{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T02:16:35Z","timestamp":1777428995516,"version":"3.51.4"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,8,20]],"date-time":"2016-08-20T00:00:00Z","timestamp":1471651200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31301154"],"award-info":[{"award-number":["31301154"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81430013"],"award-info":[{"award-number":["81430013"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Beijing Municipal Natural Science Foundation","doi-asserted-by":"publisher","award":["5144025"],"award-info":[{"award-number":["5144025"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Project of Construction of Innovative Teams and Teacher Career Development for Universities and Colleges Under Beijing Municipality","award":["IDHT20150502"],"award-info":[{"award-number":["IDHT20150502"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Mol Med"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1007\/s00109-016-1460-x","type":"journal-article","created":{"date-parts":[[2016,8,20]],"date-time":"2016-08-20T02:30:35Z","timestamp":1471660235000},"page":"69-82","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["HuR mediates motility of human bone marrow-derived mesenchymal stem cells triggered by sphingosine 1-phosphate in liver fibrosis"],"prefix":"10.1007","volume":"95","author":[{"given":"Na","family":"Chang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjing","family":"Ge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Xiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongxin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianghui","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jieshi","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liying","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,8,20]]},"reference":[{"key":"1460_CR1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1172\/JCI24282","volume":"115","author":"R Bataller","year":"2005","unstructured":"Bataller R, Brenner DA (2005) Liver fibrosis. J Clin Invest 115:209\u2013218","journal-title":"J Clin Invest"},{"key":"1460_CR2","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1053\/j.gastro.2008.03.003","volume":"134","author":"SL Friedman","year":"2008","unstructured":"Friedman SL (2008) Mechanisms of hepatic fibrogenesis. Gastroenterology 134:1655\u20131669","journal-title":"Gastroenterology"},{"issue":"Suppl 2","key":"1460_CR3","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1440-1746.2011.07002.x","volume":"27","author":"K Iwaisako","year":"2012","unstructured":"Iwaisako K, Brenner DA, Kisseleva T (2012) What\u2019s new in liver fibrosis? The origin of myofibroblasts in liver fibrosis. J Gastroenterol Hepatol 27(Suppl 2):65\u201368","journal-title":"J Gastroenterol Hepatol"},{"key":"1460_CR4","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1053\/j.gastro.2006.01.036","volume":"130","author":"FP Russo","year":"2006","unstructured":"Russo FP, Alison MR, Bigger BW, Amofah E, Florou A, Amin F, Bou Gharios G, Jeffery R, Iredale JP, Forbes SJ (2006) The bone marrow functionally contributes to liver fibrosis. Gastroenterology 130:1807\u20131821","journal-title":"Gastroenterology"},{"key":"1460_CR5","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1016\/j.jhep.2009.01.028","volume":"50","author":"C Li","year":"2009","unstructured":"Li C, Kong Y, Wang H, Wang S, Yu H, Liu X, Yang L, Jiang X, Li L, Li L (2009) Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis. J Hepatol 50:1174\u20131183","journal-title":"J Hepatol"},{"key":"1460_CR6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.ajpath.2012.03.014","volume":"181","author":"L Yang","year":"2012","unstructured":"Yang L, Chang N, Liu X, Han Z, Zhu T, Li C, Yang L, Li L (2012) Bone marrow-derived mesenchymal stem cells differentiate to hepatic myofibroblasts by transforming growth factor-beta1 via sphingosine kinase\/sphingosine 1-phosphate (S1P)\/S1P receptor axis. Am J Pathol 181:85\u201397","journal-title":"Am J Pathol"},{"key":"1460_CR7","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.bbalip.2012.07.022","volume":"1831","author":"S Schwalm","year":"2013","unstructured":"Schwalm S, Pfeilschifter J, Huwiler A (2013) Sphingosine-1-phosphate: