{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,22]],"date-time":"2025-06-22T22:21:17Z","timestamp":1750630877205},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T00:00:00Z","timestamp":1677024000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T00:00:00Z","timestamp":1677024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum Halle (Saale)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dermatologie"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Es ist seit Langem bekannt, dass chronisch entz\u00fcndliche Systemerkrankungen wie die Psoriasis ein hohes Risiko f\u00fcr die Entwicklung von Komorbidit\u00e4t bieten. Im klinischen Alltag ist es deshalb von besonderer Bedeutung, Patient:innen zu identifizieren, die ein individuell erh\u00f6htes Risikoprofil bieten. Bei Menschen mit Psoriasis konnten in epidemiologischen Studien in Abh\u00e4ngigkeit von Krankheitsdauer und -schwere die Komorbidit\u00e4tsmuster \u201emetabolisches Syndrom\u201c, \u201ekardiovaskul\u00e4re Komorbidit\u00e4t\u201c und \u201epsychische Erkrankungen\u201c als besonders relevant identifiziert werden. In der allt\u00e4glichen Versorgung von Menschen mit Psoriasis in der dermatologischen Praxis haben sich der Einsatz einer interdisziplin\u00e4r inhaltlich abgestimmten Checkliste f\u00fcr die Risikoanalyse und die Bahnung einer professionellen Anschlussversorgung bew\u00e4hrt. Auf der Basis einer existierenden Checkliste wurden die Inhalte von einer interdisziplin\u00e4ren Expertengruppe kritisch bewertet, und eine leitlinienorientierte Aktualisierung wurde vorgenommen. Der nun vorgelegte Analysebogen stellt nach Auffassung der Autoren ein praktikables, sachbezogen fokussiertes und inhaltlich aktualisiertes Werkzeug f\u00fcr die Risikoermittlung von Komorbidit\u00e4t bei Patient:innen mit mittelschwerer bis schwerer Psoriasis dar.<\/jats:p>","DOI":"10.1007\/s00105-023-05116-7","type":"journal-article","created":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T13:03:11Z","timestamp":1677070991000},"page":"350-355","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Handlungsempfehlungen zur individuellen Risikoermittlung von Komorbidit\u00e4t bei erwachsenen Patienten mit Psoriasis","Recommendations for individual comorbidity risk assessment in adult patients with psoriasis"],"prefix":"10.1007","volume":"74","author":[{"given":"Johannes","family":"Wohlrab","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"K\u00f6rber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Adler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Bl\u00fcher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Zirlik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sascha","family":"Gerdes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,2,22]]},"reference":[{"key":"5116_CR1","doi-asserted-by":"publisher","first-page":"375","DOI":"10.4103\/ijdvl.IJDVL_114_19","volume":"86","author":"P Aguayo-Carreras","year":"2020","unstructured":"Aguayo-Carreras\u00a0P, Ruiz-Carrascosa\u00a0JC, Molina-Leyva\u00a0A (2020) Type D personality is associated with poor quality of life, social performance, and psychological impairment in patients with moderate to severe psoriasis: a cross-sectional study of 130\u00a0patients. Indian J Dermatol Venereol Leprol 86:375\u2013381","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"5116_CR2","doi-asserted-by":"publisher","first-page":"1640","DOI":"10.1161\/CIRCULATIONAHA.109.192644","volume":"120","author":"KG Alberti","year":"2009","unstructured":"Alberti\u00a0KG, Eckel\u00a0RH, Grundy\u00a0SM et\u00a0al (2009) Harmonizing the metabolic syndrome: a\u00a0joint interim statement of the international diabetes federation task force on epidemiology and prevention; national heart, lung, and blood institute; American heart association; world heart federation; international atherosclerosis society; and international association for the study of obesity. Circulation 120:1640\u20131645","journal-title":"Circulation"},{"key":"5116_CR3","unstructured":"Suchtforschungsverbund Baden-W\u00fcrttemberg AUDIT-C-Fragebogen. https:\/\/www.bundesaerztekammer.de\/fileadmin\/user_upload\/downloads\/AlkAUDITCFragebogen.pdf. Zugegriffen: 