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W\u00e4hrend Viren bevorzugt das Myelon und die Radizes direkt infizieren oder eine sekund\u00e4re Immunantwort triggern, neigen Bakterien, Pilze und Parasiten zur Bildung von Abszessen, Granulomen und Zysten und k\u00f6nnen wie destruierende Osteomyelitiden zu einer sekund\u00e4ren Myelonkompression f\u00fchren. Die \u00e4tiologische Eingrenzung eines akuten\/subakuten spinalen Prozesses erfolgt anhand der klinischen Pr\u00e4sentation, der zeitlichen Dynamik der Symptomentwicklung, des Immunstatus, der Bildgebung und mikrobieller\/molekularbiologischer Untersuchungen von Liquor und Serum. Aufgrund des Tropismus einzelner Erreger zu bestimmten Faserstrukturen und Zellverb\u00e4nden im R\u00fcckenmark kann in Zusammenschau mit der Klinik, der Bildgebung und der Expositionsanamnese oft bereits zeitnah eine fokussierte Abkl\u00e4rung und Diagnose erfolgen. In diesem Artikel wird auf wichtige Erreger einer spinalen\/paraspinalen Infektion, deren geografisches Vorkommen und die klinische und bildgebende Pr\u00e4sentation unter besonderer Ber\u00fccksichtigung der anatomisch-topografischen Lokalisation und aktueller epidemiologischer Entwicklungen eingegangen. Der Ausbruch von Poliomyelitiserkrankungen durch zirkulierende Impfstoffpolioviren (cVDPV) sei hier im Speziellen erw\u00e4hnt.<\/jats:p>","DOI":"10.1007\/s00115-023-01439-x","type":"journal-article","created":{"date-parts":[[2023,2,23]],"date-time":"2023-02-23T14:04:47Z","timestamp":1677161087000},"page":"287-295","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Infektionen des R\u00fcckenmarks und der angrenzenden Strukturen","Infections of the spinal cord and adjacent structures"],"prefix":"10.1007","volume":"94","author":[{"given":"Bettina","family":"Pfausler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verena","family":"Rass","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Lindner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,2,23]]},"reference":[{"key":"1439_CR1","doi-asserted-by":"publisher","first-page":"bcr2013010423","DOI":"10.1136\/bcr-2013-010423","volume":"2013","author":"SF Bari","year":"2013","unstructured":"Bari\u00a0SF, Khan\u00a0A, Lawson\u00a0T (2013) C reactive protein may not be reliable as a\u00a0marker of severe bacterial infection in patients receiving tocilizumab. 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