{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:37:21Z","timestamp":1791506241458,"version":"4.3.4"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:00:00Z","timestamp":1682467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:00:00Z","timestamp":1682467200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum Hamburg-Eppendorf (UKE)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dermatologie"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n                <jats:title>Hintergrund<\/jats:title>\n                <jats:p>Der Pikosekundenlaser geh\u00f6rt zu den j\u00fcngsten in der Dermatologie genutzten Lasersystemen. Urspr\u00fcnglich wurde er zur Optimierung von T\u00e4towierungsentfernungen entwickelt, Fortschritte in dieser Technologie erweiterten das Indikationsspektrum des Pikosekundenlasers jedoch erheblich.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ziel der Arbeit<\/jats:title>\n                <jats:p>Dieser Artikel gibt eine \u00dcbersicht \u00fcber den technischen Hintergrund sowie die Indikationen des Pikosekundenlasers in der dermatologischen Lasermedizin und erl\u00e4utert die M\u00f6glichkeiten und Grenzen dieses Lasersystems.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Material und Methoden<\/jats:title>\n                <jats:p>Grundlage dieses Beitrages sind systematische Literaturanalyse sowie Erfahrungen aus der klinischen Praxis in der universit\u00e4ren Laserambulanz.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Der Pikosekundenlaser erm\u00f6glicht durch Impulse im Pikosekundenbereich und den Wirkmechanismus des \u201elaser-induced optical breakdown\u201c eine besonders schonende und effektive Behandlung. Im Vergleich zu den g\u00fctegeschalteten Lasern weist der Pikosekundenlaser weniger hitzeinduzierte Nebenwirkungen auf und geht mit einer geringeren Schmerzintensit\u00e4t sowie einer k\u00fcrzeren Ausfallzeit einher. Insbesondere durch die fraktionierte nichtablative Anwendung haben sich zus\u00e4tzliche Anwendungsgebiete ergeben, darunter die Hautverj\u00fcngung und Narbentherapie.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Schlussfolgerung<\/jats:title>\n                <jats:p>Der Pikosekundenlaser findet ein breites Anwendungsspektrum in der dermatologischen Lasermedizin. Die aktuelle Datenlage deutet darauf hin, dass der Laser eine effektive Methode mit einem geringen Nebenwirkungsprofil ist. Um die Wirksamkeit, Vertr\u00e4glichkeit und Patientenzufriedenheit evidenzbasiert beurteilen zu k\u00f6nnen, sind weitere prospektive Studien notwendig.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00105-023-05144-3","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T14:05:42Z","timestamp":1682517942000},"page":"440-447","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Pikosekundenlaser in der Dermatologie","Picosecond lasers in dermatology"],"prefix":"10.1007","volume":"74","author":[{"given":"Lynhda","family":"Nguyen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan W.","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Herberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,4,26]]},"reference":[{"key":"5144_CR1","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1002\/lsm.22354","volume":"47","author":"H Alabdulrazzaq","year":"2015","unstructured":"Alabdulrazzaq\u00a0H, Brauer\u00a0JA, Bae\u00a0YS et al (2015) Clearance of yellow tattoo ink with a\u00a0novel 532-nm picosecond laser. Lasers Surg Med 47:285\u2013288","journal-title":"Lasers Surg Med"},{"key":"5144_CR2","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1126\/science.6836297","volume":"220","author":"RR Anderson","year":"1983","unstructured":"Anderson\u00a0RR, Parrish\u00a0JA (1983) Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science 220:524\u2013527","journal-title":"Science"},{"key":"5144_CR3","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1001\/archderm.1996.03890280068009","volume":"132","author":"ML Armstrong","year":"1996","unstructured":"Armstrong\u00a0ML, Stuppy\u00a0DJ, Gabriel\u00a0DC et\u00a0al (1996) Motivation for tattoo removal. Arch Dermatol 132:412\u2013416","journal-title":"Arch Dermatol"},{"key":"5144_CR4","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1002\/lsm.22655","volume":"49","author":"M