{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:34:05Z","timestamp":1763037245545},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T00:00:00Z","timestamp":1537488000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Chirurg"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1007\/s00104-018-0731-1","type":"journal-article","created":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T19:38:55Z","timestamp":1537558735000},"page":"931-942","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Moderne Wundbehandlung \u2013 von \u201ebest practice\u201c zur Innovation"],"prefix":"10.1007","volume":"89","author":[{"given":"N.","family":"Kirsten","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Herberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Augustin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Tigges","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Behrendt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Heidemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. S.","family":"Debus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Diener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,9,21]]},"reference":[{"issue":"Suppl 1","key":"731_CR1","first-page":"5","volume":"66","author":"M Situm","year":"2012","unstructured":"Situm M, Kolic M (2012) Atypical wounds: definition and classification. Acta Med Croatica 66(Suppl 1):5\u201311","journal-title":"Acta Med. Croatica"},{"key":"731_CR2","first-page":"245","volume-title":"Physiologie","author":"R Klinke","year":"2005","unstructured":"Klinke R, Pape HC, Silbernagel S (2005) Physiologie, 5.\u00a0Aufl. Thieme, Stuttgart, S\u00a0245\u2013253, S.\u00a0653\u2013655","edition":"5"},{"key":"731_CR3","volume-title":"Wundatlas, Kompendium der komplexen Wundbehandlung","author":"H Lippert","year":"2006","unstructured":"Lippert H (2006) Wundatlas, Kompendium der komplexen Wundbehandlung. Thieme, Stuttgart, New York"},{"key":"731_CR4","volume-title":"Expertenstandard Pflege von Menschen mit chronischen Wunden","author":"Deutsches Netzwerk f\u00fcr Qualit\u00e4tsentwicklung in der Pflege","year":"2015","unstructured":"Deutsches Netzwerk f\u00fcr Qualit\u00e4tsentwicklung in der Pflege (2015) Expertenstandard Pflege von Menschen mit chronischen Wunden. Deutsches Netzwerk f\u00fcr Qualit\u00e4tsentwicklung in der Pflege, Osnabr\u00fcck (1. Aktualisierung)"},{"issue":"6","key":"731_CR5","doi-asserted-by":"publisher","first-page":"237","DOI":"10.12968\/jowc.2010.19.6.48471","volume":"19","author":"F Gottrup","year":"2010","unstructured":"Gottrup F, Apelqvist J, Price P (2010) Outcomes in controlled and comparative studies on non-healing wounds: recommendations to improve the quality of evidence in wound management. J\u00a0Wound Care 19(6):237\u2013268","journal-title":"J Wound Care"},{"issue":"5A","key":"731_CR6","doi-asserted-by":"publisher","first-page":"65S","DOI":"10.1016\/S0002-9610(03)00306-4","volume":"187","author":"TA Mustoe","year":"2004","unstructured":"Mustoe TA (2004) Understanding chronis wounds; a\u00a0unifying hypothesis on their pathogenesis and implication for therapy. Am J Surg 187(5A):65S\u201370S","journal-title":"Am J Surg"},{"key":"731_CR7","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-658-13321-4","volume-title":"Versorgungsepidemiologie des Ulcus cruris in Deutschland. Erkrankungsh\u00e4ufigkeit, Versorgungsqualit\u00e4t und Pr\u00e4diktoren der Wundheilung","author":"K Heyer","year":"2016","unstructured":"Heyer K (2016) Versorgungsepidemiologie des Ulcus cruris in Deutschland. Erkrankungsh\u00e4ufigkeit, Versorgungsqualit\u00e4t und Pr\u00e4diktoren der Wundheilung. Springer, Wiesbaden"},{"key":"731_CR8","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.bcmd.2003.09.020","volume":"32","author":"V Falanga","year":"2004","unstructured":"Falanga V (2004) The chronic wound: impaired healing and solutions in the context of wound bed preparation. Blood Cells Mol Dis 32:88\u201394","journal-title":"Blood Cells Mol Dis"},{"key":"731_CR9","first-page":"10","volume":"1","author":"KM Sedlarik","year":"1994","unstructured":"Sedlarik KM (1994) Die Prozesse der Wundheilung. Hartmann WundForum 1:10\u201315","journal-title":"Hartmann