{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T08:38:43Z","timestamp":1792571923613,"version":"4.5.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Chirurgie"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1007\/s00104-026-02579-x","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T16:48:30Z","timestamp":1790095710000},"page":"860-866","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Operative Behandlung prim\u00e4r maligner Knochentumoren","Surgical treatment of primary malignant bone tumors"],"prefix":"10.1007","volume":"97","author":[{"given":"Arne","family":"Streitb\u00fcrger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jendrik","family":"Hardes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina Myline","family":"Engel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,22]]},"reference":[{"issue":"27","key":"2579_CR1","doi-asserted-by":"publisher","first-page":"4323","DOI":"10.1200\/JCO.22.02767","volume":"41","author":"SS Bielack","year":"2023","unstructured":"Bielack\u00a0SS et\u00a0al (2023) Prognostic Factors in High-Grade Osteosarcoma of theExtremities or Trunk: An Analysis of 1,702 Patients Treatedon Neoadjuvant Cooperative Osteosarcoma Study GroupProtocols. J\u00a0Clin Oncol 41(27):4323\u20134337","journal-title":"J Clin Oncol"},{"key":"2579_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2023.113260","volume":"192","author":"P Heesen","year":"2023","unstructured":"Heesen\u00a0P et\u00a0al (2023) Association between local treatment modalities and event-free survival, overall survival, and local recurrence in patients with localised Ewing Sarcoma. Report from the Ewing 2008 trial. Eur J Cancer 192:113260","journal-title":"Eur J Cancer"},{"issue":"415","key":"2579_CR3","first-page":"4","volume":"2003","author":"WF Enneking","year":"1980","unstructured":"Enneking\u00a0WF, Spanier\u00a0SS, Goodman\u00a0MA (1980) A system for the surgical staging of musculoskeletal sarcoma. Clin Orthop Relat Res 2003(415):4\u201318","journal-title":"Clin Orthop Relat Res"},{"issue":"3","key":"2579_CR4","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1097\/01.mph.0000155860.38641.83","volume":"27","author":"G Bacci","year":"2005","unstructured":"Bacci\u00a0G et\u00a0al (2005) Primary high-grade osteosarcoma: comparison between preadolescent and older patients. J\u00a0Pediatr Hematol Oncol 27(3):129\u2013134","journal-title":"J Pediatr Hematol Oncol"},{"issue":"3","key":"2579_CR5","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1007\/s11999-016-4851-y","volume":"475","author":"LM Jeys","year":"2017","unstructured":"Jeys\u00a0LM et\u00a0al (2017) A Novel System for the Surgical Staging of Primary High-grade Osteosarcoma: The Birmingham Classification. Clin Orthop Relat Res 475(3):842\u2013850","journal-title":"Clin Orthop Relat Res"},{"issue":"6","key":"2579_CR6","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1016\/j.trecan.2022.02.007","volume":"8","author":"J Almagro","year":"2022","unstructured":"Almagro\u00a0J et\u00a0al (2022) Tissue architecture in tumor initiation and progression. Trends Cancer 8(6):494\u2013505","journal-title":"Trends Cancer"},{"key":"2579_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2022.101737","volume":"41","author":"MC Nogaro","year":"2022","unstructured":"Nogaro\u00a0MC et\u00a0al (2022) The safe surgical margin in Ewing\u2019s sarcoma. Surg Oncol 41:101737","journal-title":"Surg Oncol"},{"issue":"1","key":"2579_CR8","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-025-06405-5","volume":"152","author":"SS Bielack","year":"2026","unstructured":"Bielack\u00a0SS et\u00a0al (2026) Undifferentiated pleomorphic sarcoma of bone (UPSB) treated in the German-speaking countries. A report of 132 unselected patients from the Cooperative Osteosarcoma Study Group (COSS). J\u00a0Cancer Res Clin Oncol 152(1):40","journal-title":"J Cancer Res Clin Oncol"},{"issue":"1","key":"2579_CR9","doi-asserted-by":"publisher","first-page":"566","DOI":"10.3390\/curroncol31010040","volume":"31","author":"S Tsukamoto","year":"2024","unstructured":"Tsukamoto\u00a0S et\u00a0al (2024) A Systematic Review of Adjuvant Chemotherapy in Localized Dedifferentiated Chondrosarcoma. Curr Oncol 31(1):566\u2013578","journal-title":"Curr Oncol"},{"issue":"6","key":"2579_CR10","doi-asserted-by":"publisher","first-page":"749","DOI":"10.3109\/17453674.2011.636668","volume":"82","author":"D Andreou","year":"2011","unstructured":"Andreou\u00a0D et\u00a0al (2011) Survival and prognostic factors in chondrosarcoma: results in 115 patients with long-term