{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:27:30Z","timestamp":1791829650409,"version":"4.3.4"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T00:00:00Z","timestamp":1701043200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T00:00:00Z","timestamp":1701043200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005713","name":"Technische Universit\u00e4t M\u00fcnchen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005713","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Chirurgie"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n                <jats:title>Hintergrund<\/jats:title>\n                <jats:p>Milztumoren sind selten und k\u00f6nnen gerade als bildgebender Zufallsbefund eine differenzialdiagnostische Herausforderung darstellen. Aufgrund fehlender gro\u00dfangelegter Biopsiestudien ist die zur Verf\u00fcgung stehende Literatur hinsichtlich eindeutiger bildgebender Dignit\u00e4tskriterien begrenzt.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ziel der Arbeit\/Fragestellung<\/jats:title>\n                <jats:p>Die vorliegende Arbeit soll die Chancen einer gezielten \u00e4rztlichen Anamneseerhebung sowie die M\u00f6glichkeiten und Limitationen der multimodalen Sonographie aufzeigen, um mit einfachen und schonenden Methoden zur richtigen Diagnose bei einem Milzherd zu kommen.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Material und Methoden<\/jats:title>\n                <jats:p>Selektive Literaturrecherche und klinische Kasuistiken.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Bei der Differenzialdiagnostik fokaler Milzl\u00e4sionen ist die Information \u00fcber bestehende h\u00e4matoonkologische bzw. inflammatorisch-rheumatologische Vorerkrankungen essenziell, um gerade auch Zufallsbefunde korrekt einzuordnen. Neben B\u2011Bild-Ultraschall (B-US) und farbkodierter Dopplersonographie (FKDS) liefert vor allem die kontrastverst\u00e4rkte Sonographie (CEUS) differenzialdiagnostisch entscheidende Hinweise. W\u00e4hrend im B\u2011US echoreiche oder arteriell hypervaskularisierte Milzherde in der FKDS\/CEUS meist benigne sind, m\u00fcssen echoarme und arteriell hypoperfundierte Herde weiter abgekl\u00e4rt werden. Die ultraschallgesteuerte Milzbiopsie hat zwar ein h\u00f6heres Blutungsrisiko als die Leberbiopsie, ist aber dennoch die schonendste und effektivste Methode, um bei richtiger Indikationsstellung die histologische Kl\u00e4rung von Milzherden zu erreichen.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Diskussion\/Schlussfolgerung<\/jats:title>\n                <jats:p>Durch die Kombination aus Anamnese und multimodalen Ultraschallmethoden, ggf. erg\u00e4nzt durch die sonographisch gesteuerte Biopsie, lassen sich fokale Milzl\u00e4sionen in den meisten F\u00e4llen erfolgreich einteilen mit direkten Auswirkungen auf das weitere klinische Vorgehen.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00104-023-02018-1","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T15:03:08Z","timestamp":1701097388000},"page":"1000-1008","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Multimodale Ultraschalltechniken zur Differenzialdiagnose von Milzherden\u00a0\u2013 eine diagnostische Herausforderung","Multimodal ultrasound techniques for the differential diagnosis of splenic lesions \u2014 A\u00a0diagnostic challenge"],"prefix":"10.1007","volume":"94","author":[{"given":"Konrad Friedrich","family":"Stock","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Slotta-Huspenina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajo","family":"Findeisen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"G\u00f6rg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,27]]},"reference":[{"key":"2018_CR1","volume-title":"Ultraschall 2023, 46. 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