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The Institutional Research and Ethics Committee at Hospital Cl\u00ednic de Barcelona approved the present study (<i>Comit\u00e9 de \u00c9tica de la Investigaci\u00f3n con medicamentos del Hospital Cl\u00ednic de Barcelona<\/i>). The Institutional Research and Ethics Committee at Hospital Regional Universitario de M\u00e1laga approved the present study (<i>Comit\u00e9 de \u00c9tica de la Investigaci\u00f3n Provincial de M\u00e1laga<\/i>).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Written informed consent was obtained from all participants prior to study inclusion and are available under considerable request.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable. No personal nor any clinical details of participants are presented.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}