{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T00:12:07Z","timestamp":1719015127269},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T00:00:00Z","timestamp":1708905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T00:00:00Z","timestamp":1708905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["HNO"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1007\/s00106-024-01431-0","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T17:02:12Z","timestamp":1708966932000},"page":"484-493","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hat die ASS-Desaktivierung in Zeiten von Biologika noch einen Stellenwert bei chronischer Rhinosinusitis mit nasaler Polyposis?","Does aspirin therapy after desensitization still have a role in treatment of chronic rhinosinusitis with nasal polyposis in the era of biologics?"],"prefix":"10.1007","volume":"72","author":[{"given":"F.","family":"Klimek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"F\u00f6rster-Ruhrmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Hagemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Cuevas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Gr\u00f6ger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Klimek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,2,26]]},"reference":[{"issue":"4","key":"1431_CR1","first-page":"241","volume":"6","author":"AA White","year":"2020","unstructured":"White\u00a0AA, Woessner\u00a0K, Simon\u00a0R (2020) Aspirin-exacerbated respiratory disease: update on medical management. Head Neck Surg 6(4):241\u2013247","journal-title":"Head Neck Surg"},{"issue":"3","key":"1431_CR2","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1034\/j.1399-3003.2000.016003432.x","volume":"16","author":"A Szczeklik","year":"2000","unstructured":"Szczeklik\u00a0A, Nizankowska\u00a0E, Duplaga\u00a0M (2000) Natural history of aspirin-induced asthma. AIANE investigators. European network on aspirin-induced asthma. Eur Respir\u00a0J 16(3):432\u2013436","journal-title":"Eur Respir J"},{"issue":"1","key":"1431_CR3","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1111\/all.13599","volume":"74","author":"ML Kowalski","year":"2019","unstructured":"Kowalski\u00a0ML et\u00a0al (2019) Diagnosis and management of NSAID-exacerbated respiratory disease (N-ERD)-a EAACI position paper. Allergy 74(1):28\u201339","journal-title":"Allergy"},{"key":"1431_CR4","first-page":"889221","volume":"3","author":"L De Prins","year":"2022","unstructured":"De Prins\u00a0L et\u00a0al (2022) White paper on European patient needs and suggestions on chronic type\u00a02 inflammation of airways and skin by EUFOREA. Allergy 3:889221","journal-title":"Allergy"},{"issue":"7","key":"1431_CR5","first-page":"506","volume":"51","author":"T Mewes","year":"1996","unstructured":"Mewes\u00a0T, Riechelmann\u00a0H, Klimek\u00a0L (1996) Increased in vitro cysteinyl leukotriene release from blood leukocytes in patients with asthma, nasal polyps, and aspirin intolerance. Allergy 51(7):506\u2013510","journal-title":"Allergy"},{"issue":"4","key":"1431_CR6","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/S0272-5231(21)00582-7","volume":"9","author":"HJ Zeitz","year":"1988","unstructured":"Zeitz\u00a0HJ (1988) Bronchial asthma, nasal polyps, and aspirin sensitivity: samter\u2019s syndrome. Clin Chest Med 9(4):567\u2013576","journal-title":"Clin Chest Med"},{"issue":"4","key":"1431_CR7","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1093\/ije\/28.4.717","volume":"28","author":"J Hedman","year":"1999","unstructured":"Hedman\u00a0J et\u00a0al (1999) Prevalence of asthma, aspirin intolerance, nasal polyposis and chronic obstructive pulmonary disease in a\u00a0population-based study. Int J Epidemiol 28(4):717\u2013722","journal-title":"Int J Epidemiol"},{"issue":"1","key":"1431_CR8","first-page":"53","volume":"79","author":"W Hosemann","year":"2000","unstructured":"Hosemann\u00a0W, K\u00fchnel\u00a0T, Pfeifer\u00a0M (2000) Analgetikaintoleranz und Polyposis nasi. Laryngo- Rhino-otologie 