{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:13:32Z","timestamp":1786979612455,"version":"build-2736575974"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2020,11,13]],"date-time":"2020-11-13T00:00:00Z","timestamp":1605225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,11,13]],"date-time":"2020-11-13T00:00:00Z","timestamp":1605225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001652","name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001652","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["HNO"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Hintergrund<\/jats:title>\n                    <jats:p>Tinnitus betrifft ca.\u00a015\u202f% der Bev\u00f6lkerung, jedoch existiert noch immer kein echtes Heilverfahren. Ein von uns entwickeltes neuartiges Erkl\u00e4rungsmodell erlaubt nun die Erprobung einer gezielten, an den Ursachen der Tinnitusentstehung ansetzenden Behandlung. Diese basiert auf stochastischen Resonanzph\u00e4nomenen an bestimmten synaptischen Verbindungen im H\u00f6rsystem, welche gezielt durch extern zugef\u00fchrtes schwellennahes Rauschen induziert werden sollen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Fragestellung<\/jats:title>\n                    <jats:p>Die vorliegende Pilotstudie soll zeigen, ob ein spektral individuell angepasstes Rauschen erfolgreich chronischen tonalen\/schmalbandigen Tinnitus w\u00e4hrend der Stimulation abschw\u00e4chen kann.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material und Methoden<\/jats:title>\n                    <jats:p>Bei 22\u00a0vollj\u00e4hrigen Tinnituspatienten (46.6\u00b116.3\u00a0Jahre; 4\u00a0Frauen) wurden H\u00f6rverlust (HV) sowie Tinnitusfrequenzen (TF) und -lautst\u00e4rken (TL) audiometrisch bestimmt. Darauf basierend wurden bis zu 8\u00a0verschiedene Rauschstimuli (RS) mit je 5\u00a0Lautst\u00e4rken (\u221220 bis +20\u202fdB SL) erzeugt. Diese wurden \u00fcber audiologische Kopfh\u00f6rer in einer Schallkammer f\u00fcr jeweils 40\u202fs pr\u00e4sentiert. Nach jeder Pr\u00e4sentation wurde mithilfe einer 5\u2011stufigen Bewertungsskala (\u22122 bis +2) ermittelt, ob sich die TL ver\u00e4ndert hat.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ergebnisse<\/jats:title>\n                    <jats:p>\n                      Es fanden sich Patienten ohne Verbesserung der TL (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u20096) und solche mit Verbesserung (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u200916), wobei hier RS um die TF besonders effektiv waren. Die Gruppen zeigten post hoc deutliche Unterschiede in den Audiogrammen: Offenbar ist das hier getestete Verfahren insbesondere bei normalh\u00f6renden Tinnituspatienten und solchen mit geringgradigem HV effektiv.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Schlussfolgerung<\/jats:title>\n                    <jats:p>Die subjektiv wahrgenommene TL war bei 16\u00a0von 22\u00a0Probanden f\u00fcr die Dauer der Stimulation reduziert. F\u00fcr den m\u00f6glichen Erfolg einer zuk\u00fcnftigen Therapie scheint der HV relevant zu sein.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00106-020-00963-5","type":"journal-article","created":{"date-parts":[[2020,11,13]],"date-time":"2020-11-13T10:02:38Z","timestamp":1605261758000},"page":"891-898","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Reduktion der Tinnituslautst\u00e4rke","Reducing tinnitus intensity"],"prefix":"10.1007","volume":"69","author":[{"given":"A.","family":"Schilling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Krauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Hannemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Schulze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Tziridis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,11,13]]},"reference":[{"key":"963_CR1","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.nicl.2017.05.017","volume":"15","author":"I Adamchic","year":"2017","unstructured":"Adamchic\u00a0I, Toth\u00a0T, Hauptmann\u00a0C et al (2017) Acute effects and after-effects of acoustic coordinated reset neuromodulation in patients with chronic subjective tinnitus. 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Von allen beteiligten Patienten liegt eine Einverst\u00e4ndniserkl\u00e4rung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}