{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T00:44:06Z","timestamp":1740185046063,"version":"3.37.3"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T00:00:00Z","timestamp":1649980800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T00:00:00Z","timestamp":1649980800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001661","name":"Ruprecht-Karls-Universit\u00e4t Heidelberg","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001661","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dermatologie"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Charakteristische Hautver\u00e4nderungen f\u00fchren zu der Diagnose eines Pseudoxanthoma elasticum (PXE). Das PXE repr\u00e4sentiert eine ektope Mineralisationsst\u00f6rung, welche prim\u00e4r die Haut, die Augen und das arterielle Gef\u00e4\u00dfsystem betrifft. Eine fr\u00fchzeitige Diagnosestellung ist entscheidend f\u00fcr die rechtzeitige Behandlung von extrakutanen Komplikationen. Wir verdeutlichen die Lotsenfunktion der Dermatologen und Dermatologinnen anhand einer Serie von vier unabh\u00e4ngigen F\u00e4llen eines PXE mit pathognomonischen Hautver\u00e4nderungen und einem weiten Spektrum an systemischen Komplikationen.<\/jats:p>","DOI":"10.1007\/s00105-022-04987-6","type":"journal-article","created":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T20:24:05Z","timestamp":1650054245000},"page":"804-808","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pseudoxanthoma elasticum: Die Lotsenfunktion des Dermatologen","Pseudoxanthoma elasticum: the dermatologist as a\u00a0guide"],"prefix":"10.1007","volume":"73","author":[{"given":"Jana","family":"Burghaus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Schneiderbauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdinand","family":"Toberer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,4,15]]},"reference":[{"key":"4987_CR1","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1016\/j.jid.2018.12.017","volume":"139","author":"J Huang","year":"2019","unstructured":"Huang\u00a0J, Snook\u00a0AE, Uitto\u00a0J et al (2019) Adenovirus-mediated ABCC6 gene therapy for heritable ectopic mineralization disorders. 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F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patienten zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern eine schriftliche Einwilligung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}