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The authors report their experience with the surgical management of tumors with rare transmodiolar or transmacular extension and outcomes after cochlear implantation (CI).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This retrospective case series included nine patients with either primary intralabyrinthine tumors or secondary invasion of the inner ear from the internal auditory canal. The primary endpoint with CI, performed in six patients, was word recognition score at 65\u202fdB SPL (sound pressure level). Secondary endpoints were intra- and postoperative electrophysiological parameters, impedance measures, the presence of a\u00a0wave\u00a0V in the electrically evoked (via the CI) auditory brainstem responses, the specifics of postoperative CI programming, and adverse events.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Hearing rehabilitation with CI in cases of transmodiolar tumor growth could be achieved only with incomplete tumor removal, whereas tumors with transmacular growth could be completely removed. All six patients with CI had good word recognition scores for numbers in quiet conditions (80\u2013100% at 65\u202fdB SPL, not later than 6 to 12\u00a0months post CI activation). Four of these six patients achieved good to very good results for monosyllabic words within 1\u201336\u00a0months (65\u201385% at 65\u202fdB SPL). The two other patients, however, had low scores for monosyllables at 6\u00a0months (25 and 15% at 65\u202fdB SPL, respectively) with worsening of results thereafter.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Cochleovestibular schwannomas with transmodiolar and transmacular extension represent a\u00a0rare entity with specific management requirements. Hearing rehabilitation with CI is a\u00a0principal option in these patients.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00106-020-00919-9","type":"journal-article","created":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T14:02:43Z","timestamp":1602511363000},"page":"7-19","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Management of transmodiolar and transmacular cochleovestibular schwannomas with and without cochlear implantation","Management transmodiol\u00e4rer und transmakul\u00e4rer Vestibularis- und Cochlearisschwannome mit und ohne Cochleaimplantation"],"prefix":"10.1007","volume":"69","author":[{"given":"S. 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V.; Merck Serono; Infectopharm; Dr.Willmar Schwabe GmbH & Co. KG, Germany (lecture fees and travel reimbursement); P.\u00a0Caye-Thomasen: Oticon Medical, Denmark; Cochlear Ltd., Australia (research projects); T.\u00a0Rahne: Oticon Medical, Denmark; Cochlear Ltd., Australia (research projects), MED-EL Austria and MED-EL Germany (travel reimbursement for speaking engagement); G.\u00a0G\u00f6tze: MED-EL Austria und MED-EL Germany (research projects, travel reimbursement for speaking engagement). C.\u00a0Strauss, S.\u00a0K\u00f6sling, U.\u00a0Siebolts, D.\u00a0Vordermark, L.\u00a0Wagner and L.\u00a0Fr\u00f6hlich declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants or on human tissue were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1975 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study. Additional written informed consent was obtained from all individual participants or their legal representatives for whom identifying information is included in this article.The supplement containing this article is not sponsored by industry.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}