Balu","year":"2017","unstructured":"Balu\u00a0M, Lentsch\u00a0G, Korta\u00a0DZ et al (2017) In vivo multiphoton-microscopy of picosecond-laser-induced optical breakdown in human skin. Lasers Surg Med 49:555\u2013562","journal-title":"Lasers Surg Med"},{"key":"5144_CR5","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1001\/jamadermatol.2017.2807","volume":"153","author":"DA Belkin","year":"2017","unstructured":"Belkin\u00a0DA, Neckman\u00a0JP, Jeon\u00a0H et\u00a0al (2017) Response to laser treatment of cafe au lait macules based on morphologic features. JAMA Dermatol 153:1158\u20131161","journal-title":"JAMA Dermatol"},{"key":"5144_CR6","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1007\/s00103-019-02999-7","volume":"62","author":"A Borkenhagen","year":"2019","unstructured":"Borkenhagen\u00a0A, Mirastschijski\u00a0U, Petrowski\u00a0K et\u00a0al (2019) Tattoos in Germany: prevalence, demographics, and health orientation. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 62:1077\u20131082","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"key":"5144_CR7","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1001\/jamadermatol.2014.3045","volume":"151","author":"JA Brauer","year":"2015","unstructured":"Brauer\u00a0JA, Kazlouskaya\u00a0V, Alabdulrazzaq\u00a0H et\u00a0al (2015) Use of a\u00a0picosecond pulse duration laser with specialized optic for treatment of facial acne scarring. JAMA Dermatol 151:278\u2013284","journal-title":"JAMA Dermatol"},{"key":"5144_CR8","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1002\/lsm.23316","volume":"53","author":"Q Cen","year":"2021","unstructured":"Cen\u00a0Q, Gu\u00a0Y, Luo\u00a0L et al (2021) Comparative effectiveness of 755-nm picosecond laser, 755- and 532-nm nanosecond lasers for treatment of cafe-au-lait macules (CALms): a randomized, split-lesion clinical trial. Lasers Surg Med 53:435\u2013442","journal-title":"Lasers Surg Med"},{"key":"5144_CR9","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1002\/lsm.23103","volume":"51","author":"MWM Chan","year":"2019","unstructured":"Chan\u00a0MWM, Shek\u00a0SY, Yeung\u00a0CK et\u00a0al (2019) A prospective study in the treatment of lentigines in asian skin using 532\u202fnm picosecond Nd:YAG laser. Lasers Surg Med 51:767\u2013773","journal-title":"Lasers Surg Med"},{"key":"5144_CR10","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1007\/s10103-019-02891-5","volume":"35","author":"P Chayavichitsilp","year":"2020","unstructured":"Chayavichitsilp\u00a0P, Limtong\u00a0P, Triyangkulsri\u00a0K et al (2020) Comparison of fractional neodymium-doped yttrium aluminum garnet (Nd:YAG) 1064-nm picosecond laser and fractional 1550-nm erbium fiber laser in facial acne scar treatment. Lasers Med Sci 35:695\u2013700","journal-title":"Lasers Med Sci"},{"key":"5144_CR11","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1002\/lsm.22763","volume":"50","author":"C Dierickx","year":"2018","unstructured":"Dierickx\u00a0C (2018) Using normal and high pulse coverage with picosecond laser treatment of wrinkles and acne scarring: long term clinical observations. Lasers Surg Med 50:51\u201355","journal-title":"Lasers Surg Med"},{"key":"5144_CR12","doi-asserted-by":"publisher","first-page":"164","DOI":"10.12788\/j.sder.0117","volume":"33","author":"JR Freedman","year":"2014","unstructured":"Freedman\u00a0JR, Kaufman\u00a0J, Metelitsa\u00a0AI et al (2014) Picosecond lasers: the next generation of short-pulsed lasers. Semin Cutan Med Surg 33:164\u2013168","journal-title":"Semin Cutan Med Surg"},{"key":"5144_CR13","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/j.jaad.2019.03.016","volume":"83","author":"Y Ge","year":"2020","unstructured":"Ge\u00a0Y, Yang\u00a0Y, Guo\u00a0L et al (2020) Comparison of a\u00a0picosecond alexandrite laser versus a\u00a0Q-switched alexandrite laser for the treatment of nevus of Ota: A randomized, split-lesion, controlled trial. J\u00a0Am Acad Dermatol 83:397\u2013403","journal-title":"J Am Acad Dermatol"},{"key":"5144_CR14","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1097\/DSS.0000000000000922","volume":"43","author":"L Guss","year":"2017","unstructured":"Guss\u00a0L, Goldman\u00a0MP, Wu\u00a0DC (2017) Picosecond 532\u202fnm neodymium-doped yttrium ayluminium garnet laser for the treatment of solar lentigines in darker skin types: