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Giftinformationszentren (GIZ) beantworten Expositionsanfragen. Ziel dieser Studie war es, Expositionsanfragen zu Zubereitungen mit pflanzlichen Bestandteilen am Gemeinsamen Giftinformationszentrum Erfurt (GGIZ) auszuwerten, um Pr\u00e4ventionsans\u00e4tze zu identifizieren.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methoden<\/jats:title>\n                    <jats:p>Es wurde eine statistische Auswertung der Expositionsanfragen am GGIZ f\u00fcr 2013\u20132022 durchgef\u00fchrt. Daten aus 9\u00a0Bundesl\u00e4ndern flossen ein. Ber\u00fccksichtigt wurden Anfragen zu Einzelpr\u00e4paraten, die mindestens 10-mal angefragt wurden. Die Symptomschwere wurde mit dem Poisoning Severity Score (PSS) und das Vergiftungsrisiko mit einem modifizierten Litovitz-Risikofaktor berechnet.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ergebnisse<\/jats:title>\n                    <jats:p>\n                      36 Zubereitungen mit 2512 Expositionen (\u00d8251,2\/a; Trend \u03c4\u202f=\u20090,8667,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u20090,0007) wurden identifiziert. 60,2\u202f% (1511) der Betroffenen waren Kleinkinder. 98,5\u202f% (2474) der Expositionen ereigneten sich im h\u00e4uslichen Umfeld. In 64,5\u202f% (1620) geschahen die Expositionen unabsichtlich. 93,4\u202f% (2345) waren oral. 75,3\u202f% (1780\/2365) der Expositionen blieben symptomlos, 23,5\u202f% (556\/2365) hatten leichte\/geringe, 1\u202f% (24) mittlere\/m\u00e4\u00dfige und 0,2\u202f% (5) schwere Symptome. Schwere Intoxikationen traten durch Colchysat\u00ae B\u00fcrger und Klosterfrau\u00ae Melissengeist Konzentrat auf.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Diskussion<\/jats:title>\n                    <jats:p>Kleinkinder sind eine relevante Risikogruppe bei der Anwendung von Zubereitungen mit pflanzlichen Bestandteilen. Pr\u00e4parate mit Colchicin oder Ethanol k\u00f6nnen insbesondere bei intentionalen Expositionen zu t\u00f6dlichen Intoxikationen f\u00fchren. Es wird empfohlen, orale und extraorale Pr\u00e4parate getrennt und au\u00dferhalb der Reichweite Unbefugter zu lagern und umfassende Aufkl\u00e4rung anzubieten.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00103-026-04237-3","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:14:22Z","timestamp":1777457662000},"page":"644-656","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Expositionsanfragen zu Zubereitungen mit pflanzlichen Bestandteilen in Deutschland: Analyse von Anfragen (2013\u20132022) am Gemeinsamen Giftinformationszentrum Erfurt","Exposure inquiries related to preparations containing plant-based ingredients in Germany: analysis of inquiries (2013\u20132022) at the Joint Poison Information Center in Erfurt"],"prefix":"10.1007","volume":"69","author":[{"given":"Sebastian","family":"Wendt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Linden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagmar","family":"Prasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heike","family":"Franke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"4237_CR1","unstructured":"Gemeinsame Giftinformationszentrum Erfurt (2025) Anfragen zu Arzneimitteln. https:\/\/www.ggiz-erfurt.de\/giftinformation.html. 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