79(1):53\u201365","journal-title":"Laryngo- Rhino-otologie"},{"issue":"3","key":"1431_CR9","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/j.jaci.2014.08.020","volume":"135","author":"JP Rajan","year":"2015","unstructured":"Rajan\u00a0JP et\u00a0al (2015) Prevalence of aspirin-exacerbated respiratory disease among asthmatic patients: a\u00a0meta-analysis of the literature. J\u00a0Allergy Clin Immunol 135(3):676\u2013681.e1","journal-title":"J Allergy Clin Immunol"},{"issue":"Suppl S29","key":"1431_CR10","first-page":"1","volume":"58","author":"WJ Fokkens","year":"2020","unstructured":"Fokkens\u00a0WJ et\u00a0al (2020) European position paper on rhinosinusitis and nasal polyps 2020. Rhinology 58(Suppl S29):1\u2013464","journal-title":"Rhinology"},{"issue":"3","key":"1431_CR11","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1016\/j.jaci.2020.10.043","volume":"147","author":"WW Stevens","year":"2020","unstructured":"Stevens\u00a0WW et\u00a0al (2020) The role of aspirin desensitization followed by oral aspirin therapy in managing patients with aspirin-exacerbated respiratory disease: A\u00a0Work Group Report from the Rhinitis, Rhinosinusitis and Ocular Allergy Committee of the American Academy of Allergy, Asthma & Immunology. J\u00a0Allergy Clin Immunol 147(3):827\u2013844","journal-title":"J Allergy Clin Immunol"},{"issue":"5949","key":"1431_CR12","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1136\/bmj.1.5949.67","volume":"1","author":"A Szczeklik","year":"1975","unstructured":"Szczeklik\u00a0A, Gryglewski\u00a0RJ, Czerniawska-Mysik\u00a0G (1975) Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. BMJ 1(5949):67\u201369","journal-title":"BMJ"},{"key":"1431_CR13","doi-asserted-by":"publisher","first-page":"147326","DOI":"10.1016\/j.gene.2023.147326","volume":"870","author":"A Fathollahpour","year":"2023","unstructured":"Fathollahpour\u00a0A et\u00a0al (2023) Aspirin-exacerbated respiratory disease polymorphisms; a\u00a0review study. Gene 870:147326","journal-title":"Gene"},{"issue":"5","key":"1431_CR14","doi-asserted-by":"publisher","first-page":"1449","DOI":"10.1016\/j.jaci.2015.12.1324","volume":"137","author":"P Tomassen","year":"2016","unstructured":"Tomassen\u00a0P et\u00a0al (2016) Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers. J\u00a0Allergy Clin Immunol 137(5):1449\u20131456.e4","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"1431_CR15","first-page":"151","volume":"59","author":"PW Hellings","year":"2021","unstructured":"Hellings\u00a0PW, Verhoeven\u00a0E, Fokkens\u00a0WJ (2021) State-of-the-art overview on biological treatment for CRSwNP. Rhinology 59(2):151\u2013163","journal-title":"Rhinology"},{"key":"1431_CR16","first-page":"2023","volume-title":"S2k-Leitlinie zur fach\u00e4rztlichen Diagnostik und Therapie von Asthma","author":"M Lommatzsch","year":"2023","unstructured":"Lommatzsch\u00a0M et\u00a0al (2023) S2k-Leitlinie zur fach\u00e4rztlichen Diagnostik und Therapie von Asthma. Pneumologie, Stuttgart, Germany, S\u00a02023"},{"issue":"11","key":"1431_CR17","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1056\/NEJMra1712125","volume":"379","author":"AA White","year":"2018","unstructured":"White\u00a0AA, Stevenson\u00a0DD (2018) Aspirin-exacerbated respiratory disease. N\u00a0Engl J Med 379(11):1060\u20131070","journal-title":"N Engl J Med"},{"issue":"4","key":"1431_CR18","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1016\/S0091-6749(96)70123-9","volume":"98","author":"DD Stevenson","year":"1996","unstructured":"Stevenson\u00a0DD et\u00a0al (1996) Aspirin desensitization treatment of aspirin-sensitive patients with rhinosinusitis-asthma: long-term outcomes. J\u00a0Allergy Clin Immunol 98(4):751\u2013758","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"1431_CR19","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/0091-6749(80)90143-8","volume":"66","author":"DD Stevenson","year":"1980","unstructured":"Stevenson\u00a0DD, Simon\u00a0RA, Mathison\u00a0DA (1980) Aspirin-sensitive