{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T17:11:12Z","timestamp":1780333872527,"version":"3.54.1"},"reference-count":80,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Innere Medizin"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1007\/s00108-024-01835-8","type":"journal-article","created":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T11:34:04Z","timestamp":1737545644000},"page":"64-81","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Thrombopenie und h\u00e4molytische An\u00e4mie in der Akut- und Notfallmedizin","Thrombopenia and hemolytic anemia in acute and emergency medicine"],"prefix":"10.1007","volume":"66","author":[{"given":"Sebastian Alexander","family":"Potthoff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,22]]},"reference":[{"issue":"2","key":"1835_CR1","doi-asserted-by":"publisher","first-page":"300","DOI":"10.2215\/CJN.00620117","volume":"13","author":"V Brocklebank","year":"2018","unstructured":"Brocklebank\u00a0V, Wood\u00a0KM, Kavanagh\u00a0D (2018) Thrombotic Microangiopathy and the Kidney. Clin J Am Soc Nephrol 13(2):300\u2013317. https:\/\/doi.org\/10.2215\/CJN.00620117","journal-title":"Clin J Am Soc Nephrol"},{"key":"1835_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-801238-3.00069-6","volume-title":"Reference Module in Biomedical Sciences","author":"HM Tsai","year":"2014","unstructured":"Tsai\u00a0HM (2014) Microangiopathic Hemolytic Anemia. In: Reference Module in Biomedical Sciences. Elsevier, https:\/\/doi.org\/10.1016\/B978-0-12-801238-3.00069-6"},{"issue":"1","key":"1835_CR3","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s40164-021-00249-8","volume":"10","author":"E Gavriilaki","year":"2021","unstructured":"Gavriilaki\u00a0E, Ho\u00a0VT, Schwaeble\u00a0W, Dudler\u00a0T, Daha\u00a0M, Fujita\u00a0T, Jodele\u00a0S (2021) Role of the lectin pathway of complement in hematopoietic stem cell transplantation-associated endothelial injury and thrombotic microangiopathy. Exp Hematol Oncol 10(1):57. https:\/\/doi.org\/10.1186\/s40164-021-00249-8","journal-title":"Exp Hematol Oncol"},{"issue":"40","key":"1835_CR4","doi-asserted-by":"publisher","first-page":"1993","DOI":"10.1055\/s-0034-1370285","volume":"139","author":"M Starck","year":"2014","unstructured":"Starck\u00a0M, Wendtner\u00a0CM (2014) Thrombotic microangiopathies. Dtsch Med Wochenschr 139(40):1993\u20131996. https:\/\/doi.org\/10.1055\/s-0034-1370285","journal-title":"Dtsch Med Wochenschr"},{"issue":"2","key":"1835_CR5","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.jemermed.2017.02.018","volume":"53","author":"JJ Robertson","year":"2017","unstructured":"Robertson\u00a0JJ, Brem\u00a0E, Koyfman\u00a0A (2017) The Acute Hemolytic Anemias: The Importance of Emergency Diagnosis and Management. J\u00a0Emerg Med 53(2):202\u2013211. https:\/\/doi.org\/10.1016\/j.jemermed.2017.02.018","journal-title":"J Emerg Med"},{"key":"1835_CR6","doi-asserted-by":"publisher","first-page":"635670","DOI":"10.1155\/2015\/635670","volume":"2015","author":"W Barcellini","year":"2015","unstructured":"Barcellini\u00a0W, Fattizzo\u00a0B (2015) Clinical Applications of Hemolytic Markers in the Differential Diagnosis and Management of Hemolytic Anemia. Dis Markers 2015:635670. https:\/\/doi.org\/10.1155\/2015\/635670","journal-title":"Dis Markers"},{"issue":"12","key":"1835_CR7","doi-asserted-by":"publisher","first-page":"1370","DOI":"10.1007\/s11606-010-1430-x","volume":"25","author":"MS Sey","year":"2010","unstructured":"Sey\u00a0MS, Manlucu\u00a0J, Myers\u00a0KA (2010) Intravascular hemolysis secondary to aorto-atrial fistula presenting as red urine. J\u00a0Gen Intern Med 25(12):1370\u20131374. https:\/\/doi.org\/10.1007\/s11606-010-1430-x","journal-title":"J Gen Intern Med"},{"issue":"6","key":"1835_CR8","doi-asserted-by":"publisher","first-page":"855","DOI":"10.2174\/1871530320666191230141110","volume":"20","author":"AA Khan","year":"2020","unstructured":"Khan\u00a0AA, Allemailem\u00a0KS, Alhumaydhi\u00a0FA, Gowder\u00a0SJT, Rahmani\u00a0AH (2020) The Biochemical and Clinical Perspectives of Lactate Dehydrogenase: An Enzyme of Active Metabolism. Endocr Metab Immune Disord Drug Targets 20(6):855\u2013868. https:\/\/doi.org\/10.2174\/1871530320666191230141110","journal-title":"Endocr Metab Immune Disord Drug Targets"},{"issue":"8","key":"1835_CR9","doi-asserted-by":"publisher","first-page":"2553","DOI":"10.31557\/APJCP.2022.23.8.2553","volume":"23","author":"W Barbi","year":"2022","unstructured":"Barbi\u00a0W, Purohit\u00a0BM (2022) Serum Lactate Dehydrogenase Enzyme as a\u00a0Tumor Marker in Potentially Malignant Disorders: A\u00a0Systematic Review and Meta-Analysis. Asian Pac J Cancer Prev 23(8):2553\u20132559. https:\/\/doi.org\/10.31557\/APJCP.2022.23.8.2553","journal-title":"Asian Pac J Cancer Prev"},{"key":"1835_CR10","doi-asserted-by":"crossref","unstructured":"Shipman AR, Bahrani S, Shipman KE (2024) Investigative algorithms for disorders affecting plasma lactate dehydrogenase: a\u00a0narrative review. J\u00a0Lab Precis Med 9:","DOI":"10.21037\/jlpm-23-65"},{"issue":"3","key":"1835_CR11","doi-asserted-by":"publisher","first-page":"e0283380","DOI":"10.1371\/journal.pone.0283380","volume":"18","author":"A Frenkel","year":"2023","unstructured":"Frenkel\u00a0A, Shiloh\u00a0A, Azulay\u00a0B, Novack\u00a0V, Klein\u00a0M, Dreiher\u00a0J (2023) The role of lactate dehydrogenase in hospitalized patients, comparing those with pulmonary versus non-pulmonary infections: A\u00a0nationwide study. PLoS ONE 18(3):e283380. https:\/\/doi.org\/10.1371\/journal.pone.0283380","journal-title":"PLoS