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In 20\u202f% dieser F\u00e4lle versterben die Patienten innerhalb der ersten 30\u00a0postoperativen Tage. Die maschinelle Beatmung stellt den pulmonalen Gasaustausch w\u00e4hrend der Allgemeinan\u00e4sthesie sicher, kann jedoch selbst zu einer beatmungsassoziierten Lungensch\u00e4digung f\u00fchren. In Analogie zur Beatmung im akuten Lungenversagen wurden verschiedene intraoperative Beatmungsstrategien entwickelt, um postoperative pulmonale Komplikationen zu vermeiden. W\u00e4hrend sowohl bei Ein- wie Zweilungenbeatmung bislang weder durch einen hohen positiven end-exspiratorischen Druck oder eine Individualisierung des\n                    <jats:italic>Driving Pressure<\/jats:italic>\n                    eine konsistente Reduktion postoperativer pulmonaler Komplikationen nachgewiesen werden konnte, deutet sich bei ausgew\u00e4hlten Eingriffen und Risikopatienten jedoch ein positiver Effekt an. Neuere pathophysiologische Konzepte wie die mechanische Beatmungsleistung (Mechanical Power bzw. Intensity) k\u00f6nnten zuk\u00fcnftig helfen, Beatmung zu optimieren und Komplikationen zu reduzieren. Diese \u00dcbersichtsarbeit bietet eine kompakte Zusammenfassung der Pathogenese einer beatmungsassoziierten Lungensch\u00e4digung und diskutiert die neueste verf\u00fcgbare Evidenz sowie das Potenzial aktueller Beatmungskonzepte zur Lungenprotektion.\n                  <\/jats:p>","DOI":"10.1007\/s00101-026-01687-x","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T18:03:03Z","timestamp":1776880983000},"page":"573-578","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["WAKWiN-Mini-Review: intraoperative Beatmung und postoperative pulmonale Komplikationen\u00a0\u2013 aktuelle Evidenz und Konzepte zur Lungenprotektion","WAKWiN minireview: intraoperative ventilation and postoperative pulmonary complications\u2014Current evidence and concepts for lung protection"],"prefix":"10.1007","volume":"75","author":[{"given":"Katharina","family":"Hellenthal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Scharffenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,22]]},"reference":[{"key":"1687_CR1","doi-asserted-by":"publisher","unstructured":"Abbenhuis\u00a0J, Abdulmomen\u00a0A, Abdyli\u00a0A et\u00a0al (2025) Effects of intraoperative higher versus lower positive end-expiratory pressure during one-lung ventilation for thoracic surgery on postoperative pulmonary complications (PROTHOR): a multicentre, international, randomised, controlled, phase 3 trial. 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