{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T02:53:38Z","timestamp":1761706418749},"reference-count":74,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T00:00:00Z","timestamp":1594598400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T00:00:00Z","timestamp":1594598400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Helmholtz Zentrum M\u00fcnchen - Deutsches Forschungszentrum f\u00fcr Gesundheit und Umwelt (GmbH)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bundesgesundheitsbl"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Umweltfaktoren wirken sich auf Gesundheit und Wohlbefinden der Bewohnerinnen und Bewohner von St\u00e4dten aus. Sie wirken jedoch nicht nur einzeln auf den Menschen, sondern zeigen m\u00f6gliche synergistische oder antagonistische Effekte. Fragen, die sich daraus ergeben, sind: Wie wirkt eine Kombination von Luftschadstoffen mit anderen Umweltfaktoren auf die Gesundheit? Wie gut sind diese Zusammenh\u00e4nge belegt? Wie k\u00f6nnen diese methodisch betrachtet werden? In diesem Beitrag werden zun\u00e4chst methodische Ans\u00e4tze zur Untersuchung von Kombinationswirkungen verschiedener Umweltfaktoren beschrieben. Anschlie\u00dfend werden Umweltfaktoren untersucht, die zusammen mit verschiedenen Luftschadstoffen auf die menschliche Gesundheit wirken, wie Au\u00dfentemperatur, L\u00e4rm und Pollen sowie das Vorhandensein von Gr\u00fcnfl\u00e4chen. K\u00f6rperliche Bet\u00e4tigung und Ern\u00e4hrung werden in Bezug auf die Minderung von gesundheitlichen Luftschadstoffeffekten angesprochen.<\/jats:p><jats:p>W\u00e4hrend f\u00fcr die Gesundheitseffekte der einzelnen Umweltstressoren h\u00e4ufig klare Evidenz vorliegt, sind f\u00fcr ihr Zusammenspiel inhaltlich noch nicht alle Fragen konsistent beantwortet. Die (statistischen) Methoden m\u00fcssen noch weiterentwickelt werden. Das Verh\u00e4ltnis der unterschiedlichen Umweltfaktoren zueinander macht deutlich, dass auch (Interventions\u2011)Ma\u00dfnahmen zur Verringerung einzelner Faktoren zusammenh\u00e4ngen. So f\u00fchrt etwa im Verkehr der Umstieg von passivem auf aktiven Transport (z.\u202fB. durch sichere Radwege und weitere Ma\u00dfnahmen) zu weniger Luftschadstoffen, langfristig zu geringeren Erh\u00f6hungen der Lufttemperatur und gleichzeitig zu einer Verbesserung der Gesundheit des Einzelnen. Demzufolge liegt in einer sinnvollen Planung der bebauten Umwelt ein gro\u00dfes Potenzial zur Reduktion der Umweltstressoren und zur Verbesserung der Gesundheit und des Wohlbefindens der Menschen.<\/jats:p>","DOI":"10.1007\/s00103-020-03186-9","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T14:02:43Z","timestamp":1594648963000},"page":"962-971","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Kombinierte Effekte verschiedener Umweltfaktoren auf die Gesundheit: Luftschadstoffe, Temperatur, Gr\u00fcnfl\u00e4chen, Pollen und L\u00e4rm"],"prefix":"10.1007","volume":"63","author":[{"given":"Regina","family":"Pickford","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ute","family":"Kraus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Frank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Breitner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iana","family":"Markevych","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,13]]},"reference":[{"key":"3186_CR1","volume-title":"Atmen","author":"H Schulz","year":"2018","unstructured":"Schulz\u00a0H, Karrasch\u00a0S, B\u00f6lke\u00a0G et\u00a0al (2018) Atmen. DGfPuB e.\u202fV. Deutsche Gesellschaft f\u00fcr Pneumologie und Beatmungsmedizin e.\u202fV., Berlin"},{"issue":"4","key":"3186_CR2","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s40572-017-0162-z","volume":"4","author":"M Stafoggia","year":"2017","unstructured":"Stafoggia\u00a0M, Breitner\u00a0S, Hampel\u00a0R, Basagana\u00a0X (2017) Statistical approaches to address multi-pollutant mixtures and multiple exposures: the state of the science. Curr Environ Health Rep 4(4):481\u2013490","journal-title":"Curr Environ Health Rep"},{"issue":"1","key":"3186_CR3","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s40572-017-0124-5","volume":"4","author":"JR Krall","year":"2017","unstructured":"Krall\u00a0JR, Strickland\u00a0MJ (2017) Recent approaches to estimate associations between source-specific air pollution