{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T10:41:34Z","timestamp":1764240094425,"version":"3.37.3"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"11-12","license":[{"start":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T00:00:00Z","timestamp":1507507200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"National Science & Technology Pillar Program of China","award":["2013BAI12B01-3"],"award-info":[{"award-number":["2013BAI12B01-3"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81220108026","81430089","81473290"],"award-info":[{"award-number":["81220108026","81430089","81473290"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81703631"],"award-info":[{"award-number":["81703631"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Hubei Province Health and Family Planning Scientific Research Project","award":["WJ2017C0003","WJ2017M028"],"award-info":[{"award-number":["WJ2017C0003","WJ2017M028"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Nat"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1007\/s00114-017-1510-4","type":"journal-article","created":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T04:55:27Z","timestamp":1507524927000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Effects of prenatal caffeine exposure on glucose homeostasis of adult offspring rats"],"prefix":"10.1007","volume":"104","author":[{"given":"Hao","family":"Kou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gui-hua","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin-guo","family":"Pei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chai","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-fang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,10,9]]},"reference":[{"issue":"4","key":"1510_CR1","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/cpt1979254447","volume":"25","author":"A Aldridge","year":"1979","unstructured":"Aldridge A, Aranda JV et al (1979) Caffeine metabolism in the newborn. Clin Pharmacol Ther 25(4):447\u2013453","journal-title":"Clin Pharmacol Ther"},{"issue":"6","key":"1510_CR2","doi-asserted-by":"publisher","first-page":"1691","DOI":"10.3945\/ajcn.2009.28792","volume":"91","author":"R Bakker","year":"2010","unstructured":"Bakker R, Steegers EA et al (2010) Maternal caffeine intake from coffee and tea, fetal growth, and the risks of adverse birth outcomes: the Generation R Study. Am J Clin Nutr 91(6):1691\u20131698. \nhttps:\/\/doi.org\/10.3945\/ajcn.2009.28792","journal-title":"Am J Clin Nutr"},{"issue":"Pt B","key":"1510_CR3","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.jsbmb.2016.06.001","volume":"165","author":"FG Battiston","year":"2017","unstructured":"Battiston FG, Dos Santos C et al (2017) Glucose homeostasis in rats treated with 4-vinylcyclohexene diepoxide is not worsened by dexamethasone treatment. J Steroid Biochem Mol Biol 165(Pt B):170\u2013181. \nhttps:\/\/doi.org\/10.1016\/j.jsbmb.2016.06.001","journal-title":"J Steroid Biochem Mol Biol"},{"issue":"1 Pt 1","key":"1510_CR4","first-page":"E11","volume":"277","author":"E Bertin","year":"1999","unstructured":"Bertin E, Gangnerau MN et al (1999) Glucose metabolism and beta-cell mass in adult offspring of rats protein and\/or energy restricted during the last week of pregnancy. Am J Phys 277(1 Pt 1):E11\u2013E17","journal-title":"Am J Phys"},{"issue":"5","key":"1510_CR5","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1046\/j.1464-5491.2000.00288.x","volume":"17","author":"S Bo","year":"2000","unstructured":"Bo S, Cavallo-Perin P et al (2000) Low birthweight and metabolic abnormalities in twins with increased susceptibility to Type 2 diabetes mellitus. Diabet Med: J Br Diabet Assoc 17(5):365\u2013370","journal-title":"Diabet Med: J Br Diabet Assoc"},{"issue":"2","key":"1510_CR6","doi-asserted-by":"publisher","first-page":"R101","DOI":"10.1152\/ajpregu.00068.2017","volume":"313","author":"LE