safety and efficacy. Dermatol Surg 43:456\u2013459","journal-title":"Dermatol Surg"},{"key":"5144_CR15","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1007\/s10103-012-1179-z","volume":"28","author":"L Habbema","year":"2013","unstructured":"Habbema\u00a0L, Verhagen\u00a0R, Van Hal\u00a0R et al (2013) Efficacy of minimally invasive nonthermal laser-induced optical breakdown technology for skin rejuvenation. Lasers Med Sci 28:935\u2013940","journal-title":"Lasers Med Sci"},{"key":"5144_CR16","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1002\/jbio.201100083","volume":"5","author":"L Habbema","year":"2012","unstructured":"Habbema\u00a0L, Verhagen\u00a0R, Van Hal\u00a0R et al (2012) Minimally invasive non-thermal laser technology using laser-induced optical breakdown for skin rejuvenation. J\u00a0Biophotonics 5:194\u2013199","journal-title":"J Biophotonics"},{"key":"5144_CR17","volume-title":"Laser Tattoo Removal","author":"JK Henley","year":"2022","unstructured":"Henley\u00a0JK, Zurfley\u00a0F, Ramsey\u00a0ML (2022) Laser Tattoo Removal. StatPearls, Treasure Island (FL)"},{"key":"5144_CR18","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1016\/S0190-9622(99)70444-5","volume":"40","author":"RM Herd","year":"1999","unstructured":"Herd\u00a0RM, Alora\u00a0MB, Smoller\u00a0B et al (1999) A clinical and histologic prospective controlled comparative study of the picosecond titanium:sapphire (795\u202fnm) laser versus the Q\u2011switched alexandrite (752\u202fnm) laser for removing tattoo pigment. J\u00a0Am Acad Dermatol 40:603\u2013606","journal-title":"J Am Acad Dermatol"},{"key":"5144_CR19","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1002\/lsm.10065","volume":"30","author":"DD Ho","year":"2002","unstructured":"Ho\u00a0DD, London\u00a0R, Zimmerman\u00a0GB et al (2002) Laser-tattoo removal\u2014a study of the mechanism and the optimal treatment strategy via computer simulations. Lasers Surg Med 30:389\u2013397","journal-title":"Lasers Surg Med"},{"key":"5144_CR20","doi-asserted-by":"publisher","first-page":"274","DOI":"10.5978\/islsm.17-RE-02","volume":"26","author":"K Kasai","year":"2017","unstructured":"Kasai\u00a0K (2017) Picosecond laser treatment for tattoos and benign cutaneous pigmented lesions (secondary publication). Laser Ther 26:274\u2013281","journal-title":"Laser Ther"},{"key":"5144_CR21","doi-asserted-by":"publisher","first-page":"1434","DOI":"10.1097\/DSS.0000000000001257","volume":"43","author":"ANB Kauvar","year":"2017","unstructured":"Kauvar\u00a0ANB, Keaney\u00a0TC, Alster\u00a0T (2017) Laser treatment of professional tattoos with a\u00a01064\/532-nm dual-wavelength picosecond laser. Dermatol Surg 43:1434\u20131440","journal-title":"Dermatol Surg"},{"key":"5144_CR22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1524-4725.2011.02187.x","volume":"38","author":"KM Kent","year":"2012","unstructured":"Kent\u00a0KM, Graber\u00a0EM (2012) Laser tattoo removal: a\u00a0review. Dermatol Surg 38:1\u201313","journal-title":"Dermatol Surg"},{"key":"5144_CR23","doi-asserted-by":"publisher","first-page":"47","DOI":"10.5978\/islsm.20-OR-07","volume":"29","author":"T Kono","year":"2020","unstructured":"Kono\u00a0T, Chan\u00a0HHL, Groff\u00a0WF et\u00a0al (2020) Prospective comparison study of 532\/1064\u202fnm picosecond laser vs 532\/1064\u202fnm nanosecond laser in the treatment of professional tattoos in Asians. Laser Ther 29:47\u201352","journal-title":"Laser Ther"},{"key":"5144_CR24","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1080\/14764172.2019.1683581","volume":"21","author":"G Kurmus","year":"2019","unstructured":"Kurmus\u00a0G, Tatliparmak\u00a0A, Aksoy\u00a0B et\u00a0al (2019) Efficacy and safety of 1927\u202fnm fractional Thulium fiber laser for the treatment of melasma: a\u00a0retrospective study of 100\u00a0patients. J\u00a0Cosmet Laser Ther 21:408\u2013411","journal-title":"J Cosmet Laser Ther"},{"key":"5144_CR25","doi-asserted-by":"publisher","first-page":"2907","DOI":"10.1111\/jdv.16643","volume":"34","author":"HH Kwon","year":"2020","unstructured":"Kwon\u00a0HH, Yang\u00a0SH, Cho\u00a0YJ et al (2020) Comparison of a\u00a01064-nm neodymium-doped yttrium aluminum garnet picosecond laser using a\u00a0diffractive optical element vs. a\u00a0nonablative 1550-nm erbium-glass laser for the treatment