{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:14:28Z","timestamp":1762917268410},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hautarzt"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1007\/s00105-009-1909-8","type":"journal-article","created":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T15:18:42Z","timestamp":1270135122000},"page":"345-355","source":"Crossref","is-referenced-by-count":13,"title":["Management des Pyoderma gangraenosum"],"prefix":"10.1007","volume":"61","author":[{"given":"L.","family":"Tr\u00e9mezaygues","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Schmaltz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Vogt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Reichrath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,4,3]]},"reference":[{"key":"1909_CR1","doi-asserted-by":"crossref","unstructured":"Bennett ML, Jackson JM, Jorizzo JL et al (2000) Pyoderma gangrenosum. A comparison of typical and atypical forms with an emphasis on time to remission. Case review of 86 patients from 2 institutions. Medicine (Baltimore) 79:37\u201346","DOI":"10.1097\/00005792-200001000-00004"},{"key":"1909_CR2","first-page":"287","volume":"68","author":"Neal","year":"2001","unstructured":"Neal M, Blitz DPM, Rudikoff MD (2001) Pyoderma gangrenosum. Mount Sinai J Med 68:287\u2013297","journal-title":"Mount Sinai J Med"},{"key":"1909_CR3","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1001\/archderm.1930.01440160053009","volume":"22","author":"Brunsting","year":"1930","unstructured":"Brunsting LA, Goeckerman WH, O\u2019Leary PA (1930) Pyoderma gangrenosum: clinical and experimental observation in five cases occurring in adults. Arch Dermatol 22:655","journal-title":"Arch Dermatol"},{"key":"1909_CR4","unstructured":"M\u00fcnter KC (o J) Das Pyoderma gangraenosum \u2013 eine multidisziplin\u00e4re Herausforderung. Wundzentrum Hamburg."},{"key":"1909_CR5","doi-asserted-by":"crossref","unstructured":"Altmeyer P, Holzmann H, Bacharach-Buhles M, Buhles N (1986) Lexikon der Dermatologie. Springer, Berlin Heidelberg New York","DOI":"10.1007\/978-3-642-96900-3"},{"key":"1909_CR6","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1111\/j.1610-0387.2007.0328.x","volume":"5","author":"Hasselmann","year":"2007","unstructured":"Hasselmann DO, Bens G, Tilgen W, Reichrath J (2007) Pyoderma gangrenosum: clinical presentation and outcome in 18 cases and review of the literature. JDDG 5:560\u2013564","journal-title":"JDDG"},{"key":"1909_CR7","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1001\/archsurg.1994.01420310101019","volume":"129","author":"Cairns","year":"1994","unstructured":"Cairns BA, Herbst CA, Sartor BR et al (1994) Peristomal pyoderma gangrenosum and inflammatory bowel disease. Arch Surg 129(7):769\u2013772","journal-title":"Arch Surg"},{"key":"1909_CR8","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1001\/archderm.1957.01550150066007","volume":"75","author":"Perry","year":"1957","unstructured":"Perry HO, Brunsting LA (1957) Pyoderma gangrenosum: a clinical study of 19 cases. Arch Dermatol 75:380\u2013386","journal-title":"Arch Dermatol"},{"key":"1909_CR9","doi-asserted-by":"crossref","unstructured":"Fritsch P (1983) Dermatologie. Springer, Berlin Heidelberg New York","DOI":"10.1007\/978-3-642-96746-7"},{"key":"1909_CR10","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1111\/j.1572-0241.2003.07581.x","volume":"98","author":"Regueiro","year":"2003","unstructured":"Regueiro M, Valentine J, Plevy S et al (2003) Infliximab for treatment of pyoderma gangrenosum associated with inflammatory bowel disease. Am J Gastroenterol 98:1821\u20131826","journal-title":"Am J Gastroenterol"},{"key":"1909_CR11","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1097\/00042737-200208000-00021","volume":"14","author":"Romero-Gomez","year":"2002","unstructured":"Romero-Gomez M, Sanchez-Munoz D (2002) Infliximab induces remission of pyoderma gangrenosum. Eur J Gastroenterol Hepatol 14:907","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"1909_CR12","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1136\/gut.2005.074815","volume":"55","author":"Brooklyn","year":"2006","unstructured":"Brooklyn TN, Dunnill M, Shetty A et al (2006) Infliximab for the treatment of pyoderma gangrenosum: a randomized, double-blind, placebo