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In den letzten Jahrzehnten konnten durch effektivere Chemotherapie und verbesserte Operationstechniken sowie durch internationale Kooperationen erhebliche Fortschritte erzielt werden. Die Herausforderungen f\u00fcr die chirurgische Therapie bleiben hoch. In Deutschland ergeben sich diesbez\u00fcglich spezifische Schwierigkeiten.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ziel der Arbeit<\/jats:title>\n                    <jats:p>Zusammenfassung der aktuellen Evidenz zur chirurgischen Behandlung p\u00e4diatrischer Lebertumoren, Analyse der Versorgungsstrukturen in Deutschland und Entwicklung von Perspektiven zur Optimierung der Therapie.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material und Methoden<\/jats:title>\n                    <jats:p>Narrative \u00dcbersicht aktueller Evidenz, systematische Analyse der chirurgischen Ergebnisse vorangegangener Hepatoblastomstudien, Auswertung deutscher Versorgungspfade und dadurch Identifikation von Problemen und Perspektiven.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ergebnisse<\/jats:title>\n                    <jats:p>Ma\u00dfgeblich f\u00fcr die verbesserte Prognose von Kindern mit Lebertumoren (v.\u202fa. Hepatoblastom) sind multimodale, risikoadaptierte Therapiekonzepte und verbesserte Operationsstrategien. Aufgrund der Seltenheit von Leberresektionen im Kindesalter befindet sich die p\u00e4diatrische Lebertumorchirurgie in Deutschland an einer Schnittstelle zwischen Kinder\u2011, Viszeral- und Transplantationschirurgie. Chirurgisch entscheidend sind kindgerechte Operationsstrategien zur Erh\u00f6hung der Resektionsrate und Vermeidung postoperativer Komplikationen. Eine direkte \u00dcbertragung von Erkenntnissen aus der Leberchirurgie bei Erwachsenen birgt hohe Risiken. In Deutschland bestehen gute Grundvoraussetzungen, die Versorgung kann jedoch durch verbesserte Kommunikation mit Referenzstrukturen, intelligente Zentralisierungsans\u00e4tze und Investition in die chirurgische Ausbildung verbessert werden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Diskussion<\/jats:title>\n                    <jats:p>Die Lebertumorchirurgie bei Kindern ist aufgrund ihrer Seltenheit und des hohen Anspruchs mit spezifischen Herausforderungen verbunden. In Deutschland kann die St\u00e4rkung multidisziplin\u00e4rer Strukturen und Kommunikation sowie eine effiziente Zentralisierung der Therapieplanung die Patientensicherheit und Behandlungsergebnisse f\u00fcr Kinder mit Lebertumoren weiter optimieren.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00104-025-02438-1","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T14:59:43Z","timestamp":1767797983000},"page":"206-217","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Chirurgische Behandlung von Kindern mit Lebertumoren in Deutschland","Surgical management of children with liver tumors in Germany"],"prefix":"10.1007","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2484-8615","authenticated-orcid":false,"given":"Juri","family":"Fuchs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph W.","family":"Michalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"G\u00fcnther","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"2438_CR1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.4103\/0971-9261.142001","volume":"19","author":"DC Aronson","year":"2014","unstructured":"Aronson\u00a0DC, Czauderna\u00a0P, Maibach\u00a0R et\u00a0al (2014) The treatment of hepatoblastoma: Its evolution and the current status as per the SIOPEL trials. 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