{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T10:38:58Z","timestamp":1761302338876,"version":"build-2065373602"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"},{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"}],"funder":[{"name":"Klinikum der Universit\u00e4t M\u00fcnchen"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["HNO"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Hintergrund<\/jats:title>\n                    <jats:p>Die diffus-sklerosierende Osteomyelitis (DSO) ist eine seltene chronische Erkrankung, die mit starken Kieferschmerzen, Schwellung des Unterkiefers und Trismus einhergeht. Eine Beteiligung des Kiefergelenks ist selten, \u00fcber F\u00e4lle mit schwerer Kiefergelenkzerst\u00f6rung bei DSO-Patienten wurde bislang nur selten berichtet.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Fallbericht<\/jats:title>\n                    <jats:p>Der folgende Fallbericht beschreibt den Krankheitsverlauf einer 26-j\u00e4hrigen Patientin mit Zustand nach akuter linksseitiger Otitis media, chronischer Mastoiditis und Osteomyelitis der Sch\u00e4delbasis, die im Verlauf eine DSO im linken Unterkiefer mit schweren degenerativen Ver\u00e4nderungen des Kiefergelenks entwickelte. Die Verabreichung von 6\u202fmg Ibandrons\u00e4ure in Kombination mit einer Arthrozentese und einer arthroskopischen Instillation von Hyalurons\u00e4ure in den Kiefergelenkraum f\u00fchrte zu einer Remission der Symptome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Schlussfolgerung<\/jats:title>\n                    <jats:p>Eine Mastoiditis mit Sch\u00e4delbasisosteomyelitis, mutma\u00dflich verursacht durch eine akute Otitis media, kann zu degenerativen Ver\u00e4nderungen im Kiefergelenk f\u00fchren, insbesondere bei prolongiertem Verlauf oder fortschreitender entz\u00fcndlicher Ausbreitung. Die Kombination mit der Entwicklung einer DSO des Unterkiefers stellt eine m\u00f6gliche Komplikation dar. Das Bewusstsein f\u00fcr das Zusammentreffen der genannten Erkrankungen mit ausstrahlenden pr\u00e4aurikul\u00e4ren Schmerzen ist von entscheidender Bedeutung f\u00fcr die korrekte Diagnose und f\u00fcr ausreichende Behandlungsprotokolle.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00106-025-01649-6","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T04:36:38Z","timestamp":1754973398000},"page":"793-798","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Schwere degenerative Ver\u00e4nderungen des Kiefergelenks in Verbindung mit diffus-sklerosierender Osteomyelitis","Severe degenerative changes of the temporomandibular joint associated with diffuse sclerosing osteomyelitis"],"prefix":"10.1007","volume":"73","author":[{"given":"Ina","family":"Dewenter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Otto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Hildebrandt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenko","family":"Smolka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph A.","family":"Reichel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina Theresa","family":"Obermeier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"issue":"4","key":"1649_CR1","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.bjoms.2020.01.012","volume":"58","author":"MM van de Meent","year":"2020","unstructured":"van de Meent\u00a0MM, Pichardo\u00a0SEC, Appelman-Dijkstra\u00a0NM, van Merkesteyn\u00a0JPR (2020) Outcome of different treatments for chronic diffuse sclerosing osteomyelitis of the mandible: a\u00a0systematic review of published papers. Br J Oral Maxillofac Surg 58(4):385\u2013395","journal-title":"Br J Oral Maxillofac Surg"},{"issue":"12","key":"1649_CR2","doi-asserted-by":"publisher","first-page":"1984","DOI":"10.1016\/j.jcms.2016.09.015","volume":"44","author":"R Luscan","year":"2016","unstructured":"Luscan\u00a0R, Belhous\u00a0K, Simon\u00a0F, Boddaert\u00a0N, Couloigner\u00a0V, Picard\u00a0A et\u00a0al (2016) TMJ arthritis is a\u00a0frequent complication of otomastoiditis. J\u00a0Craniomaxillofac Surg 44(12):1984\u20131987","journal-title":"J Craniomaxillofac Surg"},{"issue":"1","key":"1649_CR3","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.jcms.2003.07.008","volume":"32","author":"M Baltensperger","year":"2004","unstructured":"Baltensperger\u00a0M, Gratz\u00a0K, Bruder\u00a0E, Lebeda\u00a0R, Makek\u00a0M, Eyrich\u00a0G (2004) Is primary chronic osteomyelitis a\u00a0uniform disease? Proposal of a\u00a0classification based on a\u00a0retrospective analysis of patients treated in the past 30\u00a0years. J\u00a0Craniomaxillofac Surg 32(1):43\u201350","journal-title":"J Craniomaxillofac Surg"},{"issue":"10","key":"1649_CR4","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1111\/j.1600-0714.2006.00454.x","volume":"35","author":"M