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Alle STI-Tests m\u00fcssen nun einer strengeren \u00dcberpr\u00fcfung unterzogen werden. Fortschritte in der PoCT-Entwicklung haben die Testm\u00f6glichkeiten f\u00fcr HIV, Syphilis und Hepatitis\u00a0C verbessert, insbesondere durch pr\u00e4qualifizierte Tests der WHO. Die in Deutschland verf\u00fcgbaren HIV-Selbsttests detektieren jedoch nur die Antik\u00f6rperkomponente, sodass ein negatives Ergebnis erst 12\u00a0Wochen nach Exposition sicher aussagekr\u00e4ftig ist. F\u00fcr Syphilis gibt es PoCT f\u00fcr das Antik\u00f6rperscreening, die jedoch im Labor einer Best\u00e4tigung bed\u00fcrfen. F\u00fcr Chlamydien\u2011, Gonokokken- und Mykoplasmeninfektionen ist die PoCT-Qualit\u00e4t gr\u00f6\u00dftenteils noch unzureichend. Weiterentwicklungen im Bereich der Nukleins\u00e4ureamplifikationstests (NAT) zeigen diesbez\u00fcglich vielversprechende Ans\u00e4tze.<\/jats:p>\n          <jats:p>PoCT sind besonders vorteilhaft f\u00fcr niedrigschwellige Angebote, die sich an marginalisierte Gruppen richten, da sie eine zeitnahe Diagnosestellung und Behandlung im Rahmen des Testsettings erm\u00f6glichen. Herausforderungen bleiben jedoch die Qualit\u00e4tssicherung und m\u00f6gliche psychologische Belastungen durch falsch-positive Ergebnisse. Es besteht weiterhin die Notwendigkeit einer kontinuierlichen Weiterentwicklung und Integration von PoCT in das Gesundheitssystem, um den Zugang zur Diagnostik zu verbessern und die Verbreitung von Infektionen zu reduzieren.<\/jats:p>","DOI":"10.1007\/s00103-025-04067-9","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T08:59:49Z","timestamp":1749113989000},"page":"1185-1193","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Point-of-Care-Tests f\u00fcr sexuell \u00fcbertragbare Infektionen\u00a0\u2013 was ist der aktuelle Stand?","Point-of-care tests for sexually transmitted infections\u2014what is the current status?"],"prefix":"10.1007","volume":"68","author":[{"given":"Viviane","family":"Bremer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heinrich","family":"Scheiblauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian","family":"Muenchhoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Sch\u00fcttler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"Timm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Baier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Buder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristin","family":"Meyer-Schlinkmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Nei\u00dfe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger","family":"Dumke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gyde","family":"Steffen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"Jansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Brockmeyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,6,5]]},"reference":[{"key":"4067_CR1","unstructured":"UNAIDS (2022) Global HIV and AIDS statistics\u2014Fact sheet. https:\/\/www.unaids.org\/sites\/default\/files\/media_asset\/UNAIDS_FactSheet_en.pdf. 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