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Prognosen zur Krankheitslast sind entsprechend besorgniserregend. Gleichzeitig wurden in der Forschung, insbesondere im Bereich der Risikoreduktion, erhebliche Fortschritte erzielt. So ist eine Vielzahl etablierter Schutz- und Risikofaktoren auf individueller Ebene identifiziert worden und etliche daran ankn\u00fcpfende Interventionsstudien wurden durchgef\u00fchrt. Zunehmend richtet sich der Fokus jedoch auf bev\u00f6lkerungsbezogene Ma\u00dfnahmen zur langfristigen Reduktion der Demenzf\u00e4lle.<\/jats:p>\n                  <jats:p>Dieser Beitrag gibt einen \u00dcberblick \u00fcber den aktuellen Forschungsstand. Ausgehend von der Datenlage zur Krankheitslast wird zun\u00e4chst auf etablierte Risikofaktoren eingegangen. Darauf aufbauend werden neuere, bislang weniger ber\u00fccksichtigte potenzielle Einflussfaktoren erl\u00e4utert, bestehende Interventionsans\u00e4tze zusammengefasst und die Bedeutung bev\u00f6lkerungsbezogener Pr\u00e4ventionsstrategien f\u00fcr Public Health und Gesundheitspolitik eingeordnet.<\/jats:p>","DOI":"10.1007\/s00103-026-04279-7","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T13:38:33Z","timestamp":1784900313000},"page":"1000-1007","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Modifizierbare Risiko- und Schutzfaktoren f\u00fcr Demenz: Etablierte und neue Evidenz im \u00dcberblick","Modifiable risk and protective factors for dementia: an overview of established and emerging evidence"],"prefix":"10.1007","volume":"69","author":[{"given":"Felix G.","family":"Wittmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea E.","family":"Z\u00fclke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Vajnberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Luppa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffi G.","family":"Riedel-Heller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,24]]},"reference":[{"key":"4279_CR1","doi-asserted-by":"publisher","unstructured":"Blotenberg I, Hoffmann W, Thyrian JR (2023) Dementia in Germany: Epidemiology and Prevention Potential. 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