ONE"},{"issue":"2","key":"1835_CR12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.18332\/pne\/186710","volume":"37","author":"EN Dimitrov","year":"2024","unstructured":"Dimitrov\u00a0EN, Valchev\u00a0D, Minkov\u00a0G, Enchev\u00a0E, Yovtchev\u00a0Y (2024) Serum lactate dehydrogenase improves significantly quick-Sequential Organ Failure Assessment score as a\u00a0predictor of mortality in patients with thoracic empyema: A\u00a0retrospective analysis. Pneumon 37(2):1\u20138. https:\/\/doi.org\/10.18332\/pne\/186710","journal-title":"Pneumon"},{"issue":"3","key":"1835_CR13","doi-asserted-by":"publisher","first-page":"213","DOI":"10.5152\/eurasianjmed.2021.21149","volume":"54","author":"Z Jamil","year":"2022","unstructured":"Jamil\u00a0Z, Samreen\u00a0S, Mukhtar\u00a0B, Khaliq\u00a0M, Abbasi\u00a0SM, Ahmed\u00a0J, Hussain\u00a0T (2022) The Clinical Implementation of NEWS, SOFA, and CALL Scores in Predicting the In-Hospital Outcome of Severe or Critical COVID-19\u00a0Patients. Eurasian J Med 54(3):213\u2013218. https:\/\/doi.org\/10.5152\/eurasianjmed.2021.21149","journal-title":"Eurasian J Med"},{"issue":"2","key":"1835_CR14","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1055\/s-0044-1786005","volume":"11","author":"JY Zhang","year":"2024","unstructured":"Zhang\u00a0JY, Yan\u00a0ZS, Sun\u00a0XJ, Liu\u00a0YZ, Yin\u00a0YK, Su\u00a0MH, Li\u00a0QL, Mi\u00a0YC, Li\u00a0DP (2024) Association between Serum Lactate Dehydrogenase Level and 30-day Mortality in Patients with Intracranial Hemorrhage with Acute Leukemia in the Induction Phase: A\u00a0Cohort Study. Glob Med Genet 11(2):142\u2013149. https:\/\/doi.org\/10.1055\/s-0044-1786005","journal-title":"Glob Med Genet"},{"issue":"1","key":"1835_CR15","doi-asserted-by":"publisher","first-page":"e24","DOI":"10.22037\/aaem.v9i1.1096","volume":"9","author":"H Heidari Beigvand","year":"2021","unstructured":"Heidari Beigvand\u00a0H, Heidari\u00a0K, Hashemi\u00a0B, Saberinia\u00a0A (2021) The Value of Lactate Dehydrogenase in Predicting Rhabdomyolysis-Induced Acute Renal Failure; a\u00a0Narrative Review. Arch Acad Emerg Med 9(1):e24. https:\/\/doi.org\/10.22037\/aaem.v9i1.1096","journal-title":"Arch Acad Emerg Med"},{"issue":"3","key":"1835_CR16","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1093\/jalm\/jfac137","volume":"8","author":"JR Price","year":"2023","unstructured":"Price\u00a0JR, Hagrass\u00a0H, Filip\u00a0AB, McGill\u00a0MR (2023) LDH and the MELD-LDH in Severe Acute Liver Injury and Acute Liver Failure: Preliminary Confirmation of a\u00a0Novel Prognostic Score for Risk Stratification. J\u00a0Appl Lab Med 8(3):504\u2013513. https:\/\/doi.org\/10.1093\/jalm\/jfac137","journal-title":"J Appl Lab Med"},{"issue":"19","key":"1835_CR17","doi-asserted-by":"publisher","first-page":"1909","DOI":"10.1001\/jama.1980.03300450023014","volume":"243","author":"A Marchand","year":"1980","unstructured":"Marchand\u00a0A, Galen\u00a0RS, Van Lente\u00a0F (1980) The predictive value of serum haptoglobin in hemolytic disease. JAMA 243(19):1909\u20131911","journal-title":"JAMA"},{"key":"1835_CR18","volume-title":"Unconjugated Hyperbilirubinemia","author":"AKT Singh","year":"2024","unstructured":"Singh\u00a0AKT, Jialal\u00a0I (2024) Unconjugated Hyperbilirubinemia. StatPearls Publishing, Treasure Island (FL)"},{"key":"1835_CR19","volume-title":"Hemolytic Anemia","author":"CPJ Baldwin","year":"2024","unstructured":"Baldwin\u00a0CPJ, Olarewaju\u00a0O (2024) Hemolytic Anemia. StatPearls Publishing, Treasure Island (FL)"},{"issue":"3","key":"1835_CR20","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1111\/ijlh.14260","volume":"46","author":"Z Zhang","year":"2024","unstructured":"Zhang\u00a0Z, Yang\u00a0S, Wang\u00a0X (2024) Schistocyte detection in artificial intelligence age. Int J Lab Hematol 46(3):427\u2013433. https:\/\/doi.org\/10.1111\/ijlh.14260","journal-title":"Int J Lab Hematol"},{"issue":"6","key":"1835_CR21","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1111\/ijlh.13682","volume":"43","author":"G Zini","year":"2021","unstructured":"Zini\u00a0G, d\u2019Onofrio\u00a0G, Erber\u00a0WN, Lee\u00a0SH, Nagai\u00a0Y, Basak\u00a0GW, Lesesve\u00a0JF, International Council for Standardization in H (2021) 2021 update of the 2012 ICSH Recommendations for identification, diagnostic value, and quantitation of schistocytes: Impact and revisions. Int J Lab Hematol 43(6):1264\u20131271. https:\/\/doi.org\/10.1111\/ijlh.13682","journal-title":"Int J Lab Hematol"},{"issue":"2","key":"1835_CR22","doi-asserted-by":"publisher","first-page":"305","DOI":"10.5858\/arpa.2015-0444-RS","volume":"141","author":"V Parker","year":"2017","unstructured":"Parker\u00a0V, Tormey\u00a0CA (2017) The Direct Antiglobulin Test: Indications, Interpretation, and Pitfalls. Arch Pathol Lab Med 141(2):305\u2013310. https:\/\/doi.org\/10.5858\/arpa.2015-0444-RS","journal-title":"Arch Pathol Lab Med"},{"issue":"2","key":"1835_CR23","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.annepidem.2005.06.052","volume":"16","author":"JB Segal","year":"2006","unstructured":"Segal\u00a0JB, Moliterno\u00a0AR (2006) Platelet counts differ by sex, ethnicity, and age in the United States. Ann Epidemiol 16(2):123\u2013130. https:\/\/doi.org\/10.1016\/j.annepidem.2005.06.052","journal-title":"Ann Epidemiol"},{"issue":"4","key":"1835_CR24","first-page":"379","volume":"18","author":"CP Teo","year":"1989","unstructured":"Teo\u00a0CP, Kueh\u00a0YK (1989) Incidence of thrombocytopenia in an acute care hospital. Ann Acad Med Singap 18(4):379\u2013381","journal-title":"Ann Acad Med