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Die h\u00e4ufig vorkommenden Karzinome sollten hinreichend sicher operativ entfernt und gleichsam funktionelle Strukturen zuverl\u00e4ssig gesch\u00fctzt werden. Insbesondere der Erhalt neuronaler Strukturen bei gleichzeitiger Tumorkontrolle l\u00e4sst einzeitige Konzepte zweckdienlich erscheinen, wenngleich diese nicht hinreichend etabliert sind. Ziel der Studie war die Beurteilung der intraoperativen Schnellschnittdiagnostik als m\u00f6gliche Grundlage eines einzeitigen chirurgischen Therapiekonzepts und somit die Verhinderung funktioneller Alterationen durch Reoperationen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methoden<\/jats:title>\n                    <jats:p>Es wurden 114 konsekutive Patient*innen in die Studie eingeschlossen, bei denen nach der HNO-Spiegeluntersuchung und bildgebender Diagnostik die Artigkeit der L\u00e4sion nicht zugeordnet werden konnte. Patient*innen mit bekanntem Karzinom in der Vorgeschichte oder Hinweis auf eine akut entz\u00fcndliche\/karzinogene Prim\u00e4rl\u00e4sion in der HNO- und\/oder bildgebenden Untersuchung wurden ausgeschlossen. Es wurde eine intraoperative Schnellschnittdiagnostik mit der Fragestellung nach Vorliegen eines Karzinoms durchgef\u00fchrt. Patient*innenbezogene Daten sowie die Zuverl\u00e4ssigkeit des Schnellschnittergebnisses wurden vergleichend erfasst.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ergebnisse<\/jats:title>\n                    <jats:p>Bei insgesamt 114\u00a0Patient*innen wurde ein intraoperativer Schnellschnitt durchgef\u00fchrt. Karzinome wurden mit einer Sensitivit\u00e4t von 87\u202f% und einer Spezifit\u00e4t von 100\u202f% diagnostiziert. Die durchgef\u00fchrte Diagnostik h\u00e4tte somit dazu gef\u00fchrt, dass in einem einzeitigen Konzept kein Patient unn\u00f6tig radikal operiert worden w\u00e4re. Bei 26 von 30\u00a0Patient*innen h\u00e4tte ein Zweiteingriff vermieden werden k\u00f6nnen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Schlussfolgerung<\/jats:title>\n                    <jats:p>Die intraoperative Schnellschnittdiagnostik stellt potenziell eine wichtige Methode dar, um Karzinome histologisch zu best\u00e4tigen und zweizeitige Vorgehen zu vermeiden. Das Fehlen falsch-positiver Befunde h\u00e4tte ein unerw\u00fcnscht radikales Vorgehen bei 100\u202f% der Patient*innen verhindert.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00106-022-01240-3","type":"journal-article","created":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T14:05:06Z","timestamp":1668434706000},"page":"164-169","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Schnellschnittdiagnostik bei Tumoren des Trigonum submandibulare","Frozen section biopsy for tumors of the submandibular triangle"],"prefix":"10.1007","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0760-9794","authenticated-orcid":false,"given":"S.","family":"Riemann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Knopf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,14]]},"reference":[{"key":"1240_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2019.12.026","author":"S Atallah","year":"2020","unstructured":"Atallah\u00a0S, Moya-Plana\u00a0A, Malard\u00a0O et al (2020) Should a\u00a0neck dissection be performed on patients with cN0 adenoid cystic carcinoma? 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