asthma: tolerance to aspirin after positive oral aspirin challenges. J\u00a0Allergy Clin Immunol 66(1):82\u201388","journal-title":"J Allergy Clin Immunol"},{"issue":"5","key":"1431_CR20","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1007\/s00106-015-0008-7","volume":"63","author":"H Kirsche","year":"2015","unstructured":"Kirsche\u00a0H, Klimek\u00a0L (2015) ASS-Intoleranz-Syndrom und persistierende Rhinosinusitis : Differentialdiagnostik und Therapie. HNO 63(5):357\u2013363","journal-title":"HNO"},{"issue":"6","key":"1431_CR21","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s11882-014-0441-9","volume":"14","author":"L Klimek","year":"2014","unstructured":"Klimek\u00a0L et\u00a0al (2014) Aspirin desensitization: useful treatment for chronic rhinosinusitis with nasal polyps (CRSwNP) in aspirin-exacerbated respiratory disease (AERD)? Curr Allergy Asthma Rep 14(6):441","journal-title":"Curr Allergy Asthma Rep"},{"issue":"4","key":"1431_CR22","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1016\/j.iac.2009.07.008","volume":"29","author":"L Klimek","year":"2009","unstructured":"Klimek\u00a0L, Pfaar\u00a0O (2009) Aspirin intolerance: does desensitization alter the course of the disease? Immunol Allergy Clin North Am 29(4):669\u2013675","journal-title":"Immunol Allergy Clin North Am"},{"issue":"3","key":"1431_CR23","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1097\/01.all.0000225153.45027.6a","volume":"6","author":"O Pfaar","year":"2006","unstructured":"Pfaar\u00a0O, Klimek\u00a0L (2006) Aspirin desensitization in aspirin intolerance: update on current standards and recent improvements. Curr Opin Allergy Clin Immunol 6(3):161\u2013166","journal-title":"Curr Opin Allergy Clin Immunol"},{"issue":"5","key":"1431_CR24","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1016\/0091-6749(76)90059-2","volume":"57","author":"CR Zeiss","year":"1976","unstructured":"Zeiss\u00a0CR, Lockey\u00a0RF (1976) Refractory period to aspirin in a\u00a0patient with aspirin-induced asthma. J\u00a0Allergy Clin Immunol 57(5):440\u2013448","journal-title":"J Allergy Clin Immunol"},{"issue":"3","key":"1431_CR25","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1111\/j.1398-9995.1984.tb02621.x","volume":"39","author":"ML Kowalski","year":"1984","unstructured":"Kowalski\u00a0ML et\u00a0al (1984) Aspirin tolerance induced in aspirin-sensitive asthmatics. Allergy 39(3):171\u2013178","journal-title":"Allergy"},{"key":"1431_CR26","first-page":"734733","volume":"2","author":"A Lyly","year":"2021","unstructured":"Lyly\u00a0A, Laidlaw\u00a0TM, Lundberg\u00a0M (2021) Pathomechanisms of AERD-recent advances. Allergy 2:734733","journal-title":"Allergy"},{"issue":"8","key":"1431_CR27","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1097\/01.MLG.0000166702.38850.1B","volume":"115","author":"AA Parikh","year":"2005","unstructured":"Parikh\u00a0AA, Scadding\u00a0GK (2005) Intranasal lysine-aspirin in aspirin-sensitive nasal polyposis: a\u00a0controlled trial. Laryngoscope 115(8):1385\u20131390","journal-title":"Laryngoscope"},{"issue":"12","key":"1431_CR28","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1017\/S0022215107000515","volume":"121","author":"N Ogata","year":"2007","unstructured":"Ogata\u00a0N, Darby\u00a0Y, Scadding\u00a0G (2007) Intranasal lysine-aspirin administration decreases polyp volume in patients with aspirin-intolerant asthma. J\u00a0Laryngol Otol 121(12):1156\u20131160","journal-title":"J Laryngol Otol"},{"issue":"5","key":"1431_CR29","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1586\/1744666X.2014.901889","volume":"10","author":"A Parikh","year":"2014","unstructured":"Parikh\u00a0A, Scadding\u00a0GK (2014) Topical nasal lysine aspirin in aspirin-sensitive and aspirin-tolerant chronic rhinosinusitis with nasal polyposis. Expert Rev Clin Immunol 10(5):657\u2013665","journal-title":"Expert Rev Clin Immunol"},{"issue":"6","key":"1431_CR30","first-page":"588","volume":"67","author":"G Patriarca","year":"1991","unstructured":"Patriarca\u00a0G