Singap"},{"issue":"1","key":"1835_CR25","doi-asserted-by":"publisher","first-page":"282","DOI":"10.12669\/pjms.35.1.19","volume":"35","author":"Z Ostadi","year":"2019","unstructured":"Ostadi\u00a0Z, Shadvar\u00a0K, Sanaie\u00a0S, Mahmoodpoor\u00a0A, Saghaleini\u00a0SH (2019) Thrombocytopenia in the intensive care unit. Pak J Med Sci 35(1):282\u2013287. https:\/\/doi.org\/10.12669\/pjms.35.1.19","journal-title":"Pak J Med Sci"},{"issue":"11","key":"1835_CR26","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1007\/s00134-023-07225-2","volume":"49","author":"CT Anthon","year":"2023","unstructured":"Anthon\u00a0CT, Pene\u00a0F, Perner\u00a0A, Azoulay\u00a0E, Puxty\u00a0K, Van De Louw\u00a0A, Barratt-Due\u00a0A, Chawla\u00a0S, Castro\u00a0P, Povoa\u00a0P, Coelho\u00a0L, Metaxa\u00a0V, Kochanek\u00a0M, Liebregts\u00a0T, Kander\u00a0T, Hastbacka\u00a0J, Andreasen\u00a0JB, Peju\u00a0E, Nielsen\u00a0LB, Hvas\u00a0CL, Dufranc\u00a0E, Canet\u00a0E, Lundqvist\u00a0L, Wright\u00a0CJ, Schmidt\u00a0J, Uhel\u00a0F, Ait-Oufella\u00a0H, Krag\u00a0M, Cos Badia\u00a0E, Diaz-Lagares\u00a0C, Menat\u00a0S, Voiriot\u00a0G, Clausen\u00a0NE, Lorentzen\u00a0K, Kvale\u00a0R, Hildebrandt\u00a0T, Holten\u00a0AR, Strand\u00a0K, Tzalavras\u00a0A, Bestle\u00a0MH, Klepstad\u00a0P, Fernandez\u00a0S, Vimpere\u00a0D, Paulino\u00a0C, Graca\u00a0C, Lueck\u00a0C, Juhl\u00a0CS, Costa\u00a0C, Badstolokken\u00a0PM, Miranda\u00a0T, Ledo\u00a0LSA, Sousa Torres\u00a0JC, Granholm\u00a0A, Moller\u00a0MH, Russell\u00a0L, on behalf of the P\u2011ICUC, the Nine ISG (2023) Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU). Intensive Care Med 49(11):1327\u20131338. https:\/\/doi.org\/10.1007\/s00134-023-07225-2","journal-title":"Intensive Care Med"},{"key":"1835_CR27","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1182\/asheducation-2012.1.191","volume":"2012","author":"R Stasi","year":"2012","unstructured":"Stasi\u00a0R (2012) How to approach thrombocytopenia. Hematology Am Soc Hematol Educ Program 2012:191\u2013197. https:\/\/doi.org\/10.1182\/asheducation-2012.1.191","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"1835_CR28","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1182\/asheducation-2010.1.135","volume":"2010","author":"A Greinacher","year":"2010","unstructured":"Greinacher\u00a0A, Selleng\u00a0K (2010) Thrombocytopenia in the intensive care unit patient. Hematology Am Soc Hematol Educ Program 2010:135\u2013143. https:\/\/doi.org\/10.1182\/asheducation-2010.1.135","journal-title":"Hematology Am Soc Hematol Educ Program"},{"issue":"6","key":"1835_CR29","first-page":"612","volume":"85","author":"RL Gauer","year":"2012","unstructured":"Gauer\u00a0RL, Braun\u00a0MM (2012) Thrombocytopenia. Am Fam Physician 85(6):612\u2013622","journal-title":"Am Fam Physician"},{"issue":"8","key":"1835_CR30","doi-asserted-by":"publisher","first-page":"e27718","DOI":"10.7759\/cureus.27718","volume":"14","author":"RK Santoshi","year":"2022","unstructured":"Santoshi\u00a0RK, Patel\u00a0R, Patel\u00a0NS, Bansro\u00a0V, Chhabra\u00a0G (2022) A Comprehensive Review of Thrombocytopenia With a\u00a0Spotlight on Intensive Care Patients. Cureus 14(8):e27718. https:\/\/doi.org\/10.7759\/cureus.27718","journal-title":"Cureus"},{"issue":"6","key":"1835_CR31","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/j.ejim.2013.05.007","volume":"24","author":"SR Cataland","year":"2013","unstructured":"Cataland\u00a0SR, Wu\u00a0HM (2013) Atypical hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: clinically differentiating the thrombotic microangiopathies. Eur J Intern Med 24(6):486\u2013491. https:\/\/doi.org\/10.1016\/j.ejim.2013.05.007","journal-title":"Eur J Intern Med"},{"issue":"2","key":"1835_CR32","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/j.mcna.2016.09.010","volume":"101","author":"Shatzel","year":"2017","unstructured":"Shatzel JJ, Taylor JA (2017) Syndromes of Thrombotic Microangiopathy. Med Clin North Am 101 (2):395-415. doi:10.1016\/j.mcna.2016.09.010","journal-title":"Med Clin North Am"},{"issue":"4","key":"1835_CR33","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/j.rdc.2018.06.010","volume":"44","author":"Barbar","year":"2018","unstructured":"Babar F, Cohen SD (2018) Thrombotic Microangiopathies with Rheumatologic Involvement. Rheum Dis Clin North Am 44 (4):635-649. doi:10.1016\/j.rdc.2018.06.010","journal-title":"Rheum Dis Clin North Am"},{"issue":"4","key":"1835_CR34","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1182\/blood-2014-11-611335","volume":"125","author":"Al-Nouri","year":"2015","unstructured":"Al-Nouri ZL, Reese JA, Terrell DR, Vesely SK, George JN (2015) Drug-induced thrombotic microangiopathy: a systematic review of published reports. Blood 125 (4):616-618. doi:10.1182\/blood-2014-11-611335","journal-title":"Blood"},{"issue":"2","key":"1835_CR35","doi-asserted-by":"publisher","first-page":"368504211025927","DOI":"10.1177\/00368504211025927","volume":"104","author":"Alam","year":"2021","unstructured":"Alam W (2021) COVID-19 vaccine-induced immune thrombotic thrombocytopenia: A review of the potential mechanisms and proposed management. Sci Prog 104 (2):368504211025927. doi:10.1177\/00368504211025927","journal-title":"Sci Prog"},{"issue":"11","key":"1835_CR36","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.1007\/s00134-019-05736-5","volume":"45","author":"E Azoulay","year":"2019","unstructured":"Azoulay\u00a0E, Bauer\u00a0PR, Mariotte\u00a0E, Russell\u00a0L, Knoebl\u00a0P, Martin-Loeches\u00a0I, Pene\u00a0F, Puxty\u00a0K, Povoa\u00a0P, Barratt-Due\u00a0A, Garnacho-Montero\u00a0J, Wendon\u00a0J, Munshi\u00a0L, Benoit\u00a0D, von