{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T08:43:15Z","timestamp":1648802595380},"reference-count":98,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2004,7,1]],"date-time":"2004-07-01T00:00:00Z","timestamp":1088640000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HNO"],"published-print":{"date-parts":[[2004,7]]},"DOI":"10.1007\/s00106-004-1075-3","type":"journal-article","created":{"date-parts":[[2004,3,23]],"date-time":"2004-03-23T12:32:27Z","timestamp":1080045147000},"page":"590-598","source":"Crossref","is-referenced-by-count":2,"title":["Alkoholinduzierte Erkrankungen im Kopf-Hals-Bereich"],"prefix":"10.1007","volume":"52","author":[{"given":"F.","family":"Riedel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"H\u00f6rmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2004,7,1]]},"reference":[{"key":"1075_CR1","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/0030-4220(76)90230-9","volume":"41","author":"Abelson","year":"1976","unstructured":"Abelson DC, Mandel ID, Karmiol M (1976) Salivary studies in alcoholic cirrhosis. Oral Surg Oral Med Oral Pathol 41: 188\u2013192","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"1075_CR2","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/BF00051354","volume":"3","author":"Adami","year":"1992","unstructured":"Adami HO, McLaughlin JK, Hsing AW et al. (1992) Alcoholism and cancer risk: a population-based cohort study. Cancer Causes Control 3: 419\u2013425","journal-title":"Cancer Causes Control"},{"key":"1075_CR3","first-page":"7","volume":"32","author":"Bardell","year":"1971","unstructured":"Bardell D and Smith EJ (1971) An in vitro study of mixed populations of normal oropharyngeal bacteria after exposure to cigarette smoke in vitro. Microbios 32: 7\u201313","journal-title":"Microbios"},{"key":"1075_CR4","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1902\/jop.1978.49.9.480","volume":"49","author":"Bastiaan","year":"1978","unstructured":"Bastiaan RJ and Waite IM (1978) Effect of tobacco smoke on plaque development and gingivitis. J Periodontology 49: 480\u2013482","journal-title":"J Periodontology"},{"key":"1075_CR5","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0165-1218(82)90155-0","volume":"101","author":"Bird","year":"1982","unstructured":"Bird RP, Draper HH, Basrur PK (1982) Effects of malonaldehyde and acetaldehyde on cultured mammalian cells. Production of micronuclei and chromosomal aberrations. Mutation Res 101: 237\u2013246","journal-title":"Mutation Res"},{"key":"1075_CR6","first-page":"3282","volume":"48","author":"Blot","year":"1988","unstructured":"Blot WJ, Mc Laughlin JK, Winn DM et al. (1988) Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res 48: 3282\u20133287","journal-title":"Cancer Res"},{"key":"1075_CR7","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1164\/arrd.1984.130.2.156","volume":"130","author":"Bonora","year":"1984","unstructured":"Bonora M, Shields GI, Knuth SL, Bartlett JD (1984) Selective depression by ethanol of upper airway respiratory motor activity in cats. Am Rev Respir Dis 130: 156\u2013161","journal-title":"Am Rev Respir Dis"},{"key":"1075_CR8","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1097\/00001622-199006000-00017","volume":"2","author":"Boyle","year":"1990","unstructured":"Boyle P, Zheng T, Macfarlane GJ et al. (1990) Recent advances in the etiology and epidemiology of head and neck cancer. Curr Opin Oncol 2: 539\u2013545","journal-title":"Curr Opin Oncol"},{"key":"1075_CR9","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1159\/000225127","volume":"33","author":"Bross","year":"1976","unstructured":"Bross ID, Coombs J (1976) Early onset of oral cancer among women who drink and smoke. Oncology 33: 136\u2013139","journal-title":"Oncology"},{"key":"1075_CR10","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/1097-0142(19860115)57:2<391::AID-CNCR2820570235>3.0.CO;2-Q","volume":"57","author":"Brugere","year":"1986","unstructured":"Brugere J, Guenel P, Leclerc A et al. (1986) Differential effects of tobacco and alcohol in cancer of the larynx, pharynx and mouth. Cancer 57: 391\u2013395","journal-title":"Cancer"},{"key":"1075_CR11","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF00051681","volume":"6","author":"Bundgaard","year":"1995","unstructured":"Bundgaard T, Wildt J, Frydenberg M et al. (1995) Case-control study of squamous cell