a Janus-Faced Mediator of fibrotic diseases. Biochim Biophys Acta 1831:239\u2013250","journal-title":"Biochim Biophys Acta"},{"key":"1460_CR8","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.bbalip.2012.06.008","volume":"1831","author":"Y Takuwa","year":"2013","unstructured":"Takuwa Y, Ikeda H, Okamoto Y, Takuwa N, Yoshioka K (2013) Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases. Biochim Biophys Acta 1831:185\u2013192","journal-title":"Biochim Biophys Acta"},{"key":"1460_CR9","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.bbalip.2012.07.003","volume":"1831","author":"NJ Pyne","year":"2013","unstructured":"Pyne NJ, Dubois G, Pyne S (2013) Role of sphingosine 1-phosphate and lysophosphatidic acid in fibrosis. Biochim Biophys Acta 1831:228\u2013238","journal-title":"Biochim Biophys Acta"},{"key":"1460_CR10","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.jaci.2014.01.037","volume":"134","author":"H Sic","year":"2014","unstructured":"Sic H, Kraus H, Madl J, Flittner KA, von Munchow AL, Pieper K, Rizzi M, Kienzler AK, Ayata K, Rauer S, et al. (2014) Sphingosine-1-phosphate receptors control B-cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia, and multiple sclerosis. J Allergy Clin Immunol 134:420\u2013428","journal-title":"J Allergy Clin Immunol"},{"key":"1460_CR11","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1189\/jlb.3AB1013-567R","volume":"96","author":"S Mahajan-Thakur","year":"2014","unstructured":"Mahajan-Thakur S, Sostmann BD, Fender AC, Behrendt D, Felix SB, Schror K, Rauch BH (2014) Sphingosine-1-phosphate induces thrombin receptor PAR-4 expression to enhance cell migration and COX-2 formation in human monocytes. J Leukoc Biol 96:611\u2013618","journal-title":"J Leukoc Biol"},{"key":"1460_CR12","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.2353\/ajpath.2009.090037","volume":"175","author":"C Li","year":"2009","unstructured":"Li C, Jiang X, Yang L, Liu X, Yue S, Li L (2009) Involvement of sphingosine 1-phosphate (SIP)\/S1P3 signaling in cholestasis-induced liver fibrosis. Am J Pathol 175:1464\u20131472","journal-title":"Am J Pathol"},{"key":"1460_CR13","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1002\/jcp.22572","volume":"226","author":"X Liu","year":"2011","unstructured":"Liu X, Yue S, Li C, Yang L, You H, Li L (2011) Essential roles of sphingosine 1-phosphate receptor types 1 and 3 in human hepatic stellate cells motility and activation. J Cell Physiol 226:2370\u20132377","journal-title":"J Cell Physiol"},{"key":"1460_CR14","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.jhep.2010.08.028","volume":"54","author":"C Li","year":"2011","unstructured":"Li C, Zheng S, You H, Liu X, Lin M, Yang L, Li L (2011) Sphingosine 1-phosphate (S1P)\/S1P receptors are involved in human liver fibrosis by action on hepatic myofibroblasts motility. J Hepatol 54:1205\u20131213","journal-title":"J Hepatol"},{"key":"1460_CR15","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1002\/jcb.20127","volume":"92","author":"T Sanchez","year":"2004","unstructured":"Sanchez T, Hla T (2004) Structural and functional characteristics of S1P receptors. J Cell Biochem 92:913\u2013922","journal-title":"J Cell Biochem"},{"key":"1460_CR16","doi-asserted-by":"crossref","first-page":"3306","DOI":"10.1002\/eji.201343441","volume":"43","author":"B Weichand","year":"2013","unstructured":"Weichand B, Weis N, Weigert A, Grossmann N, Levkau B, Br\u00fcne B (2013) Apoptotic cells enhance sphingosine-1-phosphate receptor 1 dependent macrophage migration. Eur J Immunol 43:3306\u20133313","journal-title":"Eur J Immunol"},{"key":"1460_CR17","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1016\/j.bbalip.2013.07.011","volume":"1831","author":"A Koch","year":"2013","unstructured":"Koch A, V\u00f6lzke A, Puff B, Blankenbach K, Meyer Zu Heringdorf D, Huwiler A, Pfeilschifter J (2013) PPAR\u03b3 agonists upregulate sphingosine 1-phosphate (S1P) receptor 1 expression, which in turn reduces S1P-induced [Ca2+]i increases in renal mesangial cells. Biochimica et Biophys Acta (BBA) - Mol Cell Biol Lipids 1831:1634\u20131643","journal-title":"Biochimica et Biophys Acta (BBA) - Mol Cell Biol Lipids"},{"key":"1460_CR18","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1172\/JCI31123","volume":"117","author":"A