et\u00a0al (1991) Intranasal treatment with lysine acetylsalicylate in patients with nasal polyposis. Ann Allergy 67(6):588\u2013592","journal-title":"Ann Allergy"},{"issue":"3","key":"1431_CR31","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1159\/000027660","volume":"61","author":"J Gosepath","year":"1999","unstructured":"Gosepath\u00a0J et\u00a0al (1999) Aspirin intolerance in patients with chronic sinusitis. ORL J Oto-rhino-laryngology Its Relat Specialties 61(3):146\u2013150","journal-title":"ORL J Oto-rhino-laryngology Its Relat Specialties"},{"issue":"5","key":"1431_CR32","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1111\/all.12131","volume":"68","author":"K Fruth","year":"2013","unstructured":"Fruth\u00a0K et\u00a0al (2013) Low-dose aspirin desensitization in individuals with aspirin-exacerbated respiratory disease. Allergy 68(5):659\u2013665","journal-title":"Allergy"},{"key":"1431_CR33","doi-asserted-by":"crossref","unstructured":"Klimek L et\u00a0al (2022) Indicating biologics for chronic rhinosinusitis with nasal polyps (CRSwNP)\u2014recommendations by German allergy and ORL societies AeDA and DGHNO for dupilumab, omalizumab, and mepolizumab. Allergo J Int","DOI":"10.1007\/s40629-022-00220-x"},{"issue":"8","key":"1431_CR34","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1055\/a-1197-0136","volume":"99","author":"L Klimek","year":"2020","unstructured":"Klimek\u00a0L et\u00a0al (2020) Positionspapier: Anwendung von Biologika bei chronischer Rhinosinusitis mit Polyposis nasi (CRSwNP) im deutschen Gesundheitssystem \u2013 Empfehlungen des \u00c4rzteverbandes Deutscher Allergologen (AeDA) und der AGs Klinische Immunologie, Allergologie und Umweltmedizin und Rhinologie und Rhinochirurgie der Deutschen Gesellschaft f\u00fcr HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC). Laryngorhinootologie 99(8):511\u2013527","journal-title":"Laryngorhinootologie"},{"issue":"12","key":"1431_CR35","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1055\/a-1644-4066","volume":"100","author":"L Klimek","year":"2021","unstructured":"Klimek\u00a0L et\u00a0al (2021) Positionspapier: Empfehlungen zur Anwendung von Omalizumab bei chronischer Rhinosinusitis mit Polyposis nasi (CRSwNP) im deutschen Gesundheitssystem \u2013 Empfehlungen des \u00c4rzteverbandes Deutscher Allergologen (AeDA) und der AGs Klinische Immunologie, Allergologie und Umweltmedizin und Rhinologie und Rhinochirurgie der Deutschen Gesellschaft f\u00fcr HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC). Laryngorhinootologie 100(12):952\u2013963","journal-title":"Laryngorhinootologie"},{"issue":"4","key":"1431_CR36","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1055\/a-1752-8462","volume":"101","author":"L Klimek","year":"2022","unstructured":"Klimek\u00a0L et\u00a0al (2022) Positionspapier: Empfehlungen zur Anwendung von Mepolizumab bei chronischer RhinoSinusitis mit Polyposis nasi (CRSwNP) im deutschen Gesundheitssystem \u2013 Empfehlungen des \u00c4rzteverbandes Deutscher Allergologen (AeDA) und der AG\u2019s Klinische Immunologie, Allergologie und Umweltmedizin und Rhinologie und Rhinochirurgie der Deutschen Gesellschaft f\u00fcr HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC). Laryngorhinootologie 101(4):284\u2013294","journal-title":"Laryngorhinootologie"},{"issue":"1","key":"1431_CR37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s40629-018-0087-6","volume":"28","author":"G B\u00f6lke","year":"2019","unstructured":"B\u00f6lke\u00a0G, Church\u00a0MK, Bergmann\u00a0K\u2011C (2019) Comparison of extended intervals and dose reduction of omalizumab for asthma control. Allergo J Int 28(1):1\u20134","journal-title":"Allergo J Int"},{"key":"1431_CR38","doi-asserted-by":"crossref","unstructured":"Ciprandi G, Schiavetti I, Ricciardolo FLM (2023) Patients with asthma consulting an allergist differ from those consulting a\u00a0pulmonologist. Allergo J