WundForum"},{"issue":"4","key":"731_CR10","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1016\/S0733-8635(18)30218-3","volume":"11","author":"RA Clark","year":"1993","unstructured":"Clark RA (1993) Biology of dermal wound repair. Dermatol Clin 11(4):647\u2013666","journal-title":"Dermatol Clin"},{"key":"731_CR11","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.1016\/S0140-6736(05)67700-8","volume":"366","author":"V Falanga","year":"2005","unstructured":"Falanga V (2005) Wound healing and its impairment in the diabetic foot. Lancet 366:1736\u20131743","journal-title":"Lancet"},{"key":"731_CR12","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1056\/NEJM199909023411006","volume":"341","author":"AJ Singer","year":"1999","unstructured":"Singer AJ, Clark RA (1999) Cutaneous wound healing. N\u00a0Engl J Med 341:738\u2013746","journal-title":"N Engl J Med"},{"issue":"2A Suppl","key":"731_CR13","doi-asserted-by":"publisher","first-page":"26S","DOI":"10.1016\/S0002-9610(98)00183-4","volume":"176","author":"WK Stadelmann","year":"1998","unstructured":"Stadelmann WK, Digenis AG, Tobin GR (1998) Physiology and healing dynamics of chronic cutaneous wounds. Am J Surg 176(2A Suppl):26S\u201338S","journal-title":"Am J Surg"},{"key":"731_CR14","series-title":"Gesellschaftspolitische Kommentare \u2013 gpk 2016; Sonderausgabe Nr.\u00a02","first-page":"7","volume-title":"Was geh\u00f6rt zu den Standards? Leitliniengerechte Therapie chronischer Wunden","author":"H Diener","year":"2016","unstructured":"Diener H, Herberger K (2016) Was geh\u00f6rt zu den Standards? Leitliniengerechte Therapie chronischer Wunden. Gesellschaftspolitische Kommentare \u2013 gpk 2016; Sonderausgabe Nr.\u00a02, S\u00a07\u20139"},{"issue":"5","key":"731_CR15","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1089\/wound.2014.0592","volume":"4","author":"DT Ubbink","year":"2015","unstructured":"Ubbink DT, Br\u00f6lmann FE, Go PM et al (2015) Evidence-based care of acute wounds: a perspective. Adv Wound Care 4(5):286\u2013294","journal-title":"Adv Wound Care"},{"key":"731_CR16","volume-title":"Leitlinien zur Hygiene in Klinik und Praxis, Anforderungen der Hygiene bei chronischen und sekund\u00e4r heilenden Wunden, AWMF-Leitlinien-Register, Nr.\u00a0029\/042, Entwicklungsstufe 1 + IDA","author":"Arbeitskreis \u201eKrankenhaus- & Praxishygiene\u201c der AWMF Working Group \u201eHospital & Practice\u201c of AWMF","year":"2014","unstructured":"Arbeitskreis \u201eKrankenhaus- & Praxishygiene\u201c der AWMF Working Group \u201eHospital & Practice\u201c of AWMF (2014) Leitlinien zur Hygiene in Klinik und Praxis, Anforderungen der Hygiene bei chronischen und sekund\u00e4r heilenden Wunden, AWMF-Leitlinien-Register, Nr.\u00a0029\/042, Entwicklungsstufe 1 + IDA"},{"key":"731_CR17","volume-title":"Vol.\u00a04: no. 21, Systematic review of wound care management. AWMF, Leitlinien DGfP, Diagnostik und Therapie des Ulcus cruris venosum","author":"Health Technology Assessment","year":"2000","unstructured":"Health Technology Assessment (2000) Vol.\u00a04: no. 21, Systematic review of wound care management. AWMF, Leitlinien DGfP, Diagnostik und Therapie des Ulcus cruris venosum"},{"key":"731_CR18","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-017-4012-6","author":"K Herberger","year":"2017","unstructured":"Herberger K, Heyer K, Protz K et\u00a0al (2017) Konsensusgruppe Nationaler Konsensus zur Wunddokumentation beim Ulcus cruris Teil\u00a02: Routineversorgung \u2013 Klassifikation der Variablenauspr\u00e4gungen. Hautarzt. \n                    https:\/\/doi.org\/10.1007\/s00105-017-4012-6","journal-title":"Hautarzt"},{"issue":"10","key":"731_CR19","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1007\/s00105-017-3990-8","volume":"68","author":"K Heyer","year":"2017","unstructured":"Heyer K, Milde S, Schmitt J, May M, Helfrich J, Augustin M (2017) Konsensusgruppe. Standarddatensatz f\u00fcr die Evaluation bei Selektivvertr\u00e4gen bei Ulcus cruris. Hautarzt 68(10):815\u2013836 (A standard data set for the evaluation of venous leg ulcers in selective contracts: national consensus)","journal-title":"Hautarzt"},{"issue":"11","key":"731_CR20","first-page":"1057","volume":"11","author":"F Jockenh\u00f6fer","year":"2013","unstructured":"Jockenh\u00f6fer F, Gollnick H, al Herberger Ket (2013) Bacteriological pathogen spectrum of chronic leg ulcers: results of a\u00a0multicenter trial in dermatologic wound care centers differentiated by regions. J\u00a0Dtsch Dermatol Ges 11(11):1057\u20131106","journal-title":"J. Dtsch. Dermatol. Ges."