Bergwelt-Baildon\u00a0M, Maggiorini\u00a0M, Coppo\u00a0P, Cataland\u00a0S, Veyradier\u00a0A, Van de Nine\u2011i LAI (2019) Expert statement on the ICU management of patients with thrombotic thrombocytopenic purpura. Intensive Care Med 45(11):1518\u20131539. https:\/\/doi.org\/10.1007\/s00134-019-05736-5","journal-title":"Intensive Care Med"},{"key":"1835_CR37","doi-asserted-by":"publisher","first-page":"2233","DOI":"10.2147\/JMDH.S245620","volume":"16","author":"K Yerigeri","year":"2023","unstructured":"Yerigeri\u00a0K, Kadatane\u00a0S, Mongan\u00a0K, Boyer\u00a0O, Burke\u00a0LLG, Sethi\u00a0SK, Licht\u00a0C, Raina\u00a0R (2023) Atypical Hemolytic-Uremic Syndrome: Genetic Basis, Clinical Manifestations, and a\u00a0Multidisciplinary Approach to Management. J\u00a0Multidiscip Healthc 16:2233\u20132249. https:\/\/doi.org\/10.2147\/JMDH.S245620","journal-title":"J Multidiscip Healthc"},{"issue":"3","key":"1835_CR38","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1111\/j.1365-2141.2012.09167.x","volume":"158","author":"M Scully","year":"2012","unstructured":"Scully\u00a0M, Hunt\u00a0BJ, Benjamin\u00a0S, Liesner\u00a0R, Rose\u00a0P, Peyvandi\u00a0F, Cheung\u00a0B, Machin\u00a0SJ, British Committee for Standards in H (2012) Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies. Br J Haematol 158(3):323\u2013335. https:\/\/doi.org\/10.1111\/j.1365-2141.2012.09167.x","journal-title":"Br J Haematol"},{"key":"1835_CR39","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10030536","author":"S Sukumar","year":"2021","unstructured":"Sukumar\u00a0S, Lammle\u00a0B, Cataland\u00a0SR (2021) Thrombotic Thrombocytopenic Purpura: Pathophysiology, Diagnosis, and Management. J\u00a0Clin Med. https:\/\/doi.org\/10.3390\/jcm10030536","journal-title":"J Clin Med"},{"issue":"1","key":"1835_CR40","doi-asserted-by":"publisher","first-page":"36","DOI":"10.5045\/br.2023.2022133","volume":"58","author":"CCK Liam","year":"2023","unstructured":"Liam\u00a0CCK, Tiao\u00a0JY, Yap\u00a0YY, Lee\u00a0YL, Sathar\u00a0J, McRae\u00a0S, Davis\u00a0A, Curnow\u00a0J, Bird\u00a0R, Choi\u00a0P, Angchaisuksiri\u00a0P, Tien\u00a0SL, Lam\u00a0JCM, Oh\u00a0D, Kim\u00a0JS, Yoon\u00a0SS, Wong\u00a0RS, Lauren\u00a0C, Merriman\u00a0EG, Enjeti\u00a0A, Smith\u00a0M, Baker\u00a0RI (2023) Validating lactate dehydrogenase (LDH) as a\u00a0component of the PLASMIC predictive tool (PLASMIC-LDH). Blood Res 58(1):36\u201341. https:\/\/doi.org\/10.5045\/br.2023.2022133","journal-title":"Blood Res"},{"issue":"4","key":"1835_CR41","doi-asserted-by":"publisher","first-page":"e157","DOI":"10.1016\/S2352-3026(17)30026-1","volume":"4","author":"PK Bendapudi","year":"2017","unstructured":"Bendapudi\u00a0PK, Hurwitz\u00a0S, Fry\u00a0A, Marques\u00a0MB, Waldo\u00a0SW, Li\u00a0A, Sun\u00a0L, Upadhyay\u00a0V, Hamdan\u00a0A, Brunner\u00a0AM, Gansner\u00a0JM, Viswanathan\u00a0S, Kaufman\u00a0RM, Uhl\u00a0L, Stowell\u00a0CP, Dzik\u00a0WH, Makar\u00a0RS (2017) Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a\u00a0cohort study. Lancet Haematol 4(4):e157\u2013e164. https:\/\/doi.org\/10.1016\/S2352-3026(17)30026-1","journal-title":"Lancet Haematol"},{"key":"1835_CR42","doi-asserted-by":"publisher","unstructured":"Coppo\u00a0P, Schwarzinger\u00a0M, Buffet\u00a0M, Wynckel\u00a0A, Clabault\u00a0K, Presne\u00a0C, Poullin\u00a0P, Malot\u00a0S, Vanhille\u00a0P, Azoulay\u00a0E, Galicier\u00a0L, Lemiale\u00a0V, Mira\u00a0JP, Ridel\u00a0C, Rondeau\u00a0E, Pourrat\u00a0J, Girault\u00a0S, Bordessoule\u00a0D, Saheb\u00a0S, Ramakers\u00a0M, Hamidou\u00a0M, Vernant\u00a0JP, Guidet\u00a0B, Wolf\u00a0M, Veyradier\u00a0A, French Reference Center for Thrombotic M (2010) Predictive features of severe acquired ADAMTS13 deficiency in idiopathic thrombotic microangiopathies: the French TMA reference center experience. PLoS One 5(4):e10208. https:\/\/doi.org\/10.1371\/journal.pone.0010208","DOI":"10.1371\/journal.pone.0010208"},{"key":"1835_CR43","doi-asserted-by":"publisher","DOI":"10.3390\/toxins15010010","author":"Y Liu","year":"2022","unstructured":"Liu\u00a0Y, Thaker\u00a0H, Wang\u00a0C, Xu\u00a0Z, Dong\u00a0M (2022) Diagnosis and Treatment for Shiga Toxin-Producing Escherichia coli Associated Hemolytic Uremic Syndrome. Toxins. https:\/\/doi.org\/10.3390\/toxins15010010","journal-title":"Toxins"},{"key":"1835_CR44","doi-asserted-by":"publisher","first-page":"813637","DOI":"10.3389\/fmolb.2022.813637","volume":"9","author":"AB Celi","year":"2022","unstructured":"Celi\u00a0AB, Goldstein\u00a0J, Rosato-Siri\u00a0MV, Pinto\u00a0A (2022) Role of Globotriaosylceramide in Physiology and Pathology. Front Mol Biosci 9:813637. https:\/\/doi.org\/10.3389\/fmolb.2022.813637","journal-title":"Front Mol Biosci"},{"issue":"2","key":"1835_CR45","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.kint.2018.02.029","volume":"94","author":"F Schaefer","year":"2018","unstructured":"Schaefer\u00a0F, Ardissino\u00a0G, Ariceta\u00a0G, Fakhouri\u00a0F, Scully\u00a0M, Isbel\u00a0N, Lommele\u00a0A, Kupelian\u00a0V, Gasteyger\u00a0C, Greenbaum\u00a0LA, Johnson\u00a0S, Ogawa\u00a0M, Licht\u00a0C, Vande Walle\u00a0J, Fremeaux-Bacchi\u00a0V, Global a HUSR (2018) Clinical and genetic predictors of atypical hemolytic uremic syndrome phenotype and outcome. Kidney Int 94(2):408\u2013418. https:\/\/doi.org\/10.1016\/j.kint.2018.02.029","journal-title":"Kidney Int"},{"issue":"8","key":"1835_CR46","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1007\/s00108-018-0455-9","volume":"59","author":"M Knoop","year":"2018","unstructured":"Knoop\u00a0M, Haller\u00a0H, Menne\u00a0J (2018) Human genetics in atypical hemolytic