{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T06:56:28Z","timestamp":1761807388740},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2008,1,23]],"date-time":"2008-01-23T00:00:00Z","timestamp":1201046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2008,1,23]],"date-time":"2008-01-23T00:00:00Z","timestamp":1201046400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hautarzt"],"published-print":{"date-parts":[[2008,3]]},"DOI":"10.1007\/s00105-007-1453-3","type":"journal-article","created":{"date-parts":[[2008,1,21]],"date-time":"2008-01-21T13:33:56Z","timestamp":1200922436000},"page":"220-229","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Orthop\u00e4disch-chirurgische Implantate und Allergien","Orthopedic surgical implants and allergies"],"prefix":"10.1007","volume":"59","author":[{"given":"P.","family":"Thomas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Schuh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Ring","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Thomsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,1,23]]},"reference":[{"key":"1453_CR1","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/s00132-004-0761-x","volume":"34","author":"Baur","year":"2005","unstructured":"Baur W, H\u00f6nle W, Schuh A (2005) Histopathologische Ver\u00e4nderungen im umgebenden Gewebe von revidierten Metall\/ Metallgleitpaarungen. Orthop\u00e4de 34: 225\u2013233","journal-title":"Orthop\u00e4de"},{"key":"1453_CR2","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1136\/bmj.4.5993.374","volume":"15","author":"Benson","year":"1975","unstructured":"Benson MK, Goodwin PG, Brostoff J (1975) Metal sensitivity in patients with joint replacement arthroplasties. Br Med J 15: 374\u2013375","journal-title":"Br Med J"},{"key":"1453_CR3","first-page":"202","volume":"16","author":"Brehler","year":"1990","unstructured":"Brehler R, Grabbe J, Eichelberg D (1990) Nickelallergie nach Plattenosteosynthese. Akt Dermatol 16: 202\u2013203","journal-title":"Akt Dermatol"},{"key":"1453_CR4","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/s00132-002-0411-0","volume":"32","author":"Breusch","year":"2003","unstructured":"Breusch SJ, K\u00fchn KD (2003) Knochenzemente auf der Basis von Polymethylmethacrylat. Orthop\u00e4de 32: 41\u201350","journal-title":"Orthop\u00e4de"},{"key":"1453_CR5","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1055\/s-2000-10172","volume":"138","author":"Brodner","year":"2000","unstructured":"Brodner W, Grohs JG, Bitzan P et al. (2000) Serum cobalt and serum chromium level in 2 patients with chronic renal failure after total hip prosthesis implantation with metal-metal gliding contact. Z Orthop Ihre Grenzgeb 138: 425\u2013429","journal-title":"Z Orthop Ihre Grenzgeb"},{"key":"1453_CR6","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3109\/17453678008990769","volume":"51","author":"Carlsson","year":"1980","unstructured":"Carlsson AS, Magnusson B, Moller H (1980) Metal sensitivity in patients with metal-to-plastic total hip arthroplasties. Acta Orthop Scand 51: 57\u201362","journal-title":"Acta Orthop Scand"},{"key":"1453_CR7","first-page":"62","volume":"69","author":"Carlsson","year":"1989","unstructured":"Carlsson A, Moller H (1989) Implantation of orthopaedic devices in patients with metal allergy. Acta Derm Venereol 69: 62\u201366","journal-title":"Acta Derm Venereol"},{"key":"1453_CR8","first-page":"476","volume":"38","author":"Christiansen","year":"1979","unstructured":"Christiansen K, Holmes K, Zilko PJ (1979) Metal sensitivity causing loosened joint prosthesis. Ann Rheum Dis 38: 476\u2013480","journal-title":"Ann Rheum Dis"},{"key":"1453_CR9","doi-asserted-by":"publisher","first-page":"245","DOI":"10.3109\/17453677708988763","volume":"48","author":"Cramers","year":"1977","unstructured":"Cramers M, Lucht