{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T04:19:34Z","timestamp":1779941974894,"version":"3.53.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2017,3,9]],"date-time":"2017-03-09T00:00:00Z","timestamp":1489017600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hautarzt"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1007\/s00105-017-3959-7","type":"journal-article","created":{"date-parts":[[2017,3,9]],"date-time":"2017-03-09T15:35:38Z","timestamp":1489073738000},"page":"431-436","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Physiologie der Kopfhaut","Physiology of the scalp"],"prefix":"10.1007","volume":"68","author":[{"given":"R.","family":"Rukwied","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,3,9]]},"reference":[{"issue":"2","key":"3959_CR1","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/head.12984","volume":"57","author":"J Baron","year":"2016","unstructured":"Baron J, Ruiz M, Palacios-Cena M et al (2016) Differences in topographical pressure pain sensitivity maps of the scalp between patients with migraine and healthy controls. Headache 57(2):226\u2013235","journal-title":"Headache"},{"key":"3959_CR2","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/j.1365-2133.2012.11070.x","volume":"167","author":"GA Saif Bin","year":"2012","unstructured":"Bin Saif GA, Alajroush A, Mcmichael A et\u00a0al (2012) Aberrant C nerve fibre function of the healthy scalp. Br J Dermatol 167:485\u2013489","journal-title":"Br. J. Dermatol."},{"key":"3959_CR3","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1007\/s004030050189","volume":"289","author":"TE Damsgaard","year":"1997","unstructured":"Damsgaard TE, Olesen AB, Sorensen FB et\u00a0al (1997) Mast cells and atopic dermatitis. Stereological quantification of mast cells in atopic dermatitis and normal human skin. Arch Dermatol Res 289:256\u2013260","journal-title":"Arch. Dermatol. Res."},{"key":"3959_CR4","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1365-2230.1994.tb01248.x","volume":"19","author":"DJ Eedy","year":"1994","unstructured":"Eedy DJ, Shaw C, Johnston CF et al (1994) The regional distribution of neuropeptides in human skin as assessed by radioimmunoassay and high-performance liquid chromatography. Clin Exp Dermatol 19:463\u2013472","journal-title":"Clin Exp Dermatol"},{"key":"3959_CR5","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1080\/08990220400012414","volume":"21","author":"G Essick","year":"2004","unstructured":"Essick G, Guest S, Martinez E et al (2004) Site-dependent and subject-related variations in perioral thermal sensitivity. Somatosens Mot Res 21:159\u2013175","journal-title":"Somatosens Mot Res"},{"key":"3959_CR6","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.pain.2006.09.017","volume":"128","author":"E Fusayasu","year":"2007","unstructured":"Fusayasu E, Kowa H, Takeshima T et al (2007) Increased plasma substance P and CGRP levels, and high ACE activity in migraineurs during headache-free periods. Pain 128:209\u2013214","journal-title":"Pain"},{"key":"3959_CR7","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s00403-002-0323-1","volume":"294","author":"CR Harding","year":"2002","unstructured":"Harding CR, Moore AE, Rogers JS et\u00a0al (2002) Dandruff: a\u00a0condition characterized by decreased levels of intercellular lipids in scalp stratum corneum and impaired barrier function. Arch Dermatol Res 294:221\u2013230","journal-title":"Arch. Dermatol. Res."},{"key":"3959_CR8","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0733-8635(05)70391-0","volume":"14","author":"MK Hordinsky","year":"1996","unstructured":"Hordinsky MK, Ericson ME (1996) Relationship between follicular nerve supply and alopecia. Dermatol Clin 14:651\u2013660","journal-title":"Dermatol Clin"},{"key":"3959_CR9","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1080\/08990220020002051","volume":"17","author":"A James","year":"2000","unstructured":"James A, Essick GK, Kelly DG et al (2000) Frequency and site-dependent variations in vibration detection thresholds on the face. Somatosens Mot Res 17:349\u2013360","journal-title":"Somatosens Mot Res"},{"key":"3959_CR10","first-page":"43","volume":"4","author":"O Johansson","year":"1999","unstructured":"Johansson O, Wang L, Hilliges M et\u00a0al (1999) Intraepidermal nerves in human skin: PGP 9.5 immunohistochemistry with special reference to the nerve density in skin from different body regions. J\u00a0Peripher Nerv Syst 4:43\u201352","journal-title":"J. Peripher. Nerv. Syst."