and health. Curr Environ Health Rep 4(1):68\u201378","journal-title":"Curr Environ Health Rep"},{"issue":"1","key":"3186_CR4","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/s12931-019-1117-8","volume":"20","author":"KK Mokoena","year":"2019","unstructured":"Mokoena\u00a0KK, Ethan\u00a0CJ, Yu\u00a0Y, Shale\u00a0K, Liu\u00a0F (2019) Ambient air pollution and respiratory mortality in Xi\u2019an, China: a\u00a0time-series analysis. Respir Res 20(1):139","journal-title":"Respir Res"},{"issue":"1","key":"3186_CR5","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1289\/ehp.1409021","volume":"124","author":"L Dai","year":"2016","unstructured":"Dai\u00a0L, Koutrakis\u00a0P, Coull\u00a0BA, Sparrow\u00a0D, Vokonas\u00a0PS, Schwartz\u00a0JD (2016) Use of the adaptive LASSO method to identify PM2.5 components associated with blood pressure in elderly men: the veterans affairs normative aging study. Environ Health Perspect 124(1):120\u2013125","journal-title":"Environ Health Perspect"},{"key":"3186_CR6","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.envint.2014.05.023","volume":"71","author":"A Zanobetti","year":"2014","unstructured":"Zanobetti\u00a0A, Austin\u00a0E, Coull\u00a0BA, Schwartz\u00a0J, Koutrakis\u00a0P (2014) Health effects of multi-pollutant profiles. Environ Int 71:13\u201319","journal-title":"Environ Int"},{"issue":"2","key":"3186_CR7","first-page":"194","volume":"27","author":"PL Ljungman","year":"2016","unstructured":"Ljungman\u00a0PL, Wilker\u00a0EH, Rice\u00a0MB et\u00a0al (2016) The impact of multipollutant clusters on the association between Fine particulate air pollution and microvascular function. Epidemiology 27(2):194\u2013201","journal-title":"Epidemiology"},{"issue":"9991","key":"3186_CR8","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0140-6736(14)62114-0","volume":"386","author":"A Gasparrini","year":"2015","unstructured":"Gasparrini\u00a0A, Guo\u00a0Y, Hashizume\u00a0M et\u00a0al (2015) Mortality risk attributable to high and low ambient temperature: a\u00a0multicountry observational study. Lancet 386(9991):369\u2013375","journal-title":"Lancet"},{"issue":"1","key":"3186_CR9","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1289\/ehp.1408104","volume":"124","author":"NR Ryti","year":"2016","unstructured":"Ryti\u00a0NR, Guo\u00a0Y, Jaakkola\u00a0JJ (2016) Global association of cold spells and adverse health effects: a systematic review and meta-analysis. Environ Health Perspect 124(1):12\u201322","journal-title":"Environ Health Perspect"},{"issue":"4","key":"3186_CR10","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/s00484-011-0497-3","volume":"56","author":"W Yu","year":"2012","unstructured":"Yu\u00a0W, Mengersen\u00a0K, Wang\u00a0X et al (2012) Daily average temperature and mortality among the elderly: a\u00a0meta-analysis and systematic review of epidemiological evidence. Int J Biometeorol 56(4):569\u2013581","journal-title":"Int J Biometeorol"},{"issue":"10082","key":"3186_CR11","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1016\/S0140-6736(17)30505-6","volume":"389","author":"AJ Cohen","year":"2017","unstructured":"Cohen\u00a0AJ, Brauer\u00a0M, Burnett\u00a0R et al (2017) Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015. Lancet 389(10082):1907\u20131918","journal-title":"Lancet"},{"key":"3186_CR12","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1016\/j.scitotenv.2016.10.070","volume":"575","author":"J Li","year":"2017","unstructured":"Li\u00a0J, Woodward\u00a0A, Hou\u00a0XY et al (2017) Modification of the effects of air pollutants on mortality by temperature: a systematic review and meta-analysis. Sci Total Environ 575:1556\u20131570","journal-title":"Sci Total Environ"},{"issue":"1","key":"3186_CR13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0013-9351(02)00008-7","volume":"92","author":"CJ Gordon","year":"2003","unstructured":"Gordon\u00a0CJ (2003) Role of environmental stress in the physiological response to chemical toxicants. Environ Res 92(1):1\u20137","journal-title":"Environ Res"},{"key":"3186_CR14","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.envint.2018.04.021","volume":"116","author":"K Chen","year":"2018","unstructured":"Chen\u00a0K, Wolf\u00a0K, Breitner\u00a0S et al (2018) Two-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight European urban areas. Environ Int 116:186\u2013196","journal-title":"Environ Int"},{"issue":"1","key":"3186_CR15","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/EDE.0b013e31828ac01b","volume":"25","author":"A Analitis","year":"2014","unstructured":"Analitis\u00a0A, Michelozzi\u00a0P, D\u2019Ippoliti\u00a0D et\u00a0al (2014) Effects of heat waves on mortality: effect modification and confounding by air pollutants. Epidemiology 25(1):15\u201322","journal-title":"Epidemiology"},{"issue":"2","key":"3186_CR16","first-page":"221","volume":"27","author":"MA Kioumourtzoglou","year":"2016","unstructured":"Kioumourtzoglou\u00a0MA, Schwartz\u00a0J, James\u00a0P, Dominici\u00a0F, Zanobetti\u00a0A (2016) PM2.5 and mortality in 207 US cities: modification by temperature and city characteristics. Epidemiology 27(2):221\u2013227","journal-title":"Epidemiology"},{"key":"3186_CR17","volume-title":"Climate Change 2014: Synthesis Report. Contribution of Working Groups I, II and III to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change","author":"IPCC","year":"2014","unstructured":"IPCC (2014) Climate Change 2014: Synthesis Report. Contribution of Working Groups I, II and III to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change. Geneva, Switzerland"},{"issue":"11","key":"3186_CR18","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1289\/ehp.11463","volume":"116","author":"KL Ebi","year":"2008","unstructured":"Ebi\u00a0KL, McGregor\u00a0G (2008) Climate change, tropospheric ozone and particulate matter, and health impacts. Environ Health Perspect 116(11):1449\u20131455","journal-title":"Environ Health Perspect"},{"issue":"11","key":"3186_CR19","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1073\/pnas.1614453114","volume":"114","author":"JL Schnell","year":"2017","unstructured":"Schnell\u00a0JL, Prather\u00a0MJ (2017) Co-occurrence of extremes in surface ozone, particulate matter, and temperature over eastern North America. Proc Natl Acad Sci U S\u00a0A 114(11):2854\u20132859","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6","key":"3186_CR20","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1080\/10962247.2015.1040526","volume":"65","author":"AM Fiore","year":"2015","unstructured":"Fiore\u00a0AM, Naik\u00a0V, Leibensperger\u00a0EM (2015) Air quality and climate connections. J\u00a0Air Waste Manag Assoc 65(6):645\u2013685","journal-title":"J Air Waste Manag Assoc"},{"issue":"1\u20132","key":"3186_CR21","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3402\/tellusa.v26i1-2.9736","volume":"26","author":"PJ Crutzen","year":"1974","unstructured":"Crutzen\u00a0PJ (1974) Photochemical reactions initiated by and influencing ozone in unpolluted tropospheric air. Tellus 26(1\u20132):47\u201357","journal-title":"Tellus"},{"issue":"5","key":"3186_CR22","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/0002-9343(86)90348-7","volume":"81","author":"WR Keatinge","year":"1986","unstructured":"Keatinge\u00a0WR, Coleshaw\u00a0SR, Easton\u00a0JC, Cotter\u00a0F, Mattock\u00a0MB, Chelliah\u00a0R (1986) Increased platelet and red cell counts, blood viscosity, and plasma cholesterol levels during heat stress, and mortality from coronary and cerebral thrombosis. Am J Med 81(5):795\u2013800","journal-title":"Am J Med"},{"issue":"3","key":"3186_CR23","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1097\/EDE.0b013e31816a4325","volume":"19","author":"A Schneider","year":"2008","unstructured":"Schneider\u00a0A, Panagiotakos\u00a0D, Picciotto\u00a0S et\u00a0al (2008) Air temperature and inflammatory responses in myocardial infarction survivors. Epidemiology 19(3):391\u2013400","journal-title":"Epidemiology"},{"issue":"10","key":"3186_CR24","doi-asserted-by":"crossref","first-page":"555","DOI":"10.3109\/08958378.2011.593587","volume":"23","author":"R Ruckerl","year":"2011","unstructured":"Ruckerl\u00a0R, Schneider\u00a0A, Breitner\u00a0S, Cyrys\u00a0J, Peters\u00a0A (2011) Health effects of particulate air pollution: a review of epidemiological evidence. Inhal Toxicol 23(10):555\u2013592","journal-title":"Inhal Toxicol"},{"issue":"12","key":"3186_CR25","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1289\/ehp.1001995","volume":"118","author":"R Hampel","year":"2010","unstructured":"Hampel\u00a0R, Schneider\u00a0A, Bruske\u00a0I