uremic syndrome-its role in diagnosis and treatment. Internist 59(8):799\u2013804. https:\/\/doi.org\/10.1007\/s00108-018-0455-9","journal-title":"Internist"},{"issue":"1","key":"1835_CR47","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1007\/s40620-016-0288-3","volume":"30","author":"JV Walle","year":"2017","unstructured":"Walle\u00a0JV, Delmas\u00a0Y, Ardissino\u00a0G, Wang\u00a0J, Kincaid\u00a0JF, Haller\u00a0H (2017) Improved renal recovery in patients with atypical hemolytic uremic syndrome following rapid initiation of eculizumab treatment. J\u00a0Nephrol 30(1):127\u2013134. https:\/\/doi.org\/10.1007\/s40620-016-0288-3","journal-title":"J Nephrol"},{"issue":"1","key":"1835_CR48","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.pcl.2018.09.011","volume":"66","author":"EM Cody","year":"2019","unstructured":"Cody\u00a0EM, Dixon\u00a0BP (2019) Hemolytic Uremic Syndrome. Pediatr Clin North Am 66(1):235\u2013246. https:\/\/doi.org\/10.1016\/j.pcl.2018.09.011","journal-title":"Pediatr Clin North Am"},{"issue":"1","key":"1835_CR49","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1182\/asheducation-2017.1.632","volume":"2017","author":"JL Winters","year":"2017","unstructured":"Winters\u00a0JL (2017) Plasma exchange in thrombotic microangiopathies (TMAs) other than thrombotic thrombocytopenic purpura (TTP). Hematology Am Soc Hematol Educ Program 2017(1):632\u2013638. https:\/\/doi.org\/10.1182\/asheducation-2017.1.632","journal-title":"Hematology Am Soc Hematol Educ Program"},{"issue":"50","key":"1835_CR50","doi-asserted-by":"publisher","first-page":"e18308","DOI":"10.1097\/MD.0000000000018308","volume":"98","author":"J Lu","year":"2019","unstructured":"Lu\u00a0J, Zhang\u00a0L, Xia\u00a0C, Tao\u00a0Y (2019) Complications of therapeutic plasma exchange: A\u00a0retrospective study of 1201 procedures in 435 children. Medicine 98(50):e18308. https:\/\/doi.org\/10.1097\/MD.0000000000018308","journal-title":"Medicine"},{"issue":"11","key":"1835_CR51","doi-asserted-by":"publisher","first-page":"e0988","DOI":"10.1097\/CCE.0000000000000988","volume":"5","author":"M Francois","year":"2023","unstructured":"Francois\u00a0M, Daubin\u00a0D, Menouche\u00a0D, Gaillet\u00a0A, Provoost\u00a0J, Trusson\u00a0R, Arrestier\u00a0R, Hequet\u00a0O, Richard\u00a0JC, Moranne\u00a0O, Larcher\u00a0R, Klouche\u00a0K (2023) Adverse Events and Infectious Complications in the Critically Ill Treated by Plasma Exchange: A\u00a0Five-Year Multicenter Cohort Study. Crit Care Explor 5(11):e988. https:\/\/doi.org\/10.1097\/CCE.0000000000000988","journal-title":"Crit Care Explor"},{"issue":"4","key":"1835_CR52","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1056\/NEJMoa1806311","volume":"380","author":"M Scully","year":"2019","unstructured":"Scully\u00a0M, Cataland\u00a0SR, Peyvandi\u00a0F, Coppo\u00a0P, Knobl\u00a0P, Kremer Hovinga\u00a0JA, Metjian\u00a0A, de la Rubia\u00a0J, Pavenski\u00a0K, Callewaert\u00a0F, Biswas\u00a0D, De Winter\u00a0H, Zeldin\u00a0RK, Investigators\u00a0H (2019) Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura. N\u00a0Engl J Med 380(4):335\u2013346. https:\/\/doi.org\/10.1056\/NEJMoa1806311","journal-title":"N Engl J Med"},{"issue":"6","key":"1835_CR53","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1182\/blood.2020008021","volume":"137","author":"P Coppo","year":"2021","unstructured":"Coppo\u00a0P, Bubenheim\u00a0M, Azoulay\u00a0E, Galicier\u00a0L, Malot\u00a0S, Bige\u00a0N, Poullin\u00a0P, Provot\u00a0F, Martis\u00a0N, Presne\u00a0C, Moranne\u00a0O, Benainous\u00a0R, Dossier\u00a0A, Seguin\u00a0A, Hie\u00a0M, Wynckel\u00a0A, Delmas\u00a0Y, Augusto\u00a0JF, Perez\u00a0P, Rieu\u00a0V, Barbet\u00a0C, Lhote\u00a0F, Ulrich\u00a0M, Rumpler\u00a0AC, de Witte\u00a0S, Krummel\u00a0T, Veyradier\u00a0A, Benhamou\u00a0Y (2021) A regimen with caplacizumab, immunosuppression, and plasma exchange prevents unfavorable outcomes in immune-mediated TTP. Blood 137(6):733\u2013742. https:\/\/doi.org\/10.1182\/blood.2020008021","journal-title":"Blood"},{"issue":"17","key":"1835_CR54","doi-asserted-by":"publisher","first-page":"1584","DOI":"10.1056\/NEJMoa2314793","volume":"390","author":"M Scully","year":"2024","unstructured":"Scully\u00a0M, Antun\u00a0A, Cataland\u00a0SR, Coppo\u00a0P, Dossier\u00a0C, Biebuyck\u00a0N, Hassenpflug\u00a0WA, Kentouche\u00a0K, Knobl\u00a0P, Kremer Hovinga\u00a0JA, Lopez-Fernandez\u00a0MF, Matsumoto\u00a0M, Ortel\u00a0TL, Windyga\u00a0J, Bhattacharya\u00a0I, Cronin\u00a0M, Li\u00a0H, Mellgard\u00a0B, Patel\u00a0M, Patwari\u00a0P, Xiao\u00a0S, Zhang\u00a0P, Wang\u00a0LT, c TTPPSI (2024) Recombinant ADAMTS13 in Congenital Thrombotic Thrombocytopenic Purpura. N\u00a0Engl J Med 390(17):1584\u20131596. https:\/\/doi.org\/10.1056\/NEJMoa2314793","journal-title":"N Engl J Med"},{"issue":"14","key":"1835_CR55","doi-asserted-by":"publisher","first-page":"3718","DOI":"10.1182\/bloodadvances.2024013265","volume":"8","author":"S Dadoun","year":"2024","unstructured":"Dadoun\u00a0S, Adam\u00a0K, Hensch\u00a0L, Boyd\u00a0TK, Ibrahimi\u00a0S, George\u00a0JN, Scully\u00a0M, Sukumar\u00a0S (2024) Recombinant ADAMTS13: an effective rescue therapy for acute cTTP during pregnancy. Blood Adv 8(14):3718\u20133720. https:\/\/doi.org\/10.1182\/bloodadvances.2024013265","journal-title":"Blood Adv"},{"issue":"1","key":"1835_CR56","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1007\/s40124-020-00208-7","volume":"8","author":"VJ Harkins","year":"2020","unstructured":"Harkins\u00a0VJ, McAllister\u00a0DA, Reynolds\u00a0BC (2020) Shiga-Toxin E.