controlled trial. Gut 55:505\u2013509","journal-title":"Gut"},{"key":"1909_CR13","doi-asserted-by":"crossref","first-page":"67","DOI":"10.2165\/00128071-200708020-00002","volume":"8","author":"Reguiai","year":"2007","unstructured":"Reguiai Z, Grange F (2007) The role of anti-tumor necrosis factor-alpha therapy in pyoderma gangraenosum associated with inflammatory bowel disease. Am J Clin Dermatol 8:67\u201377","journal-title":"Am J Clin Dermatol"},{"key":"1909_CR14","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1038\/ajg.2009.271","volume":"104","author":"Kawakami","year":"2009","unstructured":"Kawakami T, Yamasaki M, Soma Y (2009) Reduction of Interleukin-6, Interleukin-8, and Anti-phosphatidylserine-prothrombin complex antibody by granulocyte and monocyte adsorption apheresis in a patient with pyoderma gangraenosum and ulcerative colitis. Am J Gastroenterol 104:2363\u20132364","journal-title":"Am J Gastroenterol"},{"key":"1909_CR15","doi-asserted-by":"crossref","unstructured":"Braun-Falco O (1984) Dermatologie und Venerologie. Springer, Berlin Heidelberg","DOI":"10.1007\/978-3-662-00524-8"},{"key":"1909_CR16","first-page":"6","volume":"3","author":"Wines","year":"2001","unstructured":"Wines N, Wines M, Ryman W (2001) Understanding pyoderma gangrenosum: a review. MedGenMed 3(3):6","journal-title":"MedGenMed"},{"key":"1909_CR17","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1001\/archderm.1973.01620250060025","volume":"108","author":"Tay","year":"1973","unstructured":"Tay CH (1973) Pyoderma gangrenosum and leukemia. Arch Dermatol 108:580","journal-title":"Arch Dermatol"},{"key":"1909_CR18","doi-asserted-by":"crossref","unstructured":"Jacobs P, Palmer S, Gordon-Smith ES (1985) Pyoderma gangrenosum in myelodysplasia and acute leukemia. Post-Grad Med J 61:689","DOI":"10.1136\/pgmj.61.718.689"},{"key":"1909_CR19","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1159\/000249709","volume":"168","author":"Bundino","year":"1984","unstructured":"Bundino S, Zina AM (1984) Pyoderma gangrenosum associated with selective hereditary IgA deficiency. Dermatologica 168:230","journal-title":"Dermatologica"},{"key":"1909_CR20","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1034\/j.1600-0560.2003.00024.x","volume":"30","author":"Crowson","year":"2003","unstructured":"Crowson AN, Magro C, Mihm MC Jr (2003) Pyoderma gangrenosum: a review. J Cutan Pathol 30:97\u2013107","journal-title":"J Cutan Pathol"},{"key":"1909_CR21","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1001\/archderm.1984.01650430149026","volume":"120","author":"Powell","year":"1984","unstructured":"Powell FC, Schroeter AL, Su WPD, Perry HO (1984) Pyoderma gangrenosum and sarcoidosis. Arch Dermatol 120:959","journal-title":"Arch Dermatol"},{"key":"1909_CR22","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1001\/archderm.1986.01660170032014","volume":"122","author":"Schwartz","year":"1986","unstructured":"Schwartz BK, Clendenning WE, Blasik LG (1986) Pyoderma gangrenosum in a patient with HTLV-III antibody. Arch Dermatol 122:508","journal-title":"Arch Dermatol"},{"key":"1909_CR23","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1001\/archderm.1978.01640190049017","volume":"114","author":"O","year":"1978","unstructured":"O\u2019Loughlin S, Perry HO (1978) A diffuse pustular eruption associated with ulcerative colitis. Arch Dermatol 114(7):1061\u20131064","journal-title":"Arch Dermatol"},{"key":"1909_CR24","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1001\/archderm.1972.01620150083026","volume":"106","author":"Perry","year":"1972","unstructured":"Perry HO, Winkelmann RK (1972) Bullous pyoderma gangrenosum and leukemia. Arch Dermatol 106(6):901\u2013905","journal-title":"Arch Dermatol"},{"key":"1909_CR25","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S0190-9622(88)70074-2","volume":"18","author":"Wilson-Jones","year":"1988","unstructured":"Wilson-Jones E, Winkelmann RK (1988) Superficial granulomatous pyoderma: a localized vegetative form of pyoderma gangrenosum. J Am Acad Dermatol 18(3):511\u2013521","journal-title":"J Am Acad Dermatol"},{"key":"1909_CR26","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1067\/mjd.2000.103627","volume":"43","author":"Brown","year":"2000","unstructured":"Brown TS, Marshall GS, Callen JP (2000) Cavitating pulmonary