{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T22:39:07Z","timestamp":1776206347396,"version":"3.50.1"},"reference-count":61,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2015,2,18]],"date-time":"2015-02-18T00:00:00Z","timestamp":1424217600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Dutch government","award":["s\/000083\/01\/AN"],"award-info":[{"award-number":["s\/000083\/01\/AN"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Mol Med"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1007\/s00109-015-1259-1","type":"journal-article","created":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T19:05:19Z","timestamp":1478027119000},"page":"395-402","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Complement evasion by Bordetella pertussis: implications for improving current vaccines"],"prefix":"10.1007","volume":"93","author":[{"given":"Ilse","family":"Jongerius","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim J.","family":"Schuijt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frits R.","family":"Mooi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Pinelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,2,18]]},"reference":[{"issue":"6","key":"1259_CR1","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1093\/infdis\/jis443","volume":"206","author":"JM Warfel","year":"2012","unstructured":"Warfel JM, Beren J, Merkel TJ (2012) Airborne transmission of Bordetella pertussis. J Infect Dis 206(6):902\u2013906","journal-title":"J Infect Dis"},{"issue":"2","key":"1259_CR2","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1128\/CMR.18.2.326-382.2005","volume":"18","author":"S Mattoo","year":"2005","unstructured":"Mattoo S, Cherry JD (2005) Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies. Clin Microbiol Rev 18(2):326\u2013382","journal-title":"Clin Microbiol Rev"},{"key":"1259_CR3","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1146\/annurev.mi.40.100186.003305","volume":"40","author":"AA Weiss","year":"1986","unstructured":"Weiss AA, Hewlett EL (1986) Virulence factors of Bordetella pertussis. Annu Rev Microbiol 40:661\u2013686","journal-title":"Annu Rev Microbiol"},{"issue":"3","key":"1259_CR4","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1086\/589753","volume":"47","author":"CD Paddock","year":"2008","unstructured":"Paddock CD, Sanden GN, Cherry JD, Gal AA, Langston C, Tatti KM, Wu KH, Goldsmith CS, Greer PW, Montague JL et al (2008) Pathology and pathogenesis of fatal Bordetella pertussis infection in infants. Clin Infect Dis Off Publ Infec Dis Soc Am 47(3):328\u2013338","journal-title":"Clin Infect Dis Off Publ Infec Dis Soc Am"},{"issue":"7","key":"1259_CR5","doi-asserted-by":"publisher","first-page":"e1003418","DOI":"10.1371\/journal.ppat.1003418","volume":"9","author":"JD Cherry","year":"2013","unstructured":"Cherry JD (2013) Pertussis: challenges today and for the future. PLoS Pathog 9(7):e1003418","journal-title":"PLoS Pathog"},{"key":"1259_CR6","unstructured":"Mooi FR, NA VDM, De Melker HE (2013) Pertussis resurgence: waning immunity and pathogen adaptation\u2014two sides of the same coin. Epidemiol Infect 142(4):685\u2013694"},{"issue":"9","key":"1259_CR7","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1586\/erv.12.83","volume":"11","author":"AA Ark van der","year":"2012","unstructured":"van der Ark AA, Hozbor DF, Boog CJ, Metz B, van den Dobbelsteen GP, van Els CA (2012) Resurgence of pertussis calls for re-evaluation of pertussis animal models. Expert Rev Vaccines 11(9):1121\u20131137","journal-title":"Expert Rev Vaccines"},{"issue":"3","key":"1259_CR8","doi-asserted-by":"publisher","first-page":"329","DOI":"10.2217\/17460913.3.3.329","volume":"3","author":"Q He","year":"2008","unstructured":"He Q, Mertsola J (2008) Factors contributing to pertussis resurgence. Future Microbiol 3(3):329\u2013339","journal-title":"Future Microbiol"},{"issue":"9","key":"1259_CR9","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1056\/NEJMp1209051","volume":"367","author":"JD Cherry","year":"2012","unstructured":"Cherry JD (2012) Epidemic pertussis in 2012\u2014the resurgence of a vaccine-preventable disease. N Engl J Med 