U (1977) Metal sensitivity in patients treated for tibial fractures with plates of stainless steel. Acta Orthop Scand 48: 245\u2013249","journal-title":"Acta Orthop Scand"},{"key":"1453_CR10","doi-asserted-by":"publisher","first-page":"18","DOI":"10.2106\/JBJS.C.00949","volume":"87","author":"Davies","year":"2005","unstructured":"Davies AP, Willert HG, Campbell PA et al. (2005) An unusual lymphocytic perivascular infiltration in tissues around contemporary metal-on-metal joint replacements. J Bone Joint Surg Am 87: 18\u201327","journal-title":"J Bone Joint Surg Am"},{"key":"1453_CR11","doi-asserted-by":"crossref","first-page":"862","DOI":"10.2106\/00004623-197759070-00004","volume":"59","author":"Deutman","year":"1977","unstructured":"Deutman R, Mulder TJ, Brian R, Nater JP (1977) Metal sensitivity before and after total hip arthroplasty. J Bone Joint Surg Am 59: 862\u2013865","journal-title":"J Bone Joint Surg Am"},{"key":"1453_CR12","first-page":"1271","volume":"123","author":"Duchna","year":"1998","unstructured":"Duchna HW, Nowack U, Merget R et al. (1998) Prospektive Untersuchung zur Bedeutung der Kontaktsensibilisierung durch Metallimplantate. Zentralbl Chir 123: 1271\u20131276","journal-title":"Zentralbl Chir"},{"key":"1453_CR13","first-page":"9","volume":"19","author":"Ebert","year":"1993","unstructured":"Ebert B (1993) Metallallergisches Ekzem nach Osteosynthese. Akt Dermatol 19: 9\u201312","journal-title":"Akt Dermatol"},{"key":"1453_CR14","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1136\/bmj.4.5993.376","volume":"15","author":"Elves","year":"1975","unstructured":"Elves MW, Wilson JN, Scales JT, Kemp HB (1975) Incidence of metal sensitivity in patients with total joint replacements. Br Med J 15: 376\u2013378","journal-title":"Br Med J"},{"key":"1453_CR15","first-page":"676","volume":"36","author":"Farronato","year":"2002","unstructured":"Farronato G, Tirafili C, Alicino C, Santoro F (2002) Titanium appliances for allergic patients. J Clin Orthod 36: 676\u2013679","journal-title":"J Clin Orthod"},{"key":"1453_CR16","first-page":"220","volume":"52","author":"Foussereau","year":"1966","unstructured":"Foussereau J, Laugier P (1966) Allergic eczemas from metallic foreign bodies. Trans St Johns Hosp Dermatol Soc 52: 220\u2013225","journal-title":"Trans St Johns Hosp Dermatol Soc"},{"key":"1453_CR17","first-page":"91","volume":"6","author":"Goodman","year":"1996","unstructured":"Goodman SB (1996) Does the immune system play a role in loosening and osteolysis of total joint replacements? J Long Term Eff Med Implants 6: 91\u2013101","journal-title":"J Long Term Eff Med Implants"},{"key":"1453_CR18","first-page":"257","volume":"77","author":"Granchi","year":"2005","unstructured":"Granchi D, Cenni E, Trisolino G et al. (2005) Sensitivity to implant materials in patients undergoing total hip replacement. J Biomed Mater Res B Appl Biomater 77: 257\u2013264","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"1453_CR19","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1302\/0301-620X.78B4.0780546","volume":"78","author":"Haddad","year":"1996","unstructured":"Haddad FS, Cobb AG, Bentley G et al. (1996) Hypersensitivity in aseptic loosening of total hip replacements. The role of constituents of bone cement. J Bone Joint Surg Br 78: 546\u2013549","journal-title":"J Bone Joint Surg Br"},{"key":"1453_CR20","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1302\/0301-620X.83B3.9674","volume":"83","author":"Hallab","year":"2001","unstructured":"Hallab N, Merritt K, Jacobs JJ (2001) Metal sensitivity in patients with orthopaedic implants. J Bone Joint Surg Am 83: 428\u2013436","journal-title":"J Bone Joint Surg Am"},{"key":"1453_CR21","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/j.orthres.2004.09.001","volume":"23","author":"Hallab","year":"2005","unstructured":"Hallab