{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:16:51Z","timestamp":1782209811693,"version":"3.54.5"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"},{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"}],"funder":[{"name":"Universit\u00e4tsklinikum Leipzig"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Innere Medizin"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n          <jats:p>Wir berichten \u00fcber zwei Patienten, die im Jahr 2023 mit pulmonalen Herdbefunden und mediastinaler\nLymphknotenschwellung im Universit\u00e4tsklinikum Leipzig behandelt wurden. Histologisch zeigte sich in beiden F\u00e4llen eine granulomat\u00f6se Entz\u00fcndungsreaktion. Als Ursache der Erkrankung konnte eine Infektion mit <jats:italic>Francisella tularensis<\/jats:italic> nachgewiesen werden. F\u00fcr beide Patienten bestand die mutma\u00dfliche Infektionsquelle in der freizeitlichen Besch\u00e4ftigung mit der Jagd, die eines der Risiken f\u00fcr eine Infektion darstellt. Unter antibiotischer Therapie boten beide F\u00e4lle einen unkomplizierten Verlauf.<\/jats:p>","DOI":"10.1007\/s00108-025-01895-4","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T04:43:33Z","timestamp":1746420213000},"page":"863-867","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Unklare Rundherde und Lymphadenopathie\u00a0\u2013 die Spur f\u00fchrt zur Natur","Indeterminate pulmonary lesions and lymphadenopathy: A trail leading to nature"],"prefix":"10.1007","volume":"66","author":[{"given":"Philipp","family":"Gessner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximillian","family":"Von Laffert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Ullrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert","family":"Wirtz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-J\u00fcrgen","family":"Seyfarth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,5]]},"reference":[{"issue":"3\u20134","key":"1895_CR1","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.vetmic.2009.07.017","volume":"140","author":"JE Foley","year":"2010","unstructured":"Foley\u00a0JE, Nieto\u00a0NC (2010) Tularemia. 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Open Forum Infect Dis 11(2):ofad636","journal-title":"Open Forum Infect Dis"},{"issue":"2","key":"1895_CR7","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1007\/s00292-013-1851-5","volume":"35","author":"J Strehl","year":"2014","unstructured":"Strehl\u00a0J, Schoerner\u00a0C, Hartmann\u00a0A, Agaimy\u00a0A (2014) Tular\u00e4mie-Lymphadenitis. Eine wichtige Differenzialdiagnose granulomat\u00f6s-nekrotisierender zervikaler Lymphadenitiden. Pathologe 35(2):166\u2013172","journal-title":"Pathologe"},{"key":"1895_CR8","volume-title":"Hinweise zur Therapie der Tular\u00e4mie","author":"St\u00e4ndiger Arbeitskreis der Kompetenz- und Behandlungszentren f\u00fcr Krankheiten durch hochpathogene Erreger","year":"2021","unstructured":"St\u00e4ndiger Arbeitskreis der Kompetenz- und Behandlungszentren f\u00fcr Krankheiten durch hochpathogene Erreger (2021) Hinweise zur Therapie der Tular\u00e4mie"},{"key":"1895_CR9","doi-asserted-by":"publisher","first-page":"40","DOI":"10.3389\/fcimb.2014.00040","volume":"4","author":"S Boisset","year":"2014","unstructured":"Boisset\u00a0S, Caspar\u00a0Y, Sutera\u00a0V, Maurin\u00a0M (2014) New therapeutic approaches for treatment of tularaemia: a\u00a0review. Front Cell Infect Microbiol 4:40","journal-title":"Front Cell Infect Microbiol"},{"issue":"9","key":"1895_CR10","doi-asserted-by":"publisher","first-page":"ofy176","DOI":"10.1093\/ofid\/ofy176","volume":"5","author":"C Rojas-Moreno","year":"2018","unstructured":"Rojas-Moreno\u00a0C, Bhartee\u00a0H, Vasudevan\u00a0A, Adiga\u00a0R, Salzer\u00a0W (2018) Tetracyclines for Treatment of Tularemia: A\u00a0Case Series. Open Forum Infect Dis 5(9):ofy176","journal-title":"Open Forum Infect Dis"},{"issue":"2","key":"1895_CR11","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1183\/09031936.03.00088903","volume":"21","author":"A T\u00e4rnvik","year":"2003","unstructured":"T\u00e4rnvik\u00a0A, Berglund\u00a0L (2003) Tularaemia. Eur Respir\u00a0J 21(2):361\u2013373","journal-title":"Eur Respir J"}],"container-title":["Die Innere Medizin"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-025-01895-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00108-025-01895-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00108-025-01895-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T13:09:53Z","timestamp":1757164193000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00108-025-01895-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,5]]},"references-count":11,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["1895"],"URL":"https:\/\/doi.org\/10.1007\/s00108-025-01895-4","relation":{},"ISSN":["2731-7080","2731-7099"],"issn-type":[{"value":"2731-7080","type":"print"},{"value":"2731-7099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,5]]},"assertion":[{"value":"17 March 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 May 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"P.\u00a0Gessner, M.\u00a0Von Laffert, S.\u00a0Ullrich, H.\u00a0Wirtz und H.-J.\u00a0Seyfarth geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. F\u00fcr Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, \u00fcber die Patient\/-innen zu identifizieren sind, liegt von ihnen und\/oder ihren gesetzlichen Vertretern\/Vertreterinnen eine schriftliche Einwilligung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}