of facial acne scarring in Asian patients: a\u00a017-week prospective, randomized, split-face, controlled trial. J\u00a0Eur Acad Dermatol Venereol 34:2907\u20132913","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"5144_CR26","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1080\/14764172.2022.2100915","volume":"24","author":"DW Lee","year":"2022","unstructured":"Lee\u00a0DW, Ryu\u00a0H, Choi\u00a0HJ et al (2022) Improvement in linear depressed atrophic scar using 755-nm picosecond alexandrite laser vs. ablative fractional carbon dioxide laser. J\u00a0Cosmet Laser Ther 24:48\u201355","journal-title":"J Cosmet Laser Ther"},{"key":"5144_CR27","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1111\/dsu.12176","volume":"39","author":"HM Lee","year":"2013","unstructured":"Lee\u00a0HM, Haw\u00a0S, Kim\u00a0JK et al (2013) Split-face study using a\u00a01,927-nm thulium fiber fractional laser to treat photoaging and melasma in Asian skin. Dermatol Surg 39:879\u2013888","journal-title":"Dermatol Surg"},{"key":"5144_CR28","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1007\/s10103-018-2529-2","volume":"33","author":"MC Lee","year":"2018","unstructured":"Lee\u00a0MC, Lin\u00a0YF, Hu\u00a0S et al (2018) A split-face study: comparison of picosecond alexandrite laser and Q\u2011switched Nd:YAG laser in the treatment of melasma in Asians. Lasers Med Sci 33:1733\u20131738","journal-title":"Lasers Med Sci"},{"key":"5144_CR29","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1111\/jdv.14492","volume":"32","author":"A Lorgeou","year":"2018","unstructured":"Lorgeou\u00a0A, Perrillat\u00a0Y, Gral\u00a0N et\u00a0al (2018) Comparison of two picosecond lasers to a\u00a0nanosecond laser for treating tattoos: a\u00a0prospective randomized study on 49\u00a0patients. J\u00a0Eur Acad Dermatol Venereol 32:265\u2013270","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"5144_CR30","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/s40257-019-00488-w","volume":"21","author":"J Mckesey","year":"2020","unstructured":"Mckesey\u00a0J, Tovar-Garza\u00a0A, Pandya\u00a0AG (2020) Melasma Treatment: An Evidence-Based Review. Am J Clin Dermatol 21:173\u2013225","journal-title":"Am J Clin Dermatol"},{"key":"5144_CR31","doi-asserted-by":"publisher","unstructured":"Neagu N, Conforti C, Agozzino M et\u00a0al (2021) Melasma treatment: a\u00a0systematic review. J\u00a0Dermatolog Treat: 1\u201339. https:\/\/doi.org\/10.1080\/09546634.2021.1914313","DOI":"10.1080\/09546634.2021.1914313"},{"key":"5144_CR32","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1002\/lsm.22820","volume":"50","author":"K Negishi","year":"2018","unstructured":"Negishi\u00a0K, Akita\u00a0H, Matsunaga\u00a0Y (2018) Prospective study of removing solar lentigines in Asians using a\u00a0novel dual-wavelength and dual-pulse width picosecond laser. Lasers Surg Med 50:851\u2013858","journal-title":"Lasers Surg Med"},{"key":"5144_CR33","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1111\/jdv.15497","volume":"33","author":"T Passeron","year":"2019","unstructured":"Passeron\u00a0T, Genedy\u00a0R, Salah\u00a0L et\u00a0al (2019) Laser treatment of hyperpigmented lesions: position statement of the European Society of Laser in Dermatology. J\u00a0Eur Acad Dermatol Venereol 33:987\u20131005","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"5144_CR34","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1097\/00000637-199811000-00018","volume":"41","author":"C Raulin","year":"1998","unstructured":"Raulin\u00a0C, Schonermark\u00a0MP, Greve\u00a0B et al (1998) Q\u2011switched ruby laser treatment of tattoos and benign pigmented skin lesions: a\u00a0critical review. Ann Plast Surg 41:555\u2013565","journal-title":"Ann Plast Surg"},{"key":"5144_CR35","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1001\/archderm.134.2.167","volume":"134","author":"V Ross","year":"1998","unstructured":"Ross\u00a0V, Naseef\u00a0G, Lin\u00a0G et al (1998) Comparison of responses of tattoos to picosecond and nanosecond Q\u2011switched neodymium: YAG lasers. Arch Dermatol 134:167\u2013171","journal-title":"Arch Dermatol"},{"key":"5144_CR36","doi-asserted-by":"publisher","first-page":"e58","DOI":"10.1097\/DSS.0000000000002572","volume":"47","author":"P