{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T04:28:00Z","timestamp":1648960080101},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Internist"],"published-print":{"date-parts":[[2005,6]]},"DOI":"10.1007\/s00108-005-1380-2","type":"journal-article","created":{"date-parts":[[2005,3,30]],"date-time":"2005-03-30T13:10:14Z","timestamp":1112188214000},"page":"690-694","source":"Crossref","is-referenced-by-count":2,"title":["Alopecia totalis, Hypotonie und erektile Dysfunktion bei einem 34-j\u00e4hrigen Mann"],"prefix":"10.1007","volume":"46","author":[{"given":"W.","family":"Hunger-Dathe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Braun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U. A.","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"1380_CR1","doi-asserted-by":"crossref","unstructured":"Neufeld M, Maclaren NK, Blizzard RM (1981) Two types of autoimmune Addison\u2019s disease associated with different polyglandular autoimmune (PGA) syndromes. Medicine (Baltimore) 60: 355\u2013362","DOI":"10.1097\/00005792-198109000-00003"},{"key":"1380_CR2","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1056\/NEJM199006283222601","volume":"322","author":"Ahonen","year":"1990","unstructured":"Ahonen P, Myllarniemi S, Sipila I, Perheentupa J (1990) Clinical variation of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in a series of 68 patients. N Engl J Med 322: 1829\u20131836","journal-title":"N Engl J Med"},{"key":"1380_CR3","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/00000441-198508000-00007","volume":"290","author":"Leshin","year":"1985","unstructured":"Leshin M (1985) Polyglandular autoimmune syndromes. Am J Med Sci 290: 77\u201388","journal-title":"Am J Med Sci"},{"key":"1380_CR4","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1111\/j.1365-2265.1994.tb03023.x","volume":"40","author":"Pholsena","year":"1994","unstructured":"Pholsena M, Young J, Couzinet B, Schaison G (1994) Primary adrenal and thyroid insufficiencies associated with hypopituitarism: a diagnostic challenge. Clin Endocrinol (Oxf) 40: 693\u2013695","journal-title":"Clin Endocrinol (Oxf)"},{"key":"1380_CR5","first-page":"327","volume":"77","author":"Bunnag","year":"1994","unstructured":"Bunnag P, Rajatanavin R (1994) Polyglandular autoimmune (PGA) syndromes: report of three cases and review of the literature. J Med Assoc Thai 77: 327\u2013333","journal-title":"J Med Assoc Thai"},{"key":"1380_CR6","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1530\/acta.0.1220472","volume":"122","author":"Papadopoulos","year":"1990","unstructured":"Papadopoulos K, Hallengren B (1990) Polyglandular autoimmune syndrome type II in patients with idiopathic Addison\u2019s disease. Acta Endocrinol (Copenh) 122: 472\u2013478","journal-title":"Acta Endocrinol (Copenh)"},{"key":"1380_CR7","first-page":"19","volume":"6","author":"Kahaly","year":"1997","unstructured":"Kahaly G, F\u00f6rster G, Otto E, Hansen C, Schulz G (1997) Diabetes mellitus Typ I als ein Teil des polyglandul\u00e4ren Autoimmunsyndroms. Diabetes Stoffwechsel 6: 19\u201327","journal-title":"Diabetes Stoffwechsel"},{"key":"1380_CR8","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1111\/j.1365-2796.1994.tb00859.x","volume":"236","author":"Papadopoulos","year":"1994","unstructured":"Papadopoulos KI, Hornblad Y, Hallengren B (1994) The occurrence of polyglandular autoimmune syndrome type III associated with coeliac disease in patients with sarcoidosis. J Intern Med 236: 661\u2013663","journal-title":"J Intern Med"},{"key":"1380_CR9","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1046\/j.1365-2249.2001.01668.x","volume":"126","author":"De Block","year":"2001","unstructured":"De Block CE, De Leeuw