{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:52:09Z","timestamp":1790729529177,"version":"4.1.0"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T00:00:00Z","timestamp":1574121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T00:00:00Z","timestamp":1574121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bundesgesundheitsbl"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die Leptospirose ist eine Zoonose, die bei Mensch und Tier eine gro\u00dfe Bandbreite von Krankheitssymptomen mit sehr milden bis hin zu sehr schweren Verl\u00e4ufen aufweisen kann. In Deutschland ist der Labornachweis einer akuten Infektion meldepflichtig: beim Menschen gem\u00e4\u00df Infektionsschutzgesetz und bei Schweinen und Schafen gem\u00e4\u00df der Verordnung \u00fcber meldepflichtige Tierkrankheiten. Die \u00dcbertragung erfolgt \u00fcber direkten und indirekten Kontakt mit dem Urin infizierter Tiere, wobei Nagetiere als Hauptreservoir gelten. Mit einer durchschnittlichen j\u00e4hrlichen Inzidenz von 0,1 gemeldeten F\u00e4llen pro 100.000 Einwohner ist die Leptospirose in Deutschland eine seltene Erkrankung.<\/jats:p><jats:p>Im Rahmen des vom Bundesministerium f\u00fcr Bildung und Forschung (BMBF) gef\u00f6rderten Projekts \u201eVerbesserung der \u00d6ffentlichen Gesundheit durch ein besseres Verst\u00e4ndnis der Epidemiologie nagetier\u00fcbertragener Krankheiten\u201c (RoBoPub) werden in diesem \u00dcbersichtsartikel aktuelle Kenntnisse zur Leptospirose in Deutschland dargestellt. In einem One-Health-Ansatz werden Informationen zum klinischen Bild, verf\u00fcgbare Pr\u00e4valenzdaten bei Mensch und Tier und Erkenntnisse \u00fcber die Erregerverbreitung, die Wirtsassoziation, die \u00dcbertragung des Erregers sowie die Umweltstabilit\u00e4t zusammengefasst. Dar\u00fcber hinaus werden erste Erkenntnisse zum Einfluss von Populationsschwankungen in Nagetierpopulationen auf das Auftreten der Leptospirose diskutiert. Ziel des \u00dcbersichtsartikels ist es, die Wahrnehmung f\u00fcr diese gegenw\u00e4rtig noch vernachl\u00e4ssigte Erkrankung in Deutschland zu erh\u00f6hen.<\/jats:p><jats:p>In Zukunft sollten auch die im Zuge des Klimawandels m\u00f6glicherweise vermehrt auftretenden erh\u00f6hten Temperaturen und starken Regenf\u00e4lle und die damit einhergehende h\u00e4ufigere Exposition des Menschen mit den Erregern ber\u00fccksichtigt werden.<\/jats:p>","DOI":"10.1007\/s00103-019-03051-4","type":"journal-article","created":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T08:01:36Z","timestamp":1574150496000},"page":"1510-1521","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Leptospirose in Deutschland: Aktuelle Erkenntnisse zu Erregerspezies, Reservoirwirten und Erkrankungen bei Mensch und Tier","Leptospirosis in Germany: current knowledge on pathogen species, reservoir hosts, and disease in humans and animals"],"prefix":"10.1007","volume":"62","author":[{"given":"Lisa H.","family":"Nau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duygu","family":"Emirhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Obiegala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Mylius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Runge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Jacob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadja","family":"Bier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karsten","family":"N\u00f6ckler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Imholt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Below","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Princk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Dreesman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer G.","family":"Ulrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Pfeffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Mayer-Scholl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,11,19]]},"reference":[{"key":"3051_CR1","doi-asserted-by":"crossref","first-page":"e0003898","DOI":"10.1371\/journal.pntd.0003898","volume":"9","author":"F Costa","year":"2015","unstructured":"Costa\u00a0F, Hagan\u00a0JE, Calcagno\u00a0J et\u00a0al (2015) Global morbidity and mortality of Leptospirosis: a systematic review. 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