},{"key":"731_CR21","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.niox.2014.11.015","volume":"44","author":"K Heuer","year":"2015","unstructured":"Heuer K, Hoffmanns MA, Demir E et al (2015) The topical use of non-thermal dielectric barrier discharge (DBD): nitric oxide related effects on human skin. Nitric Oxide 44:52\u201360","journal-title":"Nitric Oxide"},{"key":"731_CR22","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1159\/000348331","volume":"226","author":"K Heyer","year":"2013","unstructured":"Heyer K, Augustin M, Protz K, Herberger K, Spehr C, Rustenbach SJ (2013) Effectiveness of advanced versus conventional wound dressings on healing of chronic wounds:systematic review and meta-analysis. Dermatology (Basel) 226:172\u2013184","journal-title":"Dermatology (Basel)"},{"key":"731_CR23","volume-title":"Lokaltherapie chronischer Wunden bei Patienten mit den Risiken periphere arterielle Verschlusskrankheit, Diabetes mellitus, chronische ven\u00f6se Insuffizienz","author":"Deutsche Gesellschaft f\u00fcr Wundheilung und Wundbehandlung e.v.","year":"2012","unstructured":"Deutsche Gesellschaft f\u00fcr Wundheilung und Wundbehandlung e.v. (2012) Lokaltherapie chronischer Wunden bei Patienten mit den Risiken periphere arterielle Verschlusskrankheit, Diabetes mellitus, chronische ven\u00f6se Insuffizienz. \n                    http:\/\/www.awmf-online.de\/\n                    \n                   (Erstellt: 12. Juni 2012). Zugegriffen: 01.06.2018"},{"key":"731_CR24","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.mvr.2016.02.008","volume":"106","author":"T Kisch","year":"2016","unstructured":"Kisch T, Schleusser S, Helmke A et al (2016) The repetitive use of non-thermal dielectric barrier discharge plasma boosts cutaneous microcirculatory effects. Microvasc Res 106:8\u201313","journal-title":"Microvasc Res"},{"issue":"1","key":"731_CR25","first-page":"7","volume":"16","author":"L Gan","year":"2018","unstructured":"Gan L, Zhang S, Poorun D, Liu D, Lu X, He M, Duan X, Chen H (2018) Medical applications of nonthermal atmospheric pressure plasma in dermatology. J\u00a0Dtsch Dermatol Ges 16(1):7\u201313","journal-title":"J Dtsch Dermatol Ges"},{"key":"731_CR26","doi-asserted-by":"publisher","first-page":"477","DOI":"10.4062\/biomolther.2014.105","volume":"22","author":"B Haertel","year":"2014","unstructured":"Haertel B, von Woedtke T, Weltmann K\u2011D, Lindequist U (2014) Non-thermal atmospheric-pressure plasma possible application in wound healing. Biomol Ther (Seoul) 22:477\u2013490","journal-title":"Biomol. Ther. (Seoul)"},{"issue":"3 Suppl","key":"731_CR27","doi-asserted-by":"publisher","first-page":"138S","DOI":"10.1097\/PRS.0000000000002643","volume":"138","author":"OB Hughes","year":"2016","unstructured":"Hughes OB, Rakosi A, Macquhae F, Herskovitz I, Fox JD, Kirsner RS (2016) A review of cellular and acellular matrix products: indications, techniques, and outcomes. Plast Reconstr Surg 138(3 Suppl):138S\u2013147S","journal-title":"Plast Reconstr Surg"},{"issue":"6","key":"731_CR28","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1111\/wrr.12357","volume":"23","author":"VR Driver","year":"2015","unstructured":"Driver VR, Lavery LA, Reyzelman AM, Dutra TG, Dove CR, Kotsis SV, Kim HM, Chung KC (2015) A clinical trial of integra template for diabetic foot ulcer treatment. Wound Repair Regen 23(6):891\u2013900","journal-title":"Wound Repair Regen"},{"issue":"2","key":"731_CR29","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1111\/iwj.12600","volume":"14","author":"CM Zelen","year":"2017","unstructured":"Zelen CM, Orgill DP, Serena T, Galiano R, Carter MJ, DiDomenico LA, Keller J, Kaufman J, Li WW (2017) A prospective, randomised, controlled, multicentre clinical trial examining healing rates, safety and cost to closure of an