Sirithanabadeekul","year":"2021","unstructured":"Sirithanabadeekul\u00a0P, Tantrapornpong\u00a0P, Rattakul\u00a0B et al (2021) Comparison of fractional picosecond 1064-nm laser and fractional carbon dioxide laser for treating atrophic acne scars: a randomized split-face trial. Dermatol Surg 47:e58\u2013e65","journal-title":"Dermatol Surg"},{"key":"5144_CR37","doi-asserted-by":"publisher","unstructured":"Sirithanabadeekul P, Tantrapornpong P, Rattakul B et al (2020) Comparison of fractional picosecond 1064-nm laser and fractional carbon dioxide laser for treating atrophic acne scars: a randomized split-face trial. Dermatol Surg. https:\/\/doi.org\/10.1097\/DSS.0000000000002572","DOI":"10.1097\/DSS.0000000000002572"},{"key":"5144_CR38","doi-asserted-by":"publisher","first-page":"148","DOI":"10.12788\/j.sder.2017.032","volume":"36","author":"EA Tanghetti","year":"2017","unstructured":"Tanghetti\u00a0EA, Hoffmann\u00a0KA, Hoffmann\u00a0K (2017) Short-pulsed laser for the treatment of tattoos, pigmented lesions, scars and rejuvenation. Semin Cutan Med Surg 36:148\u2013154","journal-title":"Semin Cutan Med Surg"},{"key":"5144_CR39","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1046\/j.1365-2133.1999.02714.x","volume":"140","author":"S Varma","year":"1999","unstructured":"Varma\u00a0S, Lanigan\u00a0SW (1999) Reasons for requesting laser removal of unwanted tattoos. Br J Dermatol 140:483\u2013485","journal-title":"Br J Dermatol"},{"key":"5144_CR40","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1016\/j.jaad.2006.01.012","volume":"54","author":"CC Wang","year":"2006","unstructured":"Wang\u00a0CC, Sue\u00a0YM, Yang\u00a0CH et al (2006) A comparison of Q\u2011switched alexandrite laser and intense pulsed light for the treatment of freckles and lentigines in Asian persons: a\u00a0randomized, physician-blinded, split-face comparative trial. J\u00a0Am Acad Dermatol 54:804\u2013810","journal-title":"J Am Acad Dermatol"},{"key":"5144_CR41","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1111\/jdv.15934","volume":"34","author":"YJ Wang","year":"2020","unstructured":"Wang\u00a0YJ, Lin\u00a0ET, Chen\u00a0YT et\u00a0al (2020) Prospective randomized controlled trial comparing treatment efficacy and tolerance of picosecond alexandrite laser with a\u00a0diffractive lens array and triple combination cream in female asian patients with melasma. J\u00a0Eur Acad Dermatol Venereol 34:624\u2013632","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"5144_CR42","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1002\/lsm.22577","volume":"49","author":"RA Weiss","year":"2017","unstructured":"Weiss\u00a0RA, Mcdaniel\u00a0DH, Weiss\u00a0MA et\u00a0al (2017) Safety and efficacy of a\u00a0novel diffractive lens array using a\u00a0picosecond 755\u202fnm alexandrite laser for treatment of wrinkles. Lasers Surg Med 49:40\u201344","journal-title":"Lasers Surg Med"}],"container-title":["Die Dermatologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-023-05144-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00105-023-05144-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-023-05144-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T17:01:55Z","timestamp":1686157315000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00105-023-05144-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,26]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["5144"],"URL":"https:\/\/doi.org\/10.1007\/s00105-023-05144-3","relation":{},"ISSN":["2731-7005","2731-7013"],"issn-type":[{"value":"2731-7005","type":"print"},{"value":"2731-7013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,26]]},"assertion":[{"value":"23 March 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"K.\u00a0Herberger hat Vortr\u00e4ge f\u00fcr die Firma Lutronic gehalten. Die Firma Lutronic hat Forschungsprojekte der Laserabteilung am UKE unterst\u00fctzt, indem ein Radiofrequenzmikroneedling-System (Genius\u00ae) und ein Laser (DermaV\u00ae) f\u00fcr jeweils eine klinische Studie zur Verf\u00fcgung gestellt wurden. L.\u00a0Nguyen und S.W.\u00a0Schneider geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"Alle Patienten, die \u00fcber Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts zu identifizieren sind, haben hierzu ihre schriftliche Einwilligung gegeben. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}