{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T00:45:20Z","timestamp":1771029920743,"version":"3.50.1"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T00:00:00Z","timestamp":1702598400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T00:00:00Z","timestamp":1702598400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum Leipzig"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Innere Medizin"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Deutschland gilt infolge intensiver Impf- und \u00dcberwachungsbem\u00fchen seit 2008 als frei von terrestrischer Tollwut. Reservoire der Lyssaviren EBLV\u20111 und EBLV\u20112 persistieren jedoch weiter in Fledermauskolonien und stellen somit ein potenzielles Infektionsrisiko dar. Wir berichten von einer Patientin, die einen Fledermausbiss im st\u00e4dtischen Umfeld erlitt. Bei der euthanasierten Fledermaus konnte das Europ\u00e4ische Fledermaus-Lyssavirus\u00a01 (EBLV-1) nachgewiesen werden. Wir f\u00fchrten eine aktive und passive Postexpositionsprophylaxe (PEP) durch. Dieses Fallbeispiel illustriert die anhaltende Tollwutinfektionsgefahr durch enge Fledermauskontakte in Deutschland und soll erstbehandelnde \u00c4rzte daf\u00fcr sensibilisieren, entsprechende Expositionsereignisse ernst zu nehmen und eine regelrechte PEP einschlie\u00dflich Applikation von Tollwutimmunglobulin durchzuf\u00fchren.<\/jats:p>","DOI":"10.1007\/s00108-023-01638-3","type":"journal-article","created":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T10:01:56Z","timestamp":1702634516000},"page":"608-611","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Postexpositionsprophylaxe nach Biss einer Breitfl\u00fcgelfledermaus mit Nachweis des Europ\u00e4ischen Fledermaus-Lyssavirus\u00a01 (EBLV-1)","Postexposure prophylaxis after bite of a\u00a0broad-winged bat with evidence of European bat lyssavirus\u00a01 (EBLV-1)"],"prefix":"10.1007","volume":"65","author":[{"given":"Jannik","family":"Fasse","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henning","family":"Trawinski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Hardt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"L\u00fcbbert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,12,15]]},"reference":[{"key":"1638_CR1","unstructured":"St\u00e4ndige Impfkommission beim Robert Koch-Institut (STIKO) (2023) Empfehlungen der St\u00e4ndigen Impfkommission beim Robert Koch-Institut 2023. https:\/\/www.rki.de\/DE\/Content\/Infekt\/EpidBull\/Archiv\/2023\/Ausgaben\/04_23.pdf. Zugegriffen: 11. Aug. 2023"},{"key":"1638_CR2","first-page":"201","volume":"26","author":"Robert Koch-Institut","year":"2023","unstructured":"Robert Koch-Institut (2023) Fledermaustollwut \u2013 Infektionsgefahr auch in Deutschland. Epidemiol Bull 26:201\u2013202","journal-title":"Epidemiol. Bull."},{"key":"1638_CR3","unstructured":"Robert Koch-Institut (2023) Ratgeber Tollwut. https:\/\/www.rki.de\/DE\/Content\/Infekt\/EpidBull\/Merkblaetter\/Ratgeber_Tollwut.html. Zugegriffen: 11. Aug. 2023"},{"key":"1638_CR4","doi-asserted-by":"publisher","first-page":"e119","DOI":"10.1017\/S0950268821000601","volume":"149","author":"P Meyerhoff","year":"2021","unstructured":"Meyerhoff\u00a0P, Manekeller\u00a0S, Saleh\u00a0N et\u00a0al (2021) Rabies post-exposure prophylaxis in Germany\u2014What are the challenges? Epidemiol Infect 149:e119. https:\/\/doi.org\/10.1017\/S0950268821000601","journal-title":"Epidemiol Infect"},{"key":"1638_CR5","unstructured":"Naturschutzbund Deutschland (NABU) (2023) Tierischer Besuch im Wohnzimmer: NABU-Tipps f\u00fcr den Umgang mit verirrten Flederm\u00e4usen. https:\/\/www.nabu.de\/tiere-und-pflanzen\/saeugetiere\/fledermaeuse\/aktiv-fuer-fledermaeuse\/01506.html. Zugegriffen: 25. Aug. 2023"},{"key":"1638_CR6","doi-asserted-by":"publisher","first-page":"e167","DOI":"10.1016\/S1473-3099(22)00641-7","volume":"23","author":"ER Whitehouse","year":"2023","unstructured":"Whitehouse\u00a0ER, Mandra\u00a0A, Bonwitt\u00a0J et\u00a0al (2023) Human rabies despite post-exposure prophylaxis: a\u00a0systematic review of fatal breakthrough infections after zoonotic exposures. Lancet Infect Dis 23:e167\u2013e174. https:\/\/doi.org\/10.1016\/S1473-3099(22)00641-7","journal-title":"Lancet Infect Dis"},{"key":"1638_CR7","doi-asserted-by":"publisher","first-page":"ciad098","DOI":"10.1093\/cid\/ciad098","volume":"29","author":"SM Holzbauer","year":"2023","unstructured":"Holzbauer\u00a0SM, Schrodt\u00a0CA, Prabhu\u00a0RM et\u00a0al (2023) Fatal Human Rabies Infection with Suspected Host-mediated Failure of Post-Exposure Prophylaxis Following a\u00a0Recognized Zoonotic Exposure-Minnesota, 2021. Clin Infect Dis 29:ciad98. https:\/\/doi.org\/10.1093\/cid\/ciad098","journal-title":"Clin Infect Dis"}],"container-title":["Die Innere Medizin"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-023-01638-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00108-023-01638-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-023-01638-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T16:02:44Z","timestamp":1716998564000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00108-023-01638-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,15]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["1638"],"URL":"https:\/\/doi.org\/10.1007\/s00108-023-01638-3","relation":{},"ISSN":["2731-7080","2731-7099"],"issn-type":[{"value":"2731-7080","type":"print"},{"value":"2731-7099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,15]]},"assertion":[{"value":"28 November 2023","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 December 2023","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"J.\u00a0Fasse, H.\u00a0Trawinski, M.\u00a0Hardt und C.\u00a0L\u00fcbbert geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patient\/-innen zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern\/Vertreterinnen eine schriftliche Einwilligung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}