cancer of the oral cavity in Denmark. Cancer Causes Control 6: 57\u201367","journal-title":"Cancer Causes Control"},{"key":"1075_CR12","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/ijc.2910450302","volume":"45","author":"Carstensen","year":"1990","unstructured":"Carstensen JM, Bygren LO, Hatschek T (1990) Cancer incidence among Swedish brewery workers. Int J Cancer 45: 393\u2013396","journal-title":"Int J Cancer"},{"key":"1075_CR13","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1834-7819.1976.tb02833.x","volume":"21","author":"Colman","year":"1976","unstructured":"Colman G, Beighton D, Chalk AJ et al. (1976) Cigarette smoking and the microbial flora of the mouth. Austral Dent J 21: 111\u2013118","journal-title":"Austral Dent J"},{"key":"1075_CR14","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1093\/jnci\/88.8.542","volume":"88","author":"Deleyiannis","year":"1996","unstructured":"Deleyiannis FW, Thomas DB, Vaughan TL et al. (1996) Alcoholism: independent predictor of survival in patients with head and neck cancer. J Natl Cancer Inst 88: 542\u2013549","journal-title":"J Natl Cancer Inst"},{"key":"1075_CR15","doi-asserted-by":"crossref","unstructured":"Dellarco VL (1988) A mutagenicity assessment of acetaldehyde. Mutation Res 195, 1\u201320","DOI":"10.1016\/0165-1110(88)90013-9"},{"key":"1075_CR16","first-page":"225","volume":"7","author":"Dijk","year":"1992","unstructured":"Dijk DJ, Brunner DP, Eschbach D, Tobler I, Borb\u00e9ly AA (1992): The effect of ethanol on human sleep EEG power spectra differ from thosen benzodiazepine receptor agonists. Neuropsychopharmacology 7: 225","journal-title":"Neuropsychopharmacology"},{"key":"1075_CR17","first-page":"1073","volume":"65","author":"Enstrom","year":"1980","unstructured":"Enstrom JE (1980) Cancer mortality among Mormons in California during 1968\u201375. J Natl Cancer Inst 65: 1073\u20131082","journal-title":"J Natl Cancer Inst"},{"key":"1075_CR18","unstructured":"Erckenbrecht JF (1996) Speiser\u00f6hre\u2014Physiologie und Pathophysiologie. In: Hahn EG, Riemann JF (Hrsg) Klinische Gastroenterologie, 3.\u00a0Aufl. Thieme, Stuttgart, S\u00a0506\u2013514"},{"key":"1075_CR19","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/0091-7435(75)90032-8","volume":"4","author":"Feldman","year":"1975","unstructured":"Feldman JG, Hazan M (1975). A case-control investigation of alcohol, tobacco, and diet in head and neck cancer. Prevent Med 4: 444\u2013463","journal-title":"Prevent Med"},{"key":"1075_CR20","first-page":"120","volume":"41","author":"Garro","year":"1981","unstructured":"Garro AJ, Seitz HK, Lieber CS (1981) Enhancement of dimethylnitrosamine metabolism and activation to a mutagen following chronic ethanol consumption. Cancer Res 41: 120\u2013124","journal-title":"Cancer Res"},{"key":"1075_CR21","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1093\/jnci\/59.6.1611","volume":"59","author":"Graham","year":"1977","unstructured":"Graham S, Dayal H, Rohrer T et al. (1977) Dentition, diet, tobacco, and alcohol in the epidemiology of oral cancer. J Natl Cancer Inst 59: 1611\u20131618","journal-title":"J Natl Cancer Inst"},{"key":"1075_CR22","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1136\/bmj.317.7162.844","volume":"317","author":"Gronbaek","year":"1998","unstructured":"Gronbaek M, Becker U, Johansen D et al. (1998) Population based cohort study of the association between alcohol intake and cancer of the upper digestive tract. Br Med J 317: 844\u2013847","journal-title":"Br Med J"},{"key":"1075_CR23","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1093\/jnci\/89.22.1698","volume":"89","author":"Harty","year":"1997","unstructured":"Harty IC, Caporaso NE, Hayes RB et al. (1997) Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers. J Natl Cancer Inst 89: 1698\u20131705","journal-title":"J Natl Cancer Inst"},{"key":"1075_CR24","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0165-7992(91)90124-M","volume":"264","author":"Helander","year":"1991","unstructured":"Helander A, Lindahl-Kiessling K (1991) Increased frequency of acetaldehyde-induced sister-chromatid exchanges in human lymphocytes treated with an aldehyde dehydrogenase inhibitor. Mutation Res 264: 103\u2013107","journal-title":"Mutation Res"},{"key":"1075_CR25","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/bjc.1981.26","volume":"43","author":"Herity","year":"1981","unstructured":"Herity