Camacho","year":"2017","unstructured":"Camacho LE, Chen X et al (2017) Enhanced insulin secretion and insulin sensitivity in young lambs with placental insufficiency-induced intrauterine growth restriction. Am J Physiol Regul Integr Comp Physiol 313(2):R101\u2013R109. \nhttps:\/\/doi.org\/10.1152\/ajpregu.00068.2017","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"1\u20132","key":"1510_CR7","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.resp.2009.04.024","volume":"168","author":"F Cayetanot","year":"2009","unstructured":"Cayetanot F, Larnicol N et al (2009) Antenatal environmental stress and maturation of the breathing control, experimental data. Respir Physiol Neurobiol 168(1\u20132):92\u2013100. \nhttps:\/\/doi.org\/10.1016\/j.resp.2009.04.024","journal-title":"Respir Physiol Neurobiol"},{"key":"1510_CR8","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1186\/s12916-014-0174-6","volume":"12","author":"LW Chen","year":"2014","unstructured":"Chen LW, Wu Y et al (2014) Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose-response meta-analysis. BMC Med 12:174. \nhttps:\/\/doi.org\/10.1186\/s12916-014-0174-6","journal-title":"BMC Med"},{"issue":"9","key":"1510_CR9","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1007\/s001250051021","volume":"41","author":"AD Cherrington","year":"1998","unstructured":"Cherrington AD, Edgerton D et al (1998) The direct and indirect effects of insulin on hepatic glucose production in vivo. Diabetologia 41(9):987\u2013996. \nhttps:\/\/doi.org\/10.1007\/s001250051021","journal-title":"Diabetologia"},{"issue":"1","key":"1510_CR10","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.jada.2004.10.027","volume":"105","author":"CD Frary","year":"2005","unstructured":"Frary CD, Johnson RK et al (2005) Food sources and intakes of caffeine in the diets of persons in the United States. J Am Diet Assoc 105(1):110\u2013113. \nhttps:\/\/doi.org\/10.1016\/j.jada.2004.10.027","journal-title":"J Am Diet Assoc"},{"issue":"1","key":"1510_CR11","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1210\/en.2012-1640","volume":"154","author":"M Garg","year":"2013","unstructured":"Garg M, Thamotharan M et al (2013) Glucose intolerance and lipid metabolic adaptations in response to intrauterine and postnatal calorie restriction in male adult rats. Endocrinology 154(1):102\u2013113. \nhttps:\/\/doi.org\/10.1210\/en.2012-1640","journal-title":"Endocrinology"},{"issue":"10","key":"1510_CR12","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1007\/s001250050812","volume":"40","author":"A Garofano","year":"1997","unstructured":"Garofano A, Czernichow P et al (1997) In utero undernutrition impairs rat beta-cell development. Diabetologia 40(10):1231\u20131234. \nhttps:\/\/doi.org\/10.1007\/s001250050812","journal-title":"Diabetologia"},{"issue":"1","key":"1510_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/ajhb.20590","volume":"19","author":"PD Gluckman","year":"2007","unstructured":"Gluckman PD, Hanson MA et al (2007) Early life events and their consequences for later disease: a life history and evolutionary perspective. Am J Hum Biol: Off J Hum Biol Counc 19(1):1\u201319. \nhttps:\/\/doi.org\/10.1002\/ajhb.20590","journal-title":"Am J Hum Biol: Off J Hum Biol Counc"},{"issue":"11","key":"1510_CR14","doi-asserted-by":"publisher","first-page":"2213","DOI":"10.1007\/s00125-005-1930-0","volume":"48","author":"IF Godsland","year":"2005","unstructured":"Godsland IF (2005) Oestrogens and insulin secretion. Diabetologia 48(11):2213\u20132220. \nhttps:\/\/doi.org\/10.1007\/s00125-005-1930-0","journal-title":"Diabetologia"},{"issue":"8","key":"1510_CR15","doi-asserted-by":"publisher","first-page":"1593","DOI":"10.1038\/oby.2009.449","volume":"18","author":"AK Gosby","year":"2010","unstructured":"Gosby AK, Maloney CA et al (2010) Elevated insulin sensitivity in