follow-up. Acta Orthop 82(6):749\u2013755","journal-title":"Acta Orthop"},{"issue":"9","key":"2579_CR11","doi-asserted-by":"publisher","first-page":"1412","DOI":"10.1016\/j.ejso.2018.05.033","volume":"44","author":"JD Stevenson","year":"2018","unstructured":"Stevenson\u00a0JD et\u00a0al (2018) The role of surgical margins in chondrosarcoma. Eur J Surg Oncol 44(9):1412\u20131418","journal-title":"Eur J Surg Oncol"},{"issue":"4","key":"2579_CR12","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s00432-008-0486-z","volume":"135","author":"A Streitburger","year":"2009","unstructured":"Streitburger\u00a0A et\u00a0al (2009) Grade I chondrosarcoma of bone: the Munster experience. J\u00a0Cancer Res Clin Oncol 135(4):543\u2013550","journal-title":"J Cancer Res Clin Oncol"},{"issue":"2","key":"2579_CR13","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1002\/jso.20628","volume":"96","author":"G Bacci","year":"2007","unstructured":"Bacci\u00a0G et\u00a0al (2007) Local recurrence and local control of non-metastatic osteosarcoma of the extremities: a 27-year experience in a single institution. J\u00a0Surg Oncol 96(2):118\u2013123","journal-title":"J Surg Oncol"},{"issue":"3","key":"2579_CR14","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1097\/CORR.0000000000000806","volume":"478","author":"LA Aponte-Tinao","year":"2020","unstructured":"Aponte-Tinao\u00a0LA et\u00a0al (2020) Do Massive Allograft Reconstructions for Tumors of the Femur and Tibia Survive 10 or More Years after Implantation? Clin Orthop Relat Res 478(3):517\u2013524","journal-title":"Clin Orthop Relat Res"},{"issue":"6","key":"2579_CR15","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.1097\/CORR.0000000000001639","volume":"479","author":"C Errani","year":"2021","unstructured":"Errani\u00a0C et\u00a0al (2021) Does the Addition of a\u00a0Vascularized Fibula Improve the Results of a\u00a0Massive Bone Allograft Alone for Intercalary Femur Reconstruction of Malignant Bone Tumors in Children? Clin Orthop Relat Res 479(6):1296\u20131308","journal-title":"Clin Orthop Relat Res"},{"key":"2579_CR16","doi-asserted-by":"crossref","unstructured":"Ozturk R et\u00a0al (2024) Uncemented Customized Hollow Stems in Tumor Endoprosthetic Replacement\u2011A Good Opportunity to Protect the Adjacent Joint in Children? J\u00a0Pers Med 14(9)","DOI":"10.3390\/jpm14090919"},{"issue":"1","key":"2579_CR17","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/s00402-020-03583-4","volume":"142","author":"A Streitburger","year":"2022","unstructured":"Streitburger\u00a0A et\u00a0al (2022) Reconstruction survival of segmental megaendoprostheses: a\u00a0retrospective analysis of 28\u00a0patients treated for intercalary bone defects after musculoskeletal tumor resections. Arch Orthop Trauma Surg 142(1):41\u201356","journal-title":"Arch Orthop Trauma Surg"},{"key":"2579_CR18","doi-asserted-by":"crossref","unstructured":"Guder WK et\u00a0al (2021) Highly Cancellous Titanium Alloy (TiAl(6)V(4)) Surfaces on Three-Dimensionally Printed, Custom-Made Intercalary Tibia Prostheses: Promising Short- to Intermediate-Term Results. J\u00a0Pers Med 11(5)","DOI":"10.3390\/jpm11050351"},{"issue":"1","key":"2579_CR19","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1245\/s10434-015-4852-1","volume":"23","author":"D Andreou","year":"2016","unstructured":"Andreou\u00a0D et\u00a0al (2016) Metastatic Potential of Grade\u00a0I Chondrosarcoma of Bone: Results of a\u00a0Multi-institutional Study. Ann Surg Oncol 23(1):120\u2013125","journal-title":"Ann Surg Oncol"},{"issue":"6","key":"2579_CR20","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1302\/0301-620X.98B6.37417","volume":"98-B","author":"RJ Grimer","year":"2016","unstructured":"Grimer\u00a0RJ et\u00a0al (2016) Very long-term outcomes after endoprosthetic replacement for malignant tumours of bone. Bone Joint J 98-B(6):857\u2013864","journal-title":"Bone Joint J"},{"issue":"3","key":"2579_CR21","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1007\/s11999-015-4644-8","volume":"475","author":"MP Bus","year":"2017","unstructured":"Bus\u00a0MP et\u00a0al (2017) What Are the Long-term Results of MUTARS((R)) Modular Endoprostheses for Reconstruction of Tumor Resection of the Distal Femur and Proximal Tibia? Clin Orthop Relat Res 475(3):708\u2013718","journal-title":"Clin Orthop Relat Res"},{"issue":"12","key":"2579_CR22","doi-asserted-by":"publisher","first-page":"1887","DOI":"10.1016\/j.bjps.2019.08.009","volume":"72","author":"A Ruiz-Moya","year":"2019","unstructured":"Ruiz-Moya\u00a0A et\u00a0al (2019) Pediatric