367(9):785\u2013787","journal-title":"N Engl J Med"},{"issue":"3","key":"1259_CR10","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.molimm.2013.05.222","volume":"56","author":"PF Zipfel","year":"2013","unstructured":"Zipfel PF, Hallstrom T, Riesbeck K (2013) Human complement control and complement evasion by pathogenic microbes\u2014tipping the balance. Mol Immunol 56(3):152\u2013160","journal-title":"Mol Immunol"},{"issue":"15","key":"1259_CR11","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1056\/NEJM200104123441506","volume":"344","author":"MJ Walport","year":"2001","unstructured":"Walport MJ (2001) Complement. Second of two parts. N Engl J Med 344(15):1140\u20131144","journal-title":"N Engl J Med"},{"issue":"14","key":"1259_CR12","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1056\/NEJM200104053441406","volume":"344","author":"MJ Walport","year":"2001","unstructured":"Walport MJ (2001) Complement. First of two parts. N Engl J Med 344(14):1058\u20131066","journal-title":"N Engl J Med"},{"key":"1259_CR13","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1146\/annurev.iy.04.040186.002443","volume":"4","author":"HJ Muller-Eberhard","year":"1986","unstructured":"Muller-Eberhard HJ (1986) The membrane attack complex of complement. Annu Rev Immunol 4:503\u2013528","journal-title":"Annu Rev Immunol"},{"issue":"9","key":"1259_CR14","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1038\/ni.1923","volume":"11","author":"D Ricklin","year":"2010","unstructured":"Ricklin D, Hajishengallis G, Yang K, Lambris JD (2010) Complement: a key system for immune surveillance and homeostasis. Nat Immunol 11(9):785\u2013797","journal-title":"Nat Immunol"},{"issue":"12","key":"1259_CR15","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1038\/nri3761","volume":"14","author":"M Kolev","year":"2014","unstructured":"Kolev M, Le Friec G, Kemper C (2014) Complement\u2014tapping into new sites and effector systems. Nat Rev Immunol 14(12):811\u2013820","journal-title":"Nat Rev Immunol"},{"issue":"5 Pt 1","key":"1259_CR16","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1164\/ajrccm\/143.5_Pt_1.1062","volume":"143","author":"AB Bjornson","year":"1991","unstructured":"Bjornson AB, Mellencamp MA, Schiff GM (1991) Complement is activated in the upper respiratory tract during influenza virus infection. Am Rev Respir Dis 143(5 Pt 1):1062\u20131066","journal-title":"Am Rev Respir Dis"},{"issue":"1","key":"1259_CR17","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1111\/j.1365-2222.1991.tb00799.x","volume":"21","author":"CG Persson","year":"1991","unstructured":"Persson CG, Erjefalt I, Alkner U, Baumgarten C, Greiff L, Gustafsson B, Luts A, Pipkorn U, Sundler F, Svensson C et al (1991) Plasma exudation as a first line respiratory mucosal defence. Clin Exp Allergy J Br Soc Allergy Clin Immunol 21(1):17\u201324","journal-title":"Clin Exp Allergy J Br Soc Allergy Clin Immunol"},{"issue":"5","key":"1259_CR18","doi-asserted-by":"crossref","first-page":"L790","DOI":"10.1152\/ajplung.2000.279.5.L790","volume":"279","author":"WT Watford","year":"2000","unstructured":"Watford WT, Ghio AJ, Wright JR (2000) Complement-mediated host defense in the lung. Am J Physiol Lung Cell Mol Physiol 279(5):L790\u2013L798","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"2","key":"1259_CR19","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.immuni.2012.08.002","volume":"37","author":"MC Carroll","year":"2012","unstructured":"Carroll MC, Isenman DE (2012) Regulation of humoral immunity by complement. Immunity 37(2):199\u2013207","journal-title":"Immunity"},{"issue":"3","key":"1259_CR20","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.molimm.2013.05.223","volume":"56","author":"C Kemper","year":"2013","unstructured":"Kemper C, Kohl J (2013) Novel roles for complement receptors in T cell regulation and beyond. Mol Immunol 56(3):181\u2013190","journal-title":"Mol Immunol"},{"issue":"1","key":"1259_CR21","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1038\/nri1994","volume":"7","author":"C Kemper","year":"2007","unstructured":"Kemper C, Atkinson JP (2007) T-cell regulation: with complements from innate immunity. Nat Rev