et\u00a0al (2010) Altered cardiac repolarization in association with air pollution and air temperature among myocardial infarction survivors. Environ Health Perspect 118(12):1755\u20131761","journal-title":"Environ Health Perspect"},{"issue":"7","key":"3186_CR26","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1136\/jech-2014-203939","volume":"69","author":"A Zanobetti","year":"2015","unstructured":"Zanobetti\u00a0A, Peters\u00a0A (2015) Disentangling interactions between atmospheric pollution and weather. J\u00a0Epidemiol Community Health 69(7):613\u2013615","journal-title":"J Epidemiol Community Health"},{"key":"3186_CR27","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1038\/nclimate2704","volume":"5","author":"L Shi","year":"2015","unstructured":"Shi\u00a0L, Kloog\u00a0I, Zanobetti\u00a0A, Liu\u00a0P, Schwartz\u00a0JD (2015) Impacts of temperature and its variability on mortality in New England. Nat Clim Chang 5:988\u2013991","journal-title":"Nat Clim Chang"},{"key":"3186_CR28","volume-title":"Environmental noise guidelines for the European region, W.R.O.f. Europe","author":"WHO","year":"2018","unstructured":"WHO (2018) Environmental noise guidelines for the European region, W.R.O.f. Europe. WHO, Copenhagen"},{"key":"3186_CR29","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph15020379","author":"E van Kempen","year":"2018","unstructured":"van Kempen E, Casas M, Pershagen G, Foraster M (2018) WHO environmental noise guidelines for the European region: a systematic review on environmental noise and cardiovascular and metabolic effects: a summary. Int J Environ Res Public Health. https:\/\/doi.org\/10.3390\/ijerph15020379","journal-title":"Int J Environ Res Public Health"},{"issue":"16","key":"3186_CR30","first-page":"1","volume":"4","author":"W Babisch","year":"2002","unstructured":"Babisch\u00a0W (2002) The noise\/stress concept, risk assessment and research needs. Noise Health 4(16):1\u201311","journal-title":"Noise Health"},{"key":"3186_CR31","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph15030519","author":"M Basner","year":"2018","unstructured":"Basner M, McGuire S (2018) WHO environmental noise guidelines for the European region: a systematic review on environmental noise and effects on sleep. Int J Environ Res Public Health. https:\/\/doi.org\/10.3390\/ijerph15030519","journal-title":"Int J Environ Res Public Health"},{"issue":"5","key":"3186_CR32","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/s00038-013-0489-7","volume":"58","author":"LF Tetreault","year":"2013","unstructured":"Tetreault\u00a0LF, Perron\u00a0S, Smargiassi\u00a0A (2013) Cardiovascular health, traffic-related air pollution and noise: are associations mutually confounded? A systematic review. Int J Public Health 58(5):649\u2013666","journal-title":"Int J Public Health"},{"key":"3186_CR33","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.envres.2014.05.011","volume":"133","author":"M Sorensen","year":"2014","unstructured":"Sorensen\u00a0M, Luhdorf\u00a0P, Ketzel\u00a0M et\u00a0al (2014) Combined effects of road traffic noise and ambient air pollution in relation to risk for stroke? Environ Res 133:49\u201355","journal-title":"Environ Res"},{"issue":"5","key":"3186_CR34","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/jes.2013.21","volume":"23","author":"J Huang","year":"2013","unstructured":"Huang\u00a0J, Deng\u00a0F, Wu\u00a0S, Lu\u00a0H, Hao\u00a0Y, Guo\u00a0X (2013) The impacts of short-term exposure to noise and traffic-related air pollution on heart rate variability in young healthy adults. J\u00a0Expo Sci Environ Epidemiol 23(5):559\u2013564","journal-title":"J Expo Sci Environ Epidemiol"},{"key":"3186_CR35","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.envint.2017.03.018","volume":"103","author":"L Tzivian","year":"2017","unstructured":"Tzivian\u00a0L, Jokisch\u00a0M, Winkler\u00a0A et al (2017) Associations of long-term exposure to air pollution and road traffic noise with cognitive function\u2014an analysis of effect measure modification. Environ Int 103:30\u201338","journal-title":"Environ Int"},{"key":"3186_CR36","doi-asserted-by":"publisher","DOI":"10.1289\/EHP1272","author":"M Sorensen","year":"2017","unstructured":"Sorensen M, Nielsen OW, Sajadieh A et al (2017) Long-term exposure