low-protein offspring rats is prevented by a high-fat diet and is associated with visceral fat. Obesity 18(8):1593\u20131600. \nhttps:\/\/doi.org\/10.1038\/oby.2009.449","journal-title":"Obesity"},{"key":"1510_CR16","doi-asserted-by":"publisher","first-page":"a2332","DOI":"10.1136\/bmj.a2332","volume":"337","author":"Group CS","year":"2008","unstructured":"Group CS (2008) Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study. BMJ 337:a2332. \nhttps:\/\/doi.org\/10.1136\/bmj.a2332","journal-title":"BMJ"},{"key":"1510_CR17","doi-asserted-by":"publisher","unstructured":"Heikkinen S, Argmann CA, et al. (2007). Evaluation of glucose homeostasis. Curr Protoc Mol Biol Chapter 29: Unit 29B 23. doi:\nhttps:\/\/doi.org\/10.1002\/0471142727.mb29b03s77","DOI":"10.1002\/0471142727.mb29b03s77"},{"issue":"3","key":"1510_CR18","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1203\/00006450-200009000-00002","volume":"48","author":"DJ Hill","year":"2000","unstructured":"Hill DJ, Duvillie B (2000) Pancreatic development and adult diabetes. Pediatr Res 48(3):269\u2013274. \nhttps:\/\/doi.org\/10.1203\/00006450-200009000-00002","journal-title":"Pediatr Res"},{"issue":"6","key":"1510_CR19","doi-asserted-by":"crossref","first-page":"325","DOI":"10.2220\/biomedres.30.325","volume":"30","author":"T Inoue","year":"2009","unstructured":"Inoue T, Kido Y et al (2009) Effect of intrauterine undernutrition during late gestation on pancreatic beta cell mass. Biomed Res Tokyo 30(6):325\u2013330","journal-title":"Biomed Res Tokyo"},{"issue":"7450","key":"1510_CR20","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1136\/bmj.38077.458438.EE","volume":"328","author":"J James","year":"2004","unstructured":"James J, Thomas P et al (2004) Preventing childhood obesity by reducing consumption of carbonated drinks: cluster randomised controlled trial. Br Med J 328(7450):1237\u20131239. \nhttps:\/\/doi.org\/10.1136\/bmj.38077.458438.EE","journal-title":"Br Med J"},{"issue":"10","key":"1510_CR21","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.1016\/j.metabol.2005.05.005","volume":"54","author":"CB Jensen","year":"2005","unstructured":"Jensen CB, Storgaard H et al (2005) Young, low-birth-weight men are not more susceptible to the diabetogenic effects of a prolonged free fatty acid exposure than matched controls. Metab Clin Exp 54(10):1398\u20131406. \nhttps:\/\/doi.org\/10.1016\/j.metabol.2005.05.005","journal-title":"Metab Clin Exp"},{"key":"1510_CR22","doi-asserted-by":"publisher","unstructured":"Jha PK, Foppen E et al (2016) Sleep restriction acutely impairs glucose tolerance in rats. Physiol Rep 4(12). \n10.14814\/phy2.12839","DOI":"10.14814\/phy2.12839"},{"issue":"9270","key":"1510_CR23","doi-asserted-by":"publisher","first-page":"1798","DOI":"10.1016\/S0140-6736(00)04911-4","volume":"357","author":"HS Kahn","year":"2001","unstructured":"Kahn HS (2001) Glucose tolerance in adults after prenatal exposure to famine. Lancet 357(9270):1798\u20131799. \nhttps:\/\/doi.org\/10.1016\/S0140-6736(00)04911-4","journal-title":"Lancet"},{"issue":"11","key":"1510_CR24","doi-asserted-by":"publisher","first-page":"1663","DOI":"10.2337\/diabetes.42.11.1663","volume":"42","author":"SE Kahn","year":"1993","unstructured":"Kahn SE, Prigeon RL et al (1993) Quantification of the relationship between insulin sensitivity and beta-cell function in human-subjects\u2014evidence for a hyperbolic function. Diabetes 42(11):1663\u20131672. \nhttps:\/\/doi.org\/10.2337\/diabetes.42.11.1663","journal-title":"Diabetes"},{"key":"1510_CR25","first-page":"187","volume":"5","author":"R Knutti","year":"1982","unstructured":"Knutti R, Rothweiler H et al (1982) The effect of pregnancy on the pharmacokinetics of caffeine. Arch Toxicol Suppl = Archiv fur Toxikologie Supplement 5:187\u2013192","journal-title":"Arch Toxicol Suppl = Archiv fur Toxikologie