Immunol 7(1):9\u201318","journal-title":"Nat Rev Immunol"},{"issue":"2","key":"1259_CR22","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.imbio.2011.07.016","volume":"217","author":"W Zhou","year":"2012","unstructured":"Zhou W (2012) The new face of anaphylatoxins in immune regulation. Immunobiology 217(2):225\u2013234","journal-title":"Immunobiology"},{"issue":"1","key":"1259_CR23","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.smim.2013.04.012","volume":"25","author":"M Kolev","year":"2013","unstructured":"Kolev M, Le Friec G, Kemper C (2013) The role of complement in CD4(+) T cell homeostasis and effector functions. Semin Immunol 25(1):12\u201319","journal-title":"Semin Immunol"},{"issue":"5","key":"1259_CR24","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1182\/blood-2009-01-198283","volume":"114","author":"C Fang","year":"2009","unstructured":"Fang C, Zhang X, Miwa T, Song WC (2009) Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production. Blood 114(5):1005\u20131015","journal-title":"Blood"},{"issue":"5","key":"1259_CR25","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/mi.2012.54","volume":"5","author":"R Higgs","year":"2012","unstructured":"Higgs R, Higgins SC, Ross PJ, Mills KH (2012) Immunity to the respiratory pathogen Bordetella pertussis. Mucosal Immunol 5(5):485\u2013500","journal-title":"Mucosal Immunol"},{"issue":"4","key":"1259_CR26","doi-asserted-by":"publisher","first-page":"1774","DOI":"10.1128\/IAI.01629-07","volume":"76","author":"EM Goebel","year":"2008","unstructured":"Goebel EM, Wolfe DN, Elder K, Stibitz S, Harvill ET (2008) O antigen protects Bordetella parapertussis from complement. Infect Immun 76(4):1774\u20131780","journal-title":"Infect Immun"},{"issue":"1","key":"1259_CR27","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1128\/IAI.71.1.86-94.2003","volume":"71","author":"VC Burns","year":"2003","unstructured":"Burns VC, Pishko EJ, Preston A, Maskell DJ, Harvill ET (2003) Role of Bordetella O antigen in respiratory tract infection. Infect Immun 71(1):86\u201394","journal-title":"Infect Immun"},{"issue":"Suppl 8","key":"1259_CR28","doi-asserted-by":"publisher","first-page":"I34","DOI":"10.1016\/j.vaccine.2008.11.059","volume":"26","author":"E Kugelberg","year":"2008","unstructured":"Kugelberg E, Gollan B, Tang CM (2008) Mechanisms in Neisseria meningitidis for resistance against complement-mediated killing. Vaccine 26(Suppl 8):I34\u2013I39","journal-title":"Vaccine"},{"issue":"7470","key":"1259_CR29","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1038\/nature12616","volume":"502","author":"E Loh","year":"2013","unstructured":"Loh E, Kugelberg E, Tracy A, Zhang Q, Gollan B, Ewles H, Chalmers R, Pelicic V, Tang CM (2013) Temperature triggers immune evasion by Neisseria meningitidis. Nature 502(7470):237\u2013240","journal-title":"Nature"},{"issue":"6","key":"1259_CR30","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1111\/j.1365-2958.2010.07297.x","volume":"77","author":"MS Conover","year":"2010","unstructured":"Conover MS, Sloan GP, Love CF, Sukumar N, Deora R (2010) The Bps polysaccharide of Bordetella pertussis promotes colonization and biofilm formation in the nose by functioning as an adhesin. Mol Microbiol 77(6):1439\u20131455","journal-title":"Mol Microbiol"},{"key":"1259_CR31","doi-asserted-by":"crossref","unstructured":"Geurtsen J, Fae KC, van den Dobbelsteen GP (2014) Importance of (antibody-dependent) complement-mediated serum killing in protection against Bordetella pertussis. Expert Rev Vaccines 13(10):1229\u20131240","DOI":"10.1586\/14760584.2014.944901"},{"issue":"7","key":"1259_CR32","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1111\/cmi.12264","volume":"16","author":"T Ganguly","year":"2014","unstructured":"Ganguly T, Johnson JB, Kock ND, Parks GD, Deora R (2014) The Bordetella pertussis Bps polysaccharide enhances lung colonization by conferring protection from complement-mediated killing. Cell Microbiol 16(7):1105\u20131118","journal-title":"Cell Microbiol"},{"issue":"11","key":"1259_CR33","doi-asserted-by":"crossref","first-page":"4727","DOI":"10.1128\/IAI.62.11.4727-4738.1994","volume":"62","author":"RC