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Beide Erkrankungen werden durch eine hohe Natriumaufnahme \u00fcber Speisesalz und verarbeitete Lebensmittel beg\u00fcnstigt. Kalium wirkt hingegen blutdrucksenkend und k\u00f6nnte daher als Ersatz f\u00fcr Natrium in Speisesalzen verwendet werden, um dessen negativen Einfluss auf Hypertonie und Herzinsuffizienz zu reduzieren.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ziel der \u00dcbersicht<\/jats:title>\n                    <jats:p>In der vorliegenden \u00dcbersicht soll die aktuelle Evidenz zu den kardiovaskul\u00e4ren Effekten von natrium- und kaliumhaltigen Speisesalzen zusammengefasst werden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Datenlage<\/jats:title>\n                    <jats:p>Epidemiologische Studien zeigen konsistent, dass eine hohe Natriumaufnahme mit erh\u00f6htem Blutdruck und einer h\u00f6heren Rate kardiovaskul\u00e4rer Ereignisse assoziiert ist. Metaanalysen belegen zudem, dass eine Reduktion des Natriumkonsums zu einer Abnahme kardiovaskul\u00e4rer Ereignisse beitr\u00e4gt. In einer clusterrandomisierten Studie f\u00fchrte der teilweise Ersatz von natrium- durch kaliumhaltige Speisesalze bei arterieller Hypertonie zu einer Reduktion kardiovaskul\u00e4rer Ereignisse und kardiovaskul\u00e4rer Sterblichkeit. Robuste Daten zur Reduktion harter klinischer Endpunkte durch Natriumreduktion bei Herzinsuffizienz gibt es gegenw\u00e4rtig nicht.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Schlussfolgerung<\/jats:title>\n                    <jats:p>Eine hohe Natriumaufnahme hat nachweislich negative Effekte auf die kardiovaskul\u00e4re Gesundheit. Der Ersatz von natrium- durch kaliumhaltige Speisesalze stellt daher einen vielversprechenden Ansatz dar, um die hohe Morbidit\u00e4t und Mortalit\u00e4t von Bluthochdruck zu mindern.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00108-026-02112-6","type":"journal-article","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T07:41:35Z","timestamp":1777966895000},"page":"935-941","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Kaliumsubstitution \u2013 ist der Ersatz von natrium- durch kaliumhaltige Speisesalze sinnvoll?","Potassium substitution: is replacing sodium with potassium-enriched salts beneficial?"],"prefix":"10.1007","volume":"67","author":[{"given":"Felix","family":"G\u00f6tzinger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Kunz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Lauder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Mahfoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,5]]},"reference":[{"key":"2112_CR1","doi-asserted-by":"publisher","first-page":"f1378","DOI":"10.1136\/bmj.f1378","volume":"346","author":"NJ Aburto","year":"2013","unstructured":"Aburto\u00a0NJ, Hanson\u00a0S, Gutierrez\u00a0H et\u00a0al (2013) Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses. 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Er erhielt Reiseunterst\u00fctzung von Boehringer Ingelheim. Aktuell wird er von der Universit\u00e4t Basel im Rahmen des \u201eJunior Excellence Fonds\u201c unterst\u00fctzt. F.\u00a0G\u00f6tzinger ist ein Berater von Alpalix GmbH. M.\u00a0Kunz hat Honorare von Merck erhalten. M.\u00a0Kunz ist ein Berater von Alpalix GmbH. L.\u00a0Lauder hat Beratungshonorare von Medtronic, Recor und Biosensors erhalten sowie Vortragshonorare von AstraZeneca, Medtronic, Pfizer, Recor, Sanofi und Servier; diese wurden alle an seine Institution gezahlt. F.\u00a0Mahfoud wurde von der Deutschen Forschungsgemeinschaft (SFB TRR219, Project-ID 322900939) und der Deutschen Herzstiftung unterst\u00fctzt. Seine ehemalige Institution, die Universit\u00e4t des Saarlandes, hat wissenschaftliche Unterst\u00fctzung von Ablative Solutions, Medtronic und Recor Medical erhalten. Bis Mai 2024 hat F.\u00a0Mahfoud Vortrags- und Beraterhonorare von Ablative Solutions, AstraZeneca, Inari, Medtronic, Merck, Novartis, Philips und Recor erhalten.","order":1,"name":"Ethics","label":"Interessenkonflikt","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}}]}}