\u00a0coli Hemolytic Uremic Syndrome: Review of Management and Long-term Outcome. Curr Pediatr Rep 8(1):16\u201325. https:\/\/doi.org\/10.1007\/s40124-020-00208-7","journal-title":"Curr Pediatr Rep"},{"issue":"9","key":"1835_CR57","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1681\/ASN.0000000000000182","volume":"34","author":"A Garnier","year":"2023","unstructured":"Garnier\u00a0A, Brochard\u00a0K, Kwon\u00a0T, Sellier-Leclerc\u00a0AL, Lahoche\u00a0A, Launay\u00a0EA, Nobili\u00a0F, Caillez\u00a0M, Taque\u00a0S, Harambat\u00a0J, Michel-Bourdat\u00a0G, Guigonis\u00a0V, Fila\u00a0M, Cloarec\u00a0S, Djamal-Dine\u00a0D, de Parscaux\u00a0L, Allard\u00a0L, Salomon\u00a0R, Ulinski\u00a0T, Fremeaux-Bacchi\u00a0V, Morin\u00a0C, Olivier-Abbal\u00a0P, Colineaux\u00a0H, Auriol\u00a0F, Arnaud\u00a0C, Kieffer\u00a0I, Brusq\u00a0C (2023) Efficacy and Safety of Eculizumab in Pediatric Patients Affected by Shiga Toxin-Related Hemolytic and Uremic Syndrome: A\u00a0Randomized, Placebo-Controlled Trial. J\u00a0Am Soc Nephrol 34(9):1561\u20131573. https:\/\/doi.org\/10.1681\/ASN.0000000000000182","journal-title":"J Am Soc Nephrol"},{"issue":"9","key":"1835_CR58","doi-asserted-by":"publisher","first-page":"1470","DOI":"10.1182\/blood-2014-10-605493","volume":"125","author":"R Goel","year":"2015","unstructured":"Goel\u00a0R, Ness\u00a0PM, Takemoto\u00a0CM, Krishnamurti\u00a0L, King\u00a0KE, Tobian\u00a0AA (2015) Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality. Blood 125(9):1470\u20131476. https:\/\/doi.org\/10.1182\/blood-2014-10-605493","journal-title":"Blood"},{"issue":"7","key":"1835_CR59","doi-asserted-by":"publisher","first-page":"1798","DOI":"10.1111\/trf.13041","volume":"55","author":"E Riviere","year":"2015","unstructured":"Riviere\u00a0E, Saint-Leger\u00a0M, James\u00a0C, Delmas\u00a0Y, Clouzeau\u00a0B, Bui\u00a0N, Vital\u00a0A, Coppo\u00a0P, Gruson\u00a0D, Boyer\u00a0A (2015) Platelet transfusion and catheter insertion for plasma exchange in patients with thrombotic thrombocytopenic purpura and a\u00a0low platelet count. Transfusion 55(7):1798\u20131802. https:\/\/doi.org\/10.1111\/trf.13041","journal-title":"Transfusion"},{"issue":"6","key":"1835_CR60","doi-asserted-by":"publisher","first-page":"E127","DOI":"10.1002\/ajh.23997","volume":"90","author":"Y Benhamou","year":"2015","unstructured":"Benhamou\u00a0Y, Baudel\u00a0JL, Wynckel\u00a0A, Galicier\u00a0L, Azoulay\u00a0E, Provot\u00a0F, Pene\u00a0F, Mira\u00a0JP, Presne\u00a0C, Poullin\u00a0P, Halimi\u00a0JM, Riviere\u00a0E, Kanouni\u00a0T, Seguin\u00a0A, Mousson\u00a0C, Servais\u00a0A, Bordessoule\u00a0D, Perez\u00a0P, Hamidou\u00a0M, Chauveau\u00a0D, Veyradier\u00a0A, Coppo\u00a0P (2015) Are platelet transfusions harmful in acquired thrombotic thrombocytopenic purpura at the acute phase? Experience of the French thrombotic microangiopathies reference center. Am J Hematol 90(6):E127\u2013E129. https:\/\/doi.org\/10.1002\/ajh.23997","journal-title":"Am J Hematol"},{"issue":"19","key":"1835_CR61","doi-asserted-by":"publisher","first-page":"2103","DOI":"10.1182\/blood.2020005221","volume":"136","author":"F Fakhouri","year":"2020","unstructured":"Fakhouri\u00a0F, Scully\u00a0M, Provot\u00a0F, Blasco\u00a0M, Coppo\u00a0P, Noris\u00a0M, Paizis\u00a0K, Kavanagh\u00a0D, Pene\u00a0F, Quezada\u00a0S, Hertig\u00a0A, Kissling\u00a0S, O\u2019Brien\u00a0P, Delmas\u00a0Y, Alberio\u00a0L, Winer\u00a0N, Veyradier\u00a0A, Cataland\u00a0S, Fremeaux-Bacchi\u00a0V, Loirat\u00a0C, Remuzzi\u00a0G, Tsatsaris\u00a0V (2020) Management of thrombotic microangiopathy in pregnancy and postpartum: report from an international working group. Blood 136(19):2103\u20132117. https:\/\/doi.org\/10.1182\/blood.2020005221","journal-title":"Blood"},{"issue":"7","key":"1835_CR62","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1002\/ajh.23455","volume":"88","author":"S Chaturvedi","year":"2013","unstructured":"Chaturvedi\u00a0S, Carcioppolo\u00a0D, Zhang\u00a0L, McCrae\u00a0KR (2013) Management and outcomes for patients with TTP: analysis of 100 cases at a\u00a0single institution. Am J Hematol 88(7):560\u2013565. https:\/\/doi.org\/10.1002\/ajh.23455","journal-title":"Am J Hematol"},{"issue":"4","key":"1835_CR63","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1111\/j.1538-7836.2009.03285.x","volume":"7","author":"C Hughes","year":"2009","unstructured":"Hughes\u00a0C, McEwan\u00a0JR, Longair\u00a0I, Hughes\u00a0S, Cohen\u00a0H, Machin\u00a0S, Scully\u00a0M (2009) Cardiac involvement in acute thrombotic thrombocytopenic purpura: association with troponin T and IgG antibodies to ADAMTS 13. J\u00a0Thromb Haemost 7(4):529\u2013536. https:\/\/doi.org\/10.1111\/j.1538-7836.2009.03285.x","journal-title":"J Thromb Haemost"},{"issue":"7","key":"1835_CR64","doi-asserted-by":"publisher","first-page":"e24547","DOI":"10.1002\/jcla.24547","volume":"36","author":"Y Xu","year":"2022","unstructured":"Xu\u00a0Y, Gu\u00a0C, Wang\u00a0R, Qi\u00a0J, Wang\u00a0J, Jiang\u00a0T, Jiang\u00a0M, Wu\u00a0D, You\u00a0T, Fu\u00a0J (2022) Prognostic value of dynamic cardiac biomarkers in patients with acquired refractory thrombocytopenic purpura: A\u00a0retrospective study in Chinese population. J\u00a0Clin Lab Anal 36(7):e24547. https:\/\/doi.org\/10.1002\/jcla.24547","journal-title":"J Clin Lab Anal"},{"key":"1835_CR65","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2024.05.016","author":"M Urra","year":"2024","unstructured":"Urra\u00a0M, Lyons\u00a0S, Teodosiu\u00a0CG, Burwick\u00a0R, Java\u00a0A (2024) Thrombotic Microangiopathy in Pregnancy: Current Understanding and Management Strategies. Kidney Int Rep. https:\/\/doi.org\/10.1016\/j.ekir.2024.05.016","journal-title":"Kidney