Fernandez","year":"1994","unstructured":"Fernandez RC, Weiss AA (1994) Cloning and sequencing of a Bordetella pertussis serum resistance locus. Infect Immun 62(11):4727\u20134738","journal-title":"Infect Immun"},{"issue":"5","key":"1259_CR34","doi-asserted-by":"publisher","first-page":"3067","DOI":"10.1128\/IAI.69.5.3067-3072.2001","volume":"69","author":"MG Barnes","year":"2001","unstructured":"Barnes MG, Weiss AA (2001) BrkA protein of Bordetella pertussis inhibits the classical pathway of complement after C1 deposition. Infect Immun 69(5):3067\u20133072","journal-title":"Infect Immun"},{"issue":"3","key":"1259_CR35","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.micpath.2011.04.004","volume":"51","author":"M Noofeli","year":"2011","unstructured":"Noofeli M, Bokhari H, Blackburn P, Roberts M, Coote JG, Parton R (2011) BapC autotransporter protein is a virulence determinant of Bordetella pertussis. Microb Pathog 51(3):169\u2013177","journal-title":"Microb Pathog"},{"issue":"4","key":"1259_CR36","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1055\/s-0031-1276585","volume":"37","author":"S Zeerleder","year":"2011","unstructured":"Zeerleder S (2011) C1-inhibitor: more than a serine protease inhibitor. Semin Thromb Hemost 37(4):362\u2013374","journal-title":"Semin Thromb Hemost"},{"issue":"4","key":"1259_CR37","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1086\/510913","volume":"195","author":"N Marr","year":"2007","unstructured":"Marr N, Luu RA, Fernandez RC (2007) Bordetella pertussis binds human C1 esterase inhibitor during the virulent phase, to evade complement-mediated killing. J Infect Dis 195(4):585\u2013588","journal-title":"J Infect Dis"},{"issue":"17","key":"1259_CR38","doi-asserted-by":"publisher","first-page":"6671","DOI":"10.1073\/pnas.86.17.6671","volume":"86","author":"B Arico","year":"1989","unstructured":"Arico B, Miller JF, Roy C, Stibitz S, Monack D, Falkow S, Gross R, Rappuoli R (1989) Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transduction proteins. Proc Natl Acad Sci U S A 86(17):6671\u20136675","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6","key":"1259_CR39","doi-asserted-by":"publisher","first-page":"e20585","DOI":"10.1371\/journal.pone.0020585","volume":"6","author":"N Marr","year":"2011","unstructured":"Marr N, Shah NR, Lee R, Kim EJ, Fernandez RC (2011) Bordetella pertussis autotransporter Vag8 binds human C1 esterase inhibitor and confers serum resistance. PLoS One 6(6):e20585","journal-title":"PLoS One"},{"issue":"8","key":"1259_CR40","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.3201\/eid1508.081511","volume":"15","author":"FR Mooi","year":"2009","unstructured":"Mooi FR, van Loo IH, van Gent M, He Q, Bart MJ, Heuvelman KJ, de Greeff SC, Diavatopoulos D, Teunis P, Nagelkerke N et al (2009) Bordetella pertussis strains with increased toxin production associated with pertussis resurgence. Emerg Infect Dis 15(8):1206\u20131213","journal-title":"Emerg Infect Dis"},{"issue":"8","key":"1259_CR41","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1084\/jem.20030255","volume":"199","author":"WW Lathem","year":"2004","unstructured":"Lathem WW, Bergsbaken T, Welch RA (2004) Potentiation of C1 esterase inhibitor by StcE, a metalloprotease secreted by Escherichia coli O157:H7. J Exp Med 199(8):1077\u20131087","journal-title":"J Exp Med"},{"issue":"2","key":"1259_CR42","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1046\/j.1365-2958.2002.02997.x","volume":"45","author":"WW Lathem","year":"2002","unstructured":"Lathem WW, Grys TE, Witowski SE, Torres AG, Kaper JB, Tarr PI, Welch RA (2002) StcE, a metalloprotease secreted by Escherichia coli O157:H7, specifically cleaves C1 esterase inhibitor. Mol Microbiol 45(2):277\u2013288","journal-title":"Mol Microbiol"},{"issue":"9","key":"1259_CR43","doi-asserted-by":"crossref","first-page":"3638","DOI":"10.1128\/IAI.65.9.3638-3643.1997","volume":"65","author":"K Berggard","year":"1997","unstructured":"Berggard K, Johnsson E, Mooi FR, Lindahl G (1997) Bordetella pertussis binds the human complement regulator C4BP: role of filamentous hemagglutinin. Infect Immun 65(9):3638\u20133643","journal-title":"Infect