{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:17:58Z","timestamp":1791987478755,"version":"4.4.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T00:00:00Z","timestamp":1666569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T00:00:00Z","timestamp":1666569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Innere Medizin"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1007\/s00108-022-01429-2","type":"journal-article","created":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T10:02:40Z","timestamp":1666605760000},"page":"1298-1306","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Nachweis positiver Versorgungseffekte von digitalen Gesundheitsanwendungen\u00a0\u2013 methodische Herausforderungen und L\u00f6sungsans\u00e4tze","Evidence of positive care effects by digital health apps\u2014methodological challenges and approaches"],"prefix":"10.1007","volume":"63","author":[{"given":"Inke R.","family":"K\u00f6nig","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirja","family":"Mittermaier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Sina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Raspe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Stais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Gamst\u00e4tter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Stachwitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Wolfrum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jutta G.","family":"Richter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"M\u00f6ckel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Arbeitsgruppe Digitale Gesundheitsanwendungen (DiGA) und k\u00fcnstliche Intelligenz (KI) in Leitlinien der Kommission Digitale Transformation der Deutschen Gesellschaft f\u00fcr Innere Medizin (DGIM)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,10,24]]},"reference":[{"key":"1429_CR1","unstructured":"BfArM (2022) DiGA-Verzeichnis. Bundesinstitut f\u00fcr Arzneimittel und Medizinprodukte. https:\/\/diga.bfarm.de\/de\/verzeichnis?type=%5B%5D. Zugegriffen: 03.10.2022"},{"key":"1429_CR2","unstructured":"BfArM (2022) Leitfaden und Ausf\u00fcllhilfe. Bundesamt f\u00fcr Arzneimittel und Medizinprodukte. https:\/\/www.bfarm.de\/DE\/Medizinprodukte\/Portale\/DiGA\/_node.html. Zugegriffen: 03.10.2022"},{"key":"1429_CR3","first-page":"2562","volume":"2019","author":"Bundestag","year":"2019","unstructured":"Bundestag (2019) Digitale-Versorgung-Gesetz \u2013 DVG. Bundesgesetzblatt 2019:2562\u20132584","journal-title":"Bundesgesetzblatt"},{"key":"1429_CR4","first-page":"768","volume":"2020","author":"Bundestag","year":"2020","unstructured":"Bundestag (2020) Digitale Gesundheitsanwendungen-Verordnung \u2013 DIGAV. Bundesgesetzblatt 2020:768\u2013798","journal-title":"Bundesgesetzblatt"},{"key":"1429_CR5","doi-asserted-by":"publisher","first-page":"2337","DOI":"10.1001\/jama.2017.18556","volume":"318","author":"C Gamble","year":"2017","unstructured":"Gamble\u00a0C, Krishan\u00a0A, Stocken\u00a0D et\u00a0al (2017) Guidelines for the content of statistical analysis plans in clinical trials. J\u00a0Am Med Assoc 318:2337\u20132343","journal-title":"J Am Med Assoc"},{"key":"1429_CR6","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1007\/s00103-021-03422-w","volume":"64","author":"P Heimann","year":"2021","unstructured":"Heimann\u00a0P, Lorenz\u00a0N, Blum\u00a0N et al (2021) Experiences of digital health care applications (DIGA) manufacturers with the BfArM Fast-Track procedure. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 64:1249\u20131253","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"key":"1429_CR7","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.invent.2014.12.003","volume":"2","author":"B Meyer","year":"2015","unstructured":"Meyer\u00a0B, Bierbrodt\u00a0J, Schr\u00f6der\u00a0J et\u00a0al (2015) Effects of an internet intervention (deprexis) on severe depression symptoms: randomized controlled trial. Internet Interv 2:48\u201359","journal-title":"Internet Interv"},{"key":"1429_CR8","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1007\/s00108-022-01264-5","volume":"63","author":"M Mittermaier","year":"2022","unstructured":"Mittermaier\u00a0M, Sina\u00a0C, Richter\u00a0JG et\u00a0al (2022) Practical use of digital health applications (DiGA) in internal medicine. Internist 