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Bisher liegen nur unzureichende Kenntnisse zu Pr\u00e4valenz, Inzidenz, Verlauf und Prognose vor. Ebenso fehlen klinische Studien, aus denen sich Empfehlungen zum evidenzbasierten Management des Delirs bei IPS ableiten lassen.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Ziel der Arbeit\/Fragestellung<\/jats:title>\n<jats:p>Darstellung des aktuellen wissenschaftlichen Kenntnisstandes des Delirs beim IPS und Sensibilisierung f\u00fcr diese wichtige Krankheitsentit\u00e4t.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methoden<\/jats:title>\n<jats:p>Die Literatursuche wurde in PubMed durchgef\u00fchrt.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Ergebnisse<\/jats:title>\n<jats:p>Das IPS ist ein unabh\u00e4ngiger Risikofaktor f\u00fcr die Entwicklung eines Delirs. IPS-Patienten zeigen nach einem Delir anhaltende Verschlechterungen sowohl der Kognition als auch der motorischen Symptomatik.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Diskussion<\/jats:title>\n<jats:p>Bislang existieren keine validierten Bewertungsskalen zur Erkennung und Verlaufsbeurteilung des Delirs beim IPS. Pr\u00e4ventive und nichtpharmakologische Ma\u00dfnahmen sollten konsequent und strukturiert angewandt werden. Die medikament\u00f6se Behandlung mit Quetiapin und Clozapin ist bisher noch unzureichend untersucht, w\u00e4hrend andere Neuroleptika aufgrund ihrer dopaminantagonistischen Wirkung zur Behandlung des Delirs beim IPS kontraindiziert sind.<\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s00115-020-00876-2","type":"journal-article","created":{"date-parts":[[2020,1,27]],"date-time":"2020-01-27T14:02:43Z","timestamp":1580133763000},"page":"107-113","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Das Delir beim idiopathischen Parkinson-Syndrom","Delirium in idiopathic Parkinson\u2019s disease"],"prefix":"10.1007","volume":"91","author":[{"given":"C.","family":"Franke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Ebersbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,27]]},"reference":[{"key":"876_CR1","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1136\/jnnp.2005.083113","volume":"78","author":"D Aarsland","year":"2007","unstructured":"Aarsland\u00a0D, Bronnick\u00a0K, Ehrt\u00a0U, De Deyn\u00a0PP, Tekin\u00a0S, Emre\u00a0M, Cummings\u00a0JL (2007) Neuropsychiatric symptoms in patients with Parkinson\u2019s disease and dementia: frequency, profile and associated care giver stress. 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