NJ, Anderson S, Stafford T et al. (2005) Lymphocyte responses in patients with total hip arthroplasty. J Orthop Res 23: 384\u2013391","journal-title":"J Orthop Res"},{"key":"1453_CR22","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1111\/j.1600-0536.1999.tb06249.x","volume":"41","author":"Hayashi","year":"1999","unstructured":"Hayashi K, Kaneko H, Kawachi S, Saida T (1999) Allergic contact dermatitis and osteomyelitis due to sternal stainless steel wire. Contact Dermatitis 41: 115\u2013116","journal-title":"Contact Dermatitis"},{"key":"1453_CR23","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1007\/s00132-005-0849-y","volume":"34","author":"Holzwarth","year":"2005","unstructured":"Holzwarth U, Thomas P, Kachler W et al. (2005) Metallkundliche Differenzierung heutiger Kobaltbasis-Implantatlegierungen. Orthop\u00e4de 34: 1046\u20131051","journal-title":"Orthop\u00e4de"},{"key":"1453_CR24","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/BF00618442","volume":"94","author":"Jager","year":"1979","unstructured":"Jager M, Balda BR (1979) Loosening of a total hip prosthesis at contact allergy due to benzoyl peroxide. Arch Orthop Trauma Surg 94: 175\u2013178","journal-title":"Arch Orthop Trauma Surg"},{"key":"1453_CR25","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1054\/arth.2002.33571","volume":"17","author":"Kaplan","year":"2002","unstructured":"Kaplan K, Della Valle CJ, Haines K, Zuckerman JD (2002) Preoperative identification of a bone-cement allergy in a patient undergoing total knee arthroplasty. J Arthroplasty 17: 788\u2013791","journal-title":"J Arthroplasty"},{"key":"1453_CR26","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1034\/j.1600-0536.2001.4402096.x","volume":"44","author":"Kanerva","year":"2001","unstructured":"Kanerva L, Forstrom L (2001) Allergic nickel and chromate hand dermatitis induced by orthopaedic metal implant. Contact Dermatitis 44: 103\u2013104","journal-title":"Contact Dermatitis"},{"key":"1453_CR27","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/01.blo.0000150451.50452.da","volume":"430","author":"Konttinen","year":"2005","unstructured":"Konttinen YT, Zhao D, Beklen A et al. (2005) The microenvironment around total hip replacement prostheses. Clin Orthop 430: 28\u201338","journal-title":"Clin Orthop"},{"key":"1453_CR28","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1302\/0301-620X.78B1.0780018","volume":"78","author":"Kreibich","year":"1996","unstructured":"Kreibich DN, Moran CG, Delves HT et al. (1996) Systemic release of cobalt and chromium after uncemented total hip replacement. J Bone Joint Surg Br 78: 18\u201321","journal-title":"J Bone Joint Surg Br"},{"key":"1453_CR29","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1001\/archderm.117.9.554","volume":"117","author":"Kubba","year":"1981","unstructured":"Kubba R, Taylor JS, Marks KE (1981) Cutaneous complications of orthopedic implants. A two-year prospective study. Arch Dermatol 117: 554\u2013560","journal-title":"Arch Dermatol"},{"key":"1453_CR30","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1302\/0301-620X.73B1.1991768","volume":"73","author":"Lalor","year":"1991","unstructured":"Lalor PA, Revell PA, Gray AB et al. (1991) Sensitivity to titanium. A cause of implant failure? J Bone Joint Surg Br 73: 25\u201328","journal-title":"J Bone Joint Surg Br"},{"key":"1453_CR31","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/S0002-9610(98)00197-4","volume":"176","author":"Lhotka","year":"1998","unstructured":"Lhotka CG, Szekeres T, Fritzer-Szekeres M et al. (1998) Are allergic reactions to skin clips associated with delayed wound healing? Am J Surg 176: 320\u2013323","journal-title":"Am J Surg"},{"key":"1453_CR32","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1111\/j.0105-1873.2005.00494.x","volume":"52","author":"Liden","year":"2005","unstructured":"Liden