B, Moriarty M, Bourke GJ et al. (1981) A case-control study of head and neck cancer in the Republic of Ireland. Br J Cancer 43: 177\u2013182","journal-title":"Br J Cancer"},{"key":"1075_CR26","doi-asserted-by":"crossref","first-page":"141","DOI":"10.5694\/j.1326-5377.1996.tb122011.x","volume":"164","author":"Holman","year":"1996","unstructured":"Holman CD, English DR, Milne E, Winter MG (1996) Meta-analysis of alcohol and all-cause mortality: a validation of NHMRC recommendations. Med J Aust 164: 141\u2013145","journal-title":"Med J Aust"},{"key":"1075_CR27","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1093\/carcin\/18.9.1739","volume":"18","author":"Homann","year":"1997","unstructured":"Homann N, Jousimies-Somer H, Jokelainen K et al. (1997) High acetaldehyde levels in saliva after ethanol consumption: methodological aspects and pathogenetic implications. Carcinogenesis 18: 1739\u20131743","journal-title":"Carcinogenesis"},{"key":"1075_CR28","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1093\/jnci\/89.22.1692","volume":"89","author":"Homann","year":"1997","unstructured":"Homann N, K\u00e4rkk\u00e4inen P, Koivisto T et al. (1997) Effect of acetaldehyde on cell regeneration and differentiation of the upper gastrointestinal tract mucosa. J Natl Cancer Inst 89: 1692\u20131697","journal-title":"J Natl Cancer Inst"},{"key":"1075_CR29","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1093\/carcin\/21.4.663","volume":"21","author":"Homann","year":"2000","unstructured":"Homann N, Tillonen J, Meurman JH et al. (2000) Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer. Carcinogenesis 21: 663\u2013668","journal-title":"Carcinogenesis"},{"key":"1075_CR30","unstructured":"H\u00f6rmann K, Riedel F, Hirth K (2002) Alkohol und Mundh\u00f6hle\/Pharynx. In: Singer MV, Teyssen S: Alkohol und Alkoholfolgeerkrankungen. Grundlagen\u2014Diagnostik\u2014Therapie, Kap\u00a012. Springer, Berlin Heidelberg New York Tokio"},{"key":"1075_CR31","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1034\/j.1601-0825.2001.00731.x","volume":"7","author":"Howie","year":"2001","unstructured":"Howie NM, Trigkas TK, Cruchley AT et al. (2001) Short-term exposure to alcohol increases the permeability of human oral mucosa. Oral Dis 7: 349\u2013354","journal-title":"Oral Dis"},{"key":"1075_CR32","first-page":"1995","volume":"11","author":"Hsu","year":"1991","unstructured":"Hsu TC, Furlong C (1991) The role of ethanol in oncogenesis of the upper aerodigestive tract; inhibition of DNA repair. Anticancer Res 11: 1995\u20131998","journal-title":"Anticancer Res"},{"key":"1075_CR33","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1136\/jnnp.45.4.353","volume":"45","author":"Issa","year":"1982","unstructured":"Issa FG, Sullivan CE (1982): Alcohol, snoring and sleep apnoe. J Neurol Neurosurg Psychiatry 45: 353","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1075_CR34","first-page":"151","volume":"132D","author":"Jensen","year":"1983","unstructured":"Jensen OM (1983) Dietary factors in colon carcinogenesis with special emphasis on the role of dietary fat and dietary fibre. Prog Clin Biol Res 132D: 151\u2013158","journal-title":"Prog Clin Biol Res"},{"key":"1075_CR35","first-page":"13","volume":"10","author":"Johnson","year":"1993","unstructured":"Johnson NW, Warnakulasuriya KA (1993) Epidemiology and aetiology of oral cancer in the United Kingdom. Comm Dent Health 10: 13\u201329","journal-title":"Comm Dent Health"},{"key":"1075_CR36","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1111\/j.1530-0277.1996.tb01113.x","volume":"20","author":"Jokelainen","year":"1996","unstructured":"Jokelainen K, Heikkonen E, Roine R et al. (1996) Increased acetaldehyde production by mouthwashings from patients with oral cavity, laryngeal or pharyngeal cancer. Alcohol Clin Exp Res 20: 1206\u20131210","journal-title":"Alcohol Clin Exp Res"},{"key":"1075_CR37","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1111\/j.1530-0277.1996.tb01932.x","volume":"20","author":"Jokelainen","year":"1996","unstructured":"Jokelainen K, Siitonen A, Jousimies-Somer H et al. (1996) In vitro alcohol dehydrogenase-mediated acetaldehyde production by aerobic bacteria representing the normal colonic flora in man. Alcohol Clin Exp Res 20: 967\u2013972","journal-title":"Alcohol Clin Exp