Skoura","year":"2007","unstructured":"Skoura A, Sanchez T, Claffey K, Mandala SM, Proia RL, Hla T (2007) Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina. J Clin Invest 117:2506\u20132516","journal-title":"J Clin Invest"},{"key":"1460_CR19","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1091\/mbc.E09-09-0812","volume":"21","author":"F Cencetti","year":"2010","unstructured":"Cencetti F, Bernacchioni C, Nincheri P, Donati C, Bruni P (2010) Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via up-regulation of sphingosine kinase-1\/S1P3 axis. Mol Biol Cell 21:1111\u20131124","journal-title":"Mol Biol Cell"},{"key":"1460_CR20","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1002\/jcb.24670","volume":"115","author":"N Chang","year":"2014","unstructured":"Chang N, Xiu L, Li L (2014) Sphingosine 1-phosphate receptors negatively regulate collagen type I\/III expression in human bone marrow-derived mesenchymal stem cell. J Cell Biochem 115:359\u2013367","journal-title":"J Cell Biochem"},{"key":"1460_CR21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.gde.2012.12.006","volume":"23","author":"LE Simone","year":"2013","unstructured":"Simone LE, Keene JD (2013) Mechanisms coordinating ELAV\/Hu mRNA regulons. Curr Opin Genet Dev 23:35\u201343","journal-title":"Curr Opin Genet Dev"},{"key":"1460_CR22","doi-asserted-by":"crossref","first-page":"189","DOI":"10.2741\/3921","volume":"17","author":"S Srikantan","year":"2012","unstructured":"Srikantan S, Gorospe M (2012) HuR function in disease. Front Biosci (Landmark Ed) 17:189\u2013205","journal-title":"Front Biosci (Landmark Ed)"},{"key":"1460_CR23","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1002\/hep.25828","volume":"56","author":"A Woodhoo","year":"2012","unstructured":"Woodhoo A, Iruarrizaga-Lejarreta M, Beraza N, Garcia-Rodriguez JL, Embade N, Fernandez-Ramos D, Martinez-Lopez N, Gutierrez-De JV, Arteta B, Caballeria J, et al. (2012) Human antigen R contributes to hepatic stellate cell activation and liver fibrosis. Hepatology 56:1870\u20131882","journal-title":"Hepatology"},{"key":"1460_CR24","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1016\/j.cellsig.2012.03.003","volume":"24","author":"D Bai","year":"2012","unstructured":"Bai D, Gao Q, Li C, Ge L, Gao Y, Wang H (2012) A conserved TGFbeta1\/HuR feedback circuit regulates the fibrogenic response in fibroblasts. Cell Signal 24:1426\u20131432","journal-title":"Cell Signal"},{"issue":"Pt 21","key":"1460_CR25","doi-asserted-by":"crossref","first-page":"3145","DOI":"10.1242\/jcs.111.21.3145","volume":"111","author":"U Atasoy","year":"1998","unstructured":"Atasoy U, Watson J, Patel D, Keene JD (1998) ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. J Cell Sci 111(Pt 21):3145\u20133156","journal-title":"J Cell Sci"},{"key":"1460_CR26","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.4049\/jimmunol.180.2.1239","volume":"180","author":"AM Johann","year":"2008","unstructured":"Johann AM, Weigert A, Eberhardt W, Kuhn AM, Barra V, von Knethen A, Pfeilschifter JM, Brune B (2008) Apoptotic cell-derived sphingosine-1-phosphate promotes HuR-dependent cyclooxygenase-2 mRNA stabilization and protein expression. J Immunol 180:1239\u20131248","journal-title":"J Immunol"},{"key":"1460_CR27","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1128\/MCB.01373-09","volume":"30","author":"A Doller","year":"2010","unstructured":"Doller A, Schlepckow K, Schwalbe H, Pfeilschifter J, Eberhardt W (2010) Tandem phosphorylation of serines 221 and 318 by protein kinase Cdelta coordinates mRNA binding and nucleocytoplasmic shuttling of HuR. Mol Cell Biol 30:1397\u20131410","journal-title":"Mol Cell Biol"},{"key":"1460_CR28","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1074\/mcp.T500024-MCP200","volume":"5","author":"E Kinoshita","year":"2005","unstructured":"Kinoshita E (2005) Phosphate-binding tag, a new tool to visualize phosphorylated proteins. Mol Cell Proteomics 5:749\u2013757","journal-title":"Mol Cell Proteomics"},{"key":"1460_CR29","doi-asserted-by":"crossref","first-page":"22141","DOI":"10.1038\/srep22141","volume":"6","author":"J Ge","year":"2016","unstructured":"Ge J, Chang N, Zhao Z, Tian L, Duan X, Yang L, Li L (2016) Essential roles of