IH, Vertommen JJ et al. (2001) Beta-cell, thyroid, gastric, adrenal and coeliac autoimmunity and HLA-DQ types in type 1 diabetes. Clin Exp Immunol 126: 236\u2013241","journal-title":"Clin Exp Immunol"},{"key":"1380_CR10","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1006\/jaut.1995.0009","volume":"8","author":"Zelissen","year":"1995","unstructured":"Zelissen PM, Bast EJ, Croughs RJ (1995) Associated autoimmunity in Addison\u2019s disease. J Autoimmun 8: 121\u2013130","journal-title":"J Autoimmun"},{"key":"1380_CR11","doi-asserted-by":"crossref","first-page":"82","DOI":"10.2337\/diacare.26.1.82","volume":"26","author":"De Block","year":"2003","unstructured":"De Block CE, De Leeuw IH, Bogers JJ et al. (2003) Autoimmune gastropathy in type 1 diabetic patients with parietal cell antibodies: histological and clinical findings. Diabetes Care 26: 82\u201388","journal-title":"Diabetes Care"},{"key":"1380_CR12","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.1210\/jc.2002-021845","volume":"88","author":"Dittmar","year":"2003","unstructured":"Dittmar M, Kahaly GJ (2003) Polyglandular autoimmune syndromes: immunogenetics and long-term follow-up. J Clin Endocrinol Metab 88: 2983\u20132992","journal-title":"J Clin Endocrinol Metab"},{"key":"1380_CR13","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1530\/eje.0.1480245","volume":"148","author":"Hansen","year":"2003","unstructured":"Hansen D, Bennedbaek FN, Hoier-Madsen M, Hegedus L, Jacobsen BB (2003) A prospective study of thyroid function, morphology and autoimmunity in young patients with type 1 diabetes. Eur J Endocrinol 148: 245\u2013251","journal-title":"Eur J Endocrinol"},{"key":"1380_CR14","unstructured":"Pfannenstiel P, Hotze LA, Schaller B (1999) Schilddr\u00fcsenkrankheiten: Diagnose und Therapie. In: Berlin H (Hrsg) Berliner Medizinische Verlagsanstalt GmbH"},{"key":"1380_CR15","first-page":"1971","volume":"124","author":"Weyermann","year":"1994","unstructured":"Weyermann D, Spinas G, Roth S, Guglielmetti M, Viollier E, Staub JJ (1994) Combined endocrine autoimmune syndrome \u2014 incidence, forms of manifestation and clinical significance. Schweiz Med Wochenschr 124: 1971\u20131975","journal-title":"Schweiz Med Wochenschr"},{"key":"1380_CR16","doi-asserted-by":"crossref","first-page":"S52","DOI":"10.1177\/1071557601008001S16","volume":"8","author":"Maclaren","year":"2001","unstructured":"Maclaren N, Chen QY, Kukreja A, Marker J, Zhang CH, Sun ZS (2001) Autoimmune hypogonadism as part of an autoimmune polyglandular syndrome. J Soc Gynecol Investig 8: S52\u201354","journal-title":"J Soc Gynecol Investig"},{"key":"1380_CR17","first-page":"325","volume":"104","author":"Schmitt","year":"1992","unstructured":"Schmitt K, Tulzer G, Tulzer W (1992) Polyglandular type I autoimmune syndrome. Wien Klin Wochenschr 104: 325\u2013327","journal-title":"Wien Klin Wochenschr"},{"key":"1380_CR18","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1056\/NEJM198506133122402","volume":"312","author":"Barkan","year":"1985","unstructured":"Barkan AL, Kelch RP, Marshall JC (1985) Isolated gonadotrope failure in the polyglandular autoimmune syndrome. N Engl J Med 312: 1535\u20131540","journal-title":"N Engl J Med"},{"key":"1380_CR19","first-page":"2909","volume":"86","author":"Ten","year":"2001","unstructured":"Ten S, New M, Maclaren N (2001) Clinical review 130: Addison\u2019s disease 2001. J Clin Endocrinol Metab 86: 2909\u20132922","journal-title":"J Clin Endocrinol Metab"},{"key":"1380_CR20","first-page":"1545","volume":"85","author":"Chen","year":"2000","unstructured":"Chen QY, Nadell D, Zhang XY et al. (2000) The human leukocyte antigen HLA DRB3*020\/DQA1*0501 haplotype is associated with Graves\u2018 disease