5. Okt. 2022"},{"key":"5116_CR4","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/s12902-021-00716-7","volume":"21","author":"P Bagheri","year":"2021","unstructured":"Bagheri\u00a0P, Khalili\u00a0D, Seif\u00a0M et\u00a0al (2021) Dynamic behavior of metabolic syndrome progression: a\u00a0comprehensive systematic review on recent discoveries. BMC Endocr Disord 21:54","journal-title":"BMC Endocr Disord"},{"issue":"2","key":"5116_CR5","doi-asserted-by":"publisher","first-page":"S21","DOI":"10.1038\/ijo.2008.31","volume":"32","author":"CM Ballantyne","year":"2008","unstructured":"Ballantyne\u00a0CM, Hoogeveen\u00a0RC, Mcneill\u00a0AM et\u00a0al (2008) Metabolic syndrome risk for cardiovascular disease and diabetes in the ARIC study. Int J Obes (Lond) 32(2):S21\u201324","journal-title":"Int J Obes (Lond)"},{"key":"5116_CR6","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1111\/j.1365-2133.2007.08190.x","volume":"157","author":"S Boehncke","year":"2007","unstructured":"Boehncke\u00a0S, Thaci\u00a0D, Beschmann\u00a0H et\u00a0al (2007) Psoriasis patients show signs of insulin resistance. Br J Dermatol 157:1249\u20131251","journal-title":"Br J Dermatol"},{"key":"5116_CR7","doi-asserted-by":"publisher","first-page":"579","DOI":"10.3389\/fimmu.2018.00579","volume":"9","author":"WH Boehncke","year":"2018","unstructured":"Boehncke\u00a0WH (2018) Systemic inflammation and cardiovascular comorbidity in psoriasis patients: causes and consequences. Front Immunol 9:579","journal-title":"Front Immunol"},{"key":"5116_CR8","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1111\/j.1600-0625.2011.01261.x","volume":"20","author":"WH Boehncke","year":"2011","unstructured":"Boehncke\u00a0WH, Boehncke\u00a0S, Tobin\u00a0AM et\u00a0al (2011) The \u2018psoriatic march\u2019: a\u00a0concept of how severe psoriasis may drive cardiovascular comorbidity. Exp Dermatol 20:303\u2013307","journal-title":"Exp Dermatol"},{"key":"5116_CR9","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1038\/sj.jhh.1001858","volume":"19","author":"CJ Boos","year":"2005","unstructured":"Boos\u00a0CJ, Lip\u00a0GY (2005) Elevated high-sensitive C\u2011reactive protein, large arterial stiffness and atherosclerosis: a\u00a0relationship between inflammation and hypertension? J\u00a0Hum Hypertens 19:511\u2013513","journal-title":"J Hum Hypertens"},{"key":"5116_CR10","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1089\/met.2019.0092","volume":"18","author":"KP Botelho","year":"2020","unstructured":"Botelho\u00a0KP, de Andrade Pontes\u00a0MA, Rodrigues\u00a0CEM et al (2020) Prevalence of metabolic syndrome among patients with psoriasis treated with TNF inhibitors and the effects of anti-TNF therapy on their lipid profile: a prospective cohort study. Metab Syndr Relat Disord 18:154\u2013160","journal-title":"Metab Syndr Relat Disord"},{"key":"5116_CR11","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1055\/a-1661-0020","volume":"41","author":"H Bugger","year":"2021","unstructured":"Bugger\u00a0H, Zirlik\u00a0A (2021) Anti-inflammatory strategies in atherosclerosis. Hamostaseologie 41:433\u2013442","journal-title":"Hamostaseologie"},{"key":"5116_CR12","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1001\/archinte.158.16.1789","volume":"158","author":"K Bush","year":"1998","unstructured":"Bush\u00a0K, Kivlahan\u00a0DR, Mcdonell\u00a0MB et al (1998) The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory care quality improvement project (ACQUIP). Alcohol use disorders identification test. Arch Intern Med 158:1789\u20131795","journal-title":"Arch Intern Med"},{"key":"5116_CR13","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s13555-020-00466-9","volume":"11","author":"G Chen","year":"2021","unstructured":"Chen\u00a0G, Chen\u00a0ZM, Fan\u00a0XY et al (2021) Gut-brain-skin axis in psoriasis: a review. Dermatol Ther (Heidelb) 11:25\u201338","journal-title":"Dermatol Ther (Heidelb)"},{"key":"5116_CR14","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1177\/039463201002300128","volume":"23","author":"D Colombo","year":"2010","unstructured":"Colombo\u00a0D, Caputo\u00a0A, Finzi\u00a0A et\u00a0al (2010) Evolution of and