Res"},{"key":"1075_CR38","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1600-0714.1993.tb00125.x","volume":"22","author":"Jovanovic","year":"1993","unstructured":"Jovanovic A, Schulten EA, Kostense PJ et al. (1993) Tobacco and alcohol related to the anatomical site of oral squamous cell carcinoma. J Oral Pathol Med 22: 459\u2013462","journal-title":"J Oral Pathol Med"},{"key":"1075_CR39","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/ijc.2910430203","volume":"43","author":"Kabat","year":"1989","unstructured":"Kabat GC, Wynder EL (1989) Type of alcoholic beverage and oral cancer. Int J Cancer 43: 190\u2013194","journal-title":"Int J Cancer"},{"key":"1075_CR40","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0964-1955(94)90056-6","volume":"30B","author":"Kato","year":"1994","unstructured":"Kato I, Nomura AM (1994) Alcohol in the aetiology of upper aerodigestive tract cancer. Eur J Cancer B Oral Oncol 30B: 75\u201381","journal-title":"Eur J Cancer B Oral Oncol"},{"key":"1075_CR41","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/0016-5085(87)90013-8","volume":"92","author":"Keshavarzian","year":"1987","unstructured":"Keshavarzian A, Iber FL, Ferguson Y (1987) Esophageal manometry and radionuclide emptying in chronic alcoholics. Gastroenterol 92: 651\u2013657","journal-title":"Gastroenterol"},{"key":"1075_CR42","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1111\/j.1530-0277.1990.tb01200.x","volume":"14","author":"Keshavarzian","year":"1990","unstructured":"Keshavarzian A, Polepalle C, Iber FL, Durkin M (1990) Esophageal motor disorder in alcoholics: result of alcoholism or withdrawal? Alcohol Clin Exp Res 14: 561\u2013567","journal-title":"Alcohol Clin Exp Res"},{"key":"1075_CR43","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/j.1530-0277.1991.tb00528.x","volume":"15","author":"Keshavarzian","year":"1991","unstructured":"Keshavarzian A, Urban G, Sedghi S, Willson C, Sabella L, Sweeny C, Anderson K (1991) Effect of acute ethanol on esophageal motility in cat. Alcohol Clin Exp Res 15: 116\u2013121","journal-title":"Alcohol Clin Exp Res"},{"key":"1075_CR44","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1001\/jama.1973.03220220076014","volume":"224","author":"Kissin","year":"1973","unstructured":"Kissin B, Kaley MM, Su WH et al. (1973) Head and neck cancer in alcoholics. The relationship to drinking, smoking, and dietary patterns. J Am Med Assoc 224: 1174\u20131175","journal-title":"J Am Med Assoc"},{"key":"1075_CR45","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1016\/S0140-6736(96)24051-6","volume":"348","author":"Kleinjans","year":"1996","unstructured":"Kleinjans JC, Moonen EJ, Dallinga JW et al. (1996) Polycyclic aromatic hydrocarbons in whiskies. Lancet 348: 1731","journal-title":"Lancet"},{"key":"1075_CR46","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0300-483X(81)90054-8","volume":"20","author":"Korte","year":"1981","unstructured":"Korte A, Wagner HM, Obe G (1981) Simultaneous exposure of Chinese hamsters to ethanol and cigarette smoke: cytogenetic aspects. Toxicology 20: 237\u2013246","journal-title":"Toxicology"},{"key":"1075_CR47","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/0277-5379(87)90315-4","volume":"23","author":"Leclerc","year":"1987","unstructured":"Leclerc A, Brugere J, Luce D et al. (1987) Type of alcoholic beverage and cancer of the upper respiratory and digestive tract. Eur J Cancer Clin Oncol 23: 529\u2013534","journal-title":"Eur J Cancer Clin Oncol"},{"key":"1075_CR48","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0165-1110(87)90004-2","volume":"186","author":"Lieber","year":"1987","unstructured":"Lieber CS, Baraona E, Leo MA et al. (1987) International Commission for Protection against Environmental Mutagens and Carcinogens. ICPEMC Working Paper No. 15\/2. Metabolism and metabolic effects of ethanol, including interaction with drugs, carcinogens and nutrition. Mutation Res 186: 201\u2013233","journal-title":"Mutation Res"},{"key":"1075_CR49","first-page":"2863","volume":"39","author":"Lieber","year":"1979","unstructured":"Lieber CS, Seitz HK, Garro AJ et al. (1979) Alcohol-related diseases and carcinogenesis. Cancer Res 39: 2863\u20132886","journal-title":"Cancer Res"},{"key":"1075_CR50","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/0266-4356(94)90098-1","volume":"32","author":"Llewelyn","year":"1994","unstructured":"Llewelyn J, Mitchell R (1994) Smoking, alcohol and oral cancer in south east Scotland: a 10-year experience. Br J Oral Maxillofacial Surg 32: 146\u2013152","journal-title":"Br J Oral Maxillofacial Surg"},{"key":"1075_CR51","doi-asserted-by":"crossref","first-page":"2608","DOI":"10.1002\/1097-0142(197706)39:6<2608::AID-CNCR2820390646>3.0.CO;2-B","volume":"39","author":"Lyon","year":"1977","unstructured":"Lyon JL, Gardner JW, Klauber M et al. (1977) Low cancer incidence and mortality in Utah. Cancer 39: 2608","journal-title":"Cancer"},{"key":"1075_CR52","first-page":"1055","volume":"65","author":"Lyon","year":"1980","unstructured":"Lyon JL, Gardner JW, West DW (1980) Cancer incidence in Mormons and non-Mormons in Utah during 1967--75. J Nat Cancer Inst 65: 1055\u20131061","journal-title":"J Nat Cancer Inst"},{"key":"1075_CR53","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1530-0277.1986.tb05117.x","volume":"10","author":"Maier","year":"1988","unstructured":"Maier H, Born IA, Veith Set al. (1988) The effect of ethanol consumtion on salivary gland morphology and function in the rat. Alcoholism Clin Exp Res 10: 425\u2013429","journal-title":"Alcoholism Clin Exp Res"},{"key":"1075_CR54","first-page":"320","volume":"70","author":"Maier","year":"1992","unstructured":"Maier H, Dietz A, Gewelke U et al. (1992) Tobacco and alcohol and the risk of head and neck cancer. Clin Invest 70: 320\u2013327","journal-title":"Clin Invest"},{"key":"1075_CR55","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1177\/019459989210700411","volume":"107","author":"Maier","year":"1992","unstructured":"Maier H, Gewelke U, Dietz A et al. (1992) Risk factors of cancer of the larynx: results of the Heidelberg case-control study. Otolaryngol Head Neck Surg 107: 577\u2013582","journal-title":"Otolaryngol Head Neck Surg"},{"key":"1075_CR56","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1007\/s001060050459","volume":"47","author":"Maier","year":"1999","unstructured":"Maier H, Tisch M (1999) Alkoholkonsum und Krebsrisiko im Bereich des oberen Verdauungstrakts. HNO 47: 764\u2013765","journal-title":"HNO"},{"key":"1075_CR57","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1530-0277.1994.tb00030.x","volume":"18","author":"Maier","year":"1994","unstructured":"Maier H, Weidauer H, Z\u00f6ller J et al. (1994) The effect of chronic ethanol consumtion on the morphology of the oral mucosa. Alcoholism Clin Exp Res 18: 387\u2013391","journal-title":"Alcoholism Clin Exp Res"},{"key":"1075_CR58","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1177\/019459989310800606","volume":"108","author":"Maier","year":"1993","unstructured":"Maier H, Z\u00f6ller J, Herrmann A et al. (1993) Dental status and oral hygiene in patients with head and neck cancer. Otolaryngol Head Neck Surg 108: 655\u2013661","journal-title":"Otolaryngol Head Neck Surg"},{"key":"1075_CR59","doi-asserted-by":"crossref","first-page":"369","DOI":"10.14219\/jada.archive.1971.0043","volume":"82","author":"Mandel","year":"1971","unstructured":"Mandel L, Baurmash H (1971) Parotid enlargement due to alcoholism. J Am Dent Ass 82: 369\u2013373","journal-title":"J Am Dent Ass"},{"key":"1075_CR60","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1136\/bmj.1.6162.546","volume":"24","author":"Marshall","year":"1979","unstructured":"Marshall AM, Wright AL (1979) Action on alcohol. Br Med J 24: 546","journal-title":"Br Med J"},{"key":"1075_CR61","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1055\/s-0028-1107777","volume":"99","author":"Martini","year":"1974","unstructured":"Martini GA, Wienbeck M (1974) Does alcohol favour the development of Barret\u2019s syndrome (endobrachy-oesophagus)? Dtsch Med Wochenschr 99: 434\u2013439","journal-title":"Dtsch Med Wochenschr"},{"key":"1075_CR62","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0232-1513(84)80033-X","volume":"25","author":"Mascres","year":"1984","unstructured":"Mascres C, Ming-Wen F, Joly JG (1984) Morphologic changes of the esophageal mucosa in the rat after chronic alcohol ingestion. Exp Pathol 25: 147\u2013153","journal-title":"Exp Pathol"},{"key":"1075_CR63","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1002\/1097-0142(19930815)72:4<1369::AID-CNCR2820720436>3.0.CO;2-L","volume":"72","author":"Mashberg","year":"1993","unstructured":"Mashberg A, Boffetta P, Winkelman R et al. (1993) Tobacco smoking, alcohol drinking, and cancer