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Aber auch vor den damit einhergehenden Gefahren und Komplikationen wird seit Jahrzehnten gewarnt.<\/jats:p>\n                  <jats:p>Im Zuge des Auslaufens des Patentschutzes f\u00fcr Sugammadex im Sommer 2023 schien durch die spezifische Wirkung bei g\u00fcnstigem Nebenwirkungsprofil eine entscheidende Vereinfachung im Management der Muskelrelaxierung erreicht worden zu sein. Knapp zwei Jahre sp\u00e4ter m\u00fcssen wir anmerken, dass aus dieser vorteilhaften Entwicklung trotzdem keine vollumf\u00e4ngliche Sicherheit abgeleitet werden kann, sondern im Zusammenhang mit Muskelrelaxierung weiterhin klinische Risiken bestehen.<\/jats:p>\n                  <jats:p>Deshalb sind in diesem Bereich fundierte physiologische und pharmakologische Kenntnisse ebenso wichtig wie ein konsequent sorgf\u00e4ltiges Arbeiten anhand der aktuellen Vorgaben der an\u00e4sthesiologischen Fachgesellschaften.<\/jats:p>","DOI":"10.1007\/s00101-026-01707-w","type":"journal-article","created":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T09:49:04Z","timestamp":1781862544000},"page":"502-510","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Muskelrelaxierung 2026 \u2013 50\u00a0Jahre Suche nach einem idealen Relaxans","Muscle relaxation 2026\u201450\u00a0years of searching for the ideal relaxant"],"prefix":"10.1007","volume":"75","author":[{"given":"Thomas","family":"Kr\u00f6nauer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Girrbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Simon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel R.","family":"Heller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,19]]},"reference":[{"key":"1707_CR1","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1111\/anae.14914","volume":"75","author":"DR Adams","year":"2020","unstructured":"Adams\u00a0DR, Tollinche\u00a0LE, Yeoh\u00a0CB et\u00a0al (2020) Short-term safety and effectiveness of sugammadex for surgical patients with end-stage renal disease: a two-centre retrospective study. 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