Int Rep"},{"issue":"24","key":"1835_CR66","doi-asserted-by":"publisher","first-page":"5888","DOI":"10.1182\/blood-2012-02-408914","volume":"119","author":"M Moatti-Cohen","year":"2012","unstructured":"Moatti-Cohen\u00a0M, Garrec\u00a0C, Wolf\u00a0M, Boisseau\u00a0P, Galicier\u00a0L, Azoulay\u00a0E, Stepanian\u00a0A, Delmas\u00a0Y, Rondeau\u00a0E, Bezieau\u00a0S, Coppo\u00a0P, Veyradier\u00a0A, French Reference Center for Thrombotic M (2012) Unexpected frequency of Upshaw-Schulman syndrome in pregnancy-onset thrombotic thrombocytopenic purpura. Blood 119(24):5888\u20135897. https:\/\/doi.org\/10.1182\/blood-2012-02-408914","journal-title":"Blood"},{"issue":"11","key":"1835_CR67","doi-asserted-by":"publisher","first-page":"e112935","DOI":"10.1371\/journal.pone.0112935","volume":"9","author":"DN Drury-Stewart","year":"2014","unstructured":"Drury-Stewart\u00a0DN, Lannert\u00a0KW, Chung\u00a0DW, Teramura\u00a0GT, Zimring\u00a0JC, Konkle\u00a0BA, Gammill\u00a0HS, Johnsen\u00a0JM (2014) Complex changes in von Willebrand factor-associated parameters are acquired during uncomplicated pregnancy. Plos One 9(11):e112935. https:\/\/doi.org\/10.1371\/journal.pone.0112935","journal-title":"Plos One"},{"issue":"6","key":"1835_CR68","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.1160\/TH03-11-0683","volume":"92","author":"A Sanchez-Luceros","year":"2004","unstructured":"Sanchez-Luceros\u00a0A, Farias\u00a0CE, Amaral\u00a0MM, Kempfer\u00a0AC, Votta\u00a0R, Marchese\u00a0C, Salviu\u00a0MJ, Woods\u00a0AI, Meschengieser\u00a0SS, Lazzari\u00a0MA (2004) von Willebrand factor-cleaving protease (ADAMTS13) activity in normal non-pregnant women, pregnant and post-delivery women. Thromb Haemost 92(6):1320\u20131326. https:\/\/doi.org\/10.1160\/TH03-11-0683","journal-title":"Thromb Haemost"},{"issue":"1","key":"1835_CR69","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1111\/jth.15561","volume":"20","author":"M Lavin","year":"2022","unstructured":"Lavin\u00a0M, Sanchez Luceros\u00a0A, Kouides\u00a0P, Abdul-Kadir\u00a0R, O\u2019Donnell\u00a0JS, Baker\u00a0RI, Othman\u00a0M, Haberichter\u00a0SL, Factor\u00a0IVW, Factor\u00a0IVW, Women\u2019s Health Scientific S (2022) Examining international practices in the management of pregnant women with von Willebrand disease. J\u00a0Thromb Haemost 20(1):82\u201391. https:\/\/doi.org\/10.1111\/jth.15561","journal-title":"J Thromb Haemost"},{"key":"1835_CR70","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25042163","author":"A Mititelu","year":"2024","unstructured":"Mititelu\u00a0A, Onisai\u00a0MC, Rosca\u00a0A, Vladareanu\u00a0AM (2024) Current Understanding of Immune Thrombocytopenia: A\u00a0Review of Pathogenesis and Treatment Options. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms25042163","journal-title":"Int J Mol Sci"},{"issue":"3","key":"1835_CR71","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1055\/s-0039-1697930","volume":"46","author":"E Danese","year":"2020","unstructured":"Danese\u00a0E, Montagnana\u00a0M, Favaloro\u00a0EJ, Lippi\u00a0G (2020) Drug-Induced Thrombocytopenia: Mechanisms and Laboratory Diagnostics. Semin Thromb Hemost 46(3):264\u2013274. https:\/\/doi.org\/10.1055\/s-0039-1697930","journal-title":"Semin Thromb Hemost"},{"issue":"7","key":"1835_CR72","doi-asserted-by":"publisher","first-page":"e023397","DOI":"10.1161\/JAHA.121.023397","volume":"11","author":"R Boulestreau","year":"2022","unstructured":"Boulestreau\u00a0R, van den Born\u00a0BH, Lip\u00a0GYH, Gupta\u00a0A (2022) Malignant Hypertension: Current Perspectives and Challenges. J\u00a0Am Heart Assoc 11(7):e23397. https:\/\/doi.org\/10.1161\/JAHA.121.023397","journal-title":"J Am Heart Assoc"},{"issue":"5","key":"1835_CR73","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1093\/ndt\/gfac248","volume":"38","author":"T Cavero","year":"2023","unstructured":"Cavero\u00a0T, Aunon\u00a0P, Caravaca-Fontan\u00a0F, Trujillo\u00a0H, Arjona\u00a0E, Morales\u00a0E, Guillen\u00a0E, Blasco\u00a0M, Rabasco\u00a0C, Espinosa\u00a0M, Blanco\u00a0M, Rodriguez-Magarinos\u00a0C, Cao\u00a0M, Avila\u00a0A, Huerta\u00a0A, Rubio\u00a0E, Cabello\u00a0V, Barros\u00a0X, Goicoechea de Jorge\u00a0E, Rodriguez de Cordoba\u00a0S, Praga\u00a0M (2023) Thrombotic microangiopathy in patients with malignant hypertension. Nephrol Dial Transplant 38(5):1217\u20131226. https:\/\/doi.org\/10.1093\/ndt\/gfac248","journal-title":"Nephrol Dial Transplant"},{"issue":"4","key":"1835_CR74","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1016\/j.kint.2019.05.014","volume":"96","author":"T Cavero","year":"2019","unstructured":"Cavero\u00a0T, Arjona\u00a0E, Soto\u00a0K, Caravaca-Fontan\u00a0F, Rabasco\u00a0C, Bravo\u00a0L, de la Cerda\u00a0F, Martin\u00a0N, Blasco\u00a0M, Avila\u00a0A, Huerta\u00a0A, Cabello\u00a0V, Jarque\u00a0A, Alcazar\u00a0C, Fulladosa\u00a0X, Carbayo\u00a0J, Anaya\u00a0S, Cobelo\u00a0C, Ramos\u00a0N, Iglesias\u00a0E, Baltar\u00a0J, Martinez-Gallardo\u00a0R, Perez\u00a0L, Morales\u00a0E, Gonzalez\u00a0R, Macia\u00a0M, Draibe\u00a0J, Pallardo\u00a0L, Quintana\u00a0LF, Espinosa\u00a0M, Barros\u00a0X, Pereira\u00a0F, Cao\u00a0M, Moreno\u00a0JA, Rodriguez de Cordoba\u00a0S, Praga\u00a0M, Spanish Group for the Study of Glomerular D (2019) Severe and malignant hypertension are common in primary atypical hemolytic uremic syndrome. Kidney Int 96(4):995\u20131004. https:\/\/doi.org\/10.1016\/j.kint.2019.05.014","journal-title":"Kidney Int"},{"issue":"1","key":"1835_CR75","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41371-019-0267-y","volume":"34","author":"M