Infiltrate in an adolescent with pyoderma gangrenosum: a rarely recognized extracutaneous manifestation of a neutrophilic dermatosis. J Am Acad Dermatol 43:108\u2013112","journal-title":"J Am Acad Dermatol"},{"key":"1909_CR27","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1016\/S0161-6420(02)01165-X","volume":"109","author":"Miserocchi","year":"2002","unstructured":"Miserocchi E, Modorati G, Foster CS, Brancato R (2002) Ocular and extracutaneous involvement in pyoderma gangrenosum. Ophthalmology 109:1941\u20131943","journal-title":"Ophthalmology"},{"key":"1909_CR28","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.jaad.2004.10.006","volume":"53","author":"Reichrath","year":"2005","unstructured":"Reichrath J, Bens G, Bonowitz A, Tilgen W (2005) Treatment recommendations for pyoderma gangrenosum: an evidence-based review of the literature based on more than 350 patients. J Am Acad Dermatol 53(2):273\u2013283","journal-title":"J Am Acad Dermatol"},{"key":"1909_CR29","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/S0161-6420(02)01966-8","volume":"110","author":"Rose","year":"2003","unstructured":"Rose GE, Barnes EA, Uddin JM (2003) Pyoderma gangrenosum of the ocular adnexa: a rare condition with characteristic clinical appearances. Ophthalmology 110:801\u2013805","journal-title":"Ophthalmology"},{"key":"1909_CR30","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1046\/j.1365-2133.2001.04035.x","volume":"144","author":"Setterfield","year":"2001","unstructured":"Setterfield JF, Shirlaw PJ, Challacombe SJ, Black MM (2001) Pyoderma gangrenosum associated with severe oropharyngeal involvement and IgA paraproteinaemia. Br J Dermatol 144:393\u2013396","journal-title":"Br J Dermatol"},{"key":"1909_CR31","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1097\/01.ju.0000057721.16493.21","volume":"169","author":"Gonzalgo","year":"2003","unstructured":"Gonzalgo ML, Lacerda DA de, De Marzo AM, Chan DY (2003) Persistent purulent drainage from the glans penis: atypical presentation of pyoderma gangrenosum. J Urol 169:1793\u20131794","journal-title":"J Urol"},{"key":"1909_CR32","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1111\/j.1365-2133.1997.tb01568.x","volume":"137","author":"Von","year":"1997","unstructured":"Von den Driesch P (1997) Pyoderma gangrenosum: a report of 44 cases with follow-up. Br J Dermatol 137(6):1000\u20131005","journal-title":"Br J Dermatol"},{"key":"1909_CR33","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1111\/j.1365-4632.2004.02128.x","volume":"43","author":"Su","year":"2004","unstructured":"Su WP, Davis MD, Weenig RH et al (2004) Pyoderma gangrenosum: clinicopathologic correlation and proposed diagnostic criteria. Int J Dermatol 43(11):790\u2013800","journal-title":"Int J Dermatol"},{"key":"1909_CR34","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1046\/j.1365-4362.2002.01329.x","volume":"41","author":"Mlika","year":"2002","unstructured":"Mlika RB, Riahi I, Fenniche S et al (2002) Pyoderma gangrenosum: a report of 21 cases. Int J Dermatol 41:65\u201368","journal-title":"Int J Dermatol"},{"key":"1909_CR35","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/S0190-9622(96)90285-6","volume":"34","author":"Chow","year":"1996","unstructured":"Chow RK, Ho VC (1996) Treatment of pyoderma gangrenosum. J Am Acad Dermatol 34:1047\u20131060","journal-title":"J Am Acad Dermatol"},{"key":"1909_CR36","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1001\/archderm.1992.01680180054005","volume":"128","author":"Matis","year":"1992","unstructured":"Matis WL, Ellis CN, Griffiths CE, Lazarus GS (1992) Treatment of pyoderma gangrenosum with cyclosporine. Arch Dermatol 128:1060\u20131064","journal-title":"Arch Dermatol"},{"key":"1909_CR37","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/00000441-200105000-00004","volume":"321","author":"Moraes","year":"2001","unstructured":"Moraes M, Russo G (2001) Thalidomide and its dermatologic uses. Am J Med Sci 321:321\u2013326","journal-title":"Am J Med Sci"},{"key":"1909_CR38","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1046\/j.1468-3083.2000.00019.x","volume":"14","author":"Wollina","year":"2000","unstructured":"Wollina U, Karamfilov T (2000) Treatment of recalcitrant ulcers in pyoderma gangrenosum with mycophenolate mofetil and autologous keratinocyte