Supplement"},{"key":"1510_CR26","doi-asserted-by":"publisher","unstructured":"Kou H, Liu Y et al (2014) Maternal glucocorticoid elevation and associated blood metabonome changes might be involved in metabolic programming of intrauterine growth retardation in rats exposed to caffeine prenatally. Toxicol Appl Pharmacol. \nhttps:\/\/doi.org\/10.1016\/j.taap.2014.01.007","DOI":"10.1016\/j.taap.2014.01.007"},{"issue":"1","key":"1510_CR27","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1071\/RD12262","volume":"25","author":"R Laguna-Barraza","year":"2012","unstructured":"Laguna-Barraza R, Bermejo-Alvarez P et al (2012) Sex-specific embryonic origin of postnatal phenotypic variability. Reprod Fertil Dev 25(1):38\u201347. \nhttps:\/\/doi.org\/10.1071\/RD12262","journal-title":"Reprod Fertil Dev"},{"issue":"4","key":"1510_CR28","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1203\/PDR.0b013e31822a65a3","volume":"70","author":"K Lim","year":"2011","unstructured":"Lim K, Armitage JA et al (2011) IUGR in the absence of postnatal \u201ccatch-up\u201d growth leads to improved whole body insulin sensitivity in rat offspring. Pediatr Res 70(4):339\u2013344","journal-title":"Pediatr Res"},{"issue":"2","key":"1510_CR29","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.taap.2012.05.002","volume":"262","author":"Y Liu","year":"2012","unstructured":"Liu Y, Xu D et al (2012) Fetal rat metabonome alteration by prenatal caffeine ingestion probably due to the increased circulatory glucocorticoid level and altered peripheral glucose and lipid metabolic pathways. Toxicol Appl Pharmacol 262(2):205\u2013216. \nhttps:\/\/doi.org\/10.1016\/j.taap.2012.05.002","journal-title":"Toxicol Appl Pharmacol"},{"issue":"3","key":"1510_CR30","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s11883-004-0030-9","volume":"6","author":"JF Louet","year":"2004","unstructured":"Louet JF, LeMay C et al (2004) Antidiabetic actions of estrogen: insight from human and genetic mouse models. Curr Atheroscler Rep 6(3):180\u2013185","journal-title":"Curr Atheroscler Rep"},{"issue":"3","key":"1510_CR31","doi-asserted-by":"publisher","first-page":"89","DOI":"10.4239\/wjd.v1.i3.89","volume":"1","author":"ZC Luo","year":"2010","unstructured":"Luo ZC, Xiao L et al (2010) Mechanisms of developmental programming of the metabolic syndrome and related disorders. World J Diabetes 1(3):89\u201398. \nhttps:\/\/doi.org\/10.4239\/wjd.v1.i3.89","journal-title":"World J Diabetes"},{"issue":"3","key":"1510_CR32","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.taap.2013.11.020","volume":"274","author":"H Luo","year":"2014","unstructured":"Luo H, Deng Z et al (2014) Prenatal caffeine ingestion induces transgenerational neuroendocrine metabolic programming alteration in second generation rats. Toxicol Appl Pharmacol 274(3):383\u2013392. \nhttps:\/\/doi.org\/10.1016\/j.taap.2013.11.020","journal-title":"Toxicol Appl Pharmacol"},{"key":"1510_CR33","doi-asserted-by":"publisher","DOI":"10.1038\/srep17746","volume":"5","author":"H Luo","year":"2015","unstructured":"Luo H, Li J et al (2015) Prenatal caffeine exposure induces a poor quality of articular cartilage in male adult offspring rats via cholesterol accumulation in cartilage. Sci Rep 5:17746. \nhttps:\/\/doi.org\/10.1038\/srep17746","journal-title":"Sci Rep"},{"issue":"1","key":"1510_CR34","doi-asserted-by":"publisher","first-page":"E15","DOI":"10.1152\/ajpendo.00645.2007","volume":"294","author":"R Muniyappa","year":"2008","unstructured":"Muniyappa R, Lee S et al (2008) Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Phys Endocrinol Metab 294(1):E15\u2013E26. \nhttps:\/\/doi.org\/10.1152\/ajpendo.00645.2007","journal-title":"Am J Phys Endocrinol Metab"},{"key":"1510_CR35","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1093\/Bmb\/60.1.143","volume":"60","author":"SE Ozanne","year":"2001","unstructured":"Ozanne SE (2001) Metabolic programming