Int","DOI":"10.1007\/s40629-023-00244-x"},{"key":"1431_CR39","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1007\/s40629-016-0093-5","volume":"25","author":"M Lommatzsch","year":"2016","unstructured":"Lommatzsch\u00a0M, Stoll\u00a0P (2016) Novel strategies for the treatment of asthma. Allergo J Int 25:11\u201317","journal-title":"Allergo J Int"},{"issue":"2","key":"1431_CR40","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s40629-018-0079-6","volume":"28","author":"KY Ong","year":"2019","unstructured":"Ong\u00a0KY (2019) What\u2019s new in the global initiative for asthma 2018 report and beyond. Allergo J Int 28(2):63\u201372","journal-title":"Allergo J Int"},{"issue":"7","key":"1431_CR41","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/s40629-018-0051-5","volume":"27","author":"T Rothe","year":"2018","unstructured":"Rothe\u00a0T (2018) A\u00a0century of \u201cintrinsic asthma\u201d. Allergo J Int 27(7):215\u2013219","journal-title":"Allergo J Int"},{"issue":"7","key":"1431_CR42","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1007\/s40629-014-0028-y","volume":"23","author":"C Taube","year":"2014","unstructured":"Taube\u00a0C (2014) Bronchial asthma: is personalized therapy on the horizon? Allergo J Int 23(7):246\u2013251","journal-title":"Allergo J Int"},{"issue":"6","key":"1431_CR43","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1007\/s40629-022-00220-x","volume":"31","author":"L Klimek","year":"2022","unstructured":"Klimek\u00a0L et\u00a0al (2022) Indicating biologics for chronic rhinosinusitis with nasal polyps (CRSwNP). Allergo J Int 31(6):149\u2013160","journal-title":"Allergo J Int"},{"issue":"2","key":"1431_CR44","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1007\/s40629-017-0048-5","volume":"27","author":"M Koennecke","year":"2018","unstructured":"Koennecke\u00a0M et\u00a0al (2018) Subtyping of polyposis nasi: phenotypes, endotypes and comorbidities. Allergo J Int 27(2):56\u201365","journal-title":"Allergo J Int"},{"issue":"4","key":"1431_CR45","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1016\/j.jaci.2021.08.030","volume":"149","author":"C Bachert","year":"2021","unstructured":"Bachert\u00a0C et\u00a0al (2021) Efficacy and safety of benralizumab in chronic rhinosinusitis with nasal polyps: a\u00a0randomized, placebo-controlled trial. J\u00a0Allergy Clin Immunol 149(4):1309\u20131317.e1","journal-title":"J Allergy Clin Immunol"},{"issue":"40","key":"1431_CR46","doi-asserted-by":"publisher","first-page":"e27471","DOI":"10.1097\/MD.0000000000027471","volume":"100","author":"M Bertlich","year":"2021","unstructured":"Bertlich\u00a0M et\u00a0al (2021) Management of chronic rhinosinusitis with nasal polyps in samter triad by low-dose ASA desensitization or dupilumab. Medicine 100(40):e27471","journal-title":"Medicine"},{"issue":"3","key":"1431_CR47","first-page":"226","volume":"58","author":"U Forster-Ruhrmann","year":"2020","unstructured":"Forster-Ruhrmann\u00a0U et\u00a0al (2020) Omalizumab in patients with NSAIDs-exacerbated respiratory disease. Rhinology 58(3):226\u2013232","journal-title":"Rhinology"},{"issue":"7","key":"1431_CR48","doi-asserted-by":"publisher","first-page":"2172","DOI":"10.1016\/j.jaip.2023.04.033","volume":"11","author":"J S\u00e1nchez","year":"2023","unstructured":"S\u00e1nchez\u00a0J et\u00a0al (2023) Nonsteroidal Anti-inflammatory Drug (NSAID) tolerance after biological therapy in patients with NSAID-exacerbated respiratory disease: a\u00a0randomized comparative trial. J\u00a0Allergy Clin Immunol Pract 11(7):2172\u20132179","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"6","key":"1431_CR49","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.1016\/j.jaip.2021.12.030","volume":"10","author":"TM Laidlaw","year":"2022","unstructured":"Laidlaw\u00a0TM et\u00a0al (2022) Controversies in allergy: aspirin desensitization or biologics for aspirin-exacerbated respiratory disease-how to choose. J\u00a0Allergy Clin Immunol Pract 10(6):1462\u20131467","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"5","key":"1431_CR50","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/j.anai.2022.01.043","volume":"128","author":"J