to road traffic noise and nitrogen dioxide and risk of heart failure: a cohort study. Environ Health Perspect. https:\/\/doi.org\/10.1289\/EHP1272","journal-title":"Environ Health Perspect"},{"key":"3186_CR37","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.envres.2018.06.030","volume":"166","author":"C Twohig-Bennett","year":"2018","unstructured":"Twohig-Bennett\u00a0C, Jones\u00a0A (2018) The health benefits of the great outdoors: A systematic review and meta-analysis of greenspace exposure and health outcomes. Environ Res 166:628\u2013637","journal-title":"Environ Res"},{"key":"3186_CR38","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.landurbplan.2019.02.010","volume":"187","author":"TS Eisenman","year":"2019","unstructured":"Eisenman\u00a0TS, Churkina\u00a0G, Jariwala\u00a0SP et\u00a0al (2019) Urban trees, air quality, and asthma: an interdisciplinary review. Landsc Urban Plan 187:47\u201359","journal-title":"Landsc Urban Plan"},{"key":"3186_CR39","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.envres.2017.06.028","volume":"158","author":"I Markevych","year":"2017","unstructured":"Markevych\u00a0I, Schoierer\u00a0J, Hartig\u00a0T et\u00a0al (2017) Exploring pathways linking greenspace to health: theoretical and methodological guidance. Environ Res 158:301\u2013317","journal-title":"Environ Res"},{"issue":"11","key":"3186_CR40","doi-asserted-by":"crossref","first-page":"e469","DOI":"10.1016\/S2542-5196(19)30215-3","volume":"3","author":"D Rojas-Rueda","year":"2019","unstructured":"Rojas-Rueda\u00a0D, Nieuwenhuijsen\u00a0MJ, Gascon\u00a0M, Perez-Leon\u00a0D, Mudu\u00a0P (2019) Green spaces and mortality: a\u00a0systematic review and meta-analysis of cohort studies. Lancet Planet Health 3(11):e469\u2013e477","journal-title":"Lancet Planet Health"},{"issue":"10","key":"3186_CR41","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1289\/ehp.1308049","volume":"122","author":"P Hystad","year":"2014","unstructured":"Hystad\u00a0P, Davies\u00a0HW, Frank\u00a0L et al (2014) Residential greenness and birth outcomes: evaluating the influence of spatially correlated built-environment factors. Environ Health Perspect 122(10):1095\u20131102","journal-title":"Environ Health Perspect"},{"issue":"10","key":"3186_CR42","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1289\/ehp.1205244","volume":"120","author":"P Dadvand","year":"2012","unstructured":"Dadvand\u00a0P, Sunyer\u00a0J, Basagana\u00a0X et\u00a0al (2012) Surrounding greenness and pregnancy outcomes in four Spanish birth cohorts. Environ Health Perspect 120(10):1481\u20131487","journal-title":"Environ Health Perspect"},{"key":"3186_CR43","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.healthplace.2013.12.001","volume":"26","author":"I Markevych","year":"2014","unstructured":"Markevych\u00a0I, Fuertes\u00a0E, Tiesler\u00a0CM et\u00a0al (2014) Surrounding greenness and birth weight: results from the GINIplus and LISAplus birth cohorts in Munich. Health Place 26:39\u201346","journal-title":"Health Place"},{"key":"3186_CR44","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.scitotenv.2019.05.019","volume":"678","author":"AM Dzhambov","year":"2019","unstructured":"Dzhambov\u00a0AM, Markevych\u00a0I, Lercher\u00a0P (2019) Associations of residential greenness, traffic noise, and air pollution with birth outcomes across Alpine areas. Sci Total Environ 678:399\u2013408","journal-title":"Sci Total Environ"},{"issue":"8","key":"3186_CR45","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1136\/jech-2014-203903","volume":"68","author":"E Fuertes","year":"2014","unstructured":"Fuertes\u00a0E, Markevych\u00a0I, von Berg\u00a0A et\u00a0al (2014) Greenness and allergies: evidence of differential associations in two areas in Germany. J\u00a0Epidemiol Community Health 68(8):787\u2013790","journal-title":"J Epidemiol Community Health"},{"issue":"2","key":"3186_CR46","doi-asserted-by":"crossref","first-page":"91","DOI":"10.18176\/jiaci.0228","volume":"28","author":"M D\u2019Amato","year":"2018","unstructured":"D\u2019Amato\u00a0M, Cecchi\u00a0L, Annesi-Maesano\u00a0I, Amato\u00a0GD (2018) News on climate change, air pollution, and allergic triggers of Asthma. J\u00a0Investig Allergol Clin Immunol 28(2):91\u201397","journal-title":"J Investig Allergol Clin