risk factors for psychological distress in patients with psoriasis: the PSYCHAE study. Int J Immunopathol Pharmacol 23:297\u2013306","journal-title":"Int J Immunopathol Pharmacol"},{"key":"5116_CR15","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1111\/j.1468-3083.2012.04690.x","volume":"28","author":"AM D\u2019erme","year":"2014","unstructured":"D\u2019erme\u00a0AM, Zanieri\u00a0F, Campolmi\u00a0E et al (2014) Therapeutic implications of adding the psychotropic drug escitalopram in the treatment of patients suffering from moderate-severe psoriasis and psychiatric comorbidity: a\u00a0retrospective study. J\u00a0Eur Acad Dermatol Venereol 28:246\u2013249","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"5116_CR16","doi-asserted-by":"publisher","first-page":"473","DOI":"10.15288\/jsa.2006.67.473","volume":"67","author":"I Dybek","year":"2006","unstructured":"Dybek\u00a0I, Bischof\u00a0G, Grothues\u00a0J et\u00a0al (2006) The reliability and validity of the alcohol use disorders identification test (AUDIT) in a\u00a0German general practice population sample. J\u00a0Stud Alcohol 67:473\u2013481","journal-title":"J Stud Alcohol"},{"key":"5116_CR17","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1016\/j.jaad.2018.11.058","volume":"80","author":"CA Elmets","year":"2019","unstructured":"Elmets\u00a0CA, Leonardi\u00a0CL, Davis\u00a0DMR et al (2019) Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities. J\u00a0Am Acad Dermatol 80:1073\u20131113","journal-title":"J Am Acad Dermatol"},{"key":"5116_CR18","doi-asserted-by":"publisher","first-page":"e71","DOI":"10.1192\/j.eurpsy.2021.2249","volume":"64","author":"M Fabrazzo","year":"2021","unstructured":"Fabrazzo\u00a0M, Cipolla\u00a0S, Signoriello\u00a0S et\u00a0al (2021) A systematic review on shared biological mechanisms of depression and anxiety in comorbidity with psoriasis, atopic dermatitis, and hidradenitis suppurativa. Eur Psychiatry 64:e71","journal-title":"Eur Psychiatry"},{"key":"5116_CR19","doi-asserted-by":"publisher","first-page":"2282","DOI":"10.1016\/j.ijcard.2013.01.197","volume":"168","author":"M Gaeta","year":"2013","unstructured":"Gaeta\u00a0M, Castelvecchio\u00a0S, Ricci\u00a0C et al (2013) Role of psoriasis as independent predictor of cardiovascular disease: a\u00a0meta-regression analysis. Int J Cardiol 168:2282\u20132288","journal-title":"Int J Cardiol"},{"key":"5116_CR20","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1111\/bjd.16031","volume":"178","author":"E Galili","year":"2018","unstructured":"Galili\u00a0E, Barzilai\u00a0A, Shreberk-Hassidim\u00a0R et al (2018) Neuropsychiatric comorbidity among adolescents with psoriasis. Br J Dermatol 178:910\u2013916","journal-title":"Br J Dermatol"},{"key":"5116_CR21","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1007\/s00105-016-3805-3","volume":"67","author":"S Gerdes","year":"2016","unstructured":"Gerdes\u00a0S, Mrowietz\u00a0U, Boehncke\u00a0WH (2016) Comorbidity in psoriasis. Hautarzt 67:438\u2013444","journal-title":"Hautarzt"},{"key":"5116_CR22","first-page":"1115","volume":"18","author":"S Gerdes","year":"2020","unstructured":"Gerdes\u00a0S, Wilsmann-Theis\u00a0D, Celis\u00a0D et al (2020) Two questions may be enough\u2014screening for depression in patients with psoriasis: a\u00a0multicenter study. J\u00a0Dtsch Dermatol Ges 18:1115\u20131125","journal-title":"J Dtsch Dermatol Ges"},{"key":"5116_CR23","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1038\/nrneph.2017.51","volume":"13","author":"A Gistera","year":"2017","unstructured":"Gistera\u00a0A, Hansson\u00a0GK (2017) The immunology of atherosclerosis. Nat Rev Nephrol 13:368\u2013380","journal-title":"Nat Rev Nephrol"},{"key":"5116_CR24","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.ad.2016.05.009","volume":"107","author":"E Gonzalez-Parra","year":"2016","unstructured":"Gonzalez-Parra\u00a0E, Dauden\u00a0E, Carrascosa\u00a0JM et al (2016) Kidney disease and psoriasis. A new comorbidity? Actas Dermosifiliogr 107:823\u2013829","journal-title":"Actas Dermosifiliogr"},{"key":"5116_CR25","doi-asserted-by":"publisher","first-page":"4992","DOI":"10.1016\/j.ijcard.2013.07.127","volume":"168","author":"WJ Gu","year":"2013","unstructured":"Gu\u00a0WJ, Weng\u00a0CL, Zhao\u00a0YT et al (2013) Psoriasis and risk of cardiovascular disease: a\u00a0meta-analysis of cohort studies. Int J Cardiol 168:4992\u20134996","journal-title":"Int J Cardiol"},{"key":"5116_CR26","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1111\/bjd.13788","volume":"175","author":"HJ Hunter","year":"2016","unstructured":"Hunter\u00a0HJ, Hinz\u00a0R, Gerhard\u00a0A et al (2016) Brain inflammation and psoriasis: a\u00a0[(11) C]-(R)-PK11195 positron emission tomography study. Br J Dermatol 175:1082\u20131084","journal-title":"Br J Dermatol"},{"key":"5116_CR27","doi-asserted-by":"publisher","first-page":"683","DOI":"10.2337\/diacare.24.4.683","volume":"24","author":"B Isomaa","year":"2001","unstructured":"Isomaa\u00a0B, Almgren\u00a0P, Tuomi\u00a0T et\u00a0al (2001) Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 24:683\u2013689","journal-title":"Diabetes Care"},{"issue":"18","key":"5116_CR28","doi-asserted-by":"publisher","first-page":"4347","DOI":"10.3390\/ijms20184347","volume":"20","author":"K Kamiya","year":"2019","unstructured":"Kamiya\u00a0K, Kishimoto\u00a0M, Sugai\u00a0J et\u00a0al (2019) Risk factors for the development of psoriasis. Int J Mol Sci 20(18):4347. https:\/\/doi.org\/10.3390\/ijms20184347","journal-title":"Int J Mol Sci"},{"key":"5116_CR29","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.metabol.2019.07.001","volume":"99","author":"HN Kim","year":"2019","unstructured":"Kim\u00a0HN, Han\u00a0K, Park\u00a0YG et al (2019) Metabolic syndrome is associated with an increased risk of psoriasis: a nationwide population-based study. Metabolism 99:19\u201324","journal-title":"Metabolism"},{"key":"5116_CR30","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1161\/01.ATV.0000164044.42910.6b","volume":"25","author":"JA Kim","year":"2005","unstructured":"Kim\u00a0JA, Koh\u00a0KK, Quon\u00a0MJ (2005) The union of vascular and metabolic actions of insulin in sickness and in health. Arterioscler Thromb Vasc Biol 25:889\u2013891","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"5116_CR31","doi-asserted-by":"publisher","first-page":"1888","DOI":"10.1161\/CIRCULATIONAHA.105.563213","volume":"113","author":"JA Kim","year":"2006","unstructured":"Kim\u00a0JA, Montagnani\u00a0M, Koh\u00a0KK et\u00a0al (2006) Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 113:1888\u20131904","journal-title":"Circulation"},{"key":"5116_CR32","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1016\/j.jaad.2008.01.006","volume":"58","author":"AB Kimball","year":"2008","unstructured":"Kimball\u00a0AB, Gladman\u00a0D, Gelfand\u00a0JM et\u00a0al (2008) National psoriasis foundation clinical consensus on psoriasis comorbidities and recommendations for screening. J\u00a0Am Acad Dermatol 58:1031\u20131042","journal-title":"J Am Acad Dermatol"},{"issue":"21","key":"5116_CR33","doi-asserted-by":"publisher","first-page":"8406","DOI":"10.3390\/ijms21218406","volume":"21","author":"E Komiya","year":"2020","unstructured":"Komiya\u00a0E, Tominaga\u00a0M, Kamata\u00a0Y et\u00a0al (2020) Molecular and cellular mechanisms of itch in psoriasis. Int J Mol Sci 21(21):8406. https:\/\/doi.org\/10.3390\/ijms21218406","journal-title":"Int J Mol Sci"},{"key":"5116_CR34","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1016\/j.jaad.2017.08.034","volume":"77","author":"L Kwa","year":"2017","unstructured":"Kwa\u00a0L, Kwa\u00a0MC, Silverberg\u00a0JI (2017) Cardiovascular comorbidities of pediatric psoriasis among hospitalized children in the United States. J\u00a0Am Acad Dermatol 77:1023\u20131029","journal-title":"J Am Acad Dermatol"},{"key":"5116_CR35","doi-asserted-by":"publisher","first-page":"2709","DOI":"10.1001\/jama.288.21.2709","volume":"288","author":"HM Lakka","year":"2002","unstructured":"Lakka\u00a0HM, Laaksonen\u00a0DE, Lakka\u00a0TA et al (2002) The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 288:2709\u20132716","journal-title":"JAMA"},{"issue":"8","key":"5116_CR36","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1177\/10547738211065105","volume":"31","author":"A Lee","year":"2022","unstructured":"Lee\u00a0A, Park\u00a0J (2022) Diagnostic