of the oral cavity and oropharynx among U.S. veterans. Cancer 72: 1369\u20131375","journal-title":"Cancer"},{"key":"1075_CR64","doi-asserted-by":"crossref","first-page":"146","DOI":"10.3322\/canjclin.31.3.146","volume":"31","author":"Mashberg","year":"1981","unstructured":"Mashberg A, Garfinkel L, Harris S (1981) Alcohol as a primary risk factor in oral squamous carcinoma. Can Cancer J Clin 31: 146\u2013155","journal-title":"Can Cancer J Clin"},{"key":"1075_CR65","first-page":"193","volume":"5","author":"Maurer","year":"1997","unstructured":"Maurer JT, H\u00f6rmann K (1997): Stellung der Hals-Nasen-Ohrenheilkunde in der Schlafmedizin. HNO Aktuell 5: 193\u2013198","journal-title":"HNO Aktuell"},{"key":"1075_CR66","first-page":"2849","volume":"41","author":"McCoy","year":"1981","unstructured":"McCoy GD, Hecht SS, Katayama S et al. (1981) Differential effect of chronic ethanol consumption on the carcinogenicity of N-nitrosopyrrolidine and N\u2019-nitrosonornicotine in male Syrian golden hamsters. Cancer Res 41: 2849\u20132854","journal-title":"Cancer Res"},{"key":"1075_CR67","first-page":"131","volume":"32","author":"Mincis","year":"1995","unstructured":"Mincis M, Chebli JM, Khouri ST, Mincis R (1995) Ethanol and the gastrointestinal tract. Arq Gastroenterol 32: 131\u2013139","journal-title":"Arq Gastroenterol"},{"key":"1075_CR68","first-page":"role","volume":"washings","author":"Miyakawa","year":"1996","unstructured":"Miyakawa H, Baraona E, Chang Jc et al. (1996) Oxidation of ethanol to acetaldehyde by bronchopulmonary washings: role of bacteria. Alcohol Clin Exp Res 10, 517\u2013520","journal-title":"Oxidation of ethanol to acetaldehyde by bronchopulmonary"},{"key":"1075_CR69","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0232-1513(83)80030-9","volume":"24","author":"Muller","year":"1983","unstructured":"Muller P, Hepke B, Meldau U et al. (1983) Tissue damage in the rabbit oral mucosa by acute and chronic direct toxic action of different alcohol concentrations. Exp Pathol 24: 171\u2013181","journal-title":"Exp Pathol"},{"key":"1075_CR70","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0165-1161(81)90223-5","volume":"85","author":"Nishioka","year":"1981","unstructured":"Nishioka H, Nishi K, Kyokane K (1981) Human saliva inactivates mutagenicity of carcinogens. Mutation Res 85: 323\u2013333","journal-title":"Mutation Res"},{"key":"1075_CR71","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0165-1110(87)90003-0","volume":"186","author":"Obe","year":"1987","unstructured":"Obe G, Anderson D (1987) International Commission for Protection against Environmental Mutagens and Carcinogens. ICPEMC Working Paper No. 15\/1. Genetic effects of ethanol. Mutation Res 186: 177\u2013200","journal-title":"Mutation Res"},{"key":"1075_CR72","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0165-7992(86)90075-8","volume":"174","author":"Obe","year":"1986","unstructured":"Obe G, Jonas R, Schmidt S (1986) Metabolism of ethanol in vitro produces a compound which induces sister-chromatid exchanges in human peripheral lymphocytes in vitro: acetaldehyde not ethanol is mutagenic. Mutation Res 174: 47\u201351","journal-title":"Mutation Res"},{"key":"1075_CR73","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0165-1110(79)90004-6","volume":"65","author":"Obe","year":"1979","unstructured":"Obe G, Ristow H (1979) Mutagenic, cancerogenic and teratogenic effects of alcohol. Mutation Res 65: 229\u2013259","journal-title":"Mutation Res"},{"key":"1075_CR74","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0266-4356(98)90707-0","volume":"36","author":"Ogden","year":"1998","unstructured":"Ogden GR, Wight AJ (1998) Aetiology of oral cancer: alcohol. Br J Oral Maxillofacial Surg 36: 247\u2013251","journal-title":"Br J Oral Maxillofacial Surg"},{"key":"1075_CR75","first-page":"631","volume":"97","author":"Pikkarainen","year":"1981","unstructured":"Pikkarainen PH, Baraona E, Jauhonen P et al. (1981) Contribution of oropharynx flora and of lung microsomes to acetaldehyde in expired air after alcohol ingestion. J Lab Clin Med 97: 631\u2013636","journal-title":"J Lab Clin Med"},{"key":"1075_CR76","doi-asserted-by":"crossref","unstructured":"Rehm J (2002). Alkoholkonsum und Gesamtmortalit\u00e4t und Morbidit\u00e4t\u2014Gibt es positive Auswirkungen eines moderaten regelm\u00e4\u00dfigen Alkoholkonsums? In: Singer MV, Teyssen