{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:31:34Z","timestamp":1790422294680,"version":"4.1.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"}],"funder":[{"DOI":"10.13039\/501100008349","name":"Universit\u00e4t Duisburg-Essen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100008349","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bundesgesundheitsbl"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Hintergrund<\/jats:title>\n                    <jats:p>Seit September 2019 ist die HIV-Pr\u00e4expositionsprophylaxe (PrEP) im Leistungskatalog der Gesetzlichen Krankenversicherung (GKV) enthalten. Ziel des pr\u00e4sentierten Moduls der PrEP-Surv-Studie war ein Monitoring des PrEP-Geschehens in den Jahren 2019 bis 2022 sowie eine Untersuchung der Eignung von GKV-Routinedaten f\u00fcr ein jahrweises Monitoring der PrEP-Versorgung.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methoden<\/jats:title>\n                    <jats:p>PrEP-Nutzende wurden in anonymen Daten der BARMER aus den Jahren 2019 bis 2022 identifiziert und analysiert. Gegenstand der Analysen waren jahrweise eine Bestimmung der Anzahl der PrEP-Nutzenden, eine Deskription der Kohorten hinsichtlich Alter, Geschlecht und Therapietreue, eine Identifikation von HIV-Infektionen sowie die Ermittlung der Raten sexuell \u00fcbertragbarer Infektionen beziehungsweise Infektionskrankheiten (STI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ergebnisse<\/jats:title>\n                    <jats:p>Von 2019 bis 2022 wurde ein Anstieg der PrEP-Nutzendenanzahl von 1058 auf 3194 beobachtet. Demografische Merkmale blieben dabei weitgehend unver\u00e4ndert, w\u00e4hrend die durchschnittliche zensierte Therapietreue von 98\u202f% im Jahr 2019 auf 91\u202f% bis 92\u202f% in den Folgejahren fiel. Bei 2 Personen wurden HIV-Infektionen beobachtet, wobei die Transmissionen mutma\u00dflich nicht unter PrEP-Nutzung stattfanden. Hinsichtlich der STI-Raten waren im Zeitverlauf keine klaren Ver\u00e4nderungen zu beobachten.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Diskussion<\/jats:title>\n                    <jats:p>Die beobachtete Kohorte scheint gut mit anderen PrEP-Kohorten in Deutschland vergleichbar zu sein. Die Stabilit\u00e4t der demografischen Merkmale kann m\u00f6glicherweise ein Hinweis darauf sein, dass Personengruppen mit PrEP-Indikation, die zu Beginn der Kostenerstattung nicht erreicht wurden, auch weiterhin nicht erreicht werden. Neben einer Deskription des PrEP-Geschehens konnte ein Ansatz aufgezeigt werden, wie ein j\u00e4hrliches Monitoring auf Basis von GKV-Routinedaten umsetzbar w\u00e4re.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00103-025-04165-8","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T09:12:35Z","timestamp":1764234755000},"page":"89-96","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Monitoring der HIV-Pr\u00e4expositionsprophylaxe in Deutschland auf Basis von GKV-Routinedaten","Monitoring of HIV pre-exposure prophylaxis in Germany based on statutory health insurance claims data"],"prefix":"10.1007","volume":"69","author":[{"given":"Frederik","family":"Valbert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Kollan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Friebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Voulgaris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Gunsenheimer-Bartmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Wasem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"4165_CR1","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1056\/NEJMoa1108524","volume":"367","author":"JM Baeten","year":"2012","unstructured":"Baeten\u00a0JM, Donnell\u00a0D, Ndase\u00a0P et\u00a0al (2012) Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. 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Es wurden keine interventionellen Studien an Menschen oder Tieren durchgef\u00fchrt. Die Analyse ist nicht von der Deklaration von Helsinki betroffen. Die w\u00e4hrend der vorliegenden Studie analysierten Daten sind als anonyme Routinedaten der BARMER nicht \u00f6ffentlich zug\u00e4nglich. Der Zugang zu dem Wissenschafts-Data-Warehouse der BARMER kann bei der BARMER angefragt werden.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}