test accuracy of the beck depression inventory for detecting major depression in adolescents: a systematic review and meta-analysis. Clin Nurs Res 31(8):1481\u20131490. https:\/\/doi.org\/10.1177\/10547738211065105","journal-title":"Clin Nurs Res"},{"key":"5116_CR37","doi-asserted-by":"publisher","first-page":"24043","DOI":"10.1038\/s41598-021-03174-2","volume":"11","author":"HJ Lee","year":"2021","unstructured":"Lee\u00a0HJ, Han\u00a0KD, Park\u00a0HE et al (2021) Changes in metabolic syndrome and risk of psoriasis: a\u00a0nationwide population-based study. Sci Rep 11:24043","journal-title":"Sci Rep"},{"key":"5116_CR38","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.clindermatol.2019.01.011","volume":"37","author":"DJ Lewis","year":"2019","unstructured":"Lewis\u00a0DJ, Chan\u00a0WH, Hinojosa\u00a0T et\u00a0al (2019) Mechanisms of microbial pathogenesis and the role of the skin microbiome in psoriasis: a review. Clin Dermatol 37:160\u2013166","journal-title":"Clin Dermatol"},{"key":"5116_CR39","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1038\/s41586-021-03392-8","volume":"592","author":"P Libby","year":"2021","unstructured":"Libby\u00a0P (2021) The changing landscape of atherosclerosis. Nature 592:524\u2013533","journal-title":"Nature"},{"key":"5116_CR40","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1038\/nature05663","volume":"445","author":"MA Lowes","year":"2007","unstructured":"Lowes\u00a0MA, Bowcock\u00a0AM, Krueger\u00a0JG (2007) Pathogenesis and therapy of psoriasis. Nature 445:866\u2013873","journal-title":"Nature"},{"issue":"4","key":"5116_CR41","doi-asserted-by":"publisher","first-page":"796","DOI":"10.3390\/cells9040796","volume":"9","author":"AM Martins","year":"2020","unstructured":"Martins\u00a0AM, Ascenso\u00a0A, Ribeiro\u00a0HM et al (2020) The brain-skin connection and the pathogenesis of psoriasis: a review with a\u00a0focus on the serotonergic system. Cells 9(4):796. https:\/\/doi.org\/10.3390\/cells9040796","journal-title":"Cells"},{"key":"5116_CR42","doi-asserted-by":"publisher","first-page":"e14292","DOI":"10.1111\/dth.14292","volume":"33","author":"VP Matiushenko","year":"2020","unstructured":"Matiushenko\u00a0VP, Kutasevych\u00a0YF, Havryliuk\u00a0OA et\u00a0al (2020) Effectiveness of psychopharmacotherapy in psoriasis patients with associated anxiety and depression. Dermatol Ther 33:e14292","journal-title":"Dermatol Ther"},{"key":"5116_CR43","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/S0092-8674(00)80721-7","volume":"97","author":"MF Mcdermott","year":"1999","unstructured":"Mcdermott\u00a0MF, Aksentijevich\u00a0I, Galon\u00a0J et\u00a0al (1999) Germline mutations in the extracellular domains of the 55\u202fkDa TNF receptor, TNFR1, define a\u00a0family of dominantly inherited autoinflammatory syndromes. Cell 97:133\u2013144","journal-title":"Cell"},{"key":"5116_CR44","doi-asserted-by":"publisher","first-page":"e297","DOI":"10.1371\/journal.pmed.0030297","volume":"3","author":"D Mcgonagle","year":"2006","unstructured":"Mcgonagle\u00a0D, Mcdermott\u00a0MF (2006) A proposed classification of the immunological diseases. PLoS Med 3:e297","journal-title":"PLoS Med"},{"key":"5116_CR45","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1001\/archdermatol.2011.119","volume":"147","author":"NN Mehta","year":"2011","unstructured":"Mehta\u00a0NN, Yu\u00a0Y, Saboury\u00a0B et al (2011) Systemic and vascular inflammation in patients with moderate to severe psoriasis as measured by [18F]-fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET\/CT): a\u00a0pilot study. Arch Dermatol 147:1031\u20131039","journal-title":"Arch Dermatol"},{"key":"5116_CR46","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1046\/j.1463-1326.2000.00092.x","volume":"2","author":"M Montagnani","year":"2000","unstructured":"Montagnani\u00a0M, Quon\u00a0MJ (2000) Insulin action in vascular endothelium: potential mechanisms linking insulin resistance with hypertension. Diabetes Obes Metab 2:285\u2013292","journal-title":"Diabetes Obes Metab"},{"key":"5116_CR47","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/s00403-017-1748-x","volume":"309","author":"H