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Angesichts der zunehmenden Knappheit und Risiken von Erythrozytenkonzentrattransfusionen bedarf es der Weiterentwicklung fremdblutsparender Ma\u00dfnahmen in der Geburtshilfe.<\/jats:p><jats:p>Die maschinelle Autotransfusion (MAT), als integraler Bestandteil des Patient Blood Management (PBM), erm\u00f6glicht eine Sammlung, Aufbereitung und Retransfusion des patienteneigenen Wundblutes. Trotz zunehmender Evidenz der letzten Jahre, die die Vorteile der MAT aufzeigt, wird das Verfahren bislang bei lediglich 0,07\u202f% aller Geburten mit peripartalen H\u00e4morrhagien an deutschen Krankenh\u00e4usern eingesetzt. Es ist anzunehmen, dass der fehlende Einsatz der MAT einerseits auf Sorgen vor patientenbezogenen Risiken wie iatrogene Fruchtwasserembolie und der maternalen Alloimmunisierung w\u00e4hrend des Einsatzes beruht. Andererseits k\u00f6nnten aber auch die fehlende Anwendung und somit unzureichende Erfahrung im Umgang mit der MAT eine H\u00fcrde in deren Nutzung darstellen.<\/jats:p><jats:p>Der nachfolgende Artikel vermittelt einen \u00dcberblick \u00fcber die aktuelle Evidenz zum Einsatz und zur Sicherheit der MAT in der Geburtshilfe. Um eine praxisnahe Umsetzung zu erleichtern, wurden grunds\u00e4tzliche \u00dcberlegungen und organisatorische Vorkehrungen anhand von Erfahrungswerten von den Universit\u00e4tskliniken W\u00fcrzburg und Frankfurt \u00fcbersichtlich aufbereitet und in Form von Grafiken und Checklisten f\u00fcr die perioperative MAT-Anwendung bei Sectio caesarea bereitgestellt.<\/jats:p>","DOI":"10.1007\/s00101-024-01479-1","type":"journal-article","created":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T17:33:47Z","timestamp":1731605627000},"page":"843-851","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Maschinelle Autotransfusion in der Geburtshilfe\u00a0\u2013 Hintergrund und praktische Umsetzung","Cell salvage in obstetrics\u2014Background and practical implementation"],"prefix":"10.1007","volume":"73","author":[{"given":"Mischa J.","family":"Kotlyar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Neef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Rumpf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Meybohm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Zacharowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Kranke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,14]]},"reference":[{"key":"1479_CR1","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1016\/0002-9378(71)90276-6","volume":"109","author":"K Adamsons","year":"1971","unstructured":"Adamsons\u00a0K, Mueller-Heubach\u00a0E, Myers\u00a0RE (1971) The innocuousness of amniotic fluid infusion in the pregnant rhesus monkey. 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P.\u00a0Meybohm bekam Vortragshonorare und Reisekostenerstattung von CSL Behring GmbH, CSL Vifor GmbH, Pharmacosmos GmbH und Werfen GmbH. P.\u00a0Meybohm ist Mitglied im Vorstand von der Stiftung f\u00fcr Gesundheit, Patientensicherheit und Patient Blood Management (PBM Foundation), Network for the Advancement of Patient Blood Management, Haemostasis and Thrombosis (NATA) sowie Mitglied im St\u00e4ndigen Arbeitskreis des Wissenschaftlichen Beirats \u201eQuerschnitts-Leitlinien zur Therapie mit Blutkomponenten und Plasmaderivaten\u201c. P.\u00a0Kranke erhielt F\u00f6rderungen\/Honorar als Gegenleistung f\u00fcr Beratungen und Vortr\u00e4ge f\u00fcr folgende Firmen: CSL Behring, CSL Vifor, Fresenius Kabi, Pharmacosmos, Sintetica, TEVA Ratiopharm, Senzyme, Pajunk, B. Braun, Amicus Ltd. V.\u00a0Neef erhielt Honorare f\u00fcr Vortr\u00e4ge und Reisekosten von Sysmex, Pharmacosmos, MCN-Kongressorganisation sowie Unterst\u00fctzung von Publikationskosten durch die Goethe-Universit\u00e4t Frankfurt. Die Klinik f\u00fcr An\u00e4sthesiologie, Intensivmedizin und Schmerztherapie des Universit\u00e4tsklinikums Frankfurt an der Goethe-Universit\u00e4t erhielt Unterst\u00fctzung von B.\u00a0Braun Melsungen, CSL Behring, Fresenius Kabi und Vifor Pharma f\u00fcr die Umsetzung des Frankfurter Patient-Blood-Management-Programms. K.\u00a0Zacharowski erhielt Honorare f\u00fcr die Teilnahme an Beiratssitzungen f\u00fcr Haemonetics und Vifor und erhielt Vortragshonorare von CSL Behring, Masimo, Pharmacosmos, Boston Scientific, Salus, iSEP, Edwards, Hemosonics und GE Healthcare. Er ist Principal Investigator des EU-Horizon-2020-Projekts ENVISION (Intelligentes digitales Plug-and-Play-Tool f\u00fcr die Echtzeit-\u00dcberwachung von COVID-19-Patienten und intelligente Entscheidungsfindung auf Intensivstationen) und des Horizon-Europe-2021-Projekts COVend (Biomarker- und KI-gest\u00fctzte FX06-Therapie zur Verhinderung des Fortschreitens von leichten und mittelschweren bis schweren Stadien von COVID-19). Partner f\u00fcr das EU-Horizon-2023-Projekt EDiHTA. K.Z. leitet als CEO die Christoph Lohfert Stiftung sowie die Stiftung f\u00fcr Gesundheit, Patientensicherheit und PBM. M.J.\u00a0Kotlyar und F.\u00a0Rumpf geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}