RNA-binding protein HuR in activation of hepatic stellate cells induced by transforming growth factor-beta1. Sci Rep 6:22141","journal-title":"Sci Rep"},{"key":"1460_CR30","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1093\/nar\/gkp1114","volume":"38","author":"J Yi","year":"2010","unstructured":"Yi J, Chang N, Liu X, Guo G, Xue L, Tong T, Gorospe M, Wang W (2010) Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence. Nucleic Acids Res 38:1547\u20131558","journal-title":"Nucleic Acids Res"},{"key":"1460_CR31","doi-asserted-by":"crossref","first-page":"372","DOI":"10.2174\/138920312801619394","volume":"13","author":"S Srikantan","year":"2012","unstructured":"Srikantan S, Tominaga K, Gorospe M (2012) Functional interplay between RNA-binding protein HuR and microRNAs. Curr Protein Pept Sci 13:372\u2013379","journal-title":"Curr Protein Pept Sci"},{"key":"1460_CR32","doi-asserted-by":"crossref","first-page":"380","DOI":"10.2174\/138920312801619439","volume":"13","author":"W Eberhardt","year":"2012","unstructured":"Eberhardt W, Doller A, Pfeilschifter J (2012) Regulation of the mRNA-binding protein HuR by posttranslational modification: spotlight on phosphorylation. Curr Protein Pept Sci 13:380\u2013390","journal-title":"Curr Protein Pept Sci"},{"key":"1460_CR33","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1016\/j.cellsig.2008.05.007","volume":"20","author":"A Doller","year":"2008","unstructured":"Doller A, Pfeilschifter J, Eberhardt W (2008) Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR. Cell Signal 20:2165\u20132173","journal-title":"Cell Signal"},{"key":"1460_CR34","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1093\/carcin\/bgr024","volume":"32","author":"A Doller","year":"2011","unstructured":"Doller A, Winkler C, Azrilian I, Schulz S, Hartmann S, Pfeilschifter J, Eberhardt W (2011) High-constitutive HuR phosphorylation at Ser 318 by PKC{delta} propagates tumor relevant functions in colon carcinoma cells. Carcinogenesis 32:676\u2013685","journal-title":"Carcinogenesis"},{"key":"1460_CR35","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1002\/jcp.24795","volume":"230","author":"CK Hsu","year":"2015","unstructured":"Hsu CK, Lee IT, Lin CC, Hsiao LD, Yang CM (2015) Sphingosine-1-phosphate mediates COX-2 expression and PGE2 \/IL-6 secretion via c-Src-dependent AP-1 activation. J Cell Physiol 230:702\u2013715","journal-title":"J Cell Physiol"},{"key":"1460_CR36","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.pharmthera.2007.04.006","volume":"115","author":"V Brinkmann","year":"2007","unstructured":"Brinkmann V (2007) Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology. Pharmacol Ther 115:84\u2013105","journal-title":"Pharmacol Ther"},{"key":"1460_CR37","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1172\/JCI45021","volume":"122","author":"A Yiakouvaki","year":"2012","unstructured":"Yiakouvaki A, Dimitriou M, Karakasiliotis I, Eftychi C, Theocharis S, Kontoyiannis DL (2012) Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis. J Clin Invest 122:48\u201361","journal-title":"J Clin Invest"},{"key":"1460_CR38","doi-asserted-by":"crossref","first-page":"575","DOI":"10.4161\/rna.6.5.10079","volume":"6","author":"X Guo","year":"2009","unstructured":"Guo X, Wu Y, Hartley RS (2009) MicroRNA-125a represses cell growth by targeting HuR in breast cancer. RNA Biol 6:575\u2013583","journal-title":"RNA Biol"},{"key":"1460_CR39","doi-asserted-by":"crossref","first-page":"5365","DOI":"10.1128\/MCB.00113-07","volume":"27","author":"V Dormoy-Raclet","year":"2007","unstructured":"Dormoy-Raclet V, Menard I, Clair E, Kurban G, Mazroui R, Di Marco S, von Roretz C, Pause A, Gallouzi IE (2007) The RNA-binding protein HuR promotes cell migration and cell invasion by stabilizing the beta-actin mRNA in a U-rich-element-dependent manner. Mol Cell Biol 27:5365\u20135380","journal-title":"Mol Cell Biol"},{"key":"1460_CR40","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1093\/carcin\/bgu080","volume":"35","author":"N Al-Souhibani","year":"2014","unstructured":"Al-Souhibani N, Al-Ghamdi M, Al-Ahmadi W, Khabar KS (2014) Posttranscriptional control of the chemokine receptor CXCR4 expression in cancer cells. Carcinogenesis 