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So kommt es unter anderem zu einer Abschw\u00e4chung von Muskeleigenreflexen und Propriozeption. Davon abzugrenzen sind Polyneuropathien als krankhafte Ver\u00e4nderungen des peripheren Nervensystems. Die j\u00e4hrliche Inzidenz von Polyneuropathien wird auf 118\/100.000 gesch\u00e4tzt, die Pr\u00e4valenz liegt bei etwa 1\u202f%, f\u00fcr \u00e4ltere Populationen werden 7\u202f% angegeben. Die Ursachen sind vielf\u00e4ltig und \u00e4hnlich den Ursachen von Neuropathien des j\u00fcngeren Alters: Neben metabolischen, immunvermittelten, heredit\u00e4ren, toxischen und infekti\u00f6sen \u00c4tiologien k\u00f6nnen Polyneuropathien Ausdruck von Systemerkrankungen sein. Entsprechend der Altersverteilung der verschiedenen Ursachen sind Neuropathien im Zusammenhang mit Diabetes, monoklonalen Gammopathien und Malignomen im Alter h\u00e4ufiger. Allerdings nimmt der Anteil der kryptogenen Neuropathien, also ohne eindeutige Ursache, mit dem Alter zu. Bei alten Menschen f\u00fchren Polyneuropathien zu einer zus\u00e4tzlichen Beeintr\u00e4chtigung der Mobilit\u00e4t und einem erh\u00f6hten Sturzrisiko, was auch die Abkl\u00e4rung funktioneller F\u00e4higkeiten erforderlich macht.<\/jats:p>","DOI":"10.1007\/s00108-020-00748-6","type":"journal-article","created":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T17:03:01Z","timestamp":1581008581000},"page":"254-260","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Polyneuropathie im Alter","Polyneuropathy in older individuals"],"prefix":"10.1007","volume":"61","author":[{"given":"W. 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