in African Americans. J Clin Endocrinol Metab 85: 1545\u20131549","journal-title":"J Clin Endocrinol Metab"},{"key":"1380_CR21","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s00109-001-0306-2","volume":"80","author":"Vogel","year":"2002","unstructured":"Vogel A, Strassburg CP, Obermayer-Straub P, Brabant G, Manns MP (2002) The genetic background of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy and its autoimmune disease components. J Mol Med 80: 201\u2013211","journal-title":"J Mol Med"},{"key":"1380_CR22","doi-asserted-by":"crossref","unstructured":"(1997) An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. The Finnish-German APECED Consortium. Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy. Nat Genet 17: 399\u2013403","DOI":"10.1038\/ng1297-399"},{"key":"1380_CR23","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/ng1297-393","volume":"17","author":"Nagamine","year":"1997","unstructured":"Nagamine K, Peterson P, Scott HS et al. (1997) Positional cloning of the APECED gene. Nat Genet 17: 393\u2013398","journal-title":"Nat Genet"},{"key":"1380_CR24","first-page":"51","volume":"22","author":"Iannello","year":"1997","unstructured":"Iannello S, Campanile E, Cipolli D et al. (1997) A rare case of juvenile diabetes mellitus associated with APECED (autoimmune poly-endocrinopathy, candidiasis and ectodermal dystrophy) with strong X-linked familial inheritance. Minerva Endocrinol 22: 51\u201359","journal-title":"Minerva Endocrinol"},{"key":"1380_CR25","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1002\/1521-4141(200007)30:7<1884::AID-IMMU1884>3.0.CO;2-P","volume":"30","author":"Heino","year":"2000","unstructured":"Heino M, Peterson P, Sillanpaa N (2000) RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse. Eur J Immunol 30: 1884\u20131893","journal-title":"Eur J Immunol"},{"key":"1380_CR26","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/humu.20003","volume":"23","author":"Halonen","year":"2004","unstructured":"Halonen M, Kangas H, Ruppell T et al. (2004) APECED-causing mutations in AIRE reveal the functional domains of the protein. Hum Mutat 23: 245\u2013257","journal-title":"Hum Mutat"},{"key":"1380_CR27","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1007\/BF03345516","volume":"25","author":"Meyer","year":"2002","unstructured":"Meyer G, Badenhoop K (2002) Autoimmune regulator (AIRE) gene on chromosome 21: implications for autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) any more common manifestations of endocrine autoimmunity. J Endocrinol Invest 25: 804\u2013811","journal-title":"J Endocrinol Invest"},{"key":"1380_CR28","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3109\/07853899708998786","volume":"31","author":"Aaltonen","year":"1999","unstructured":"Aaltonen J, Bjorses P (1999) Cloning of the APECED gene provides new insight into human autoimmunity. Ann Med 31: 111\u2013116","journal-title":"Ann Med"}],"container-title":["Der Internist"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-005-1380-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00108-005-1380-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-005-1380-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T04:11:31Z","timestamp":1558584691000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00108-005-1380-2"}},"subtitle":["Schwierige Kl\u00e4rung einer gemeinsamen Ursache"],"short-title":[],"issued":{"date-parts":[[2005,6]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["1380"],"URL":"https:\/\/doi.org\/10.1007\/s00108-005-1380-2","relation":{},"ISSN":["0020-9554","1432-1289"],"issn-type":[{"value":"0020-9554","type":"print"},{"value":"1432-1289","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,6]]}}}