extremity bone sarcoma reconstruction with the vascularized fibula flap: Observational study assessing long-term functional outcomes, complications, and survival. J\u00a0Plast Reconstr Aesthet Surg 72(12):1887\u20131899","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"7","key":"2579_CR23","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1016\/j.bjps.2020.02.030","volume":"73","author":"S Othman","year":"2020","unstructured":"Othman\u00a0S et\u00a0al (2020) Allograft Alone vs. Allograft with Intramedullary Vascularized Fibular Graft for Lower Extremity Bone Cancer: A Systematic Review and Meta-Analysis. J\u00a0Plast Reconstr Aesthet Surg 73(7):1221\u20131231","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"22","key":"2579_CR24","doi-asserted-by":"publisher","first-page":"2036","DOI":"10.2106\/JBJS.19.00380","volume":"101","author":"J Li","year":"2019","unstructured":"Li\u00a0J et\u00a0al (2019) Factors Influencing Osseous Union Following Surgical Treatment of Bone Tumors with Use of the Capanna Technique. J\u00a0Bone Joint Surg Am 101(22):2036\u20132043","journal-title":"J Bone Joint Surg Am"},{"issue":"6","key":"2579_CR25","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1007\/s00590-017-1998-5","volume":"27","author":"J Lesensky","year":"2017","unstructured":"Lesensky\u00a0J, Prince\u00a0DE (2017) Distraction osteogenesis reconstruction of large segmental bone defects after primary tumor resection: pitfalls and benefits. Eur J Orthop Surg Traumatol 27(6):715\u2013727","journal-title":"Eur J Orthop Surg Traumatol"},{"issue":"3","key":"2579_CR26","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/s00402-006-0123-8","volume":"126","author":"A Kapukaya","year":"2006","unstructured":"Kapukaya\u00a0A et\u00a0al (2006) Technique and complications of callus distraction in the treatment of bone tumors. Arch Orthop Trauma Surg 126(3):157\u2013163","journal-title":"Arch Orthop Trauma Surg"},{"issue":"5","key":"2579_CR27","doi-asserted-by":"publisher","first-page":"408","DOI":"10.2106\/JBJS.K.01446","volume":"95","author":"JC Bell","year":"2013","unstructured":"Bell\u00a0JC et\u00a0al (2013) Transfemoral amputations: the effect of residual limb length and orientation on gait analysis outcome measures. J\u00a0Bone Joint Surg Am 95(5):408\u2013414","journal-title":"J Bone Joint Surg Am"},{"issue":"2","key":"2579_CR28","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1053\/j.oto.2013.11.001","volume":"24","author":"NM Bernthal","year":"2014","unstructured":"Bernthal\u00a0NM et\u00a0al (2014) Rotationplasty: Beauty is in the Eye of the Beholder. Oper Tech Orthop 24(2):103\u2013110","journal-title":"Oper Tech Orthop"},{"issue":"7","key":"2579_CR29","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1007\/s00132-019-03721-w","volume":"48","author":"J Hardes","year":"2019","unstructured":"Hardes\u00a0J et\u00a0al (2019) Endoprostheses for stump formation after hip disarticulation. Orthopade 48(7):582\u2013587","journal-title":"Orthopade"}],"container-title":["Die Chirurgie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00104-026-02579-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00104-026-02579-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00104-026-02579-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T07:44:31Z","timestamp":1792568671000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00104-026-02579-x"}},"subtitle":["Lokaltherapeutische Abw\u00e4gungen hinsichtlich Resektionsausma\u00df und Rekonstruktion in einem multimodalen Therapiekonzept","Local therapeutic considerations with respect to extent of resection and reconstruction in a multimodal treatment concept"],"short-title":[],"issued":{"date-parts":[[2026,9,22]]},"references-count":29,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["2579"],"URL":"https:\/\/doi.org\/10.1007\/s00104-026-02579-x","relation":{},"ISSN":["2731-6971","2731-698X"],"issn-type":[{"value":"2731-6971","type":"print"},{"value":"2731-698X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,22]]},"assertion":[{"value":"18 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A.\u00a0Streitb\u00fcrger und J.\u00a0Hardes beziehen Vortragshonorare der Firma Implantcast. N.M.\u00a0Engel gibt an, dass kein Interessenkonflikt besteht.","order":1,"name":"Ethics","label":"Interessenkonflikt","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patient\/-innen zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern\/Vertreterinnen eine schriftliche Einwilligung vor.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}}]}}