) Cardiopulmonary adverse events of remimazolam versus propofol during cervical conization: a randomized controlled rrial. DDDT: 1233\u20131243","DOI":"10.2147\/DDDT.S405057"},{"key":"1454_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12871-022-01641-5","volume":"22","author":"J Zhang","year":"2022","unstructured":"Zhang\u00a0J, Wang\u00a0X, Zhang\u00a0Q, Wang\u00a0Z, Zhu\u00a0S (2022) Application effects of remimazolam and propofol on elderly patients undergoing hip replacement. BMC Anesthesiol 22:1\u201310","journal-title":"BMC Anesthesiol"},{"key":"1454_CR22","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1007\/s00540-022-03041-y","volume":"36","author":"Y Hari","year":"2022","unstructured":"Hari\u00a0Y, Satomi\u00a0S, Murakami\u00a0C et\u00a0al (2022) Remimazolam decreased the incidence of early postoperative nausea and vomiting compared to desflurane after laparoscopic gynecological surgery. J\u00a0Anesth 36:265\u2013269","journal-title":"J Anesth"},{"key":"1454_CR23","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1186\/s12871-022-01770-x","volume":"22","author":"SW Song","year":"2022","unstructured":"Song\u00a0SW, Jang\u00a0YN, Yoon\u00a0M\u2011W, Jeon\u00a0Y\u2011G (2022) Quality of recovery in patients administered remimazolam versus those administered an inhalant agent for the maintenance of general anesthesia: a\u00a0randomized control trial. BMC Anesthesiol 22:226","journal-title":"BMC Anesthesiol"},{"key":"1454_CR24","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.2147\/TCRM.S256234","volume":"16","author":"Z Jin","year":"2020","unstructured":"Jin\u00a0Z, Gan\u00a0TJ, Bergese\u00a0SD (2020) Prevention and treatment of postoperative nausea and vomiting (PONV): a review of current recommendations and emerging therapies. TCRM 16:1305\u20131317","journal-title":"TCRM"},{"key":"1454_CR25","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1002\/phar.1806","volume":"36","author":"AM Wesolowski","year":"2016","unstructured":"Wesolowski\u00a0AM, Zaccagnino\u00a0MP, Malapero\u00a0RJ, Kaye\u00a0AD, Urman\u00a0RD (2016) Remimazolam: pharmacologic considerations and clinical role in anesthesiology. Pharmacother J Hum Pharmacol Drug Ther 36:1021\u20131027","journal-title":"Pharmacother J Hum Pharmacol Drug Ther"},{"key":"1454_CR26","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/j.bpa.2017.07.002","volume":"31","author":"HD de Boer","year":"2017","unstructured":"de Boer\u00a0HD, Detriche\u00a0O, Forget\u00a0P (2017) Opioid-related side effects: Postoperative ileus, urinary retention, nausea and vomiting, and shivering. A\u00a0review of the literature. Best Pract Res Clin Anaesthesiol 31:499\u2013504","journal-title":"Best Pract Res Clin Anaesthesiol"},{"key":"1454_CR27","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1016\/j.bpa.2019.09.002","volume":"33","author":"H Beloeil","year":"2019","unstructured":"Beloeil\u00a0H (2019) Opioid-free anesthesia. Best Pract Res Clin Anaesthesiol 33:353\u2013360","journal-title":"Best Pract Res Clin Anaesthesiol"},{"key":"1454_CR28","doi-asserted-by":"publisher","first-page":"1330250","DOI":"10.3389\/fphar.2023.1330250","volume":"14","author":"Z Zhang","year":"2023","unstructured":"Zhang\u00a0Z, Li\u00a0C, Xu\u00a0L et\u00a0al (2023) Effect of opioid-free anesthesia on postoperative nausea and vomiting after gynecological surgery: a\u00a0systematic review and meta-analysis. Front Pharmacol 14:1330250","journal-title":"Front Pharmacol"},{"key":"1454_CR29","doi-asserted-by":"publisher","first-page":"51","DOI":"10.4097\/kjae.2016.69.1.51","volume":"69","author":"H Lim","year":"2016","unstructured":"Lim\u00a0H, Doo\u00a0AR, Son\u00a0JS et\u00a0al (2016) Effects of intraoperative single bolus fentanyl administration and remifentanil infusion on postoperative nausea and vomiting. Korean J Anesthesiol 69:51\u201356","journal-title":"Korean J Anesthesiol"},{"key":"1454_CR30","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/j.bpa.2020.06.001","volume":"34","author":"S Stoops","year":"2020","unstructured":"Stoops\u00a0S, Kovac\u00a0A (2020) New insights into the pathophysiology and risk factors for PONV. Best Pract Res Clin Anaesthesiol 34:667\u2013679","journal-title":"Best Pract Res Clin Anaesthesiol"}],"container-title":["Die Anaesthesiologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00101-024-01454-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00101-024-01454-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00101-024-01454-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T10:02:27Z","timestamp":1727863347000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00101-024-01454-w"}},"subtitle":["A\u00a0systematic review and meta-analysis","Systematischer Review und Metaanalyse"],"short-title":[],"issued":{"date-parts":[[2024,9,13]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["1454"],"URL":"https:\/\/doi.org\/10.1007\/s00101-024-01454-w","relation":{},"ISSN":["2731-6858","2731-6866"],"issn-type":[{"value":"2731-6858","type":"print"},{"value":"2731-6866","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,13]]},"assertion":[{"value":"22 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 July 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 September 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"S.Y.\u00a0Kim, K.M.\u00a0 Sim, H.-S.\u00a0Na, B.-W.\u00a0Koo and H.-J.\u00a0Shin declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Trial registry number: CRD42023456978. This article is a\u00a0meta-analysis and systematic review, therefore, IRB approval was not required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards."}}]}}