Immunol"},{"issue":"3","key":"3186_CR47","doi-asserted-by":"crossref","first-page":"e124","DOI":"10.1016\/S2542-5196(19)30015-4","volume":"3","author":"LH Ziska","year":"2019","unstructured":"Ziska\u00a0LH, Makra\u00a0L, Harry\u00a0SK et al (2019) Temperature-related changes in airborne allergenic pollen abundance and seasonality across the northern hemisphere: a\u00a0retrospective data analysis. Lancet Planet Health 3(3):e124\u2013e131","journal-title":"Lancet Planet Health"},{"key":"3186_CR48","first-page":"543195","volume":"2014","author":"M Sinha","year":"2014","unstructured":"Sinha\u00a0M, Singh\u00a0RP, Kushwaha\u00a0GS et\u00a0al (2014) Current overview of allergens of plant pathogenesis related protein families. Sci World\u00a0J 2014:543195","journal-title":"Sci World J"},{"issue":"11","key":"3186_CR49","doi-asserted-by":"crossref","first-page":"e80147","DOI":"10.1371\/journal.pone.0080147","volume":"8","author":"I Beck","year":"2013","unstructured":"Beck\u00a0I, Jochner\u00a0S, Gilles\u00a0S et\u00a0al (2013) High environmental ozone levels lead to enhanced allergenicity of birch pollen. Plos One 8(11):e80147","journal-title":"Plos One"},{"key":"3186_CR50","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3389\/fpls.2016.00091","volume":"7","author":"U Frank","year":"2016","unstructured":"Frank\u00a0U, Ernst\u00a0D (2016) Effects of NO2 and ozone on pollen allergenicity. Front Plant Sci 7:91","journal-title":"Front Plant Sci"},{"issue":"8","key":"3186_CR51","doi-asserted-by":"crossref","first-page":"4119","DOI":"10.1021\/acs.est.6b04908","volume":"51","author":"K Reinmuth-Selzle","year":"2017","unstructured":"Reinmuth-Selzle\u00a0K, Kampf\u00a0CJ, Lucas\u00a0K et al (2017) Air pollution and climate change effects on allergies in the Anthropocene: abundance, interaction, and modification of allergens and adjuvants. Environ Sci Technol 51(8):4119\u20134141","journal-title":"Environ Sci Technol"},{"issue":"8","key":"3186_CR52","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1172\/JCI24422","volume":"115","author":"I Boldogh","year":"2005","unstructured":"Boldogh\u00a0I, Bacsi\u00a0A, Choudhury\u00a0BK et al (2005) ROS generated by pollen NADPH oxidase provide a\u00a0signal that augments antigen-induced allergic airway inflammation. J\u00a0Clin Invest 115(8):2169\u20132179","journal-title":"J Clin Invest"},{"issue":"2","key":"3186_CR53","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1159\/000099079","volume":"143","author":"F Rogerieux","year":"2007","unstructured":"Rogerieux\u00a0F, Godfrin\u00a0D, Senechal\u00a0H et\u00a0al (2007) Modifications of Phleum pratense grass pollen allergens following artificial exposure to gaseous air pollutants (O(3), NO(2), SO(2)). Int Arch Allergy Immunol 143(2):127\u2013134","journal-title":"Int Arch Allergy Immunol"},{"issue":"11","key":"3186_CR54","doi-asserted-by":"crossref","first-page":"e111712","DOI":"10.1371\/journal.pone.0111712","volume":"9","author":"JM Albertine","year":"2014","unstructured":"Albertine\u00a0JM, Manning\u00a0WJ, DaCosta\u00a0M, Stinson\u00a0KA, Muilenberg\u00a0ML, Rogers\u00a0CA (2014) Projected carbon dioxide to increase grass pollen and allergen exposure despite higher ozone levels. Plos One 9(11):e111712","journal-title":"Plos One"},{"key":"3186_CR55","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.envpol.2014.10.004","volume":"196","author":"G Chassard","year":"2015","unstructured":"Chassard\u00a0G, Choel\u00a0M, Gosselin\u00a0S et\u00a0al (2015) Kinetic of NO2 uptake by Phleum pratense pollen: chemical and allergenic implications. Environ Pollut 196:107\u2013113","journal-title":"Environ Pollut"},{"key":"3186_CR56","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/940243","author":"H Senechal","year":"2015","unstructured":"Senechal\u00a0H, Visez\u00a0N, Charpin\u00a0D et\u00a0al (2015) A review of the effects of major atmospheric pollutants on pollen grains, pollen content, and allergenicity. ScientificWorldJournal. https:\/\/doi.org\/10.1155\/2015\/940243","journal-title":"ScientificWorldJournal"},{"issue":"6","key":"3186_CR57","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1289\/ehp.0901622","volume":"118","author":"M Zuurbier","year":"2010","unstructured":"Zuurbier\u00a0M, Hoek\u00a0G, Oldenwening\u00a0M et\u00a0al (2010) Commuters\u2019 