C, Norberg K (2005) Nickel on the Swedish market. Follow-up after implementation of the Nickel Directive. Contact Dermatitis 52: 29\u201335","journal-title":"Contact Dermatitis"},{"key":"1453_CR33","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1097\/01.bor.0000198004.88568.96","volume":"18","author":"Looney","year":"2006","unstructured":"Looney RJ, Schwarz EM, Boyd A, O\u2019Keefe RJ (2006) Periprostethic osteolysis: an immunologist\u2019s update. Curr Opin Rheumatol 18: 80\u201387","journal-title":"Curr Opin Rheumatol"},{"key":"1453_CR34","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1007\/s00402-001-0382-3","volume":"122","author":"Maezawa","year":"2002","unstructured":"Maezawa K, Nozawa M, Hirose T et al. (2002) Cobalt and chromium concentrations in patients with metal-on-metal and other cementless total hip arthroplasty. Arch Orthop Trauma Surg 122: 283\u2013287","journal-title":"Arch Orthop Trauma Surg"},{"key":"1453_CR35","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1136\/bmj.4.5570.36","volume":"4","author":"McKenzie","year":"1967","unstructured":"McKenzie AW, Aitken CV, Ridsdill-Smith R (1967) Urticaria after insertion of Smith-Petersen Vitallium nail. Br Med J 4: 36","journal-title":"Br Med J"},{"key":"1453_CR36","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1365-4362.1981.tb00408.x","volume":"20","author":"Merritt","year":"1981","unstructured":"Merritt K, Brown SA (1981) Metal sensitivity reactions to orthopedic implants. Int J Dermatol 20: 89\u201394","journal-title":"Int J Dermatol"},{"key":"1453_CR37","first-page":"S233","volume":"Orthop","author":"Merritt","year":"1996","unstructured":"Merritt K, Brown SA (1996) Distribution of cobalt chromium wear and corrosion products and biologic reactions. Clin Orthop (Suppl) 329: S233\u2013S243","journal-title":"Clin"},{"key":"1453_CR38","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1097\/00003086-199605000-00009","volume":"326","author":"Merritt","year":"1996","unstructured":"Merritt K, Rodrigo JJ (1996) Immune response to synthetic materials. Sensitization of patients receiving orthopaedic implants. Clin Orthop 326: 71\u201379","journal-title":"Clin Orthop"},{"key":"1453_CR39","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1111\/j.1600-0536.1976.tb02986.x","volume":"2","author":"Munro-Ashman","year":"1976","unstructured":"Munro-Ashman D, Miller AJ (1976) Rejection of metal to metal prosthesis and skin sensitivity to cobalt. Contact Dermatitis 2: 65\u201367","journal-title":"Contact Dermatitis"},{"key":"1453_CR40","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1177\/014107688708000511","volume":"80","author":"Oakley","year":"1987","unstructured":"Oakley AM, Ive FA, Carr MM (1987) Skin clips are contraindicated when there is nickel allergy. J R Soc Med 80: 290\u2013291","journal-title":"J R Soc Med"},{"key":"1453_CR41","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.2106\/JBJS.D.02641","volume":"87","author":"Park","year":"2005","unstructured":"Park YS, Moon YW, Lim SJ et al. (2005) Early osteolysis following second-generation metal-on-metal hip replacement. J Bone Joint Surg Am 87: 1515\u20131521","journal-title":"J Bone Joint Surg Am"},{"key":"1453_CR42","first-page":"987","volume":"55","author":"Richter-Hintz","year":"2004","unstructured":"Richter-Hintz D, Rieker J, Rauch L, Homey Bl (2004) Prothesenunvertr\u00e4glichkeit bei Typ-IV-Sensibilisierung gegen Knochenzement. Hautarzt 55: 987\u2013989","journal-title":"Hautarzt"},{"key":"1453_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1006\/faat.1996.2279","volume":"36","author":"Rodgers","year":"1997","unstructured":"Rodgers K, Klykken P, Jacobs J et al. (1997) Immunotoxicity of medical devices. Symposium overview. Fundam Appl Toxicol 36: 