{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T22:30:13Z","timestamp":1768084213227,"version":"3.49.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T00:00:00Z","timestamp":1600041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T00:00:00Z","timestamp":1600041600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["HNO"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n                <jats:title>Hintergrund<\/jats:title>\n                <jats:p>Die Epistaxis  ist ein h\u00e4ufiges Symptom in der Arztpraxis   und assoziiert mit verschiedenen Komorbidit\u00e4ten und Medikamenten, insbesondere Antikoagulanzien. Trotz ihrer Allt\u00e4glichkeit gibt es nur wenige Daten zur H\u00e4ufigkeit ihres Auftretens und m\u00f6glichen Risikofaktoren.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methoden<\/jats:title>\n                <jats:p>Die Studie untersuchte anhand einer gro\u00dfen Patientenpopulation (AOK Niedersachsen) \u00fcber 10 Jahre (2007\u20132016) die Versorgung von Epistaxis in Niedersachsen. Alter bei Diagnose, Begleitmedikation und Komorbidit\u00e4ten wurden analysiert und die Pr\u00e4valenz  dargestellt.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>162.167 Versicherte der AOK Niedersachen wurden zwischen 2007 und 2016 aufgrund einer Epistaxis in 308.947 F\u00e4llen \u00e4rztlich vorstellig. Die meisten Patienten wurden ausschlie\u00dflich ambulant behandelt (96,6\u202f%). \u00dcber den Studienzeitraum stieg die  Pr\u00e4valenz um 21\u202f% (Anstieg von 8,7 auf 9,3 pro 1000 Versicherte\/Jahr) bei  stabiler Pr\u00e4valenz f\u00fcr station\u00e4re Vorstellungen (0,2 pro 1000 Versicherte\/Jahr). Die h\u00f6chsten Pr\u00e4valenzen fanden sich bei Personen bis 20\u00a0und \u00fcber 80\u00a0Jahre. In  17,5\u202f% aller Epistaxisf\u00e4lle wurden Antithrombotika erfasst (9,5\u202f% orale Antikoagulanzien). \u00dcber den Studienzeitraum konnte eine erh\u00f6hte Verschreibung von Antikoagulanzien (7,7\u202f% in 2007 auf 11,8\u202f% in 2016, insbesondere NOAK) dokumentiert werden.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Schlussfolgerung<\/jats:title>\n                <jats:p>Neben der arteriellen Hypertonie, dem m\u00e4nnlichen Geschlecht sowie der typischen Altersverteilung  bestand auch h\u00e4ufig eine Medikation mit Antikoagulanzien. \u00dcber den untersuchten Zeitraum zeigte  sich eine Zunahme von Epistaxisf\u00e4llen bei gleichzeitig ansteigender Verschreibungsh\u00e4ufigkeit von NOAK, nicht jedoch von schweren hospitalisationsbed\u00fcrftigen Epistaxisf\u00e4llen. Eine abschlie\u00dfende Beurteilung hinsichtlich eines m\u00f6glichen kausalen Zusammenhangs  muss in weiteren Studien untersucht werden.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00106-020-00940-y","type":"journal-article","created":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T23:19:48Z","timestamp":1600125588000},"page":"206-212","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Epistaxis und antithrombotische Medikation: eine Analyse der Daten einer gesetzlichen Krankenversicherung in Niedersachsen","Epistaxis and anticoagulation therapy: an analysis based on health insurance data from Lower Saxony"],"prefix":"10.1007","volume":"69","author":[{"given":"A. 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H.","family":"Freitag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Jobski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"D\u00f6rks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,9,14]]},"reference":[{"issue":"3","key":"940_CR1","first-page":"129","volume":"13","author":"B Petruson","year":"1975","unstructured":"Petruson\u00a0B, Rudin\u00a0R (1975) The frequency of epistaxis in a\u00a0male population sample. Rhinology 13(3):129\u2013133","journal-title":"Rhinology"},{"issue":"955","key":"940_CR2","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1136\/pgmj.2004.025007","volume":"81","author":"LE Pope","year":"2005","unstructured":"Pope\u00a0LE, Hobbs\u00a0CG (2005) Epistaxis: an update on current management. 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