Mysliwiec","year":"2017","unstructured":"Mysliwiec\u00a0H, Baran\u00a0A, Harasim-Symbor\u00a0E et al (2017) Serum fatty acid profile in psoriasis and its comorbidity. Arch Dermatol Res 309:371\u2013380","journal-title":"Arch Dermatol Res"},{"key":"5116_CR48","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1016\/j.jaad.2006.08.040","volume":"55","author":"AL Neimann","year":"2006","unstructured":"Neimann\u00a0AL, Shin\u00a0DB, Wang\u00a0X et\u00a0al (2006) Prevalence of cardiovascular risk factors in patients with psoriasis. J\u00a0Am Acad Dermatol 55:829\u2013835","journal-title":"J Am Acad Dermatol"},{"key":"5116_CR49","doi-asserted-by":"publisher","first-page":"287","DOI":"10.6065\/apem.2040166.083","volume":"25","author":"CA Nogueira-De-Almeida","year":"2020","unstructured":"Nogueira-De-Almeida\u00a0CA (2020) Metabolic syndrome definition in adolescents should incorporate insulin resistance. Ann Pediatr Endocrinol Metab 25:287\u2013288","journal-title":"Ann Pediatr Endocrinol Metab"},{"key":"5116_CR50","unstructured":"Nvl-005\u202fA-R\u2011N (2017) S3-Leitlinie (Nationale Versorgungsleitlinie). https:\/\/www.leitlinien.de\/themen\/depression. Zugegriffen: 05. Okt. 2022"},{"key":"5116_CR51","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1001\/jamadermatol.2017.0499","volume":"153","author":"E Osier","year":"2017","unstructured":"Osier\u00a0E, Wang\u00a0AS, Tollefson\u00a0MM et\u00a0al (2017) Pediatric psoriasis comorbidity screening guidelines. JAMA Dermatol 153:698\u2013704","journal-title":"JAMA Dermatol"},{"key":"5116_CR52","first-page":"674","volume":"13","author":"MA Radtke","year":"2015","unstructured":"Radtke\u00a0MA, Mrowietz\u00a0U, Feuerhahn\u00a0J et\u00a0al (2015) Early detection of comorbidity in psoriasis: recommendations of the national conference on healthcare in psoriasis. J\u00a0Dtsch Dermatol Ges 13:674\u2013690","journal-title":"J Dtsch Dermatol Ges"},{"key":"5116_CR53","doi-asserted-by":"publisher","first-page":"1767","DOI":"10.3899\/jrheum.141112","volume":"42","author":"C Roubille","year":"2015","unstructured":"Roubille\u00a0C, Richer\u00a0V, Starnino\u00a0T et al (2015) Evidence-based recommendations for the management of comorbidities in rheumatoid arthritis, psoriasis, and psoriatic arthritis: expert opinion of the Canadian dermatology-rheumatology comorbidity initiative. J\u00a0Rheumatol 42:1767\u20131780","journal-title":"J Rheumatol"},{"key":"5116_CR54","doi-asserted-by":"publisher","first-page":"31","DOI":"10.5455\/medarh.2021.75.31-34","volume":"75","author":"EM Salihbegovic","year":"2021","unstructured":"Salihbegovic\u00a0EM, Kurtalic\u00a0S, Omerkic\u00a0E (2021) Comorbidity in men with psoriasis. Med Arch 75:31\u201334","journal-title":"Med Arch"},{"issue":"6","key":"5116_CR55","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1684\/ejd.2021.4146","volume":"31","author":"MC Schielein","year":"2021","unstructured":"Schielein\u00a0MC, Tizek\u00a0L, Knobloch\u00a0L et al (2021) Psoriasis and addiction: assessing mental health based on a cross-sectional study in Germany. Eur J Dermatol 31(6):722\u2013729. https:\/\/doi.org\/10.1684\/ejd.2021.4146","journal-title":"Eur J Dermatol"},{"issue":"6","key":"5116_CR56","doi-asserted-by":"publisher","first-page":"1818","DOI":"10.3390\/jcm9061818","volume":"9","author":"MC Schielein","year":"2020","unstructured":"Schielein\u00a0MC, Tizek\u00a0L, Schuster\u00a0B et\u00a0al (2020) Always Online? Internet addiction and social impairment in psoriasis across Germany. J\u00a0Clin Med 9(6):1818","journal-title":"J Clin Med"},{"key":"5116_CR57","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1089\/met.2020.0076","volume":"18","author":"A Serbis","year":"2020","unstructured":"Serbis\u00a0A, Giapros\u00a0V, Galli-Tsinopoulou\u00a0A et al (2020) Metabolic syndrome in children and adolescents: is there a\u00a0universally accepted definition? Does it matter? Metab Syndr Relat Disord 18:462\u2013470","journal-title":"Metab Syndr Relat Disord"},{"key":"5116_CR58","doi-asserted-by":"publisher","first-page":"233","DOI":"10.20882\/adicciones.990","volume":"31","author":"JS Sim\u00f3n Grima","year":"2019","unstructured":"Sim\u00f3n Grima\u00a0JS, Estrada-Marcen\u00a0N, Montero-Marin\u00a0J (2019) Exercise addiction measure through the exercise addiction inventory (EAI) and health in habitual exercisers. A systematic review and meta-analysis. Adicciones 31:233\u2013249","journal-title":"Adicciones"},{"key":"5116_CR59","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1007\/s00403-020-02087-w","volume":"313","author":"P Singh","year":"2021","unstructured":"Singh\u00a0P, Silverberg\u00a0JI (2021) Screening for cardiovascular comorbidity in United States outpatients with psoriasis, hidradenitis, and atopic dermatitis. Arch Dermatol Res 313:163\u2013171","journal-title":"Arch Dermatol Res"},{"key":"5116_CR60","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1111\/j.1365-2133.2008.08628.x","volume":"159","author":"B Strober","year":"2008","unstructured":"Strober\u00a0B, Teller\u00a0C, Yamauchi\u00a0P et al (2008) Effects of etanercept on C\u2011reactive protein levels in psoriasis and psoriatic arthritis. Br J Dermatol 159:322\u2013330","journal-title":"Br J Dermatol"},{"key":"5116_CR61","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.jaad.2016.07.064","volume":"76","author":"J Takeshita","year":"2017","unstructured":"Takeshita\u00a0J, Grewal\u00a0S, Langan\u00a0SM et\u00a0al (2017) Psoriasis and comorbid diseases: epidemiology. J\u00a0Am Acad Dermatol 76:377\u2013390","journal-title":"J Am Acad Dermatol"},{"key":"5116_CR62","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.jaad.2016.07.065","volume":"76","author":"J Takeshita","year":"2017","unstructured":"Takeshita\u00a0J, Grewal\u00a0S, Langan\u00a0SM et\u00a0al (2017) Psoriasis and comorbid diseases: implications for management. J\u00a0Am Acad Dermatol 76:393\u2013403","journal-title":"J Am Acad Dermatol"},{"key":"5116_CR63","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1530\/EJE-21-0238","volume":"185","author":"A Tropeano","year":"2021","unstructured":"Tropeano\u00a0A, Corica\u00a0D, Pomi\u00a0LA et\u00a0al (2021) The metabolic syndrome in pediatrics: do we have a\u00a0reliable definition? A systematic review. Eur J Endocrinol 185:265\u2013278","journal-title":"Eur J Endocrinol"},{"key":"5116_CR64","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.1111\/jdv.15651","volume":"33","author":"D Tzur Bitan","year":"2019","unstructured":"Tzur Bitan\u00a0D, Krieger\u00a0I, Comaneshter\u00a0D et al (2019) The association between the socioeconomic status and anxiety-depression comorbidity in patients with psoriasis: a\u00a0nationwide population-based study. J\u00a0Eur Acad Dermatol Venereol 33:1555\u20131561","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"5116_CR65","first-page":"3453","volume":"18","author":"S Uysal","year":"2014","unstructured":"Uysal\u00a0S, Yilmaz\u00a0FM, Karatoprak\u00a0K et al (2014) The levels of serum pentraxin3, CRP, fetuin\u2011A, and insulin in patients with psoriasis. Eur Rev Med Pharmacol Sci 18:3453\u20133458","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"5116_CR66","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1016\/j.jid.2020.07.012","volume":"141","author":"D Verma","year":"2021","unstructured":"Verma\u00a0D, Fekri\u00a0SZ, Sigurdardottir\u00a0G et\u00a0al (2021) Enhanced inflammasome activity in patients with psoriasis promotes systemic inflammation. J\u00a0Invest Dermatol 141:586\u2013595.e5","journal-title":"J Invest Dermatol"},{"key":"5116_CR67","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.6061\/clinics\/2013(09)15","volume":"68","author":"YP Wang","year":"2013","unstructured":"Wang\u00a0YP, Gorenstein\u00a0C (2013) Assessment of depression in medical patients: a\u00a0systematic review of the utility of the Beck depression inventory-II. Clinics (Sao Paulo) 68:1274\u20131287","journal-title":"Clinics (Sao Paulo)"},{"key":"5116_CR68","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1590\/1516-4446-2012-1048","volume":"35","author":"YP Wang","year":"2013","unstructured":"Wang\u00a0YP, Gorenstein\u00a0C (2013) Psychometric properties of the Beck depression inventory-II: a\u00a0comprehensive review. Braz J Psychiatry 35:416\u2013431","journal-title":"Braz J Psychiatry"},{"key":"5116_CR69","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1046\/j.1525-1497.1997.00076.x","volume":"12","author":"MA