Immun"},{"issue":"9","key":"1259_CR44","doi-asserted-by":"publisher","first-page":"2771","DOI":"10.1002\/1521-4141(200109)31:9<2771::AID-IMMU2771>3.0.CO;2-0","volume":"31","author":"K Berggard","year":"2001","unstructured":"Berggard K, Lindahl G, Dahlback B, Blom AM (2001) Bordetella pertussis binds to human C4b-binding protein (C4BP) at a site similar to that used by the natural ligand C4b. Eur J Immunol 31(9):2771\u20132780","journal-title":"Eur J Immunol"},{"issue":"1","key":"1259_CR45","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1111\/j.1574-6968.1998.tb13026.x","volume":"163","author":"RC Fernandez","year":"1998","unstructured":"Fernandez RC, Weiss AA (1998) Serum resistance in bvg-regulated mutants of Bordetella pertussis. FEMS Microbiol Lett 163(1):57\u201363","journal-title":"FEMS Microbiol Lett"},{"issue":"5","key":"1259_CR46","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.tim.2007.03.005","volume":"15","author":"MC Schneider","year":"2007","unstructured":"Schneider MC, Exley RM, Ram S, Sim RB, Tang CM (2007) Interactions between Neisseria meningitidis and the complement system. Trends Microbiol 15(5):233\u2013240","journal-title":"Trends Microbiol"},{"issue":"2\u20134","key":"1259_CR47","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0161-5890(03)00108-1","volume":"40","author":"H Jarva","year":"2003","unstructured":"Jarva H, Jokiranta TS, Wurzner R, Meri S (2003) Complement resistance mechanisms of streptococci. Mol Immunol 40(2\u20134):95\u2013107","journal-title":"Mol Immunol"},{"issue":"1","key":"1259_CR48","doi-asserted-by":"crossref","first-page":"375","DOI":"10.4049\/jimmunol.154.1.375","volume":"154","author":"A Thern","year":"1995","unstructured":"Thern A, Stenberg L, Dahlback B, Lindahl G (1995) Ig-binding surface proteins of Streptococcus pyogenes also bind human C4b-binding protein (C4BP), a regulatory component of the complement system. J Immunol 154(1):375\u2013386","journal-title":"J Immunol"},{"issue":"4","key":"1259_CR49","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1111\/j.1365-2567.2006.02323.x","volume":"117","author":"DG Wooster","year":"2006","unstructured":"Wooster DG, Maruvada R, Blom AM, Prasadarao NV (2006) Logarithmic phase Escherichia coli K1 efficiently avoids serum killing by promoting C4bp-mediated C3b and C4b degradation. Immunology 117(4):482\u2013493","journal-title":"Immunology"},{"issue":"4","key":"1259_CR50","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1016\/j.molimm.2010.11.015","volume":"48","author":"H Amdahl","year":"2011","unstructured":"Amdahl H, Jarva H, Haanpera M, Mertsola J, He Q, Jokiranta TS, Meri S (2011) Interactions between Bordetella pertussis and the complement inhibitor factor H. Mol Immunol 48(4):697\u2013705","journal-title":"Mol Immunol"},{"issue":"4","key":"1259_CR51","doi-asserted-by":"publisher","first-page":"e1003308","DOI":"10.1371\/journal.ppat.1003308","volume":"9","author":"T Meri","year":"2013","unstructured":"Meri T, Amdahl H, Lehtinen MJ, Hyvarinen S, McDowell JV, Bhattacharjee A, Meri S, Marconi R, Goldman A, Jokiranta TS (2013) Microbes bind complement inhibitor factor H via a common site. PLoS Pathog 9(4):e1003308","journal-title":"PLoS Pathog"},{"issue":"8","key":"1259_CR52","doi-asserted-by":"publisher","first-page":"e105011","DOI":"10.1371\/journal.pone.0105011","volume":"9","author":"D Gouw","year":"2014","unstructured":"Gouw D, Jonge MI, Hermans PW, Wessels HJ, Zomer A, Berends A, Pratt C, Berbers GA, Mooi FR, Diavatopoulos DA (2014) Proteomics-identified Bvg-activated autotransporters protect against Bordetella pertussis in a mouse model. PLoS One 9(8):e105011","journal-title":"PLoS One"},{"issue":"9816","key":"1259_CR53","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1016\/S0140-6736(11)61713-3","volume":"379","author":"ME Santolaya","year":"2012","unstructured":"Santolaya ME, O\u2019Ryan ML, Valenzuela MT, Prado V, Vergara R, Munoz A, Toneatto D, Grana G, Wang H, Clemens R et al (2012) Immunogenicity and tolerability of a multicomponent meningococcal serogroup B (4CMenB) vaccine in healthy adolescents in Chile: a phase 2b\/3 randomised, observer-blind, placebo-controlled study. Lancet 