exposure to particulate matter air pollution is affected by mode of transport, fuel type, and route. Environ Health Perspect 118(6):783\u2013789","journal-title":"Environ Health Perspect"},{"issue":"4","key":"3186_CR58","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1136\/oemed-2014-102106","volume":"72","author":"NJ Kubesch","year":"2015","unstructured":"Kubesch\u00a0NJ, de Nazelle\u00a0A, Westerdahl\u00a0D et al (2015) Respiratory and inflammatory responses to short-term exposure to traffic-related air pollution with and without moderate physical activity. Occup Environ Med 72(4):284\u2013293","journal-title":"Occup Environ Med"},{"issue":"7","key":"3186_CR59","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1164\/rccm.201510-2036OC","volume":"194","author":"JE Fisher","year":"2016","unstructured":"Fisher\u00a0JE, Loft\u00a0S, Ulrik\u00a0CS et\u00a0al (2016) Physical activity, air pollution, and the risk of asthma and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 194(7):855\u2013865","journal-title":"Am J Respir Crit Care Med"},{"issue":"9","key":"3186_CR60","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1249\/MSS.0000000000001632","volume":"50","author":"M Laeremans","year":"2018","unstructured":"Laeremans\u00a0M, Dons\u00a0E, Avila-Palencia\u00a0I et al (2018) Black carbon reduces the beneficial effect of physical activity on lung function. Med Sci Sports Exerc 50(9):1875\u20131881","journal-title":"Med Sci Sports Exerc"},{"key":"3186_CR61","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.ypmed.2015.02.009","volume":"74","author":"T Gotschi","year":"2015","unstructured":"Gotschi\u00a0T, Tainio\u00a0M, Maizlish\u00a0N, Schwanen\u00a0T, Goodman\u00a0A, Woodcock\u00a0J (2015) Contrasts in active transport behaviour across four countries: how do they translate into public health benefits? Prev Med 74:42\u201348","journal-title":"Prev Med"},{"key":"3186_CR62","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ypmed.2015.04.010","volume":"76","author":"N Mueller","year":"2015","unstructured":"Mueller\u00a0N, Rojas-Rueda\u00a0D, Cole-Hunter\u00a0T et al (2015) Health impact assessment of active transportation: a systematic review. Prev Med 76:103\u2013114","journal-title":"Prev Med"},{"key":"3186_CR63","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ypmed.2016.02.002","volume":"87","author":"M Tainio","year":"2016","unstructured":"Tainio\u00a0M, de Nazelle\u00a0AJ, Gotschi\u00a0T et\u00a0al (2016) Can air pollution negate the health benefits of cycling and walking? Prev Med 87:233\u2013236","journal-title":"Prev Med"},{"issue":"20","key":"3186_CR64","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1016\/j.jacc.2011.06.063","volume":"58","author":"D Mozaffarian","year":"2011","unstructured":"Mozaffarian\u00a0D, Wu\u00a0JH (2011) Omega\u20113 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events. J\u00a0Am Coll Cardiol 58(20):2047\u20132067","journal-title":"J Am Coll Cardiol"},{"issue":"16","key":"3186_CR65","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1016\/j.jacc.2018.12.093","volume":"73","author":"Z Lin","year":"2019","unstructured":"Lin\u00a0Z, Chen\u00a0R, Jiang\u00a0Y et al (2019) Cardiovascular benefits of fish-oil supplementation against fine particulate air pollution in China. J\u00a0Am Coll Cardiol 73(16):2076\u20132085","journal-title":"J Am Coll Cardiol"},{"issue":"7","key":"3186_CR66","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1289\/ehp.1104472","volume":"120","author":"H Tong","year":"2012","unstructured":"Tong\u00a0H, Rappold\u00a0AG, Diaz-Sanchez\u00a0D et al (2012) Omega\u20113 fatty acid supplementation appears to attenuate particulate air pollution-induced cardiac effects and lipid changes in healthy middle-aged adults. Environ Health Perspect 120(7):952\u2013957","journal-title":"Environ Health Perspect"},{"issue":"9","key":"3186_CR67","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1289\/ehp.10578","volume":"116","author":"I Romieu","year":"2008","unstructured":"Romieu\u00a0I, Garcia-Esteban\u00a0R, Sunyer\u00a0J et al (2008) The effect of supplementation with omega\u20113 polyunsaturated fatty acids on markers of oxidative stress in elderly exposed to PM(2.5). Environ Health Perspect 116(9):1237\u20131242","journal-title":"Environ Health