Domek","year":"2020","unstructured":"Domek\u00a0M, Gumprecht\u00a0J, Lip\u00a0GYH, Shantsila\u00a0A (2020) Malignant hypertension: does this still exist? J\u00a0Hum Hypertens 34(1):1\u20134. https:\/\/doi.org\/10.1038\/s41371-019-0267-y","journal-title":"J Hum Hypertens"},{"issue":"14","key":"1835_CR76","doi-asserted-by":"publisher","first-page":"2849","DOI":"10.1111\/bph.15171","volume":"178","author":"UO Wenzel","year":"2021","unstructured":"Wenzel\u00a0UO, Kemper\u00a0C, Bode\u00a0M (2021) The role of complement in arterial hypertension and hypertensive end organ damage. Br J Pharmacol 178(14):2849\u20132862. https:\/\/doi.org\/10.1111\/bph.15171","journal-title":"Br J Pharmacol"},{"issue":"10","key":"1835_CR77","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1038\/s41371-022-00776-9","volume":"37","author":"S Kulkarni","year":"2023","unstructured":"Kulkarni\u00a0S, Glover\u00a0M, Kapil\u00a0V, Abrams\u00a0SML, Partridge\u00a0S, McCormack\u00a0T, Sever\u00a0P, Delles\u00a0C, Wilkinson\u00a0IB (2023) Management of hypertensive crisis: British and Irish Hypertension Society Position document. J\u00a0Hum Hypertens 37(10):863\u2013879. https:\/\/doi.org\/10.1038\/s41371-022-00776-9","journal-title":"J Hum Hypertens"},{"key":"1835_CR78","doi-asserted-by":"publisher","first-page":"7306070","DOI":"10.1155\/2022\/7306070","volume":"2022","author":"D Morrissey","year":"2022","unstructured":"Morrissey\u00a0D, Sun\u00a0Y, Koilpillai\u00a0S, Kropf\u00a0J, Carlan\u00a0SJ (2022) Pseudo-Thrombotic Microangiopathy Secondary to Vitamin\u00a0B12 Deficiency. Case Rep Med 2022:7306070. https:\/\/doi.org\/10.1155\/2022\/7306070","journal-title":"Case Rep Med"},{"issue":"4","key":"1835_CR79","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1093\/ckj\/sfaa195","volume":"14","author":"M Blasco","year":"2021","unstructured":"Blasco\u00a0M, Guillen\u00a0E, Quintana\u00a0LF, Garcia-Herrera\u00a0A, Pineiro\u00a0G, Poch\u00a0E, Carreras\u00a0E, Campistol\u00a0JM, Diaz-Ricart\u00a0M, Palomo\u00a0M (2021) Thrombotic microangiopathies assessment: mind the complement. Clin Kidney\u00a0J 14(4):1055\u20131066. https:\/\/doi.org\/10.1093\/ckj\/sfaa195","journal-title":"Clin Kidney J"},{"issue":"9","key":"1835_CR80","doi-asserted-by":"publisher","first-page":"1189","DOI":"10.1016\/j.mayocp.2016.05.015","volume":"91","author":"RS Go","year":"2016","unstructured":"Go\u00a0RS, Winters\u00a0JL, Leung\u00a0N, Murray\u00a0DL, Willrich\u00a0MA, Abraham\u00a0RS, Amer\u00a0H, Hogan\u00a0WJ, Marshall\u00a0AL, Sethi\u00a0S, Tran\u00a0CL, Chen\u00a0D, Pruthi\u00a0RK, Ashrani\u00a0AA, Fervenza\u00a0FC, Cramer\u00a0CH 2nd, Rodriguez\u00a0V, Wolanskyj\u00a0AP, Thome\u00a0SD, Hook\u00a0CC, Mayo Clinic Complement Alternative Pathway-Thrombotic Microangiopathy Disease-Oriented G (2016) Thrombotic Microangiopathy Care Pathway: A\u00a0Consensus Statement for the Mayo Clinic Complement Alternative Pathway-Thrombotic Microangiopathy (CAP-TMA) Disease-Oriented Group. Mayo Clin Proc 91(9):1189\u20131211. https:\/\/doi.org\/10.1016\/j.mayocp.2016.05.015","journal-title":"Mayo Clin Proc"}],"container-title":["Die Innere Medizin"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-024-01835-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00108-024-01835-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-024-01835-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,15]],"date-time":"2025-02-15T00:35:55Z","timestamp":1739579755000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00108-024-01835-8"}},"subtitle":["Detaillierter Blick auf thrombotische Mikroangiopathien","Detailed view at thrombotic microangiopathies"],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":80,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["1835"],"URL":"https:\/\/doi.org\/10.1007\/s00108-024-01835-8","relation":{},"ISSN":["2731-7080","2731-7099"],"issn-type":[{"value":"2731-7080","type":"print"},{"value":"2731-7099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"10 December 2024","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 January 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 February 2025","order":3,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":4,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Im englischen Abstract war das Wort \u201ethrombopenia\u201c falsch geschrieben.","order":5,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"Gem\u00e4\u00df den Richtlinien des Springer Medizin Verlags werden Autoren und Wissenschaftliche Leitung im Rahmen der Manuskripterstellung und Manuskriptfreigabe aufgefordert, eine vollst\u00e4ndige Erkl\u00e4rung zu ihren finanziellen und nichtfinanziellen Interessen abzugeben.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"S. A. Potthoff: A. Finanzielle Interessen: Referent: Sanofi-Aventis Deutschland GmbH, Alexion Pharma Germany GmbH. \u2013 Beratung: Sanofi-Aventis Deutschland GmbH, Beratung, Interne Schulung: Alexion Pharma Germany GmbH. \u2013 B. Nichtfinanzielle Interessen: Mitgliedschaft: DGIM.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Autoren"}},{"value":"Die vollst\u00e4ndige Erkl\u00e4rung zum Interessenkonflikt der Wissenschaftlichen Leitung finden Sie am Kurs der zertifizierten Fortbildung auf .","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Wissenschaftliche Leitung"}},{"value":"erkl\u00e4rt, dass f\u00fcr die Publikation dieser CME-Fortbildung keine Sponsorengelder an den Verlag flie\u00dfen.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}},{"value":"F\u00fcr diesen Beitrag wurden vom Autor keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Der Verlag"}}]}}