Mullur","year":"2022","unstructured":"Mullur\u00a0J et\u00a0al (2022) Aspirin desensitization and biologics in aspirin-exacerbated respiratory disease: efficacy, tolerability, and patient experience. Ann Allergy Asthma Immunol : Off Publ Am Coll Allergy Asthma Immunol 128(5):575\u2013582","journal-title":"Ann Allergy Asthma Immunol : Off Publ Am Coll Allergy Asthma Immunol"},{"issue":"2","key":"1431_CR51","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1002\/alr.22643","volume":"11","author":"AM Sweis","year":"2020","unstructured":"Sweis\u00a0AM et\u00a0al (2020) Major complications of aspirin desensitization and maintenance therapy in aspirin-exacerbated respiratory disease. Int Forum Allergy Rhinol 11(2):115\u2013119","journal-title":"Int Forum Allergy Rhinol"},{"issue":"2","key":"1431_CR52","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.anai.2020.08.008","volume":"126","author":"TM Laidlaw","year":"2020","unstructured":"Laidlaw\u00a0TM (2020) Aspirin desensitization vs biologics for patients with aspirin-exacerbated respiratory disease. Ann Allergy Asthma Immunol : Off Publ Am Coll Allergy Asthma Immunol 126(2):118\u2013119","journal-title":"Ann Allergy Asthma Immunol : Off Publ Am Coll Allergy Asthma Immunol"},{"issue":"1","key":"1431_CR53","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.jaci.2020.11.013","volume":"147","author":"C Bachert","year":"2020","unstructured":"Bachert\u00a0C et\u00a0al (2020) EUFOREA expert board meeting on uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) and biologics: definitions and management. J\u00a0Allergy Clin Immunol 147(1):29\u201336","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"1431_CR54","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1016\/0091-6749(83)90440-2","volume":"71","author":"WR Lumry","year":"1983","unstructured":"Lumry\u00a0WR et\u00a0al (1983) Aspirin-sensitive rhinosinusitis: the clinical syndrome and effects of aspirin administration. J\u00a0Allergy Clin Immunol 71(6):580\u2013587","journal-title":"J Allergy Clin Immunol"},{"issue":"4","key":"1431_CR55","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1016\/j.jaci.2021.09.009","volume":"149","author":"P Oykhman","year":"2021","unstructured":"Oykhman\u00a0P et\u00a0al (2021) Comparative efficacy and safety of monoclonal antibodies and aspirin desensitization for chronic rhinosinusitis with nasal polyposis: a\u00a0systematic review and network meta-analysis. J\u00a0Allergy Clin Immunol 149(4):1286\u20131295","journal-title":"J Allergy Clin Immunol"},{"issue":"5","key":"1431_CR56","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1016\/j.jaip.2015.03.001","volume":"3","author":"V Ta","year":"2015","unstructured":"Ta\u00a0V, White\u00a0AA (2015) Survey-defined patient experiences with aspirin-exacerbated respiratory disease. J\u00a0Allergy Clin Immunol Pract 3(5):711\u2013718","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"1","key":"1431_CR57","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/1939-4551-7-18","volume":"7","author":"R Howe","year":"2014","unstructured":"Howe\u00a0R et\u00a0al (2014) Audit of nasal lysine aspirin therapy in recalcitrant aspirin exacerbated respiratory disease. World Allergy Organ\u00a0J 7(1):18","journal-title":"World Allergy Organ J"},{"issue":"6","key":"1431_CR58","doi-asserted-by":"publisher","first-page":"379","DOI":"10.7326\/0003-4819-150-6-200903170-00006","volume":"150","author":"SR Steinhubl","year":"2009","unstructured":"Steinhubl\u00a0SR et\u00a0al (2009) Aspirin to prevent cardiovascular disease: the association of aspirin dose and clopidogrel with thrombosis and bleeding. Ann Intern Med 150(6):379\u2013386","journal-title":"Ann Intern Med"},{"issue":"4","key":"1431_CR59","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1002\/alr.22709","volume":"11","author":"JV Bosso","year":"2020","unstructured":"Bosso\u00a0JV (2020) Aspirin desensitization for