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Besonders in der Behandlung von Menschen mit einer Schizophrenie k\u00f6nnten Hirnstimulationsverfahren eine Alternative oder Erg\u00e4nzung zu den etablierten Therapiestrategien darstellen. Die meist vorhandenen Positivsymptome k\u00f6nnen zumeist mit Antipsychotika ad\u00e4quat behandelt werden. Gerade bei Patienten mit Schizophrenie besitzen jedoch Negativsymptome einen \u00fcberdauernden Krankheitswert und beeinflussen den Verlauf durch globale Antriebsverarmung und beeintr\u00e4chtigte Kognition im allt\u00e4glichen Leben negativ. Dieser \u00dcbersichtsartikel stellt eine Zusammenfassung \u00fcber die verschiedenen nichtinvasiven Hirnstimulationsverfahren transkranielle Gleichstromstimulation (transcranial direct current stimulation, tDCS), Wechselstromstimulation (transcranial alternating current stimulation, tACS) sowie Rauschstromstimulation (transcranial random noise stimulation, tRNS) zur Behandlung der Negativsymptomatik bei Schizophrenie dar. Die neuen transkraniellen Hirnstimulationsverfahren k\u00f6nnten dabei helfen, gest\u00f6rte neuronale Vernetzungen wieder herzustellen und die Konnektivit\u00e4t vor allem der dorsolateralen pr\u00e4frontalen Anteile des Kortex zu verbessern. Einige Studien weisen auf eine Verbesserung der Negativsymptome durch Behandlung mit tDCS, tACS bzw. tRNS hin und k\u00f6nnten so neue Therapiem\u00f6glichkeiten in der Behandlung der Schizophrenie darstellen.<\/jats:p>","DOI":"10.1007\/s00115-021-01065-5","type":"journal-article","created":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T14:33:20Z","timestamp":1611585200000},"page":"41-50","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Transkranielle elektrische Hirnstimulationsverfahren zur Behandlung der Negativsymptomatik bei Schizophrenie","Transcranial electrical brain stimulation methods for treatment of negative symptoms in schizophrenia"],"prefix":"10.1007","volume":"93","author":[{"given":"Nikolas","family":"Haller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alkomiet","family":"Hasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Padberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Strube","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandro","family":"da Costa Lane Valiengo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre R.","family":"Brunoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome","family":"Brunelin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Palm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,25]]},"reference":[{"key":"1065_CR1","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.psychres.2015.11.042","volume":"235","author":"SM Agarwal","year":"2016","unstructured":"Agarwal\u00a0SM, Bose\u00a0A, Shivakumar\u00a0V et\u00a0al (2016) Impact of antipsychotic medication on transcranial direct current stimulation (tDCS) effects in schizophrenia patients. 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