1\u201314","journal-title":"Fundam Appl Toxicol"},{"key":"1453_CR44","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1302\/0301-620X.62B4.7430234","volume":"62","author":"Rooker","year":"1980","unstructured":"Rooker GD, Wilkinson JD (1980) Metal sensitivity in patients undergoing hip replacement. A prospective study. J Bone Joint Surg Br 62: 502\u2013505","journal-title":"J Bone Joint Surg Br"},{"key":"1453_CR45","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/BF02935627","volume":"14","author":"Santamaria","year":"1995","unstructured":"Santamaria Babi LF, Perez Soler MT, Hauser C, Blaser K (1995) Skin-homing T cells in human cutaneous allergic inflammation. Immunol Res 14: 317\u2013324","journal-title":"Immunol Res"},{"key":"1453_CR46","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1034\/j.1398-9995.2001.00086.x","volume":"56","author":"Sch\u00e4fer","year":"2001","unstructured":"Sch\u00e4fer T, Bohler E, Ruhdorfer S et al. (2001) Epidemiology of contact allergy in adults. Allergy 56: 1192\u20131196","journal-title":"Allergy"},{"key":"1453_CR47","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1081\/CLT-100102463","volume":"37","author":"Schaffer","year":"1999","unstructured":"Schaffer AW, Pilger A, Engelhardt C et al. (1999) Increased blood cobalt and chromium after total hip replacement. J Toxicol Clin Toxicol 37: 839\u2013844","journal-title":"J Toxicol Clin Toxicol"},{"key":"1453_CR48","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF03361311","volume":"13","author":"Schnuch","year":"2004","unstructured":"Schnuch A, Geier J, Lessmann H et al. (2004) Kontaktallergene im aktuellen Zeitverlauf. Allergo J 13: 57\u201369","journal-title":"Allergo J"},{"key":"1453_CR49","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1016\/j.jaci.2004.01.368","volume":"113","author":"Sch\u00f6berl","year":"2004","unstructured":"Sch\u00f6berl A, Summer B, Jakob K et al. (2004) Periimplantar cobalt specific DTH reaction in a patch test negative patient with failure of hip arthroplasty. J Allergy Clin Immunol 113: 250\u2013251","journal-title":"J Allergy Clin Immunol"},{"key":"1453_CR50","first-page":"727","volume":"33","author":"Schuh","year":"2004","unstructured":"Schuh A, Thomas P, Holzwarth U, Zeiler G (2004) Bilaterale umschriebene Osteolyse nach zementierter H\u00fcfttotalendoprothesenimplantation. Orthop\u00e4de 33: 727\u2013731","journal-title":"Orthop\u00e4de"},{"key":"1453_CR51","first-page":"1577","volume":"Techn","author":"Schuh","year":"2005","unstructured":"Schuh A, Thomas P, Kachler W et al. (2005) Characterisation of histologic sections of granulomas of revised total hip arthroplasties using a scanning electron micoscope (SEM). Biomed Techn (Berl) (Suppl) 50: 1577\u20131578","journal-title":"Biomed"},{"key":"1453_CR52","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1007\/s00132-005-0764-2","volume":"34","author":"Schuh","year":"2005","unstructured":"Schuh A, Thomas P, Kachler W et al. (2005) Das Allergiepotential von Implantatwerkstoffen auf Basis Titan. Orthop\u00e4de 34: 327\u2013333","journal-title":"Orthop\u00e4de"},{"key":"1453_CR53","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1055\/s-2006-949533","volume":"131","author":"Schuh","year":"2006","unstructured":"Schuh A, Thomas P, Holzwarth U et al. (2006) Allergie auf Knochenzementbestandteile nach Knieendoprothesenimplantation. Zentralbl Chir 131: 429\u2013431","journal-title":"Zentralbl Chir"},{"key":"1453_CR54","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1097\/00005131-200102000-00002","volume":"15","author":"Swiontkowski","year":"2001","unstructured":"Swiontkowski MF, Agel J, Schwappach J et al. (2001) Cutaneous metal sensitivity in patients with orthopaedic injuries. J Orthop Trauma 15: 86\u201389","journal-title":"J Orthop