in animals. Br Med Bull 60:143\u2013152. \nhttps:\/\/doi.org\/10.1093\/Bmb\/60.1.143","journal-title":"Br Med Bull"},{"issue":"6 Pt 1","key":"1510_CR36","first-page":"E1128","volume":"271","author":"SE Ozanne","year":"1996","unstructured":"Ozanne SE, Wang CL et al (1996) Altered muscle insulin sensitivity in the male offspring of protein-malnourished rats. Am J Phys 271(6 Pt 1):E1128\u2013E1134","journal-title":"Am J Phys"},{"issue":"3","key":"1510_CR37","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1097\/MPA.0b013e31815ba826","volume":"36","author":"A Rafacho","year":"2008","unstructured":"Rafacho A, Giozzet VA et al (2008) Functional alterations in endocrine pancreas of rats with different degrees of dexamethasone-induced insulin resistance. Pancreas 36(3):284\u2013293. \nhttps:\/\/doi.org\/10.1097\/MPA.0b013e31815ba826","journal-title":"Pancreas"},{"issue":"1","key":"1510_CR38","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1210\/en.2009-0704","volume":"151","author":"A Rafacho","year":"2010","unstructured":"Rafacho A, Marroqui L et al (2010a) Glucocorticoids in vivo induce both insulin hypersecretion and enhanced glucose sensitivity of stimulus-secretion coupling in isolated rat islets. Endocrinology 151(1):85\u201395. \nhttps:\/\/doi.org\/10.1210\/en.2009-0704","journal-title":"Endocrinology"},{"issue":"3","key":"1510_CR39","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1111\/j.1748-1716.2010.02146.x","volume":"200","author":"A Rafacho","year":"2010","unstructured":"Rafacho A, Quallio S et al (2010b) The adaptive compensations in endocrine pancreas from glucocorticoid-treated rats are reversible after the interruption of treatment. Acta Physiol (Oxf) 200(3):223\u2013235. \nhttps:\/\/doi.org\/10.1111\/j.1748-1716.2010.02146.x","journal-title":"Acta Physiol (Oxf)"},{"issue":"3","key":"1510_CR40","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/S0029-7844(01)01780-X","volume":"99","author":"R Resnik","year":"2002","unstructured":"Resnik R (2002) Intrauterine growth restriction. Obstet Gynecol 99(3):490\u2013496. \nhttps:\/\/doi.org\/10.1016\/S0029-7844(01)01780-X","journal-title":"Obstet Gynecol"},{"key":"1510_CR41","doi-asserted-by":"publisher","DOI":"10.1186\/1824-7288-37-41","volume":"37","author":"T Saleem","year":"2011","unstructured":"Saleem T, Sajjad N et al (2011) Intrauterine growth retardation\u2014small events, big consequences. Ital J Pediatr 37:41. \nhttps:\/\/doi.org\/10.1186\/1824-7288-37-41","journal-title":"Ital J Pediatr"},{"issue":"2","key":"1510_CR42","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.taap.2013.11.009","volume":"274","author":"L Shen","year":"2014","unstructured":"Shen L, Liu Z et al (2014) Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats. Toxicol Appl Pharmacol 274(2):263\u2013273. \nhttps:\/\/doi.org\/10.1016\/j.taap.2013.11.009","journal-title":"Toxicol Appl Pharmacol"},{"issue":"10","key":"1510_CR43","doi-asserted-by":"publisher","first-page":"2279","DOI":"10.2337\/diabetes.50.10.2279","volume":"50","author":"RA Simmons","year":"2001","unstructured":"Simmons RA, Templeton LJ et al (2001) Intrauterine growth retardation leads to the development of type 2 diabetes in the rat. Diabetes 50(10):2279\u20132286. \nhttps:\/\/doi.org\/10.2337\/diabetes.50.10.2279","journal-title":"Diabetes"},{"issue":"3","key":"1510_CR44","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/j.toxlet.2012.09.007","volume":"214","author":"Y Tan","year":"2012","unstructured":"Tan Y, Liu J et al (2012) Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation. Toxicol Lett 214(3):279\u2013287. \nhttps:\/\/doi.org\/10.1016\/j.toxlet.2012.09.007","journal-title":"Toxicol Lett"},{"issue":"3","key":"1510_CR45","first-page":"215","volume":"23","author":"AA Varvarigou","year":"2010","unstructured":"Varvarigou AA (2010) Intrauterine growth restriction as a potential risk