S: Kompendium Alkohol. Folgeerkrankungen\u2014Klinik\u2014Diagnostik\u2014Therapie, Kap\u00a029. Springer, Berlin Heidelberg New York Tokio","DOI":"10.1007\/978-3-642-56253-2_29"},{"key":"1075_CR77","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1164\/arrd.1984.130.2.153","volume":"130","author":"Remmers","year":"1989","unstructured":"Remmers JE (1989) Obstructive sleep apnoe. A common disorder exacerbated by alcohol. Am Rev Respir Dis 130: 153\u2013155","journal-title":"Am Rev Respir Dis"},{"key":"1075_CR78","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/S1521-6918(03)00019-2","volume":"17","author":"Riedel","year":"2003","unstructured":"Riedel F, Goessler U, Hormann K (2003) Alcohol-related diseases of the mouth and throat. Best Pract Res Clin Gastroenterol 17: 543\u2013555","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"1075_CR79","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/0021-9681(72)90006-9","volume":"25","author":"Rothman","year":"1972","unstructured":"Rothman K, Keller A (1972) The effect of joint exposure to alcohol and tobacco on risk of cancer of the mouth and pharynx. J Chron Dis 25: 711\u2013716","journal-title":"J Chron Dis"},{"key":"1075_CR80","doi-asserted-by":"crossref","first-page":"137S","DOI":"10.1111\/j.1530-0277.2001.tb02388.x","volume":"25","author":"Seitz","year":"2001","unstructured":"Seitz HK, Matsuzaki S, Yokoyama A, et al. (2001) Alcohol and cancer. Alcoholism Clin Exp Res 25: 137S-143S","journal-title":"Alcoholism Clin Exp Res"},{"key":"1075_CR81","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0741-8329(94)00091-3","volume":"12","author":"Simanowski","year":"1995","unstructured":"Simanowski UA, Stickel F, Maier H et al. (1995) Effect of alcohol on gastrointestinal cell regeneration as a possible mechanism in alcohol-associated carcinogenesis. Alcohol 12: 111\u2013115","journal-title":"Alcohol"},{"key":"1075_CR82","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1600-0714.1986.tb00623.x","volume":"15","author":"Squier","year":"1986","unstructured":"Squier CA, Cox P, Hall BK (1986) Enhanced penetration of nitrosonornicotine across oral mucosa in the presence of ethanol. J Oral Pathol 15: 276\u2013279","journal-title":"J Oral Pathol"},{"key":"1075_CR83","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0165-1161(82)90027-9","volume":"97","author":"Stich","year":"1982","unstructured":"Stich HF, Rosin MP, Bryson L (1982) The inhibitory effect of whole and deproteinized saliva on mutagenicity and clastogenicity resulting from a model nitrosation reaction. Mutation Res 97: 283\u2013292","journal-title":"Mutation Res"},{"key":"1075_CR84","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/0002-9343(81)90124-8","volume":"71","author":"Taasan","year":"1981","unstructured":"Taasan VC, Block AJ, Boysen PG, WynneW (1981): Alcohol increases sleep apnea and oxygen desaturation in asymptomatic man. Am J Med 71: 240\u2013245","journal-title":"Am J Med"},{"key":"1075_CR85","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/ijc.2910460310","volume":"46","author":"Talamini","year":"1990","unstructured":"Talamini R, Franceschi S, Barra S et al. (1990) The role of alcohol in oral and pharyngeal cancer in non-smokers, and of tobacco in non-drinkers. Int J Cancer 46: 391\u2013393","journal-title":"Int J Cancer"},{"key":"1075_CR86","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0165-1218(80)90076-2","volume":"79","author":"Tates","year":"1980","unstructured":"Tates AD, de Vogel N, Neuteboom I (1980) Cytogenetic effects in hepatocytes, bone-marrow cells and blood lymphocytes of rats exposed to ethanol in the drinking water. Mutation Res 79: 285\u2013288","journal-title":"Mutation Res"},{"key":"1075_CR87","doi-asserted-by":"crossref","unstructured":"Teschke R (2002) Alkohol und Krebs. In: Singer MV, Teyssen S: Kompendium Alkohol. Folgeerkrankungen\u2014Klinik\u2014Diagnostik\u2014Therapie, Kap\u00a019. Springer, Berlin Heidelberg New York Tokio","DOI":"10.1007\/978-3-642-56253-2_19"},{"key":"1075_CR88","first-page":"2840","volume":"39","author":"Tuyns","year":"1979","unstructured":"Tuyns A (1979) Epidemiology of alcohol and cancer. Cancer Res 39: 2840\u20132843","journal-title":"Cancer Res"},{"key":"1075_CR89","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/ijc.2910410403","volume":"41","author":"Tuyns","year":"1988","unstructured":"Tuyns