Perspect"},{"issue":"11","key":"3186_CR68","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1289\/ehp.1408988","volume":"123","author":"H Tong","year":"2015","unstructured":"Tong\u00a0H, Rappold\u00a0AG, Caughey\u00a0M et\u00a0al (2015) Dietary supplementation with olive oil or fish oil and vascular effects of concentrated ambient particulate matter exposure in human volunteers. Environ Health Perspect 123(11):1173\u20131179","journal-title":"Environ Health Perspect"},{"key":"3186_CR69","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17020630","author":"J Barthelemy","year":"2020","unstructured":"Barthelemy J, Sanchez K, Miller MR, Khreis H (2020) New opportunities to mitigate the burden of disease caused by traffic related air pollution: antioxidant-rich diets and supplements. Int J Environ Res Public Health. https:\/\/doi.org\/10.3390\/ijerph17020630","journal-title":"Int J Environ Res Public Health"},{"issue":"Pt A","key":"3186_CR70","doi-asserted-by":"crossref","first-page":"108751","DOI":"10.1016\/j.envres.2019.108751","volume":"179","author":"JO Klompmaker","year":"2019","unstructured":"Klompmaker\u00a0JO, Janssen\u00a0NAH, Bloemsma\u00a0LD et al (2019) Residential surrounding green, air pollution, traffic noise and self-perceived general health. Environ Res 179(Pt A):108751","journal-title":"Environ Res"},{"key":"3186_CR71","doi-asserted-by":"publisher","DOI":"10.1289\/EHP3857","author":"JO Klompmaker","year":"2019","unstructured":"Klompmaker JO, Janssen NAH, Bloemsma LD et\u00a0al (2019) Associations of combined exposures to surrounding green, air pollution, and road traffic noise with cardiometabolic diseases. Environ Health Perspect. https:\/\/doi.org\/10.1289\/EHP3857","journal-title":"Environ Health Perspect"},{"key":"3186_CR72","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.envint.2019.05.040","volume":"129","author":"JO Klompmaker","year":"2019","unstructured":"Klompmaker\u00a0JO, Hoek\u00a0G, Bloemsma\u00a0LD et\u00a0al (2019) Associations of combined exposures to surrounding green, air pollution and traffic noise on mental health. Environ Int 129:525\u2013537","journal-title":"Environ Int"},{"issue":"10159","key":"3186_CR73","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1016\/S0140-6736(18)32225-6","volume":"392","author":"GRF Collaborators","year":"2018","unstructured":"Collaborators\u00a0GRF (2018) Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990\u20132017: a\u00a0systematic analysis for the Global Burden of Disease Study 2017. Lancet 392(10159):1923\u20131994","journal-title":"Lancet"},{"key":"3186_CR74","first-page":"3","volume":"7","author":"M Schulz","year":"2006","unstructured":"Schulz\u00a0M (2006) Einf\u00fchrung in die Epidemiologie Teil 5: Interpretation von Assoziationen\u2014Confounding und Effektmodifikation. Ern\u00e4hrungslehre Prax 7:3","journal-title":"Ern\u00e4hrungslehre Prax"}],"container-title":["Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00103-020-03186-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00103-020-03186-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00103-020-03186-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T15:32:07Z","timestamp":1667403127000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00103-020-03186-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,13]]},"references-count":74,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["3186"],"URL":"https:\/\/doi.org\/10.1007\/s00103-020-03186-9","relation":{},"ISSN":["1436-9990","1437-1588"],"issn-type":[{"value":"1436-9990","type":"print"},{"value":"1437-1588","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,13]]},"assertion":[{"value":"13 July 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"I.\u00a0Markevych wird durch das Projekt \u201eNeuroSmog: Determining the impact of air pollution on the developing brain\u201c (Nr. POIR.04.04.00-1763\/18-00) unterst\u00fctzt, das als Teil des TEAM-NET-Programms der Stiftung f\u00fcr Polnische Wissenschaft durchgef\u00fchrt wird, co-finanziert durch EU Mittel aus dem Europ\u00e4ischen Fonds f\u00fcr regionale Entwicklung unter dem \u201eSmart Growth Operational Programme\u201c. R.\u00a0Pickford, U.\u00a0Kraus, U.\u00a0Frank, S.\u00a0Breitner und A.\u00a0Schneider geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}