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Ergibt die Diagnostik den Verdacht oder Nachweis eines Schilddr\u00fcsenkarzinoms, bleibt die chirurgische Therapie nach wie vor in den meisten F\u00e4llen die vordergr\u00fcndige Behandlungsoption.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Fragestellung<\/jats:title>\n                    <jats:p>Ziel dieser Arbeit ist es, einen \u00dcberblick \u00fcber das leitliniengerechte Vorgehen bei Schilddr\u00fcsenknoten und -karzinomen mit Fokus auf Diagnostik und chirurgische Therapie zu geben. Hierbei werden wesentliche inhaltliche Unterschiede zwischen der bisherigen und der aktuellen Leitlinie herausgearbeitet.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material und Methoden<\/jats:title>\n                    <jats:p>Selektion der praxisrelevantesten Empfehlungen der 2025 erschienenen Leitlinie \u201eSchilddr\u00fcsenkarzinom\u201c und Vergleich dieser mit den Empfehlungen der 2012 erschienenen Leitlinie \u201eOperative Therapie maligner Schilddr\u00fcsenerkrankungen\u201c.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ergebnisse<\/jats:title>\n                    <jats:p>Die neue Leitlinie ist deutlich umfangreicher und detaillierter. Das empfohlene diagnostische Vorgehen wird pr\u00e4zisiert und durch Untersuchungstechniken wie die Elastographie erg\u00e4nzt. Das operative Vorgehen beh\u00e4lt seine Rolle als prim\u00e4re therapeutische S\u00e4ule. Entsprechend der aktuellen Studienlage werden hier neue Optionen, wie das beobachtende Verhalten papill\u00e4rer Mikrokarzinome unter definierten Voraussetzungen, aufgenommen. Die Empfehlungen zu Diagnostik und Therapie undifferenzierter Schilddr\u00fcsenkarzinome wurden ma\u00dfgeblich erweitert.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Schlussfolgerung<\/jats:title>\n                    <jats:p>Die neue Leitlinie gibt einen umfassenden \u00dcberblick \u00fcber Diagnostik und Therapie bei Schilddr\u00fcsenkarzinomen und erweitert die bisherige Leitlinie unter Ber\u00fccksichtigung der aktuellen Studienlage.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00106-025-01654-9","type":"journal-article","created":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T09:52:59Z","timestamp":1756720379000},"page":"753-760","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["S3-Leitlinie Schilddr\u00fcsenkarzinom: Was ist neu?","S3\u00a0guidelines on thyroid cancer: what is new?"],"prefix":"10.1007","volume":"73","author":[{"given":"Lukas","family":"Kuczera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarina Katrin","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matti","family":"Sievert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,9,1]]},"reference":[{"issue":"6","key":"1654_CR1","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1016\/j.beem.2008.09.019","volume":"22","author":"DS Dean","year":"2008","unstructured":"Dean\u00a0DS, Gharib\u00a0H (2008) Epidemiology of thyroid nodules. 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