AJ, Esteve J, Raymond L et al. (1988) Cancer of the larynx\/hypopharynx, tobacco and alcohol: IARC international case-control study in Turin and Varese (Italy), Zaragoza and Navarra (Spain), Geneva (Switzerland) and Calvados (France). Int J Cancer 41: 483\u2013491","journal-title":"Int J Cancer"},{"key":"1075_CR90","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1111\/j.1600-0714.1985.tb00543.x","volume":"14","author":"Valentine","year":"1985","unstructured":"Valentine JA, Scott J, West CR, et al. (1985) A histological analysis of the early effects of alcohol and tobacco usage on human lingual epithelium. J Oral Pathol 14: 654\u2013665","journal-title":"J Oral Pathol"},{"key":"1075_CR91","doi-asserted-by":"crossref","unstructured":"Van Haaren MRT, Hendriks HFJ (2002) Alkoholstoffwechsel. In: Singer MV, Teyssen S: Kompendium Alkohol. Folgeerkrankungen\u2014Klinik\u2014Diagnostik\u2014Therapie,Kap\u00a04. Springer, Berlin Heidelberg New York Tokio","DOI":"10.1007\/978-3-642-56253-2_4"},{"key":"1075_CR92","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S1368-8375(98)00022-0","volume":"34","author":"Wight","year":"1998","unstructured":"Wight AJ, Ogden GR (1998) Possible mechanisms by which alcohol may influence the development of oral cancer--a review. Oral Oncol 34: 441\u2013447","journal-title":"Oral Oncol"},{"key":"1075_CR93","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1002\/1097-0142(195909\/10)12:5<1016::AID-CNCR2820120523>3.0.CO;2-2","volume":"12","author":"Wynder","year":"1959","unstructured":"Wynder EL, Lemon FR, Bross IJ (1959) Cancer and coronary artery disease among Seventh day Adventists. Cancer 12: 1016\u20131028","journal-title":"Cancer"},{"key":"1075_CR94","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1002\/1097-0142(195711\/12)10:6<1300::AID-CNCR2820100628>3.0.CO;2-2","volume":"16","author":"Wynder","year":"1957","unstructured":"Wynder EL; Bross IJ, Feldman R (1957) A study of the the ethiology factors in cancer of the mouth. Cancer 16: 1300\u20131323","journal-title":"Cancer"},{"key":"1075_CR95","first-page":"99","volume":"5","author":"Yokoyama","year":"1996","unstructured":"Yokoyama A, Muramatsu T, Ohmori Tet al. (1996) Esophageal cancer and aldehyde dehydrogenase-2 genotypes in Japanese males. Cancer Epidemiology Biomarkers Prevention 5: 99\u2013102","journal-title":"Cancer Epidemiology Biomarkers Prevention"},{"key":"1075_CR96","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1093\/carcin\/19.8.1383","volume":"19","author":"Yokoyama","year":"1998","unstructured":"Yokoyama A, Muramatsu T, Ohmori T et al. (1998) Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics. Carcinogenesis 19: 1383\u20131387","journal-title":"Carcinogenesis"},{"key":"1075_CR97","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1002\/(SICI)1097-0142(19960515)77:10<1986::AID-CNCR4>3.0.CO;2-F","volume":"77","author":"Yokoyama","year":"1996","unstructured":"Yokoyama A, Muramutsu T, Ohmori T et al. (1996) Multiple primary esophageal and concurrent upper aerodigestive tract cancer and the aldehyde dehydrogenase type-2 genotype of Japanese alcoholics. Cancer 77: 1986\u20131990","journal-title":"Cancer"},{"key":"1075_CR98","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/(SICI)1097-0215(19961104)68:3<313::AID-IJC8>3.0.CO;2-4","volume":"68","author":"Yokoyama","year":"1996","unstructured":"Yokoyama A, Ohmori T, Muramatsu T et al. (1996) Cancer screening of upper aerodigestive tract in Japanese alcoholics with reference to drinking and smoking habits and aldehyde dehydrogenase-2. Int J Cancer 68: 313\u2013316","journal-title":"Int J Cancer"}],"container-title":["HNO"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00106-004-1075-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00106-004-1075-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00106-004-1075-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T19:20:42Z","timestamp":1585682442000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00106-004-1075-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,7]]},"references-count":98,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["1075"],"URL":"https:\/\/doi.org\/10.1007\/s00106-004-1075-3","relation":{},"ISSN":["0017-6192","1433-0458"],"issn-type":[{"value":"0017-6192","type":"print"},{"value":"1433-0458","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,7]]}}}