factor for disease onset in adulthood. J Pediatr Endocr Met 23(3):215\u2013224","journal-title":"J Pediatr Endocr Met"},{"issue":"4","key":"1510_CR46","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1046\/j.1365-3016.2003.00507.x","volume":"17","author":"T Vik","year":"2003","unstructured":"Vik T, Bakketeig LS et al (2003) High caffeine consumption in the third trimester of pregnancy: gender-specific effects on fetal growth. Paediatr Perinat Epidemiol 17(4):324\u2013331","journal-title":"Paediatr Perinat Epidemiol"},{"issue":"3","key":"1510_CR47","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.toxlet.2013.11.006","volume":"224","author":"LL Wang","year":"2014","unstructured":"Wang LL, Shen L et al (2014) Intrauterine metabolic programming alteration increased susceptibility to non-alcoholic adult fatty liver disease in prenatal caffeine-exposed rat offspring. Toxicol Lett 224(3):311\u2013318. \nhttps:\/\/doi.org\/10.1016\/j.toxlet.2013.11.006","journal-title":"Toxicol Lett"},{"issue":"1","key":"1510_CR48","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.taap.2015.09.007","volume":"289","author":"YM Wu","year":"2015","unstructured":"Wu YM, Luo HW et al (2015) Prenatal caffeine exposure induced a lower level of fetal blood leptin mainly via placental mechanism. Toxicol Appl Pharmacol 289(1):109\u2013116. \nhttps:\/\/doi.org\/10.1016\/j.taap.2015.09.007","journal-title":"Toxicol Appl Pharmacol"},{"issue":"3","key":"1510_CR49","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/j.taap.2012.08.016","volume":"264","author":"D Xu","year":"2012","unstructured":"Xu D, Wu Y et al (2012a) A hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic programmed alteration in offspring rats of IUGR induced by prenatal caffeine ingestion. Toxicol Appl Pharmacol 264(3):395\u2013403. \nhttps:\/\/doi.org\/10.1016\/j.taap.2012.08.016","journal-title":"Toxicol Appl Pharmacol"},{"key":"1510_CR50","doi-asserted-by":"publisher","unstructured":"Xu D, Zhang BJ et al (2012b) Caffeine-induced activated glucocorticoid metabolism in the hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats. PLoS One 7(9). \nhttps:\/\/doi.org\/10.1371\/journal.pone.0044497","DOI":"10.1371\/journal.pone.0044497"},{"issue":"2","key":"1510_CR51","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1017\/S0029665100000288","volume":"59","author":"C Yajnik","year":"2000","unstructured":"Yajnik C (2000) Interactions of perturbations in intrauterine growth and growth during childhood on the risk of adult-onset disease. Proc Nutr Soc 59(2):257\u2013265","journal-title":"Proc Nutr Soc"},{"issue":"10","key":"1510_CR52","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025167","volume":"6","author":"QX Yuan","year":"2011","unstructured":"Yuan QX, Chen L et al (2011) Postnatal pancreatic islet beta cell function and insulin sensitivity at different stages of lifetime in rats born with intrauterine growth retardation. PloS one 6(10):e25167. \nhttps:\/\/doi.org\/10.1371\/journal.pone.0025167","journal-title":"PloS one"}],"container-title":["The Science of Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00114-017-1510-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00114-017-1510-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00114-017-1510-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T08:49:28Z","timestamp":1513673368000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00114-017-1510-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,9]]},"references-count":52,"journal-issue":{"issue":"11-12","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["1510"],"URL":"https:\/\/doi.org\/10.1007\/s00114-017-1510-4","relation":{},"ISSN":["0028-1042","1432-1904"],"issn-type":[{"type":"print","value":"0028-1042"},{"type":"electronic","value":"1432-1904"}],"subject":[],"published":{"date-parts":[[2017,10,9]]},"article-number":"89"}}