transplantation on a hyaluronic acid matrix. J Eur Acad Dermatol Venereol 14:187\u2013190","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"1909_CR39","first-page":"3328","volume":"23","author":"Abu-Elmagd","year":"1991","unstructured":"Abu-Elmagd K, Jegasothy BV, Ackerman CD et al (1991) Efficacy of FK 506 in the treatment of recalcitrant pyoderma gangrenosum. Transplant Proc 23:3328\u20133329","journal-title":"Transplant Proc"},{"key":"1909_CR40","doi-asserted-by":"crossref","first-page":"595","DOI":"10.7326\/0003-4819-119-7_Part_1-199310010-00008","volume":"119","author":"Abu-Elmagd","year":"1993","unstructured":"Abu-Elmagd K, Van Thiel DH, Jegasothy BV et al (1993) Resolution of severe pyoderma gangrenosum in a patient with streaking leukocyte factor disease after treatment with tacrolimus (FK 506). Ann Intern Med 119:595\u2013598","journal-title":"Ann Intern Med"},{"key":"1909_CR41","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1067\/mjd.2003.172","volume":"48","author":"Dobson","year":"2003","unstructured":"Dobson CM, Parslew RA, Evans S (2003) Superficial granulomatous pyoderma treated with intravenous immunoglobulin. J Am Acad Dermatol 48:456\u2013460","journal-title":"J Am Acad Dermatol"},{"key":"1909_CR42","first-page":"29","volume":"Interne","author":"Gerard","year":"1988","unstructured":"Gerard A, Schooneman F, Voiriot P et al (1988) Pyoderma gangrenosum: treatment with plasma exchange (4 cases). Ann Med Interne (Paris) 139(Suppl1):29\u201331","journal-title":"Ann Med"},{"key":"1909_CR43","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1159\/000065843","volume":"205","author":"Wenzel","year":"2002","unstructured":"Wenzel J, Gerdsen R, Phillipp-Dormston W et al (2002) Topical treatment of pyoderma gangrenosum. Dermatology 205:221\u2013223","journal-title":"Dermatology"},{"key":"1909_CR44","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/j.1365-2230.1992.tb00254.x","volume":"17","author":"Tsele","year":"1992","unstructured":"Tsele E, Yu RC, Chu AC (1992) Pyoderma gangrenosum \u2013 response to topical nitrogen mustard. Clin Exp Dermatol 17:437\u2013440","journal-title":"Clin Exp Dermatol"},{"key":"1909_CR45","first-page":"262","volume":"51","author":"Sanders","year":"1993","unstructured":"Sanders CJ, Hulsmans RF (1993) Successful treatment of pyoderma gangrenosum with topical 5-aminosalicylic acid. Cutis 51:262\u2013264","journal-title":"Cutis"},{"key":"1909_CR46","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1159\/000245686","volume":"195","author":"Vereecken","year":"1997","unstructured":"Vereecken P, Wautrecht JC, De Dobbeleer G, Heenen M (1997) A case of pyoderma gangrenosum stabilized with lymecycline, topical benzoyl peroxide and treated by autograft. Dermatology 195:50\u201351","journal-title":"Dermatology"},{"key":"1909_CR47","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1067\/mjd.2002.120597","volume":"47","author":"Kanekura","year":"2002","unstructured":"Kanekura T, Maruyama I, Kanzaki T (2002) Granulocyte and monocyte adsorption apheresis for pyoderma gangrenosum. J Am Acad Dermatol 47:320\u2013321","journal-title":"J Am Acad Dermatol"},{"key":"1909_CR48","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/S0190-9622(96)90076-6","volume":"34","author":"Smith","year":"1996","unstructured":"Smith JB, Shenefelt PD, Soto O, Valeriano J (1996) Pyoderma gangrenosum in a patient with cryoglobulinemia and hepatitis C successfully treated with interferon alfa. J Am Acad Dermatol 34:901\u2013903","journal-title":"J Am Acad Dermatol"}],"container-title":["Der Hautarzt"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-009-1909-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00105-009-1909-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-009-1909-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T22:32:05Z","timestamp":1558996325000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00105-009-1909-8"}},"subtitle":["Update zu Klinik, Diagnose und Therapie"],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":48,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["1909"],"URL":"https:\/\/doi.org\/10.1007\/s00105-009-1909-8","relation":{},"ISSN":["0017-8470","1432-1173"],"issn-type":[{"value":"0017-8470","type":"print"},{"value":"1432-1173","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4]]}}}