{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T12:37:57Z","timestamp":1648643877261},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,9,11]],"date-time":"2008-09-11T00:00:00Z","timestamp":1221091200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nervenarzt"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1007\/s00115-008-2565-4","type":"journal-article","created":{"date-parts":[[2008,9,9]],"date-time":"2008-09-09T13:40:29Z","timestamp":1220967629000},"page":"62-67","source":"Crossref","is-referenced-by-count":0,"title":["Famili\u00e4re Alzheimer-Variante mit Amyloidangiopathie als Ausdruck einer APP-Gen-Duplikation"],"prefix":"10.1007","volume":"80","author":[{"given":"H.","family":"Axer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"H\u00fcge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Wilhelm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Axer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kunze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.R.","family":"Reichenbach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Freesmeyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Kohlhase","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Sauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.-J.","family":"B\u00e4r","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,9,11]]},"reference":[{"key":"2565_CR1","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.1161\/STROKEAHA.107.492033","volume":"38","author":"B\u00e4r","year":"2007","unstructured":"B\u00e4r KJ, Boettger MK, Seidler N et al. (2007) Influence of galantamine on vasomotor reactivity in Alzheimer\u2019s disease and vascular dementia due to cerebral microangiopathy. Stroke 38: 3186\u20133192","journal-title":"Stroke"},{"key":"2565_CR2","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1136\/jmg.2004.019901","volume":"41","author":"Borozdin","year":"2004","unstructured":"Borozdin W, Boehm D, Leipoldt M et al. (2004) SALL4 deletions are a common cause of Okihiro and acro-renal-ocular syndromes and confirm haploinsufficiency as the pathogenic mechanism. J Med Genet 41: e113","journal-title":"J Med Genet"},{"key":"2565_CR3","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/humu.9396","volume":"27","author":"Borozdin","year":"2006","unstructured":"Borozdin W, Steinmann K, Albrecht B et al. (2006) Detection of heterozygous SALL1 deletions by quantitative real time PCR proves the contribution of a SALL1 dosage effect in the pathogenesis of Townes-Brocks syndrome. Hum Mutat 27: 211\u2013212","journal-title":"Hum Mutat"},{"key":"2565_CR4","first-page":"316","volume":"28","author":"Haacke","year":"2007","unstructured":"Haacke EM, DelProposto ZS, Chaturvedi S et al. (2007) Imaging cerebral amyloid angiopathy with susceptibility-weighted imaging. Am J Neuroradiol 28: 316\u2013317","journal-title":"Am J Neuroradiol"},{"key":"2565_CR5","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1136\/jnnp.2004.059212","volume":"76","author":"Ragoschke-Schumm","year":"2005","unstructured":"Ragoschke-Schumm A, Axer H, Fitzek C et al. (2005) Intracerebral haemorrhage in CADASIL. J Neurol Neurosurg Psychiatry 76: 1606\u20131607","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2565_CR6","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1136\/jmg.2005.033456","volume":"42","author":"Raux","year":"2005","unstructured":"Raux G, Guyant-Mar\u00e9chal L, Martin C et al. (2005) Molecular diagnosis of autosomal dominant early onset Alzheimer\u2019s disease: an update. J Med Genet 42: 793\u2013795","journal-title":"J Med Genet"},{"key":"2565_CR7","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1148\/radiology.204.1.9205259","volume":"204","author":"Reichenbach","year":"1997","unstructured":"Reichenbach JR, Venkatesan R, Schillinger DJ et al. (1997) Small vessels in the human brain: MR venography with deoxyhemoglobin as an intrinsic contrast agent. Radiology 204: 272\u2013277","journal-title":"Radiology"},{"key":"2565_CR8","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1136\/jnnp.2006.113514","volume":"78","author":"Rovelet-Lecrux","year":"2007","unstructured":"Rovelet-Lecrux A, Frebourg T, Tuominen H et al. (2007) APP locus duplication in a Finnish family with dementia and intracerebral haemorrhage. J Neurol Neurosurg Psychiatry 78: 1158\u20131159","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2565_CR9","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/ng1718","volume":"38","author":"Rovelet-Lecrux","year":"2006","unstructured":"Rovelet-Lecrux A, Hannequin D, Raux G et al. (2006) APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet 38: 24\u201326","journal-title":"Nat Genet"},{"key":"2565_CR10","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1212\/WNL.56.7.979","volume":"56","author":"Tapiola","year":"2001","unstructured":"Tapiola T, Soininen H, Pirttil\u00e4 T (2001) CSF tau and Abeta42 levels in patients with Down\u2019s syndrome. Neurology 56: 979\u2013980","journal-title":"Neurology"},{"key":"2565_CR11","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S0010-9452(08)70683-X","volume":"43","author":"Snowden","year":"2007","unstructured":"Snowden JS, Stopford CL, Julien CL et al. (2007) Cognitive phenotypes in Alzheimer\u2019s disease and genetic risk. Cortex 43: 835\u2013845","journal-title":"Cortex"},{"key":"2565_CR12","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1212\/WNL.46.2.413","volume":"46","author":"Lehtovirta","year":"1996","unstructured":"Lehtovirta M, Soininen H, Helisalmi S et al. (1996) Clinical and neuropsychological characteristics in familial and sporadic Alzheimer\u2019s disease: Relation to apolipoprotein E polymorphism. Neurology 46: 413\u2013419","journal-title":"Neurology"},{"key":"2565_CR13","doi-asserted-by":"crossref","first-page":"2966","DOI":"10.1093\/brain\/awl237","volume":"129","author":"Cabrejo","year":"2006","unstructured":"Cabrejo L, Guyant-Mar\u00e9chal L, Laquerri\u00e8re A et al. (2006) Phenotype associated with APP duplication in five families. Brain 129: 2966\u20132976","journal-title":"Brain"}],"container-title":["Der Nervenarzt"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00115-008-2565-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00115-008-2565-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00115-008-2565-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T05:08:35Z","timestamp":1558588115000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00115-008-2565-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,11]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["2565"],"URL":"https:\/\/doi.org\/10.1007\/s00115-008-2565-4","relation":{},"ISSN":["0028-2804","1433-0407"],"issn-type":[{"value":"0028-2804","type":"print"},{"value":"1433-0407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,11]]}}}