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Ein Screeningprogramm f\u00fcr Gef\u00e4\u00dferkrankungen bei asymptomatischen Personen mit definierter Risikokonstellation kann zu einer fr\u00fchen Diagnose f\u00fchren.<\/jats:p><\/jats:sec><jats:sec><jats:title>Ziel der Arbeit<\/jats:title><jats:p>Die Studie untersucht ein Screeningprogramm auf Karotisstenosen, periphere arterielle Verschlusskrankheit (pAVK) und abdominelle Aortenaneurysmen (AAA) bei Menschen ohne anamnestisch bekannte arterielle Gef\u00e4\u00dferkrankungen hinsichtlich demografischer Daten, Risikofaktoren, Vorerkrankungen, Medikamenteneinnahme sowie Detektion und Therapie pathologischer Befunde.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material und Methoden<\/jats:title><jats:p>Probanden wurden durch verschiedene Informationsmaterialien eingeladen, ein Fragebogen erfasste kardiovaskul\u00e4re Risikofaktoren. Das Screening erfolgte mit ABI-Messung und Duplexsonographie als monozentrische, prospektive, einarmige Studie innerhalb eines Jahres. Endpunkte waren die Pr\u00e4valenz von Risikofaktoren, pathologische und\/oder behandlungsbed\u00fcrftige Befunde.<\/jats:p><\/jats:sec><jats:sec><jats:title>Ergebnisse<\/jats:title><jats:p>Es nahmen 391 Personen teil, bei 36,0\u202f% bestand mindestens ein kardiovaskul\u00e4rer Risikofaktor, 35,5\u202f% wiesen zwei und 14,4\u202f% drei oder mehr auf. Aus der Sonographie der Karotiden resultierte bei 9\u202f% ein kontrollbed\u00fcrftiger Befund mit einer &lt;\u202f50%igen bis &gt;\u202f75%igen Stenose oder eines Verschlusses. Ein AAA mit einem Durchmesser von 3,0\u20134,5\u202fcm wurde bei 0,9\u202f% nachgewiesen, ein pathologischer ABI\u202f&lt;\u20090,9 oder &gt;\u202f1,3 bei 12,3\u202f%. Bei 17,0\u202f% bestand befundbasiert die Indikation einer Pharmakotherapie, bei keinem die einer Operation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Diskussion<\/jats:title><jats:p>Es zeigte sich die Durchf\u00fchrbarkeit eines Screeningprogramms auf das Vorliegen einer Karotisstenose, einer pAVK und eines AAA bei definierten Risikopersonen. Es wurden kaum behandlungsbed\u00fcrftige Gef\u00e4\u00dfpathologien im Einzugsgebiet der Klinik nachgewiesen, sodass ein Einsatz des Programms in Deutschland in dieser Form derzeit auf Basis der Daten nicht empfohlen werden kann.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00104-023-01821-0","type":"journal-article","created":{"date-parts":[[2023,2,23]],"date-time":"2023-02-23T16:30:20Z","timestamp":1677169820000},"page":"342-348","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ergebnisse eines monozentrischen Gef\u00e4\u00dfscreeningprogramms in Deutschland","Results of a\u00a0single center vascular screening program in Germany"],"prefix":"10.1007","volume":"94","author":[{"given":"K.","family":"Passek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Ronellenfitsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Meisenbacher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Peters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"B\u00f6ckler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,2,20]]},"reference":[{"key":"1821_CR1","doi-asserted-by":"publisher","DOI":"10.1080\/13557858.2022.2139815","author":"SNB Abdul Latip","year":"2022","unstructured":"Abdul Latip\u00a0SNB, Chen\u00a0SE, Im\u00a0YR et\u00a0al (2022) Systematic review of randomised controlled trials on interventions aimed at promoting colorectal cancer screening amongst ethnic minorities. 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