379(9816):617\u2013624","journal-title":"Lancet"},{"issue":"12","key":"1259_CR54","doi-asserted-by":"publisher","first-page":"7566","DOI":"10.4049\/jimmunol.176.12.7566","volume":"176","author":"MC Schneider","year":"2006","unstructured":"Schneider MC, Exley RM, Chan H, Feavers I, Kang YH, Sim RB, Tang CM (2006) Functional significance of factor H binding to Neisseria meningitidis. J Immunol 176(12):7566\u20137575","journal-title":"J Immunol"},{"issue":"1","key":"1259_CR55","doi-asserted-by":"publisher","first-page":"501","DOI":"10.4049\/jimmunol.177.1.501","volume":"177","author":"G Madico","year":"2006","unstructured":"Madico G, Welsch JA, Lewis LA, McNaughton A, Perlman DH, Costello CE, Ngampasutadol J, Vogel U, Granoff DM, Ram S (2006) The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance. J Immunol 177(1):501\u2013510","journal-title":"J Immunol"},{"issue":"6","key":"1259_CR56","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1038\/nrmicro2366","volume":"8","author":"D Serruto","year":"2010","unstructured":"Serruto D, Rappuoli R, Scarselli M, Gros P, van Strijp JA (2010) Molecular mechanisms of complement evasion: learning from staphylococci and meningococci. Nat Rev Microbiol 8(6):393\u2013399","journal-title":"Nat Rev Microbiol"},{"issue":"Suppl 8","key":"1259_CR57","doi-asserted-by":"publisher","first-page":"I113","DOI":"10.1016\/j.vaccine.2008.11.058","volume":"26","author":"S Meri","year":"2008","unstructured":"Meri S, Jordens M, Jarva H (2008) Microbial complement inhibitors as vaccines. Vaccine 26(Suppl 8):I113\u2013I117","journal-title":"Vaccine"},{"issue":"4","key":"1259_CR58","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1086\/603540","volume":"200","author":"I Santi","year":"2009","unstructured":"Santi I, Maione D, Galeotti CL, Grandi G, Telford JL, Soriani M (2009) BibA induces opsonizing antibodies conferring in vivo protection against group B Streptococcus. J Infect Dis 200(4):564\u2013570","journal-title":"J Infect Dis"},{"issue":"9","key":"1259_CR59","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1016\/j.ijporl.2014.06.024","volume":"78","author":"PA Schachern","year":"2014","unstructured":"Schachern PA, Tsuprun V, Ferrieri P, Briles DE, Goetz S, Cureoglu S, Paparella MM, Juhn S (2014) Pneumococcal PspA and PspC proteins: potential vaccine candidates for experimental otitis media. Int J Pediatr Otorhinolaryngol 78(9):1517\u20131521","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"22","key":"1259_CR60","doi-asserted-by":"publisher","first-page":"13410","DOI":"10.1128\/JVI.01205-14","volume":"88","author":"H Katsura","year":"2014","unstructured":"Katsura H, Piao Z, Iwatsuki-Horimoto K, Akeda Y, Watanabe S, Horimoto T, Oishi K, Kawaoka Y (2014) A bivalent vaccine based on a replication-incompetent influenza virus protects against Streptococcus pneumoniae and influenza virus infection. J Virol 88(22):13410\u201313417","journal-title":"J Virol"},{"issue":"4","key":"1259_CR61","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1111\/apm.12000","volume":"121","author":"K Grondahl-Yli-Hannuksela","year":"2013","unstructured":"Grondahl-Yli-Hannuksela K, Viander M, Mertsola J, He Q (2013) Increased risk of pertussis in adult patients with mannose-binding lectin deficiency. APMIS Acta Pathol Microbiol Immunol Scand 121(4):311\u2013315","journal-title":"APMIS Acta Pathol Microbiol Immunol Scand"}],"container-title":["Journal of Molecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00109-015-1259-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00109-015-1259-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00109-015-1259-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00109-015-1259-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T18:17:22Z","timestamp":1692555442000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00109-015-1259-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,18]]},"references-count":61,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["1259"],"URL":"https:\/\/doi.org\/10.1007\/s00109-015-1259-1","relation":{},"ISSN":["0946-2716"],"issn-type":[{"value":"0946-2716","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2,18]]}}}