aspirin-exacerbated respiratory disease in the era of biologics: clinical perspective. Int Forum Allergy Rhinol 11(4):822\u2013823","journal-title":"Int Forum Allergy Rhinol"},{"issue":"1","key":"1431_CR60","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.jaci.2007.06.047","volume":"121","author":"M Shaker","year":"2008","unstructured":"Shaker\u00a0M et\u00a0al (2008) An economic analysis of aspirin desensitization in aspirin-exacerbated respiratory disease. J\u00a0Allergy Clin Immunol 121(1):81\u201387","journal-title":"J Allergy Clin Immunol"},{"issue":"4","key":"1431_CR61","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/j.anai.2019.01.018","volume":"122","author":"WC Anderson","year":"2019","unstructured":"Anderson\u00a0WC, Szefler\u00a0SJ (2019) Cost-effectiveness and comparative effectiveness of biologic therapy for asthma: to biologic or not to biologic? Ann Allergy Asthma Immunol : Off Publ Am Coll Allergy Asthma Immunol 122(4):367\u2013372","journal-title":"Ann Allergy Asthma Immunol : Off Publ Am Coll Allergy Asthma Immunol"},{"issue":"2","key":"1431_CR62","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.jaci.2021.06.019","volume":"148","author":"KM Buchheit","year":"2021","unstructured":"Buchheit\u00a0KM, Laidlaw\u00a0TM, Levy\u00a0JM (2021) Immunology-based recommendations for available and upcoming biologics in aspirin-exacerbated respiratory disease. J\u00a0Allergy Clin Immunol 148(2):348\u2013350","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"1431_CR63","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.anai.2018.05.007","volume":"121","author":"DM Lang","year":"2018","unstructured":"Lang\u00a0DM et\u00a0al (2018) Omalizumab can inhibit respiratory reaction during aspirin desensitization. Ann Allergy Asthma Immunol : Off Publ Am Coll Allergy Asthma Immunol 121(1):98\u2013104","journal-title":"Ann Allergy Asthma Immunol : Off Publ Am Coll Allergy Asthma Immunol"},{"issue":"3","key":"1431_CR64","doi-asserted-by":"publisher","first-page":"1384","DOI":"10.1016\/j.jaip.2020.09.007","volume":"9","author":"H Martin","year":"2020","unstructured":"Martin\u00a0H, Barrett\u00a0NA, Laidlaw\u00a0T (2020) Mepolizumab does not prevent all aspirin-induced reactions in patients with aspirin-exacerbated respiratory disease: a\u00a0case series. J\u00a0Allergy Clin Immunol Pract 9(3):1384\u20131385","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"2","key":"1431_CR65","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1016\/j.jaip.2021.09.050","volume":"10","author":"T Quint","year":"2021","unstructured":"Quint\u00a0T et\u00a0al (2021) Omalizumab-induced aspirin tolerance in nonsteroidal anti-inflammatory drug-exacerbated respiratory disease patients is independent of atopic sensitization. J\u00a0Allergy Clin Immunol Pract 10(2):506\u2013516.e6","journal-title":"J Allergy Clin Immunol Pract"},{"key":"1431_CR66","doi-asserted-by":"crossref","unstructured":"Schneider S et\u00a0al (2023) Dupilumab increases aspirin tolerance in NSAID-exacerbated respiratory disease. Eur Respir\u00a0J 61(3)","DOI":"10.1183\/13993003.01335-2022"},{"issue":"3","key":"1431_CR67","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/j.jaci.2021.10.029","volume":"149","author":"GK Scadding","year":"2021","unstructured":"Scadding\u00a0GK, Scadding\u00a0GW (2021) Biologics for chronic rhinosinusitis with nasal polyps (CRSwNP). J\u00a0Allergy Clin Immunol 149(3):895\u2013897","journal-title":"J Allergy Clin Immunol"},{"issue":"12","key":"1431_CR68","doi-asserted-by":"publisher","first-page":"1626","DOI":"10.1002\/alr.22865","volume":"11","author":"M Yong","year":"2021","unstructured":"Yong\u00a0M et\u00a0al (2021) Cost-effectiveness analysis comparing dupilumab and aspirin desensitization therapy for chronic rhinosinusitis with nasal polyposis in aspirin-exacerbated respiratory disease. Int Forum Allergy Rhinol 11(12):1626\u20131636","journal-title":"Int Forum Allergy Rhinol"},{"issue":"2","key":"1431_CR69","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/j.jaip.2021.09.030","volume":"10","author":"H