Whooley","year":"1997","unstructured":"Whooley\u00a0MA, Avins\u00a0AL, Miranda\u00a0J et al (1997) Case-finding instruments for depression. Two questions are as good as many. J\u00a0Gen Intern Med 12:439\u2013445","journal-title":"J Gen Intern Med"},{"key":"5116_CR70","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1007\/s00403-013-1318-9","volume":"305","author":"J Wohlrab","year":"2013","unstructured":"Wohlrab\u00a0J, Fiedler\u00a0G, Gerdes\u00a0S et\u00a0al (2013) Recommendations for detection of individual risk for comorbidities in patients with psoriasis. Arch Dermatol Res 305:91\u201398","journal-title":"Arch Dermatol Res"},{"key":"5116_CR71","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1080\/09546634.2017.1395800","volume":"29","author":"JJ Wu","year":"2018","unstructured":"Wu\u00a0JJ, Feldman\u00a0SR, Koo\u00a0J et\u00a0al (2018) Epidemiology of mental health comorbidity in psoriasis. J\u00a0Dermatolog Treat 29:487\u2013495","journal-title":"J Dermatolog Treat"},{"key":"5116_CR72","doi-asserted-by":"publisher","first-page":"295","DOI":"10.5551\/jat.12.295","volume":"12","author":"P Zimmet","year":"2005","unstructured":"Zimmet\u00a0P, Magliano\u00a0D, Matsuzawa\u00a0Y et\u00a0al (2005) The metabolic syndrome: a\u00a0global public health problem and a\u00a0new definition. J\u00a0Atheroscler Thromb 12:295\u2013300","journal-title":"J Atheroscler Thromb"}],"container-title":["Die Dermatologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-023-05116-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00105-023-05116-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-023-05116-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T01:23:20Z","timestamp":1683768200000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00105-023-05116-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,22]]},"references-count":72,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["5116"],"URL":"https:\/\/doi.org\/10.1007\/s00105-023-05116-7","relation":{},"ISSN":["2731-7005","2731-7013"],"issn-type":[{"value":"2731-7005","type":"print"},{"value":"2731-7013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,22]]},"assertion":[{"value":"20 January 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 February 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"Das Manuskript widerspiegelt die Arbeitsergebnisse einer Expertengruppe, die auf Veranlassung der Fa. Almirall in einem Beratungsboard die Inhalte erarbeitet und im Umlaufverfahren das Manuskript erstellt hat. Das Projekt wurde vollumf\u00e4nglich von der Fa. Almirall finanziert. Es wird ausdr\u00fccklich best\u00e4tigt, dass der Sponsor keinen Einfluss auf die erarbeiteten Inhalte genommen hat. Folgende Autoren geben an, in den letzten 5\u00a0Jahren Honorare f\u00fcr Beratung und\/oder Vortr\u00e4ge und\/oder Sponsoring f\u00fcr wissenschaftliche Projekte und\/oder klinische Studien von folgenden, im thematischen Zusammenhang relevanten Firmen erhalten zu haben: J.\u00a0Wohlrab \u2013\u00a0AbbVie, Almirall, Biogen, BMS, Boehringer Ingelheim, Celltrion, Galderma, GSK, Hexal, Janssen-Cilag, Leo, Lilly, MSD, Mylan, Novartis, Pfizer und Regeneron. A.\u00a0K\u00f6rber\u00a0\u2013 MSD, Pfizer, Biogen-Idec, AbbVie, Novartis, LEO-Pharma, Janssen-Cilag, Celgene, Lilly, Almirall, Hexal, Beiersdorf, BMS, Sanofi, UCB. G.\u00a0Adler \u2013\u00a0Almirall. M.\u00a0Bl\u00fcher\u00a0\u2013 Almirall, Amgen, AstraZeneca, Bayer, Boehringer-Ingelheim, Daiichi Sankyo, Lilly, Novartis, Novo Nordisk, Pfizer, Sanofi. A.\u00a0Zirlik \u2013\u00a0Almirall, Amgen, AstraZeneca, Bayer Health Care, Boehringer Ingelheim, Bristol Meyers Squibb, Daiichi Sankyo, Novartis, Pfizer, Sanofi Aventis. S.\u00a0Gerdes\u00a0\u2013 AbbVie, Affibody AB, Almirall, Amgen, Biogen Idec, Bioskin, Bristol-Myers Squibb, Boehringer Ingelheim, Celgene, Dermira, Eli Lilly, Foamix, Forward Pharma, Galderma, Hexal AG, Incyte Inc., Janssen-Cilag, Johnson & Johnson, Klinge Pharma, Leo Pharma, Medac, MSD, Neubourg Skin Care GmbH, Novartis, Pfizer, Sandoz Biopharmaceuticals, UCB Pharma.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}