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Kutane Neurofibrome k\u00f6nnen f\u00fcr Patienten sehr belastend sein und tragen v.\u00a0a. an \u00e4u\u00dferlich sichtbaren oder funktionell relevanten K\u00f6rperstellen zu einer Verminderung der Lebensqualit\u00e4t bei. Die vorliegende Arbeit soll zeigen, inwiefern durch eine Resektion kutaner Neurofibrome eine Verbesserung der Lebensqualit\u00e4t bewirkt werden kann.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodik<\/jats:title><jats:p>Wir f\u00fchrten eine retrospektive Datenerhebung per Fragebogen zur Lebensqualit\u00e4t vor und nach der Operation kutaner Neurofibrome in der Universit\u00e4tshautklinik durch. Verwendet wurden ein adaptierter dermatologischer Lebensqualit\u00e4tsindex sowie ein in unserer Hautklinik eingesetzter postoperativer Fragebogen zu Komplikationen und Patientenzufriedenheit. Zudem wurden Daten der Patienten aus Arztbriefen, Operationsberichten und Ambulanzdokumentationen entnommen. Befragt wurden 30\u00a0Patienten mit Neurofibromatose Typ\u00a01, die innerhalb der Jahre 2016 bis 2020 in der Hautklinik T\u00fcbingen ambulant oder station\u00e4r operiert wurden. Die Befragungsergebnisse wurden statistisch ausgewertet und als absolute und relative H\u00e4ufigkeiten dargestellt.<\/jats:p><\/jats:sec><jats:sec><jats:title>Ergebnisse<\/jats:title><jats:p>Unsere Studie zeigt eine Verbesserung der Lebensqualit\u00e4t nach operativer Therapie kutaner Neurofibrome, hinsichtlich Einschr\u00e4nkungen im Alltag, Befangenheit, Einschr\u00e4nkungen der Kleiderwahl und der Freizeitgestaltung. Dabei kam es bei der Mehrheit der Patienten zu keinem neuen Auftreten von Neurofibromen im Operationsgebiet; Komplikationen wie Nachblutungen oder Wundinfekte fallen in unserer Studie moderat bis gering aus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Diskussion<\/jats:title><jats:p>In Relation zu hoher Zufriedenheit mit dem operativen und kosmetischen Ergebnis sowie positivem Einfluss auf die Lebensqualit\u00e4t spricht dies f\u00fcr ein g\u00fcnstiges Risiko-Nutzen-Verh\u00e4ltnis der Resektion kutaner Neurofibrome bei Neurofibromatose\u00a0I.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00105-023-05220-8","type":"journal-article","created":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T15:04:06Z","timestamp":1695222246000},"page":"961-968","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Kosmetische und funktionelle Ergebnisse nach Resektion kutaner Neurofibrome bei Neurofibromatose\u00a0I","Cosmetic and functional results after resection of cutaneous neurofibroma in neurofibromatosis\u00a0type\u00a01"],"prefix":"10.1007","volume":"74","author":[{"given":"Benjamin","family":"Walz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Pfefferle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Martin","family":"H\u00e4fner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Kofler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,9,20]]},"reference":[{"issue":"2","key":"5220_CR1","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1055\/s-0036-1579766","volume":"5","author":"JL Kresak","year":"2016","unstructured":"Kresak\u00a0JL, Walsh\u00a0M (2016) Neurofibromatosis: a\u00a0review of NF1, NF2, and Schwannomatosis. 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