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In Deutschland haben sich bis zum Ende Juni 2021 \u00fcber 3,7\u202fMio. Menschen infiziert. Das Infektionsgeschehen betrifft jedoch nicht alle Bev\u00f6lkerungsgruppen gleichm\u00e4\u00dfig. Einige Gruppen haben ein besonders hohes Risiko, sich zu infizieren oder nach der Infektion schwere Coronavirus-Disease-2019(COVID-19)-Verl\u00e4ufe zu erleiden.<\/jats:p><jats:p>Der vorliegende narrative Review vermittelt eine \u00dcbersicht \u00fcber die Bev\u00f6lkerungsgruppen in Deutschland, welche besonders von COVID-19 betroffen sind. Au\u00dferdem werden die bisher identifizierten Risikofaktoren beschrieben, die mit Krankenhausaufenthalten oder schweren COVID-19-Verl\u00e4ufen assoziiert sind.<\/jats:p><jats:p>SARS-CoV-2-\u00dcbertragungen finden an den verschiedensten Orten und in unterschiedlichen Situationen statt. Besonders betroffen erscheinen bestimmte berufliche Umgebungen, wie z.\u202fB. die Fleisch verarbeitende Industrie, aber auch Freizeitaktivit\u00e4ten und Gro\u00dfveranstaltungen. Es wurden im Laufe der Pandemie Komorbidit\u00e4ten identifiziert, die mit einem erh\u00f6hten Hospitalisierungsrisiko oder einem schweren COVID-19-Verlauf assoziiert sind, z.\u202fB. vorbestehende Lungen\u2011, Herz-Kreislauf- und Stoffwechselkrankheiten. Patientinnen und Patienten nach Organtransplantation und Personen mit Downsyndrom (Trisomie\u00a021) haben nach einer SARS-CoV-2-Infektion das h\u00f6chste Risiko f\u00fcr eine station\u00e4re Behandlung.<\/jats:p><jats:p>Die identifizierten Rahmenbedingungen, die eine SARS-CoV-2-Verbreitung beg\u00fcnstigen, und das Wissen um besonders vulnerable Bev\u00f6lkerungsgruppen bilden eine wichtige Evidenzgrundlage f\u00fcr die Planung von Pr\u00e4ventionsstrategien und Ma\u00dfnahmen zur Pandemiebek\u00e4mpfung.<\/jats:p>","DOI":"10.1007\/s00103-021-03391-0","type":"journal-article","created":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T16:05:09Z","timestamp":1627574709000},"page":"1107-1115","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["COVID-19-Patientinnen und -Patienten in Deutschland: Expositionsrisiken und assoziierte Faktoren f\u00fcr Hospitalisierungen und schwere Krankheitsverl\u00e4ufe"],"prefix":"10.1007","volume":"64","author":[{"given":"Uwe","family":"Koppe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hendrik","family":"Wilking","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Harder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Haas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ute","family":"Rexroth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamah","family":"Hamouda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,7,29]]},"reference":[{"key":"3391_CR1","unstructured":"WHO Coronavirus (COVID-19) dashboard. https:\/\/covid19.who.int\/. 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