},{"key":"3959_CR11","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1159\/000337933","volume":"25","author":"N Luther","year":"2012","unstructured":"Luther N, Darvin ME, Sterry W et\u00a0al (2012) Ethnic differences in skin physiology, hair follicle morphology and follicular penetration. Skin Pharmacol Physiol 25:182\u2013191","journal-title":"Skin Pharmacol Physiol"},{"key":"3959_CR12","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.pain.2010.07.026","volume":"151","author":"W Magerl","year":"2010","unstructured":"Magerl W, Krumova EK, Baron R et\u00a0al (2010) Reference data for quantitative sensory testing (QST): refined stratification for age and a\u00a0novel method for statistical comparison of group data. Pain 151:598\u2013605","journal-title":"Pain"},{"key":"3959_CR13","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3109\/08990220.2011.602764","volume":"28","author":"A Mehrabyan","year":"2011","unstructured":"Mehrabyan A, Guest S, Essick G et\u00a0al (2011) Tactile and thermal detection thresholds of the scalp skin. Somatosens Mot Res 28:31\u201347","journal-title":"Somatosens Mot Res"},{"key":"3959_CR14","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1111\/j.1526-4610.2012.02212.x","volume":"52","author":"K Messlinger","year":"2012","unstructured":"Messlinger K, Lennerz JK, Eberhardt M et\u00a0al (2012) CGRP and NO in the trigeminal system: mechanisms and role in headache generation. Headache 52:1411\u20131427","journal-title":"Headache"},{"key":"3959_CR15","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/j.1600-0536.2007.01288.x","volume":"58","author":"L Misery","year":"2008","unstructured":"Misery L, Sibaud V, Ambronati M et\u00a0al (2008) Sensitive scalp: does this condition exist? An epidemiological study. Contact Derm 58:234\u2013238","journal-title":"Contact Derm."},{"key":"3959_CR16","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1067\/mjd.2002.120461","volume":"47","author":"R Rukwied","year":"2002","unstructured":"Rukwied R, Zeck S, Schmelz M et\u00a0al (2002) Sensitivity of human scalp skin to pruritic stimuli investigated by intradermal microdialysis in vivo. J\u00a0Am Acad Dermatol 47:245\u2013250","journal-title":"J. Am. Acad. Dermatol."},{"key":"3959_CR17","first-page":"221","volume":"10","author":"JC Szepietowski","year":"2002","unstructured":"Szepietowski JC, Reich A, Wisnicka B (2002) Itching in patients suffering from psoriasis. Acta Dermatovenerol Croat 10:221\u2013226","journal-title":"Acta Dermatovenerol Croat"},{"key":"3959_CR18","doi-asserted-by":"crossref","unstructured":"Tillmann BN (2016) Atlas der Anatomie. Berlin, Heidelberg: Springer","DOI":"10.1007\/978-3-662-49288-8"},{"key":"3959_CR19","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1177\/0333102416653233","volume":"36","author":"T Voss","year":"2016","unstructured":"Voss T, Lipton RB, Dodick DW et al (2016) A phase IIb randomized, double-blind, placebo-controlled trial of ubrogepant for the acute treatment of migraine. Cephalalgia 36:887\u2013898","journal-title":"Cephalalgia"},{"key":"3959_CR20","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1046\/j.1523-1747.2000.00142.x","volume":"115","author":"C Weidner","year":"2000","unstructured":"Weidner C, Klede M, Rukwied R et al (2000) Acute effects of substance P and calcitonin gene-related peptide in human skin \u2013 a microdialysis study. J Invest Dermatol 115:1015\u20131020","journal-title":"J. Invest. Dermatol."},{"key":"3959_CR21","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.0105-1873.2004.00439.x","volume":"51","author":"H Zhai","year":"2004","unstructured":"Zhai H, Fautz R, Fuchs A et\u00a0al (2004) Human scalp irritation compared to that of the arm and back. Contact Derm 51:196\u2013200","journal-title":"Contact Derm."}],"container-title":["Der Hautarzt"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00105-017-3959-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-017-3959-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-017-3959-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T14:41:10Z","timestamp":1568904070000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00105-017-3959-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,9]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["3959"],"URL":"https:\/\/doi.org\/10.1007\/s00105-017-3959-7","relation":{},"ISSN":["0017-8470","1432-1173"],"issn-type":[{"value":"0017-8470","type":"print"},{"value":"1432-1173","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,9]]}}}