Trauma"},{"key":"1453_CR55","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1111\/j.1600-0536.1995.tb00551.x","volume":"33","author":"Tan","year":"1995","unstructured":"Tan M, Suzuki H (1995) Usefulness of titanium implants for systemic contact dermatitis due to orthopaedic prostheses. Contact Dermatitis 33: 202","journal-title":"Contact Dermatitis"},{"key":"1453_CR56","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/s004020000230","volume":"121","author":"Thewes","year":"2001","unstructured":"Thewes M, Kretschmer R, Gfesser M et al. (2001) Immunohistochemical characterization of the perivascular infiltrate cells in tissues adjacent to stainless steel implants compared with titanium implants. Arch Orthop Trauma Surg 121: 223\u2013226","journal-title":"Arch Orthop Trauma Surg"},{"key":"1453_CR57","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1034\/j.1398-9995.2000.00619.x","volume":"55","author":"Thomas","year":"2000","unstructured":"Thomas P, Thomas M, Summer B et al. (2000) Intolerance of osteosynthesis material: evidence of dichromate contact allergy with concomitant oligoklonal T-cell infiltrate and TH1-type cytokine expression in the peri-implantar tissue. Allergy 55: 969\u2013972","journal-title":"Allergy"},{"key":"1453_CR58","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1007\/s00132-002-0413-y","volume":"32","author":"Thomas","year":"2003","unstructured":"Thomas P (2003) Allergien durch Implantatwerkstoffe. Orthop\u00e4de 32: 60\u201364","journal-title":"Orthop\u00e4de"},{"key":"1453_CR59","first-page":"51","volume":"13","author":"Thomas","year":"2004","unstructured":"Thomas P, Barnstorf S, Rueff F et al. (2004) Kontaktallergie gegen Endoprothesenkomponenten als m\u00f6gliche Ursache einer Knieendoprothesen-Unvertr\u00e4glichkeit. Allergo J 13: 51","journal-title":"Allergo J"},{"key":"1453_CR60","first-page":"48","volume":"15","author":"Thomas","year":"2006","unstructured":"Thomas P, Oppel T, Maier S, Przybilla B (2006) Die Rolle von Knochenzementkomponenten bei der Unvertr\u00e4glichkeit von Knieendoprothesen. Allergo J 15: 48","journal-title":"Allergo J"},{"key":"1453_CR61","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1007\/s00132-006-0981-3","volume":"35","author":"Thomas","year":"2006","unstructured":"Thomas P, Schuh A, Summer B et al. (2006) Knochenzementallergie. Orthop\u00e4de 35: 956\u2013960","journal-title":"Orthop\u00e4de"},{"key":"1453_CR62","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1111\/j.0105-1873.2006.0775j.x","volume":"54","author":"Thomas","year":"2006","unstructured":"Thomas P, Gollwitzer H, Maier S, Rueff F (2006) Osteosynthesis associated contact dermatitis with unusual perpetuation of hyperreactivity in a nickel allergic patient. Contact Dermatitis 54: 222\u2013225","journal-title":"Contact Dermatitis"},{"key":"1453_CR63","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1111\/j.1600-0536.2006.00931.x","volume":"55","author":"Thomas","year":"2006","unstructured":"Thomas P, Bandl WD, Maier S et al. (2006) Hypersensitivity to titanium osteosynthesis with impaired fracture healing, eczema and T-cell hyperresponsiveness in vitro: case report and review of the literature. Contact Dermatitis 55: 199\u2013202","journal-title":"Contact Dermatitis"},{"key":"1453_CR64","doi-asserted-by":"crossref","unstructured":"Thomas P, Gabel M (2007) Persistierende Entz\u00fcndung nach Gro\u00dfzehenkorrekturoperation bei einer Patientin mit Nickelallergie: Manifestation einer \u00dcberempfindlichkeit gegen Metallpartikel? Fu\u00df Sprunggelenk (eingereicht)","DOI":"10.1016\/j.fuspru.2008.06.017"},{"key":"1453_CR65","unstructured":"Thomas P, Braathen LR, D\u00f6rig M et al. (2007) Increased metal sensitivity and periimplant T-lymphocytic inflammation in patients with failed metal-to-metal total hip replacement. J Bone Joint Surg (submitted)"},{"key":"1453_CR66","first-page":"1121","volume":"28","author":"Thomssen","year":"2001","unstructured":"Thomssen H, Hoffmann B, Schank M et al. (2001) Cobalt-specific T lymphocytes in synovial tissue after an allergic reaction to a cobalt alloy joint prosthesis. J Rheumatol 28: 1121\u20131128","journal-title":"J Rheumatol"},{"key":"1453_CR67","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1016\/j.jclinepi.2003.04.002","volume":"57","author":"Uter","year":"2004","unstructured":"Uter W, Ludwig A, Balda BR et al. (2004) The prevalence of contact allergy differed between population-based and clinic-based data. J Clin Epidemiol 57: 627\u2013632","journal-title":"J Clin Epidemiol"},{"key":"1453_CR68","doi-asserted-by":"crossref","unstructured":"Wetzel S, Thomas P (2004) Allergie gegen Implantatwerkstoffe. In: Plewig G, Kaudewitz P, Sander C (Hrsg) Fortschritte der praktischen Dermatologie und Venerologie. Springer, Berlin Heidelberg New York Tokyo, S\u00a0817\u2013818","DOI":"10.1007\/3-540-28691-8_137"},{"key":"1453_CR69","first-page":"165","volume":"9","author":"Willert","year":"2000","unstructured":"Willert HG, Buchhorn A, Fayyazi A, Lohmann CH (2000) Histopathologische Ver\u00e4nderungen bei Metall\/Metall-Gelenken geben Hinweise auf eine zellvermittelte \u00dcberempfindlichkeit. Osteologie 9: 165\u2013179","journal-title":"Osteologie"},{"key":"1453_CR70","doi-asserted-by":"publisher","first-page":"28","DOI":"10.2106\/JBJS.A.02039pp","volume":"87","author":"Willert","year":"2005","unstructured":"Willert HG, Buchhorn GH, Fayyazi A et al. (2005) Metal-on-metal bearings and hypersensitivity in patients with artificial hip joints. A clinical and histomorphological study. J Bone Joint Surg Am 87: 28\u201336","journal-title":"J Bone Joint Surg Am"},{"key":"1453_CR71","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1007\/s00105-005-1050-2","volume":"56","author":"Worm","year":"2005","unstructured":"Worm M, Brasch J, Geier J et al. (2005) Epikutantestung mit der DKG Standardreihe 2001\u20132004. Ergebnisse des IVDK. Hautarzt 56: 1114\u20131124","journal-title":"Hautarzt"},{"key":"1453_CR72","first-page":"52","volume":"42","author":"Yamauchi","year":"2000","unstructured":"Yamauchi R, Morita A, Tsuji T (2000) Pacemaker dermatitis from titanium. Contact Dermatitis 42: 52\u201353","journal-title":"Contact Dermatitis"}],"container-title":["Der Hautarzt"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-007-1453-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00105-007-1453-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-007-1453-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-007-1453-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:04:37Z","timestamp":1652659477000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00105-007-1453-3"}},"subtitle":["Gemeinsame Stellungnahme des Arbeitskreises Implantatallergie (AK\u00a020) der Deutschen Gesellschaft f\u00fcr Orthop\u00e4die und Orthop\u00e4dische Chirurgie (DGOOC), der Deutschen Kontaktallergie Gruppe (DKG) und der Deutschen Gesellschaft f\u00fcr Allergologie und Klinische Immunologie (DGAKI)","Joint statement by the Implant Allergy Working Group (AK 20) of the DGOOC (German Association of Orthopedics and Orthopedic Surgery), DKG (German Contact Dermatitis Research Group) and DGAKI (German Society for Allergology and Clinical Immunology)"],"short-title":[],"issued":{"date-parts":[[2008,1,23]]},"references-count":72,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["1453"],"URL":"https:\/\/doi.org\/10.1007\/s00105-007-1453-3","relation":{},"ISSN":["0017-8470","1432-1173"],"issn-type":[{"value":"0017-8470","type":"print"},{"value":"1432-1173","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1,23]]},"assertion":[{"value":"23 January 2008","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}