Wangberg","year":"2021","unstructured":"Wangberg\u00a0H et\u00a0al (2021) Appraisal of the real-world effectiveness of biologic therapies in aspirin-exacerbated respiratory disease. J\u00a0Allergy Clin Immunol Pract 10(2):478\u2013484.e3","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"7","key":"1431_CR70","doi-asserted-by":"publisher","first-page":"2910","DOI":"10.1016\/j.jaip.2021.02.020","volume":"9","author":"N Bavaro","year":"2021","unstructured":"Bavaro\u00a0N et\u00a0al (2021) Efficacy of dupilumab in patients with aspirin-exacerbated respiratory disease and previous inadequate response to anti-IL\u20115 or anti-IL-5R\u03b1 in a\u00a0real-world setting. J\u00a0Allergy Clin Immunol Pract 9(7):2910\u20132912.e1","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"4","key":"1431_CR71","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1016\/j.jaci.2020.11.001","volume":"147","author":"WC Scott","year":"2020","unstructured":"Scott\u00a0WC et\u00a0al (2020) Inflammatory heterogeneity in aspirin-exacerbated respiratory disease. J\u00a0Allergy Clin Immunol 147(4):1318\u20131328.e5","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"1431_CR72","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.anai.2022.04.004","volume":"129","author":"L Borish","year":"2022","unstructured":"Borish\u00a0L et\u00a0al (2022) Evaluating enrollment and outcome criteria in trials of biologics for chronic rhinosinusitis with nasal polyps. Ann Allergy Asthma Immunol : Off Publ Am Coll Allergy Asthma Immunol 129(2):160\u2013168","journal-title":"Ann Allergy Asthma Immunol : Off Publ Am Coll Allergy Asthma Immunol"}],"container-title":["HNO"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00106-024-01431-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00106-024-01431-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00106-024-01431-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T12:02:18Z","timestamp":1718971338000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00106-024-01431-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,26]]},"references-count":72,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["1431"],"URL":"https:\/\/doi.org\/10.1007\/s00106-024-01431-0","relation":{},"ISSN":["0017-6192","1433-0458"],"issn-type":[{"value":"0017-6192","type":"print"},{"value":"1433-0458","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,26]]},"assertion":[{"value":"15 January 2024","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 February 2024","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"U.\u00a0F\u00f6rster-Ruhrmann erhielt Honorare f\u00fcr Vortr\u00e4ge von Novartis, AstraZeneca, Sanofi und GSK au\u00dferhalb der vorliegenden Arbeit. J.\u00a0Hagemann erhielt Zuwendungen der Firmen Novartis Pharma GmbH, Sanofi, GlaxoSmithKline (GSK), HAL Allergy f\u00fcr Vortr\u00e4ge au\u00dferhalb der hier vorliegenden Arbeit. M.\u00a0Cuevas erhielt Honorare von AstraZeneca, GSK, Sanofi und Novartis, au\u00dferhalb der eingereichten Arbeit. M.\u00a0Gr\u00f6ger berichtet \u00fcber Zusch\u00fcsse und Vortragshonorare von Sanofi, Novartis, AstraZeneca und GSK, au\u00dferhalb der eingereichten Arbeit. L.\u00a0Klimek erhielt Forschungsstipendien von Allergy Therapeutics\/Bencard, ALK-Abell\u00f3, Allergopharma, ASIT Biotech, AstraZeneca, Bionorica, Biomay, Boehringer Ingelheim, Circassia, Stallergenes, Cytos, Curalogic, HAL, Hartington Pharmaceutical, Lofarma, MEDA\/Mylan, Novartis, LETI Pharma, ROXALL, GlaxoSmithKline (GSK), Sanofi und\/oder war beratend f\u00fcr die oben genannten pharmazeutischen Unternehmen t\u00e4tig. LK ist Herausgeber des Allergo Journal und des Allergo Journal International und er ist der derzeitige Pr\u00e4sident des AeDA (\u00c4rzteverbandes Deutscher Allergologen) und Vizepr\u00e4sident der EAACI. F.\u00a0Klimek hat keine Interessenkonflikte im Zusammenhang mit der vorliegenden Arbeit.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}