Montonen","year":"2006","unstructured":"Montonen\u00a0M, Li\u00a0TF, Lukinmaa\u00a0PL, Sakai\u00a0E, Hukkanen\u00a0M, Sukura\u00a0A et\u00a0al (2006) RANKL and cathepsin K in diffuse sclerosing osteomyelitis of the mandible. J\u00a0Oral Pathol Med 35(10):620\u2013625","journal-title":"J Oral Pathol Med"},{"issue":"8","key":"1649_CR5","doi-asserted-by":"publisher","first-page":"1990","DOI":"10.1016\/j.jcms.2014.09.004","volume":"42","author":"A Mari","year":"2014","unstructured":"Mari\u00a0A, Morla\u00a0A, Melero\u00a0M, Schiavone\u00a0R, Rodriguez\u00a0J (2014) Diffuse sclerosing osteomyelitis (DSO) of the mandible in SAPHO syndrome: a\u00a0novel approach with anti-TNF therapy. Systematic review. J\u00a0Craniomaxillofac Surg 42(8):1990\u20131996","journal-title":"J Craniomaxillofac Surg"},{"issue":"5","key":"1649_CR6","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1016\/0030-4220(94)90170-8","volume":"78","author":"MF Kahn","year":"1994","unstructured":"Kahn\u00a0MF, Hayem\u00a0F, Hayem\u00a0G, Grossin\u00a0M (1994) Is diffuse sclerosing osteomyelitis of the mandible part of the synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome? Analysis of seven cases. Oral Surg Oral Med Oral Pathol 78(5):594\u2013598","journal-title":"Oral Surg Oral Med Oral Pathol"},{"issue":"12","key":"1649_CR7","doi-asserted-by":"publisher","first-page":"1922","DOI":"10.1016\/j.jcms.2019.11.020","volume":"47","author":"MM van de Meent","year":"2019","unstructured":"van de Meent\u00a0MM, Wetselaar-Glas\u00a0MJM, Fiocco\u00a0M, Appelman-Dijkstra\u00a0NM, van Merkesteyn\u00a0JPR (2019) Non-surgical treatment of adults with chronic diffuse sclerosing osteomyelitis\/tendoperiostitis of the mandible. J\u00a0Craniomaxillofac Surg 47(12):1922\u20131928","journal-title":"J Craniomaxillofac Surg"},{"issue":"9","key":"1649_CR8","doi-asserted-by":"publisher","first-page":"1837","DOI":"10.1016\/j.jcms.2015.08.028","volume":"43","author":"S Otto","year":"2015","unstructured":"Otto\u00a0S, Troeltzsch\u00a0M, Burian\u00a0E, Mahaini\u00a0S, Probst\u00a0F, Pautke\u00a0C et\u00a0al (2015) Ibandronate treatment of diffuse sclerosing osteomyelitis of the mandible: Pain relief and insight into pathogenesis. J\u00a0Craniomaxillofac Surg 43(9):1837\u20131842","journal-title":"J Craniomaxillofac Surg"},{"issue":"1","key":"1649_CR9","doi-asserted-by":"publisher","first-page":"6","DOI":"10.11607\/jop.1151","volume":"28","author":"E Schiffman","year":"2014","unstructured":"Schiffman\u00a0E, Ohrbach\u00a0R, Truelove\u00a0E, Look\u00a0J, Anderson\u00a0G, Goulet\u00a0JP et\u00a0al (2014) Diagnostic Criteria for Temporomandibular Disorders (DC\/TMD) for Clinical and Research Applications: recommendations of the International RDC\/TMD Consortium Network* and Orofacial Pain Special Interest Groupdagger. J\u00a0Oral Facial Pain Headache 28(1):6\u201327","journal-title":"J Oral Facial Pain Headache"},{"issue":"5","key":"1649_CR10","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1177\/0022034515574770","volume":"94","author":"XD Wang","year":"2015","unstructured":"Wang\u00a0XD, Zhang\u00a0JN, Gan\u00a0YH, Zhou\u00a0YH (2015) Current understanding of pathogenesis and treatment of TMJ osteoarthritis. J\u00a0Dent Res 94(5):666\u2013673","journal-title":"J Dent Res"},{"key":"1649_CR11","doi-asserted-by":"crossref","unstructured":"Derwich M, Mitus-Kenig M, Pawlowska E (2021) Mechanisms of Action and Efficacy of Hyaluronic Acid, Corticosteroids and Platelet-Rich Plasma in the Treatment of Temporomandibular Joint Osteoarthritis\u2014A Systematic Review. Int J Mol Sci 22(14)","DOI":"10.3390\/ijms22147405"}],"container-title":["HNO"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00106-025-01649-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00106-025-01649-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00106-025-01649-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T10:34:46Z","timestamp":1761302086000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00106-025-01649-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,12]]},"references-count":11,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["1649"],"URL":"https:\/\/doi.org\/10.1007\/s00106-025-01649-6","relation":{},"ISSN":["0017-6192","1433-0458"],"issn-type":[{"type":"print","value":"0017-6192"},{"type":"electronic","value":"1433-0458"}],"subject":[],"published":{"date-parts":[[2025,8,12]]},"assertion":[{"value":"29 April 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 August 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"I.\u00a0Dewenter, S.\u00a0Otto, T.\u00a0Hildebrandt, W.\u00a0Smolka, C.A.\u00a0Reichel und K.T.\u00a0Obermeier geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patient\/-innen zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern\/Vertreterinnen eine schriftliche Einwilligung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}