acellular reticular allogenic human dermis versus standard of care in the treatment of chronic diabetic foot ulcers. Int Wound\u00a0J 14(2):307\u2013315","journal-title":"Int Wound J"},{"issue":"1","key":"731_CR30","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1177\/1534734615573661","volume":"14","author":"BT Baldursson","year":"2015","unstructured":"Baldursson BT, Kjartansson H, Konr\u00e1dsd\u00f3ttir F, Gudnason P, Sigurjonsson GF, Lund SH (2015) Healing rate and autoimmune safety of full-thickness wounds treated with fish skin acellular dermal matrix versus porcine small-intestine submucosa: a\u00a0noninferiority study. Int J Low Extrem Wounds 14(1):37\u201343. \n                    https:\/\/doi.org\/10.1177\/1534734615573661","journal-title":"Int J Low Extrem Wounds"},{"issue":"S1","key":"731_CR31","doi-asserted-by":"publisher","first-page":"383","DOI":"10.7205\/MILMED-D-16-00142","volume":"182","author":"S Magnusson","year":"2017","unstructured":"Magnusson S, Baldursson BT, Kjartansson H, Rolfsson O, Sigurjonsson GF (2017) Regenerative and antibacterial properties of acellular fish skin grafts and human amnion\/chorion membrane: implications for tissue preservation in combat casualty care. Mil Med 182(S1):383\u2013388","journal-title":"Mil Med"},{"key":"731_CR32","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1007\/s00772-017-0333-0","volume":"22","author":"B Dorweiler","year":"2017","unstructured":"Dorweiler B, Trinh TT, D\u00fcnschede F et al (2017) Die marine Omega-3-Wundmatrix zur Behandlung komplizierter Wunden. Gefasschirurgie 22:558\u2013567","journal-title":"Gefasschirurgie"},{"key":"731_CR33","doi-asserted-by":"publisher","first-page":"CD006899","DOI":"10.1002\/14651858.CD006899.pub3","volume":"5","author":"MJ Martinez-Zapata","year":"2016","unstructured":"Martinez-Zapata MJ, Mart\u00ed-Carvajal AJ, Sol\u00e0 I, Exp\u00f3sito JA, Bol\u00edbar I, Rodr\u00edguez L, Garcia J, Zaror C (2016) Autologous platelet-rich plasma for treating chronic wounds. Cochrane Database Syst Rev 5:CD006899. \n                    https:\/\/doi.org\/10.1002\/14651858.CD006899.pub3","journal-title":"Cochrane Database Syst Rev"},{"key":"731_CR34","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006899.pub3","author":"MJ Martinez-Zapata","year":"2016","unstructured":"Martinez-Zapata MJ, Mart\u00ed-Carvajal AJ, Sol\u00e0 I, Exp\u00f3sito JA, Bol\u00edbar I, Rodr\u00edguez L, Garcia J, Zaror C (2016) Autologous platelet-rich plasma for treating chronic wounds. Cochrane Database Syst Rev. \n                    https:\/\/doi.org\/10.1002\/14651858.CD006899.pub3","journal-title":"Cochrane Database Syst Rev"},{"key":"731_CR35","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.avsg.2016.04.023","volume":"38","author":"M Ahmed","year":"2017","unstructured":"Ahmed M, Reffat SA, Hassan A, Eskander F (2017) Platelet-rich plasma for the treatment of clean diabetic foot ulcers. Ann Vasc Surg 38:206\u2013211","journal-title":"Ann Vasc Surg"}],"container-title":["Der Chirurg"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00104-018-0731-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00104-018-0731-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00104-018-0731-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T23:25:05Z","timestamp":1569021905000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00104-018-0731-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,21]]},"references-count":35,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["731"],"URL":"https:\/\/doi.org\/10.1007\/s00104-018-0731-1","relation":{},"ISSN":["0009-4722","1433-0385"],"issn-type":[{"value":"0009-4722","type":"print"},{"value":"1433-0385","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,21]]},"assertion":[{"value":"21 September 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"N.\u00a0Kirsten, K.\u00a0Herberger, M.\u00a0Augustin, W.\u00a0Tigges, C.\u00a0Behrendt, F.\u00a0Heidemann, E.S.\u00a0Debus und H.\u00a0Diener geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"Dieser Beitrag beinhaltet keine von den Autoren durchgef\u00fchrten Studien an Menschen oder Tieren.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}