{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T12:24:36Z","timestamp":1788006276683,"version":"build-2784847793"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T00:00:00Z","timestamp":1204848000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Internist"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1007\/s00108-008-2039-6","type":"journal-article","created":{"date-parts":[[2008,3,5]],"date-time":"2008-03-05T13:06:03Z","timestamp":1204722363000},"page":"737-742","source":"Crossref","is-referenced-by-count":3,"title":["52-j\u00e4hrige Patientin mit akuter Schocksymptomatik und Purpura fulminans","A 52-year-old woman with acute shock and purpura fulminans"],"prefix":"10.1007","volume":"49","author":[{"given":"E.","family":"Jochum","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Perez-Bouza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Baumanns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"vom Dahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Janssen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,3,7]]},"reference":[{"key":"2039_CR1","first-page":"5","volume":"32","author":"Beytout","year":"2003","unstructured":"Beytout J, Tournilhac O, Laurichesse H (2003) Asplenia and hyposplenism. Presse Med 32: 5\u20139","journal-title":"Presse Med"},{"key":"2039_CR2","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1099\/00222615-28-4-237","volume":"28","author":"Gillespie","year":"1989","unstructured":"Gillespie SH (1989) Aspects of pneumoccocal infection including bacterial virulence, host response and vaccination. J Med Microbiol 28: 237\u2013248","journal-title":"J Med Microbiol"},{"key":"2039_CR3","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/infdis\/142.6.923","volume":"142","author":"Gray","year":"1980","unstructured":"Gray BM, Converse GM, Dillin HC jr. (1980) Epidemiologic studies of Streptoccocus pneumoniae in infants: acquisition, carriage and infection during the first 24\u00a0months of life. J Infect Dis 142: 923\u2013933","journal-title":"J Infect Dis"},{"key":"2039_CR4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s100240010145","volume":"4","author":"Hansen","year":"2001","unstructured":"Hansen K, Singer DB (2001) Asplenic-hyposplenic overwhelming sepsis: postsplenectomy sepsis revisited. Pediatr Dev Pathol 4: 105\u2013121","journal-title":"Pediatr Dev Pathol"},{"key":"2039_CR5","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1093\/clinids\/13.Supplement_6.S509","volume":"13","author":"Johnston","year":"1991","unstructured":"Johnston RB jr.(1991) Pathogenesis of pneumoccocal pneumonia. Rev Infect Dis 13: 509\u2013517","journal-title":"Rev Infect Dis"},{"key":"2039_CR6","first-page":"74","volume":"37","author":"K\u00f6nig","year":"1996","unstructured":"K\u00f6nig G, Guggenberger M, Bommersbach B (1996) 40-j\u00e4hriger Patient ohne Vorerkrankungen mit akuter Schocksymptomatik und schwerer Verbrauchskoagulopathie. Internist 37: 74\u201377","journal-title":"Internist"},{"key":"2039_CR7","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/ajh.2830020210","volume":"2","author":"Krivit","year":"1977","unstructured":"Krivit W (1977) Overwhelming postsplenectomy infection. Am J Hematol 2: 193\u2013201","journal-title":"Am J Hematol"},{"key":"2039_CR8","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1001\/jama.294.16.2043","volume":"294","author":"Lexau","year":"2005","unstructured":"Lexau CA, Lynfield R, Danila R, Pilishvili T et al. (2005) Active bacterial core surveillance team. Changing epidemiology of invasive pneumococcal disease among older adults in the era of pediatric pneumococcal conjugate vaccine. JAMA 294: 2043\u20132051","journal-title":"JAMA"},{"key":"2039_CR9","doi-asserted-by":"crossref","unstructured":"Lode H, Wagner J, M\u00fcller F, Hund M et al. (1989) Epidemiologie, Klinik und Prognose der Sepsis bei 691\u00a0Patienten. In: Reinhart K, Eyrich K (Hrsg) Sepsis. Springer, Berlin Heidelberg New York, S.\u00a08\u201313","DOI":"10.1007\/978-3-662-09869-1_2"},{"key":"2039_CR10","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1007\/s002770100373","volume":"80","author":"Nanan","year":"2001","unstructured":"Nanan R, Peters K, Schrod L, Kreth HW (2001) Lethal pneumococcal infection in an 18-month-old girl with splenic hypoplasia and dysgammaglobulinemia. Ann Hematol 80: 674\u2013676","journal-title":"Ann Hematol"},{"key":"2039_CR11","unstructured":"\u00d6ks\u00fcz M (2004) Systemische Infektionen mit Streptokokkus pneumoniae. Epidemiologische Auswertung und Analyse der humoralen Immunantwort gegen Pneumokokkenproteine. Medizinische Dissertation aus dem Institut f\u00fcr Mikrobiologie, Heinrich Heine Universit\u00e4t D\u00fcsseldorf"},{"key":"2039_CR12","first-page":"191","volume":"14","author":"Overturf","year":"1999","unstructured":"Overturf GD (1999) Infections and immunizations of children with sickle cell disease. Adv Pediatr Infect Dis 14: 191\u2013218","journal-title":"Adv Pediatr Infect Dis"},{"key":"2039_CR13","doi-asserted-by":"crossref","unstructured":"Price VE, Dutta S, Blanchette VS, Butchart S et al. (2006) The prevention and treatment of bacterial infections in children with asplenia or hyposplenia: practice considerations at the Hospital for Sick Children, Toronto, Pediatr Blood Cancer 46: 597\u2013603","DOI":"10.1002\/pbc.20477"},{"key":"2039_CR14","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1080\/00365540500277755","volume":"38","author":"Schumann","year":"2006","unstructured":"Schumann C, Triantafilou K, Kamenz J, Hanke H et al. (2006) Septic shock caused by Streptococcus pneumoniae in a post-splenectomy patient successfully treated with recombinant human activated protein\u00a0C. Scand J Infect Dis 38: 139\u2013142","journal-title":"Scand J Infect Dis"},{"key":"2039_CR15","first-page":"255","volume":"31","author":"St\u00e4ndige","year":"2006","unstructured":"St\u00e4ndige Impfkommission am Robert Koch-Institut (STIKO) (2006) Begr\u00fcndung der STIKO-Empfehlungen zur Impfung gegen Pneumokokken und Meningokokken vom Juli 2006. Epidemiologisches Bulletin 31: 255\u2013260","journal-title":"Epidemiologisches Bulletin"},{"key":"2039_CR16","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1093\/clinids\/3.2.299","volume":"3","author":"Wara","year":"1981","unstructured":"Wara DW (1981) Host defense against Streptococcus pneumoniae: the role of the spleen. Rev Infect 3: 299\u2013309","journal-title":"Rev Infect"},{"key":"2039_CR17","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1093\/clinids\/14.5.1124","volume":"14","author":"Wong","year":"1992","unstructured":"Wong WY, Overturf GD, Powars DE (1992) Infection caused by Streptococcus pneumoniae in children with sickle cell disease: epidemiology, immunologic mechanisms, prophylaxis and vaccination. Clin Infect 14: 1124\u20131136","journal-title":"Clin Infect"}],"container-title":["Der Internist"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-008-2039-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00108-008-2039-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-008-2039-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T04:12:07Z","timestamp":1558584727000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00108-008-2039-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,7]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["2039"],"URL":"https:\/\/doi.org\/10.1007\/s00108-008-2039-6","relation":{},"ISSN":["0020-9554","1432-1289"],"issn-type":[{"value":"0020-9554","type":"print"},{"value":"1432-1289","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,7]]}}}