63:245\u2013254","journal-title":"Internist"},{"key":"1429_CR9","doi-asserted-by":"publisher","first-page":"c869","DOI":"10.1136\/bmj.c869","volume":"340","author":"D Moher","year":"2010","unstructured":"Moher\u00a0D, Hopewell\u00a0S, Schulz\u00a0KF et\u00a0al (2010) CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. Br Med\u00a0J 340:c869","journal-title":"Br Med J"},{"key":"1429_CR10","first-page":"152","volume":"15","author":"M Ordnung","year":"2021","unstructured":"Ordnung\u00a0M, Horstmann\u00a0A (2021) Die wissenschaftliche Evaluierung von zanadio \u2013 einem ganzheitlichen, digitalen Behandlungsprogramm f\u00fcr Menschen mit Adipositas. Adipositas 15:152\u2013153","journal-title":"Adipositas"},{"key":"1429_CR11","doi-asserted-by":"publisher","first-page":"e20","DOI":"10.1055\/s-0031-1272980","volume":"136","author":"MH Pittler","year":"2011","unstructured":"Pittler\u00a0MH, Bl\u00fcmle\u00a0A, Meerpohl\u00a0JJ et al (2011) CONSORT 2010: Aktualisierte Leitlinie f\u00fcr Berichte randomisierter Studien im Parallelgruppen-Design. Dtsch Med Wochenschr 136:e20\u2013e23","journal-title":"Dtsch Med Wochenschr"},{"key":"1429_CR12","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1186\/s13075-021-02500-3","volume":"23","author":"JG Richter","year":"2021","unstructured":"Richter\u00a0JG, Nannen\u00a0C, Chehab\u00a0G et al (2021) Mobile App-based documentation of patient-reported outcomes\u20143-months results from a\u00a0proof-of-concept study on modern rheumatology patient management. Arthritis Res Ther 23:121","journal-title":"Arthritis Res Ther"},{"key":"1429_CR13","doi-asserted-by":"publisher","first-page":"773836","DOI":"10.3389\/fmed.2021.773836","volume":"8","author":"JG Richter","year":"2021","unstructured":"Richter\u00a0JG, Wei\u00df\u00a0A, Bungartz\u00a0C et\u00a0al (2021) Mobile responsive app\u2014A useful additional tool for data collection in the German pregnancy register rhekiss? Front Med 8:773836","journal-title":"Front Med"},{"key":"1429_CR14","doi-asserted-by":"publisher","first-page":"726","DOI":"10.7326\/0003-4819-152-11-201006010-00232","volume":"152","author":"KF Schulz","year":"2010","unstructured":"Schulz\u00a0KF, Altman\u00a0DG, Moher\u00a0D (2010) CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials. Ann Intern Med 152:726\u2013732","journal-title":"Ann Intern Med"},{"key":"1429_CR15","doi-asserted-by":"publisher","first-page":"e200","DOI":"10.1016\/S2589-7500(21)00292-2","volume":"4","author":"AD Stern","year":"2022","unstructured":"Stern\u00a0AD, Br\u00f6nneke\u00a0J, Debatin\u00a0JF et al (2022) Advancing digital health applications: priorities for innovation in real-world evidence generation. Lancet Digit Health 4:e200\u2013e206","journal-title":"Lancet Digit Health"},{"key":"1429_CR16","first-page":"127","volume":"116","author":"JM Zill","year":"2019","unstructured":"Zill\u00a0JM, Christalle\u00a0E, Meyer\u00a0B et\u00a0al (2019) The effectiveness of an internet intervention aimed at reducing alcohol consumption in adults. Dtsch Arztebl Int 116:127\u2013133","journal-title":"Dtsch Arztebl Int"}],"container-title":["Die Innere Medizin"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-022-01429-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00108-022-01429-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-022-01429-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T17:28:55Z","timestamp":1669310935000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00108-022-01429-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,24]]},"references-count":16,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["1429"],"URL":"https:\/\/doi.org\/10.1007\/s00108-022-01429-2","relation":{},"ISSN":["2731-7080","2731-7099"],"issn-type":[{"value":"2731-7080","type":"print"},{"value":"2731-7099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,24]]},"assertion":[{"value":"5 October 2022","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 October 2022","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"I.R.\u00a0K\u00f6nig, M.\u00a0Mittermaier, C.\u00a0Sina, M.\u00a0Raspe, P.\u00a0Stais, T.\u00a0Gamst\u00e4tter, P.\u00a0Stachwitz, S.\u00a0Wolfrum, J.G.\u00a0Richter und M.\u00a0M\u00f6ckel geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autoren\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}