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In Ermangelung anerkannter MCID-Grenzwerte im Bereich der Cochleaimplantat(CI)-Versorgung in Deutschland wurde ein Methodenger\u00fcst f\u00fcr zuk\u00fcnftige klinische Studien entwickelt, welches auf einer zweifach gestuften ankerbasierten retrospektiven Abfrage (1.\u00a0bedeutsame Ver\u00e4nderung und 2.\u00a0Ausma\u00df der bedeutsamen Ver\u00e4nderung, 6\u2011Punkte-Likert-Skala) gem\u00e4\u00df den drei PROM-Dimensionen basiert. Hierbei sollen MCID-Grenzwerte f\u00fcr drei unterschiedliche Gruppen des Schweregrads bei CI-Patienten, einseitige Taubheit (SSD), asymmetrischer (AHL) und symmetrischer H\u00f6rverlust (SHL) ermittelt werden. Es wird vorgeschlagen, mit Pilotdaten zun\u00e4chst eine Fallzahlsch\u00e4tzung vorzunehmen sowie Grenzwerte von Korrelationen\u00a0(r) des PROM mit der Ankerfrage zur Baseline (r\u202f&lt;\u20090,1) und Follow-up (r\u202f&gt;\u20090,2) zu beachten. Die Korrelation des Differenzwerts des PROM im Vorher-nachher-Vergleich zur Ankerfrage sollte hierbei r\u202f&gt;\u20090,5\u00a0sein, um nachfolgend Cut-off-Werte mittels logistischer Regressionen\/Receiver Operating Characteristic (ROC) zu bestimmen. MCID-Grenzwerte k\u00f6nnen zuk\u00fcnftig im Bereich der Umversorgung von CI-Soundprozessoren f\u00fcr die Einzelfallentscheidung erg\u00e4nzend herangezogen werden und geben eine Orientierungshilfe im Bereich einer optimierten CI-Anpassung und Rehabilitation.<\/jats:p>","DOI":"10.1007\/s00106-026-01815-4","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:07:46Z","timestamp":1791371266000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Methodische Implikationen zur minimalen klinisch relevanten Differenz von Frageb\u00f6gen als Patient-Reported Outcome Measures im Bereich der CI-Versorgung","Methodological implications of the minimal clinically important difference in patient-reported outcome measures in the field of cochlear implant provision. 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KG erhalten. Ulrich Hoppe erhielt Unterst\u00fctzung durch einen Forschungszuschuss von Cochlear Ltd., London. Susen Lailach hat Forschungsmittel von der MED-EL Germany GmbH und der Cochlear Deutschland GmbH &amp; Co. KG erhalten. Heidi Olze hat Forschungsmittel von der MED-EL Germany GmbH und der Cochlear Deutschland GmbH &amp; Co. KG erhalten. Bis zum 30. September 2025 war Markus Meis bei der Cochlear Deutschland GmbH &amp; Co. KG besch\u00e4ftigt. Ab dem 01.10.2025 war er bei der H\u00f6rzentrum Oldenburg gGmbH t\u00e4tig.","order":1,"name":"Ethics","label":"Interessenkonflikt","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}}]}}