{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T13:03:27Z","timestamp":1764680607492,"version":"3.46.0"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"},{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"}],"funder":[{"name":"Universit\u00e4tsklinikum Augsburg"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dermatologie"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Ein 63-j\u00e4hriger Patient mit kutanen Metastasen eines malignen Melanoms zeigte unter kombinierter Immuntherapie mit Ipilimumab und Nivolumab eine ausgepr\u00e4gte therapeutische Antwort. 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Cancers (basel) 15:","DOI":"10.3390\/cancers15174222"}],"container-title":["Die Dermatologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-025-05550-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00105-025-05550-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00105-025-05550-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T12:59:06Z","timestamp":1764680346000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00105-025-05550-9"}},"subtitle":["Analyse von Mikromilieu und Gef\u00e4\u00dfstruktur unter Therapie","Microenvironment and vascular insights in therapy"],"short-title":[],"issued":{"date-parts":[[2025,7,29]]},"references-count":6,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["5550"],"URL":"https:\/\/doi.org\/10.1007\/s00105-025-05550-9","relation":{},"ISSN":["2731-7005","2731-7013"],"issn-type":[{"type":"print","value":"2731-7005"},{"type":"electronic","value":"2731-7013"}],"subject":[],"published":{"date-parts":[[2025,7,29]]},"assertion":[{"value":"29 June 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 July 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"O.\u00a0Mayer erhielt Reisekostenunterst\u00fctzung von Lilly, Novartis, Galderma und AbbVie. J.\u00a0Welzel war Pr\u00e4sidentin der Deutschen Dermatologischen Gesellschaft und erhielt institutionelle F\u00f6rderungen durch die EU, das BMWK und das BMBF. Sie erhielt Beratungs- und Vortragshonorare sowie Reisekostenunterst\u00fctzungen von Almirall, AbbVie, Leo, Novartis, BMS, Boehringer Ingelheim, Lilly, Galderma und Janssen. Zudem war sie Mitglied in Data Safety Monitoring Boards bzw. Advisory Boards der Firmen Almirall, Leo, Novartis, Boehringer Ingelheim und Janssen. S.\u00a0Schuh erhielt Reisekostenunterst\u00fctzung von Lilly, Almirall, Galderma und AVOXA sowie Vortragshonorare von AVOXA, Lilly und Galderma. R.\u00a0Sch\u00f6nherr gibt an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patient\/-innen zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern\/Vertreterinnen eine schriftliche Einwilligung vor. Ein Ethikvotum war im vorliegenden Fall nicht erforderlich.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}