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Mechanische Engpasssyndrome peripherer Nerven oder Nervenwurzeln, raumfordernde L\u00e4sionen des Zentralnervensystems, chronisch-entz\u00fcndliche neurologische Erkrankungen oder eine Polyneuropathie k\u00f6nnen einen neuropathischen Pruritus verursachen. Selbst wenn die Identifizierung der zugrunde liegenden neurologischen Erkrankung erfolgreich ist, ist eine kausale Therapie nicht immer m\u00f6glich, sodass eine effiziente symptomatische Behandlung die einzige therapeutische Option darstellt. 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