35:1983\u20131992","journal-title":"Carcinogenesis"},{"key":"1460_CR41","doi-asserted-by":"crossref","first-page":"3168","DOI":"10.1007\/s00018-008-8252-6","volume":"65","author":"MN Hinman","year":"2008","unstructured":"Hinman MN, Lou H (2008) Diverse molecular functions of Hu proteins. Cell Mol Life Sci 65:3168\u20133181","journal-title":"Cell Mol Life Sci"},{"key":"1460_CR42","doi-asserted-by":"crossref","first-page":"7905","DOI":"10.1093\/nar\/gkt565","volume":"41","author":"R Zhuang","year":"2013","unstructured":"Zhuang R, Rao JN, Zou T, Liu L, Xiao L, Cao S, Hansraj NZ, Gorospe M, Wang JY (2013) miR-195 competes with HuR to modulate stim1 mRNA stability and regulate cell migration. Nucleic Acids Res 41:7905\u20137919","journal-title":"Nucleic Acids Res"},{"key":"1460_CR43","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1053\/j.gastro.2012.04.007","volume":"142","author":"XW Wang","year":"2012","unstructured":"Wang XW, Heegaard NH, Orum H (2012) MicroRNAs in liver disease. Gastroenterology 142:1431\u20131443","journal-title":"Gastroenterology"},{"key":"1460_CR44","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.7432","author":"D Sohn","year":"2016","unstructured":"Sohn D, Peters D, Piekorz RP, Budach W, Janicke RU (2016) miR-30e controls DNA damage-induced stress responses by modulating expression of the CDK inhibitor p21WAF1\/CIP1 and caspase-3. Oncotarget. doi: 10.18632\/oncotarget.7432","journal-title":"Oncotarget"},{"key":"1460_CR45","doi-asserted-by":"crossref","first-page":"E182","DOI":"10.3390\/ijms17020182","volume":"17","author":"BW Zhang","year":"2016","unstructured":"Zhang BW, Cai HF, Wei XF, Sun JJ, Lan XY, Lei CZ, Lin FP, Qi XL, Plath M, Chen H (2016) miR-30-5p Regulates Muscle Differentiation and Alternative Splicing of Muscle-Related Genes by Targeting MBNL. Int J Mol Sci 17:E182","journal-title":"Int J Mol Sci"},{"key":"1460_CR46","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1111\/febs.13238","volume":"282","author":"SY Kwak","year":"2015","unstructured":"Kwak SY, Kim BY, Ahn HJ, Yoo JO, Kim J, Bae IH, Han YH (2015) Ionizing radiation-inducible miR-30e promotes glioma cell invasion through EGFR stabilization by directly targeting CBL-B. Febs J 282:1512\u20131525","journal-title":"Febs J"},{"key":"1460_CR47","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/ki.2013.80","volume":"84","author":"L Jiang","year":"2013","unstructured":"Jiang L, Qiu W, Zhou Y, Wen P, Fang L, Cao H, Zen K, He W, Zhang C, Dai C, Yang J (2013) A microRNA-30e\/mitochondrial uncoupling protein 2 axis mediates TGF-beta1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis. Kidney Int 84:285\u2013296","journal-title":"Kidney Int"},{"key":"1460_CR48","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1093\/cvr\/cvv030","volume":"106","author":"W Ding","year":"2015","unstructured":"Ding W, Li J, Singh J, Alif R, Vazquez-Padron RI, Gomes SA, Hare JM, Shehadeh LA (2015) miR-30e targets IGF2-regulated osteogenesis in bone marrow-derived mesenchymal stem cells, aortic smooth muscle cells, and ApoE\u2212\/\u2212 mice. Cardiovasc Res 106:131\u2013142","journal-title":"Cardiovasc Res"},{"key":"1460_CR49","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1093\/nar\/gkt903","volume":"42","author":"JH Yoon","year":"2013","unstructured":"Yoon JH, Abdelmohsen K, Srikantan S, Guo R, Yang X, Martindale JL, Gorospe M (2013) Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs. Nucleic Acids Res 42:1196\u20131208","journal-title":"Nucleic Acids Res"}],"container-title":["Journal of Molecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00109-016-1460-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00109-016-1460-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00109-016-1460-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00109-016-1460-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T19:39:15Z","timestamp":1657136355000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00109-016-1460-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,20]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["1460"],"URL":"https:\/\/doi.org\/10.1007\/s00109-016-1460-x","relation":{},"ISSN":["0946-2716","1432-1440"],"issn-type":[{"value":"0946-2716","type":"print"},{"value":"1432-1440","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,20]]}}}